Browse Items · NEOMED Bibliography Database

Effects of Substrate Size and Orientation on Quadrupedal Gait Kinematics in Mouse Lemurs (Microcebus murinus).

As the smallest living primate, the mouse lemur is a suitable model for reconstructing the locomotor mechanisms by which primate ancestors might have responded to the challenges of an arboreal environment. In this study, we tested the effects of…

Tags: 2016, Animals, Biomechanical Phenomena, Cheirogaleidae/*physiology, Department of Anatomy & Neurobiology, Female, Gait/*physiology, Journal of experimental zoology. Part A, Ecological genetics and physiology, Kemp Addison D, Male, NEOMED College of Medicine, Shapiro Liza J, Young Jesse W

Hibernation does not reduce cortical bone density, area or second moments of inertia in woodchucks (Marmota monax).

Long periods of inactivity in most mammals result in bone loss that may not be completely recoverable during an individual's lifetime regardless of future activity. Prolonged inactivity is normal during hibernation, but it remains uncertain whether…

Tags: 2012, Animals, Bone and Bones/metabolism, Bone Density/*physiology, Doherty Alison H, Female, Femur/metabolism, Frampton Jason D, Hibernation/*physiology, Humerus/metabolism, Journal of morphology, Male, Marmota/growth & development/*metabolism, Tibia/metabolism, Vinyard Christopher J

Distribution and origin of corticotropin-releasing factor-immunoreactive axons in the female rat lumbosacral spinal cord.

Corticotropin-releasing factor (CRF) is a neuropeptide traditionally known for its hormonal role in the hypothalamic/pituitary/adrenal stress axis. However, CRF has been reported in axons in sites that may be considered outside of the direct stress…

Estrogen receptor-alpha and neural circuits to the spinal cord during pregnancy.

Estrogen receptor immunoreactivity and mRNAs are present in spinal cord neurons in locations that are associated with sensory and autonomic innervation of female reproductive organs. The present study was undertaken to examine the expression of…

Hypothalamic paraventricular axons projecting to the female rat lumbosacral spinal cord contain oxytocin immunoreactivity.

Oxytocin-containing axons project from the hypothalamic paraventricular nucleus to the neurohypophysis and thoracic spinal cord to ultimately influence uterine contractions and autonomic activity, respectively. Whether or not oxytocin-immunoreactive…

Tags: *Synaptic Transmission, 2001, Animals, Axons/*physiology, Female, Immunohistochemistry, Journal of neuroscience research, Lumbosacral Region, Nerve Fibers/metabolism/physiology, Oxytocin/*metabolism, Papka R E, Paraventricular Hypothalamic Nucleus/*physiology, Puder B A, Rats, Spinal Cord/*physiology, Sprague-Dawley

Activation and circuitry of uterine-cervix-related neurons in the lumbosacral dorsal root ganglia and spinal cord at parturition.

Stimulation of the uterine cervix at parturition activates neural circuits involving primary sensory nerves and supraspinally projecting neurons of the lumbosacral spinal cord, resulting in output of hypothalamic neurohormones. Dorsal root ganglia…

Glutamate and metabotropic glutamate receptors associated with innervation of the uterine cervix during pregnancy: receptor antagonism inhibits c-Fos expression in rat lumbosacral spinal cord at parturition.

Dorsal root ganglia (DRG) neurons connect the spinal cord and uterine cervix, and are activated at parturition with subsequent stimulation of secondary neurons in the spinal dorsal horn and autonomic areas. Neuropeptide neurotransmitters and…

Tags: 2007, Animals, Cervix Uteri/*innervation, Department of Anatomy & Neurobiology, Excitatory Amino Acid Antagonists/pharmacology, Female, Ganglia, Gene Expression Regulation/drug effects/*physiology, Ghosh Chaitali, Glutamates/*metabolism, Hafemeister Jen, Journal of neuroscience research, Lumbosacral Region, Messenger/biosynthesis, Metabotropic Glutamate 5, Metabotropic Glutamate/*metabolism, Miller Kenneth E, NEOMED College of Medicine, Neurons/drug effects, Oncogene Proteins v-fos/metabolism, Papka Raymond E, Parturition/*metabolism, Pregnancy/*metabolism, Pyridines/pharmacology, Rats, Receptor, Receptors, Reverse Transcriptase Polymerase Chain Reaction/methods, RNA, Spinal Cord/drug effects/*physiology, Spinal/cytology, Sprague-Dawley, Storey-Workley Megan, Usip Sharon, Vesicular Glutamate Transport Protein 1/metabolism

