Browse Items · NEOMED Bibliography Database

Pediatric appendiceal ultrasound: accuracy, determinacy and clinical outcomes.

BACKGROUND: Ultrasonography is considered the most appropriate initial imaging study in the evaluation of acute appendicitis in children but has recently come under criticism with reports of low specificity and high indeterminate study rates,…

Acquired inhibitor to factor VIII in small cell lung cancer: a case report and review of the literature.

Acquired hemophilia (antibodies or inhibitors to factor VIII) is the most common acquired disease affecting clotting factors. It has been described in association with autoimmune disease, malignancy, dermatologic disorders, in the postpartum period,…

Tags: 2001, Ahmed F, Annals of hematology, Carcinoma, Crock R, Department of Internal Medicine, Factor VIII/*antagonists & inhibitors, Humans, Lara L, Lung Neoplasms/*chemistry, Male, Middle Aged, NEOMED College of Medicine, Rutecki G W, Shwaiki A, Small Cell/*chemistry, Whittier F C

No rheumatoid arthritis in ancient Egypt: a reappraisal.

Antiquity of rheumatoid arthritis (RA) remains controversial, and its origins in Americas or in the Old World are disputed. Proponents of the latter frequently refer to RA in ancient Egypt, but validity of those claims has never been examined. Review…

Beyond thermoregulation: metabolic function of cetacean blubber in migrating bowhead and beluga whales.

The processes of lipid deposition and utilization, via the gene leptin (Lep), are poorly understood in taxa with varying degrees of adipose storage. This study examines how these systems may have adapted in marine aquatic environments inhabited by…

Inversion appendectomy acting as a lead point for intussusception.

A case of ileocecal intussusception following inversion appendectomy during a Ladd's procedure for malrotation is presented. In this case, the inverted ischemic appendiceal remnant was presumed to have acted as the leadpoint for the intussusception.…

Tags: 2008, Appendectomy/*methods, Appendicitis/diagnosis/*surgery, Arora Amit, Besner Gail E, Caniano Donna A, Cecal Diseases/diagnosis/*surgery, Duodenum/abnormalities, Hammond Sue, Humans, Ileal Diseases/diagnosis/*surgery, Infant, Intestinal Volvulus/diagnosis/*surgery, Intussusception/diagnosis/*surgery, Male, Pediatric surgery international, Postoperative Complications/diagnosis/*surgery

Novel thiazolidinedione mitoNEET ligand-1 acutely improves cardiac stem cell survival under oxidative stress.

Ischemic heart disease (IHD) is a leading cause of death worldwide, and regenerative therapies through exogenous stem cell delivery hold promising potential. One limitation of such therapies is the vulnerability of stem cells to the oxidative…

Differential regulation of TRPV1 channels by H2O2: implications for diabetic microvascular dysfunction.

We demonstrated previously that TRPV1-dependent coupling of coronary blood flow (CBF) to metabolism is disrupted in diabetes. A critical amount of H2O2 contributes to CBF regulation; however, excessive H2O2 impairs responses. We sought to determine…

Impairment of pH gradient and membrane potential mediates redox dysfunction in the mitochondria of the post-ischemic heart.

The mitochondrial electrochemical gradient (Deltap), which comprises the pH gradient (DeltapH) and the membrane potential (DeltaPsi), is crucial in controlling energy transduction. During myocardial ischemia and reperfusion (IR), mitochondrial…

GABAergic and non-GABAergic projections to the superior colliculus from the auditory brainstem.

The superior colliculus (SC) contains an auditory space map that is shaped by projections from several subcortical auditory nuclei. Both GABAergic (inhibitory) and excitatory cells contribute to these inputs, but there are contradictory reports…

Increased transperitoneal bacterial translocation in laparoscopic surgery.

BACKGROUND: The indications for laparoscopic surgery have expanded to include diseases possibly associated with peritonitis such as appendicitis, perforated peptic ulcers, and diverticulitis. The safety of carbon dioxide (CO2) pneumoperitoneum in the…

Appendicitis in the elderly: a change in the laparoscopic era.

BACKGROUND: Appendicitis in elderly patients is associated with significant morbidity and mortality. Early and correct diagnosis together with minimally invasive surgery can lead to more favorable outcomes than occurred in the prelaparoscopic era.…

Revisiting classification of pain from bone metastases as mild, moderate, or severe based on correlation with function and quality of life.

PURPOSE: The objective of our study was to determine the optimal cut points for classification of pain scores as mild, moderate, and severe based on interference with function and quality of life (QOL). METHODS: We evaluated 822 patients who…

Tags: *Quality of Life, *Severity of Illness Index, 2016, 80 and over, Adolescence, Adolescent, Adult, Aged, Babington Scott, Bone metastases, Bone Neoplasms, Bone Neoplasms – Complications, Bone Neoplasms/*complications/secondary, Brief pain inventory, Brundage Michael, Chow Edward, Demas William F, Ding Keyue, Female, Functional interference, Funding Source, Hartsell William F, Hoskin Peter, Human, Humans, Male, Meyer Ralph M, Middle Age, Middle Aged, Nabid Abdenour, Ong Francisca, Pain – Classification, Pain – Etiology, Pain Measurement – Methods, Pain Measurement/*methods, Pain severity, Pain/*classification/etiology, Parulekar Wendy R, Quality of Life, Questionnaires, Re-irradiation, Roos Daniel, Severity of Illness Indices, Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, Survival, van der Linden Yvette M, van Tienhoven Geertjan, Wilson Carolyn F, Wong Rebecca K S, Wu Jackson S Y, Young Adult, Zhu Liting

Alteration in L-DOPA evoked dopamine and DOPAC output under conditions of impaired vesicular dopamine storage.

We examined the effect of L-dihydroxyphenylalanine (L-DOPA) infusion in vitro upon dopamine (DA) and dihydroxyphenylacetic acid (DOPAC) output from superfused corpus striatum of vehicle and reserpine or tetrabenazine (TBZ) treated male rats.…

Tags: 1998, 3, 4-Dihydroxyphenylacetic Acid/*metabolism, Animals, Dluzen D E, Dopamine Agents/*pharmacology, Dopamine/*metabolism, Journal of neural transmission (Vienna, Austria : 1996), Levodopa/*pharmacology, Male, Pharmaceutical Vehicles, Rats, Reserpine/pharmacology, Sprague-Dawley, Synaptic Vesicles/*drug effects/metabolism, Tetrabenazine/pharmacology, Xu K

Sex differences in striatal dopaminergic function within heterozygous mutant dopamine transporter knock-out mice.

The issue of whether a deletion of the dopamine transporter (DAT) allele (+/- DAT) would differentially alter striatal dopamine (DA) and dihydroxyphenylacetic acid (DOPAC) concentrations and DA release upon potassium and methamphetamine (MA)…

CPPD complicating other forms of inflammatory arthritis.

Calcium pyrophosphate deposition (CPPD) disease is confirmed as equally common in rheumatoid arthritis by synovial fluid and macroscopic skeletal examination. Furthermore, differential frequencies in rheumatoid arthritis and spondyloarthropathy…

Tags: *Calcium Pyrophosphate/metabolism, 2007, Arthritis, Bone and Bones/metabolism/pathology, Chondrocalcinosis/*complications/metabolism/pathology, Clinical rheumatology, Female, Humans, Male, Rheumatoid/*complications/metabolism/pathology, Rothschild Bruce, Synovial Fluid/metabolism

Identification of plasma microRNA expression profile in radiographic axial spondyloarthritis-a pilot study.

At present, there are no studies that have established a microRNA (miRNA)-based signature profile in patients with radiographic axial spondyloarthritis (rad-axial SpA), and we hypothesized that these patients may have aberrantly expressed circulating…

Caudate body (CB) sign: new early CT sign of hyperacute anterior cerebral circulation infarction.