Inhibition of nerve growth factor-stimulated neurite outgrowth by methylamine-modified alpha 2-macroglobulin.

alpha 2-Macroglobulin (alpha 2M) is a rather ubiquitous protein in extracellular spaces of mammals. It is an inhibitor of endopeptidases, can be modified by aliphatic amines, and combines with a number of hormones/cytokines such as beta-nerve growth…

Evaluation of extended antibiotic prophylaxis in patients undergoing indicated non-cosmetic panniculectomy at the time of gynecologic surgery.

BACKGROUND: Panniculectomy at time of gynecologic surgery is used to improve visualization and prevent major complications in morbidly obese patients. We examine the role of extended antibiotic prophylaxis in prevention of surgical site infections…

Agreement Between an Automated Volume Breast Scanner and Handheld Ultrasound for Diagnostic Breast Examinations.

OBJECTIVES: To compare the agreement and interobserver variability of diagnostic handheld ultrasound (US) and a single volume on an automated breast volume scanner (ABVS) and to determine whether there was a significant difference if the ABVS was…

Telepresent Focused Assessment With Sonography for Trauma Examination Training Versus Traditional Training for Medical Students: A Simulation-Based Pilot Study.

OBJECTIVES: Telepresent education is becoming an important modality in medical education, as it provides a means for instructors to lead education sessions via videoconferencing technologies. This study aimed to compare the effectiveness of…

Quantitative skin assessment using spatial frequency domain imaging (SFDI) in patients with or at high risk for pressure ulcers.

BACKGROUND AND OBJECTIVE: Pressure ulcers (PU) are a significant problem facing the health system in the United States. Here, we present preliminary case studies demonstrating feasibility of Spatial Frequency Domain Imaging (SFDI) to assess skin…

A plant lignan, 3'-O-methyl-nordihydroguaiaretic acid, suppresses papillomavirus E6 protein function, stabilizes p53 protein, and induces apoptosis in cervical tumor cells.

Persistent infection with oncogenic human papillomaviruses (HPVs) is the most important factor in the induction of uterine cervical cancer, a leading cause of cancer mortality in women worldwide. Upon cell transformation, continual expression of the…

Suppression of inflammatory cascade is implicated in methyl amooranin-mediated inhibition of experimental mammary carcinogenesis.

Breast cancer represents the second leading cause of cancer-related deaths among women worldwide and preventive therapy could reverse or delay the devastating impact of this disease. Methyl-amooranin (methyl-25-hydroxy-3-oxoolean-12-en-28-oate,…

Gender differences in the association between antidepressant use and restless legs syndrome.

Contradictory results have been reported for the association between antidepressant use and Restless Legs Syndrome (RLS). Our aim was to clarify the relationship and examine possible gender differences. We interviewed 1,693 veterans receiving primary…

Modulation of angiogenesis by dietary phytoconstituents in the prevention and intervention of breast cancer.

Breast cancer is the leading cause of cancer-related deaths for women in the United States and the rest of the world. About 8% of women develop breast cancer during the course of their lives. Dietary habits are closely associated with both the risk…

Tags: *Diet, 2012, Anticarcinogenic Agents/*chemistry/*pharmacology, Bishayee Anupam, Breast Neoplasms/*blood supply/*prevention & control, Female, Gopalan Ashwin, Humans, Malus/chemistry, Molecular nutrition & food research, Neovascularization, Pathologic/metabolism/prevention & control, Petit Danielle M, Reuben Sharon C

Prevalence and Predictors of Metformin Prescribing in Adults with Type 2 Diabetes Mellitus: A National Cross-Sectional Study.

OBJECTIVE: Metformin is the first-line oral type 2 diabetes treatment. Despite an abundance of evidence, metformin is routinely underused. This study evaluated the rates of metformin use in an appropriate outpatient type 2 diabetes population and…

Striatal dopamine output is compromised within +/- BDNF mice.