This case series describes the caudate body (CB) sign noted in computed tomography (CT) scans of patients who presented to the Emergency Department (ED) clinically manifesting symptoms suggestive of anterior cerebral circulation infarction. This sign…

Tags: *Tomography, 2011, 80 and over, Aged, Ahmed Shamima Y, Basal Ganglia – Pathology, Brain Infarction/*diagnostic imaging, Caudate Nucleus/*pathology, Emergency Medicine, Emergency radiology, Female, Humans, Infarction – Radiography, Khalaf Hamzah Suhail, Kurman Andrew J, Male, Tomography, X-Ray Computed, Young Adult

Complete remission in a patient with metastatic mixed adenocarcinoma/extrapulmonary small cell carcinoma of the prostate.

Approximately 10% of all extra-pulmonary small cell carcinoma (EPSCC) arises in the prostate either as de novo mixed adenocarcinoma with small cell components or a pure small cell carcinoma. Extensive disease carries a median survival of about 10…

Tags: 2011, Adenocarcinoma/diagnosis/*secondary, Androgen Antagonists/therapeutic use, Bone Neoplasms/*drug therapy/*secondary, Brammer Jonathan Edward, Carcinoma, Cisplatin/therapeutic use, Combined Modality Therapy, Etoposide/therapeutic use, Humans, International journal of clinical oncology, Lulla Premal, Lung Neoplasms/diagnosis/*secondary, Lynch Garrett Rush, Male, Middle Aged, Prostatic Neoplasms/*drug therapy/metabolism/*pathology, Remission Induction, Small Cell/diagnosis/*secondary

Long-Lasting forward Suppression of Spontaneous Firing in Auditory Neurons: Implication to the Residual Inhibition of Tinnitus.

Tinnitus is the perception of a sound that has no external source. Sound stimuli can suppress spontaneous firing in auditory neurons long after stimulus offset. It is unknown how changes in sound stimulus parameters affect this forward suppression.…

Who do you think you are? Medical student socioeconomic status and intention to work in underserved areas.

A frequently cited rationale for increasing the participation of students from low socioeconomic status (SES) backgrounds is that it will create a workforce who will choose to work in low SES and medically underserviced communities. Two theoretical…

The Help-Seeking Experiences of Parents of Children with a First-Episode of Psychosis.

The objective was to understand the experiences of parents as they sought psychological and specialized medical services for a loved one having a first episode of psychosis. The research method was qualitative and the data gathering was done through…

Tags: *Help-Seeking Behavior, 2015, Adolescence, Adolescent, Adolescents and young adults, Adult, Affective Disorders, Bonfine Natalie, Child Behavior, Community mental health journal, Department of Family & Community Medicine, Department of Psychiatry, Diagnostic Errors, Early Intervention, Families, Female, First episode psychosis, Health Services Accessibility, Help Seeking Behavior – Ohio, Human, Humans, Interviews as Topic, Knepp Kristen, Male, Munetz Mark R, NEOMED College of Medicine, Ohio, Parental Attitudes, Parents, Parents – Psychosocial Factors, Parents/*psychology, Pathways to treatment, Patient Acceptance of Health Care/*psychology, Professional development, Psychosocial, Psychotic – In Adolescence, Psychotic Disorders/diagnosis/*psychology/therapy, Qualitative Studies, Semi-Structured Interview, Skubby David, Support, Tracy Hattie, Treatment Delay, Young Adult

Cognitive Behavioral Therapy for Psychosis (CBT-p) Delivered in a Community Mental Health Setting: A Case Comparison of Clients Receiving CBT Informed Strategies by Case Managers Prior to Therapy.

This exploratory case comparison examines the influence of case management activities on engagement and progress in psychotherapy for clients with schizophrenia. Six clients were recruited to participate in ten sessions of Cognitive Behavioral…

Tags: *Case Managers, *CBT-p, *Cognitive behavioral techniques for psychosis, *Cognitive behavioral therapy for psychosis, *Community Mental Health Services, *Continuum of care, *Schizophrenia, 2017, Adult, Case Management, Case-Control Studies, Cognitive Behavioral Therapy/*methods, Cognitive Therapy – Methods, Community mental health journal, Community Mental Health Services, Comparative Studies, Continuity of Patient Care, Department of Psychiatry, Evidence-Based, Exploratory Research, Female, Human, Humans, Knepp Kristen A, Male, Middle Aged, Montesano Vicki L, Munetz Mark R, NEOMED College of Medicine, Outcome Assessment, Professional Practice, Program Implementation – Methods, Psychotic Disorders – Therapy, Psychotic Disorders/*therapy, Schizophrenia, Sivec Harry J, Skubby David, Surveys and Questionnaires

Disease Burden Among Individuals with Severe Mental Illness in a Community Setting.