We reported previously that mice lacking one brain-derived neurotrophic factor (BDNF) allele demonstrate elevated striatal dopamine (DA) concentrations but impaired behavioral responses involving the nigrostriatal dopaminergic (NSDA) system. To test…

Effect of estrogen upon methamphetamine-induced neurotoxicity within the impaired nigrostriatal dopaminergic system.

In the present study, we investigated whether estrogen remains effective as a neuroprotectant within an impaired nigrostriatal dopaminergic (NSDA) system of gonadectomized female and male mice. In Experiment 1, mice were treated with four different…

Nomifensine alters sex differences in striatal dopaminergic function.

A series of three experiments are presented in which the acute effects of the catecholamine reuptake inhibitor, nomifensine, upon striatal dopaminergic function are compared in female and male mice. In Experiment 1, treatment with nomifensine (5 mg…

What happens when effective outpatient civil commitment is terminated?

Outpatient civil commitment can be effective in slowing the revolving door for selected patients, but it may not be the best mechanism for ensuring treatment over time.

Wound seeding associated with endometrial cancer.

We report a patient with well-differentiated adenocarcinoma of the endometrium who developed a recurrence in the anterior abdominal wall probably secondary to wound seeding at the time of her original surgery. She underwent total abdominal…

Tags: *Neoplasm Recurrence, *Neoplasm Seeding, 1994, Adenocarcinoma/pathology/radiotherapy/*surgery, Adult, Cross B, Curtis M G, Department of Internal Medicine, Endometrial Neoplasms/pathology/radiotherapy/*surgery, Female, Gynecologic oncology, Hopkins M P, Humans, Jenison E L, Local, NEOMED College of Medicine, Phosphorus Radioisotopes/therapeutic use, Rehmus E, Tantri M D

Uterine cervix adenocarcinoma with both human papillomavirus type 18 and tumor suppressor gene p53 mutation from a woman having an intact hymen.

Human papillomavirus (HPV) type 18 DNA was found in an aggressively invasive adenocarcinoma tumor from a woman who had an intact hymen and denied any prior sexual intercourse. The viral DNA was detected within the tumor tissue by polymerase chain…

Pure embryonal rhabdomyosarcoma of the fallopian tube.

Rhabdomyosarcoma is a neoplasm of childhood which commonly arises in the genitourinary tract. Reported locations include the bladder, prostate, paratestis, vagina, uterus, cervix, and ovary. Rhabdomyosarcomas have been reported to occur in the…

Tags: 1997, Adolescent, Buchwalter C L, Department of Radiology, Embryonal/*pathology, Fallopian Tube Neoplasms/*pathology, Female, Fromm M, Gynecologic oncology, Hart W R, Humans, Jenison E L, Mehta V T, NEOMED College of Medicine, Obstetrics and gynecology, Rhabdomyosarcoma

Alternative medicine in gynecologic oncology: A case report.

A patient with Stage IIB squamous cell cancer of the cervix presented 10 days into her primary radiation therapy with neutropenic fever and diarrhea requiring hospitalization and delay in treatment. The patient's history revealed extensive use of…

Tags: *Complementary Therapies, 2000, Carcinoma, Diarrhea/*etiology, Female, Fever/*etiology, Gynecologic oncology, Hopkins M P, Hospitalization, Humans, Medical History Taking, Medicinal/*adverse effects, Middle Aged, Neutropenia/*etiology, Plants, Squamous Cell/drug therapy/*radiotherapy, Time Factors, Uterine Cervical Neoplasms/drug therapy/*radiotherapy, von Gruenigen V E

Lichen striatus.

Tags: 2016, Adolescent, Age Factors, Child, Cutis, Diagnosis, Differential, Female, Graham Jacqueline N, Hossler Eric W, Humans, Inflammation/*diagnosis/pathology, Lichenoid Eruptions/*diagnosis/epidemiology/pathology, Male, Preschool, Sex Factors

Metastatic carcinoma of the spine with neurologic complications: an autopsy review.

We conducted post-mortem examinations on 12 patients who had documented metastatic carcinoma to the spine with attendant neurologic complications. The examinations were studied to determine the location of the metastatic lesion in relation to the…

Tags: 1993, Adult, Aged, Autopsy, Female, Humans, Leeson M C, Male, Middle Aged, Orthopedics, Spinal Cord Compression/*etiology/pathology, Spinal Neoplasms/*complications/pathology/*secondary, Zechmann J P

The cost of laparoscopic versus open cholecystectomy in a community hospital.