This study examines the prevalence of comorbid physical health conditions within a community sample of individuals with severe mental illness (SMI), compares them to a matched national sample without SMI, and identifies which comorbidities create the…

Translating Interventions that Target Criminogenic Risk Factors for use in Community Based Mental Health Settings.

This study explored facilitators and barriers associated with engaging criminogenic interventions in community mental health service settings. Focus groups and guided large group discussions were conducted with 46 consumers, providers and…

Lacking a Primary Care Physician Is Associated With Increased Suffering in Patients With Severe Mental Illness.

We evaluated the relationship between lack of a primary care physician (PCP) and patients with severe mental illness (SMI), who have poorer health and experience more suffering. Using a blinded retrospective record review of 137 patients with SMI,…

Tags: *Health Services Accessibility, *Primary Health Care, 2017, Adolescence, Adolescent, Adult, Aged, Amerine Jenna, Boltri John M, Clasen Mark E, Community, Comorbid conditions, Cost of Illness, Department of Family & Community Medicine, Economic Aspects of Illness, Female, Health outcomes, Health Services Accessibility, Hospitalization, Hospitals, Humans, Life Style, Lifestyle problems, Male, Mental Disorders – Complications, Mental Disorders – Psychosocial Factors, Mental Disorders – Therapy, Mental Disorders/complications/*psychology/*therapy, Middle Age, Middle Aged, NEOMED College of Medicine, Olsen Cynthia G, Preventative services, Primary Health Care, Psychological – Etiology, Psychological – Psychosocial Factors, Psychological/etiology/*psychology, Retrospective Design, Retrospective Studies, Stress, The journal of primary prevention, Young Adult

Immune mediated neurologic dysfunction as a paraneoplastic syndrome in renal cell carcinoma.

OBJECTIVE: To describe a case of cerebellar ataxia associated with renal cell carcinoma. CASE REPORT: A 53-year-old Caucasian male with a history of Schizophrenia presented with generalized weakness, nausea, vomiting, severe weight loss, and…

Tags: 2008, Antibodies/blood, Autoantibodies/analysis, Carcinoma, Department of Internal Medicine, Friedman Norman, Hagel Christian, Haller Nairmeen Awad, Hippocalcin/immunology/metabolism, Humans, Johnson Vijay, Journal of neuro-oncology, Kidney Neoplasms/*complications, Male, Middle Aged, NEOMED College of Medicine, Nervous System Diseases/etiology/*immunology/pathology, Paraneoplastic Syndromes/*complications/*etiology, Renal Cell/*complications

Is mortality due to primary malignant brain and other central nervous system tumors decreasing?

Primary malignant brain and other central nervous system tumors (BT) are a rare cancer that causes morbidity and mortality disproportionate to their incidence. This study presents the most up-to-date mortality data for malignant BT in the United…

Estimating the annual frequency of synchronous brain metastasis in the United States 2010-2013: a population-based study.

Brain metastases (BM) are one of the most common types of brain tumors and are a relatively common event in the disease process for several high-incidence cancer types, including breast and lung cancers. Historically, information on metastases…

Minimal clinically important differences in the EORTC QLQ-C30 and brief pain inventory in patients undergoing re-irradiation for painful bone metastases.

PURPOSE: The EORTC QLQ-C30 and the Brief Pain Inventory (BPI) are validated tools for measuring quality of life (QOL) and the impact of pain in patients with advanced cancer. Interpretation of these instrument scores can be challenging and it is…

Tags: *Bone metastases, *Brief pain inventory, *EORTC QLQ-C30, *Minimal Clinically Important Difference, *Minimal clinically important differences, *Radiation, 2018, 80 and over, Adolescence, Adolescent, Adult, Aged, Babington Scott, Bone Metastases – Radiotherapy, BONE metastasis, BONE metastasis – Treatment, Bone Neoplasms/*complications/radiotherapy/secondary, Brief pain inventory, Brundage Michael, Cancer Patients, CANCER radiotherapy, Chow Edward, Clinical Assessment Tools, Demas William F, Ding Keyue, Female, Funding Source, Haas Rick, Hartsell William F, Hoskin Peter, Human, Humans, Instrument Scaling, LONGITUDINAL method, Male, Meyer Ralph M, Middle Age, Middle Aged, Nabid Abdenour, Pain Management, Pain/*diagnosis, Prospective Studies, Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, Quality of Life/*psychology, Questionnaires, Raman Srinivas, RANDOMIZED controlled trials, Re-Irradiation/*adverse effects, Reoperation, Repeat Procedures, RESEARCH funding, Roos Daniel, SCALING (Social sciences), Secondary Analysis, Surveys and Questionnaires, van der Linden Yvette M, Wiggenraad Ruud, Wilson Carolyn F, Wong Rebecca K S, Wu Jackson S Y, Young Adult, Zhu Liting

Salvianolate reduces murine myocardial ischemia and reperfusion injury via ERK1/2 signaling pathways in vivo.

OBJECTIVE: To analyze the effects of salvianolate on myocardial infarction in a murine in vivo model of ischemia and reperfusion (I/R) injury. METHODS: Myocardial I/R injury model was constructed in mice by 30 min of coronary occlusion followed by 24…

Tags: *MAP Kinase Signaling System/drug effects, 2017, Animal Studies, Animals, Blotting, Cardiotonic Agents/pharmacology/therapeutic use, Chinese journal of integrative medicine, Chinese medicine, Descriptive Statistics, extracellular signal-regulated kinase 1/2, Flavonoids/pharmacology, Guo Liheng, Heart Ventricle, Heart Ventricles/drug effects/pathology, Huang Dong-Hui, Huang Hai-Ding, Huang Xin, In Vivo Studies, Inbred C57BL, ischemia and reperfusion injury, Left, Male, Mice, Mitogen-Activated Protein Kinase 1/*metabolism, Mitogen-Activated Protein Kinase 3/*metabolism, Molecular Structure, Myocardial Ischemia – Drug Therapy, Myocardial Reperfusion Injury – Drug Therapy, Myocardial Reperfusion Injury/*drug therapy/enzymology/pathology, Organ Size/drug effects, P-Value, Phosphorylation, Phosphorylation/drug effects, Plant Extracts – Administration and Dosage, Plant Extracts/chemistry/pharmacology/*therapeutic use, protein kinase B, Protein Kinase Inhibitors – Administration and Dosage, Protein Kinase Inhibitors/pharmacology, Protein Kinases – Analysis, Protein Kinases – Drug Effects, Qi Jianyong, salvianolate, Signal Transduction, Staining and Labeling, Wang Lei, Western, Wu Jiashin, Yu Juan, Zhang Minzhou, Zhou Miao

Group A streptococcus necrotizing fasciitis.

Necrotizing fasciitis due to Group A streptococcus has been observed with increasing frequency over the past decade. Appropriate management requires rapid recognition of this life-threatening infection and expeditious antimicrobial therapy as well as…

Signet Ring Cell Carcinoma of the Ampulla of Vater with Early Development of Bone Metastasis: Case Report and Review of the Rare Malignancy.

Tags: 2016, Ampulla of Vater/*pathology/surgery, Bone Neoplasms/*secondary/surgery, Carcinoma, Cocieru Andrei, Common Bile Duct Neoplasms/*pathology/surgery, Damania Rahul, Humans, Journal of gastrointestinal cancer, Male, Middle Aged, Prognosis, Signet Ring Cell/*pathology/surgery, Weaver Joshua

Non-health Care Facility Medication Errors Associated with Hormones and Hormone Antagonists in the United States.