This retrospective study reviewed the hospital and professional costs, charges, and reimbursements for laparoscopic cholecystectomy (lap chole) and open cholecystectomy (open chole) and compared the two procedures. There was no significant difference…

Laparoscopic hernia repair. Three-year experience.

The basis of laparoscopic transabdominal preperitoneal repair (LTPR) of herniae rests upon the utilization of a prosthetic screen to cover hernia defects. Preperitoneal prosthetic screen interposition reproduces the effect of the inguinal shutter…

Tags: 1995, 80 and over, Adolescent, Adult, Aged, Female, Follow-Up Studies, Hernia, Humans, Inguinal/*surgery, Kavic M S, Laparoscopy/*methods, Male, Middle Aged, Postoperative Complications, Prostheses and Implants, Reoperation, Surgical endoscopy

Recognition of depression by internal medicine residents.

We studied the ability of internal medicine residents to recognize depressive symptoms in a population of lower socio-economic primary care patients. Four hundred twenty patients completed the short form of the Beck Depression Inventory (BDI).…

Mice transgenic for simian immunodeficiency virus nef are immunologically compromised.

An intact nef gene is essential for rapid development of immunodeficiency in human immunodeficiency virus and simian immunodeficiency virus infections. To assess the role of nef in the immune response, mice transgenic for SIV nef were constructed and…

The effect of estrogen administration in vivo upon catecholamine release in vitro from superfused hypothalamic tissue of ovariectomized pre-pubertal and adult mice.

In the present report we examined the effects of estrogen upon catecholamine release from superfused medial basal hypothalamic tissue fragments of pre-pubertal ovariectomized CD-1 mice. Prepubertal mice treated with estradiol benzoate (EB–5…

Tags: *Ovariectomy, 1994, Aging/*metabolism, Animals, Attaran M, Catecholamines/*metabolism, Dluzen D, Dopamine/metabolism, Estradiol/*pharmacology, Female, Hypothalamus/*drug effects/metabolism, Journal of endocrinological investigation, Liu B, Mice, Norepinephrine/metabolism, Organ Size/drug effects, Potassium/pharmacology, Uterus/drug effects/growth & development

Rectal trauma and associated hemorrhage with the use of the ConvaTec Flexi-Seal fecal management system: report of 3 cases.

The management of fecal incontinence is a struggle to maintain patient hygiene and limit the transmission of nosocomial infections. Intrarectal devices that cause diversion and collection of the fecal stream have been used with increasing frequency.…

Tags: 2010, Aged, Catheterization/*adverse effects/*instrumentation, Chase Daniel, Coughlin Lisa, Diseases of the colon and rectum, Fecal Incontinence/*therapy, Female, Gastrointestinal Hemorrhage/*etiology/surgery, Heaton Bren, Hemostasis, Humans, Male, Metha Jeet, Middle Aged, Pressure Ulcer/*etiology/surgery, Rectum/*injuries/surgery, Sparks Dorothy, Surgical/methods

Demethyleneberberine alleviates inflammatory bowel disease in mice through regulating NF-kappaB signaling and T-helper cell homeostasis.

OBJECTIVE: The activation of NF-kappaB signaling and unbalance of T-helper (Th) cells have been reported to play a key role in the pathogenesis of colitis. Cortex Phellodendri Chinensis (CPC) is commonly used to treat inflammation and diarrhea.…

Tags: 2017, Animals, Anti-Inflammatory Agents/*pharmacology/therapeutic use, Berberine/*analogs & derivatives/pharmacology/therapeutic use, Chen Yingying, Colitis, Colon/drug effects/immunology/pathology, Cytokines/immunology, Dextran Sulfate, DMB, Female, Helper-Inducer/*drug effects/immunology, Homeostasis/drug effects, Immunoglobulin G/blood, Inbred C57BL, Inflammation research : official journal of the European Histamine Research Society ... [et al.], Inflammatory Bowel Diseases/blood/chemically induced/drug therapy/*immunology, Li Rui-Yan, Mice, NF-kappa B/*antagonists & inhibitors/immunology, NF-kappaB, RAW 264.7 Cells, Reactive Oxygen Species/metabolism, Shi Mei-Jing, Signal Transduction/drug effects, Spleen/cytology, T-Lymphocytes, Th cell, Xu Xin-Xin, Yan Yan, Zhang Miao, Zhang Yu-Bin, Zhao Xiao-Tong, Zhao Ya-Xing

Tethered cord syndrome in a 24-year-old woman presenting with urinary retention.