INTRODUCTION: Hormones and hormone antagonists are frequently associated with medication errors and may result in important adverse outcomes. The purpose of this study is to investigate non-health care facility (non-HCF) medication errors associated…

Adverse reactions to aspartame: double-blind challenge in patients from a vulnerable population.

This study was designed to ascertain whether individuals with mood disorders are particularly vulnerable to adverse effects of aspartame. Although the protocol required the recruitment of 40 patients with unipolar depression and a similar number of…

Tags: 1993, Adult, Aspartame/*adverse effects/*therapeutic use, Biological psychiatry, Cross-Sectional Studies, Depressive Disorder/diagnosis/*drug therapy/psychology, Double-Blind Method, Eye Diseases/etiology/physiopathology, Female, Green-Waite R J, Headache/etiology, Hudak R, Humans, Male, Middle Aged, Placebos, Psychiatric Status Rating Scales, Vision Disorders/etiology/physiopathology, Walton R G

Castration reduces potassium-stimulated norepinephrine release from superfused olfactory bulbs of male rats.

In order to investigate the possible relationship among the olfactory bulb (OB), norepinephrine (NE) and gonadal steroids, we measured NE release from superfused anterior and posterior OB in intact and castrated male rats (Expt. I) as well as in…

Tags: *Orchiectomy, 1991, Animals, Brain research, Dluzen D, Guan X B, Inbred Strains, Kinetics, Male, Norepinephrine/*metabolism, Olfactory Bulb/drug effects/*physiology, Potassium/*pharmacology, Rats, Reference Values, Testosterone/*pharmacology

Morphological heterogeneity within the cingulate cortex in rat: a horseradish peroxidase transport study.

We compared the connections of two areas within rat cingulate cortex, the Cg1/Cg2 area vs the Cg3 area, by iontophoresing small quantities of wheatgerm agglutinin-horseradish peroxidase (WGA-HRP) into either of these two divisions and identifying…

Puberty acceleration in female mice induced with a partially purified male urine extract: effects on catecholamine release from the olfactory bulbs and hypothalamus.

In the present experiment peri-pubertal female mice were treated with a partially purified puberty accelerating urine extract (PAUE). Mice treated with the PAUE showed an advance in the onset of puberty as indicated by significantly increased uterine…

Tags: *Sex Characteristics, 1992, Animals, Brain research, Catecholamines/*metabolism, Dluzen D, Female, Guan X, Hypothalamus, Inbred Strains, Male, Mice, Middle/*metabolism, Olfactory Bulb/*metabolism, Sexual Maturation/*physiology, Urine/*physiology, Vandenbergh J G

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) reduces norepinephrine concentrations in the olfactory bulbs of male mice.

Male retired breeder C57/Bl and CD-1 mice were treated with either MPTP or its vehicle. At 7-10 days post-treatment, catecholamine concentrations within the olfactory bulbs (OB) and hypothalamus were determined. Norepinephrine concentrations within…

Tags: *Sex Characteristics, 1-Methyl-4-phenyl-1, 1992, 2, 3, 6-tetrahydropyridine/*pharmacology, Animals, Brain research, Dluzen D E, Dopamine/metabolism, Drug Resistance/genetics, Inbred C57BL, Inbred Strains, Male, Mice, Norepinephrine/*metabolism, Olfactory Bulb/*metabolism, Osmolar Concentration

A single restraint stress exposure potentiates analgesia induced by intrathecally administered DAGO.

In rats, restraint exposure potentiates the magnitude and duration of analgesia following both the peripheral and intracerebroventricular administration of several opioid agonists as compared to non-stressed controls. It has been suggested that the…

Depletion of olfactory bulb norepinephrine by 6-OHDA disrupts chemical cue but not social recognition responses in male rats.

In the present experiment, 6-OHDA was infused directly into the olfactory bulb (OB) to produce a localized neurotoxic lesion. Habituation/dishabituation behavioral tests were then conducted to measure recognition responses to chemical cues (urine as…

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