We discuss a case of newly diagnosed tethered cord syndrome (TCS) in a

Tags: 2007, Adult, Bologna Raymond, Cerone Jeff, Female, Flora Robert, Hematuria/*etiology, Humans, International urogynecology journal and pelvic floor dysfunction, Laminectomy, Lipoma/complications/surgery, Memo Mark, Neural Tube Defects/*complications/*diagnosis/surgery, Tareen Basir, Urinary Retention/*etiology, Urodynamics/physiology

Disseminated lymphangiomatosis presenting with massive chylothorax.

BACKGROUND: Lymphangiomatosis is a disease characterized by involvement of various body constituents and can involve the skeletal system, connective tissues, and visceral organs. MATERIALS AND METHODS: We present a case of a

Tags: 2000, Bone Neoplasms/complications/*diagnosis, Child, Chylothorax/diagnosis/*etiology, Female, Goyal M, Humans, Konez O, Lymphangioma/complications/*diagnosis, Magnetic Resonance Imaging, Malignant/etiology, Pediatric radiology, Pleural Effusion, Ribs/diagnostic imaging/pathology, Tomography, Vyas P K, X-Ray Computed

Nasal chondromesenchymal hamartoma: radiographic and histopathologic analysis of a rare pediatric tumor.

Nasal chondromesenchymal hamartoma (NCMH) is an extremely rare benign pediatric tumor that was described in 1998. Only 19 cases are reported in the literature. We present a 15-year-old girl with nasal obstruction and recurrent sinusitis. Her medical…

Tags: 2007, Adolescent, Cartilage Diseases/*diagnostic imaging/pathology/surgery, Diagnosis, Differential, Esguerra Jorge, Female, Hamartoma/*diagnostic imaging/pathology/surgery, Humans, Johnson Craig, Mesoderm/diagnostic imaging/pathology, Nagaraj Usha, Paranasal Sinus Diseases/*diagnostic imaging/pathology/surgery, Pediatric radiology, Radiography, Wasdahl Daniel, Wurzbach Douglas

Congenital solid neck mass: a unique presentation of Langerhans cell histiocytosis.

Langerhans cell histiocytosis (LCH) presenting in the neonatal period is very rare. In most cases, a self-limited cutaneous disease is the exclusive manifestation. We report an unusual case of neonatal LCH presenting with a large congenital solid…

Tags: 2008, Color, Contrast Media – Administration and Dosage, Contrast Media/administration & dosage, Diagnosis, Differential, Disease Attributes, Doppler, Female, Follow-Up Studies, Goske Marilyn J, Head and Neck Neoplasms, Head and Neck Neoplasms – Diagnosis, Head and Neck Neoplasms – Therapy, Head and Neck Neoplasms/*congenital/*diagnosis/therapy, Histiocytosis, Human, Humans, Infant, Langerhans-Cell, Langerhans-Cell – Diagnosis, Langerhans-Cell – Therapy, Langerhans-Cell/*congenital/*diagnosis/therapy, Neck – Radiography, Neck – Surgery, Neck – Ultrasonography, Neck/diagnostic imaging/surgery, Newborn, Pediatric radiology, Prospective Studies, Radiographic Image Enhancement – Methods, Radiographic Image Enhancement/methods, Radiography, Rare Diseases, Steele Mark, Tantiwongkosi Bundhit, Thoracic – Methods, Thoracic/methods, Tomography, Ultrasonography, X-Ray Computed

Pediatric appendiceal ultrasound: accuracy, determinacy and clinical outcomes.

BACKGROUND: Ultrasonography is considered the most appropriate initial imaging study in the evaluation of acute appendicitis in children but has recently come under criticism with reports of low specificity and high indeterminate study rates,…

No rheumatoid arthritis in ancient Egypt: a reappraisal.

Antiquity of rheumatoid arthritis (RA) remains controversial, and its origins in Americas or in the Old World are disputed. Proponents of the latter frequently refer to RA in ancient Egypt, but validity of those claims has never been examined. Review…

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