Browse Items (38 total)
- Tags: Department of Pharmaceutical Sciences, 2017
Alternative microglial activation is associated with cessation of progressive dopamine neuron loss in mice systemically administered lipopolysaccharide.
Tags: 2017, Alam Gelerah, Animals, Astrocytes/immunology/pathology, Beier Eric E, Cell Death/physiology, Corpus Striatum/immunology/pathology, Cytokines/metabolism, Department of Pharmaceutical Sciences, Disease Progression, Dopaminergic Neurons/*immunology/pathology, Edler Melissa, Inbred C57BL, Inflammation/pathology/physiopathology, Lipopolysaccharides/*toxicity, Male, Messenger/metabolism, Mice, Microglia/*immunology/pathology, Neal Matthew, NEOMED College of Pharmacy, Nerve Degeneration/*immunology/pathology, Neurobiology of disease, Neurodegenerative Diseases/immunology/pathology, Neuroimmunomodulation/physiology, Random Allocation, Richardson Jason R, RNA, Time Factors, Wu Long-Jun
Developmental pyrethroid exposure causes long-term decreases of neuronal sodium channel expression.
Tags: 2017, Animals, BDNF, Brain-Derived Neurotrophic Factor/metabolism, Cerebral Cortex/*drug effects/growth & development/metabolism, Corpus Striatum/*drug effects/growth & development/metabolism, Deltamethrin, Department of Pharmaceutical Sciences, Female, Inbred C57BL, Insecticides/*toxicity, Magby Jason P, Male, Messenger/metabolism, Mice, NEOMED College of Pharmacy, Neurodevelopmental, Neurons/*drug effects/metabolism, Neurotoxicology, Nitriles/*toxicity, Pregnancy, Prenatal Exposure Delayed Effects/*metabolism, Pyrethrins/*toxicity, Pyrethroid, Richardson Jason R, RNA, Sodium channel, Voltage-Gated Sodium Channels/*metabolism
Early Evidence of Low Bone Density and Decreased Serotonergic Synthesis in the Dorsal Raphe of a Tauopathy Model of Alzheimer's Disease.
Tags: *Alzheimer Disease/complications/genetics/pathology, *Alzheimer's disease, *bone density, *microtubule-associated protein, *serotonin, *tau proteins, *tauopathies, 2017, Age Factors, Alzheimer's disease, Alzheimer's Disease – Complications, Alzheimer's Disease – Pathology, Animal, Animal Studies, Animals, Biological, Body Composition, Body Composition/genetics, Body Weight, Body Weight/genetics, Bone Density – Physiology, Bone Density/*physiology, Bone Diseases – Etiology, Bone Diseases/*etiology, Brain Stem – Pathology, Dengler-Crish Christine M, Department of Pharmaceutical Sciences, Disease Models, Dorsal Raphe Nucleus/*pathology, Female, Inbred C57BL, Journal of Alzheimer's disease : JAD, Male, Mice, Models, NEOMED College of Pharmacy, Nerve Tissue Proteins, Nerve Tissue Proteins – Metabolism, Neurodegenerative Diseases, Neurodegenerative Diseases – Complications, Neurons – Metabolism, Neurons – Pathology, Neurons/metabolism/pathology, Oxidoreductases – Metabolism, Phosphorylation, Serotonin – Metabolism, Serotonin/*metabolism, Smith Matthew A, tau Proteins/*genetics/metabolism, Tauopathies/complications/genetics, Transgenic, Tryptophan Hydroxylase/metabolism, Wilson Gina N
Emerging strategies of targeting lipoprotein lipase for metabolic and cardiovascular diseases.
Tags: 2017, Animals, Cardiovascular Diseases/drug therapy/*enzymology, Darvesh Altaf S, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Drug Discovery Today, Geldenhuys Werner J, Humans, Lin Li, Lipoprotein Lipase/chemistry/*metabolism, Metabolic Diseases/drug therapy/*enzymology, NEOMED College of Graduate Studies, NEOMED College of Pharmacy, Sadana Prabodh
Engineering Alkoxyphenacyl-Polycarbonate Nanoparticles for Potential Application in Near-Infrared Light-Modulated Drug Delivery via Photon Up-Conversion Process
Tags: 2017, 800 nm, alkoxylphenacyl-based polycarbonates, Andrews J H, Biocompatibility, Chamsaz E A, Chemistry, Department of Pharmaceutical Sciences, Doxorubicin, Drug Release, Journal Article, Journal of nanoscience and nanotechnology, Joy A, luminescence, Materials Science, mesoporous-silica, nanocrystals, Nanotechnology, Near-Infrared Light, NEOMED College of Pharmacy, Oyewumi M O, photodynamic therapy, Physics, release, Science & Technology - Other Topics, Stimuli-responsive, upconverting nanoparticles, uv, Wehrung D
Enhancing Studies of Pharmacodynamic Mechanisms via Measurements of Metabolic Flux: Fundamental Concepts and Guiding Principles for Using Stable Isotope Tracers.
Tags: 2017, Animals, Chen Ying, Daurio Natalie A, Department of Pharmaceutical Sciences, Drug Discovery/*methods, Erion Mark D, Humans, Isotope Labeling, Isotopes/chemistry, Johns Douglas G, Kasumov Takhar, Kelley David E, McLaren David G, Metabolic Flux Analysis/*methods, Milot Denise, NEOMED College of Pharmacy, Previs Stephen F, Roddy Thomas P, The Journal of pharmacology and experimental therapeutics, Wang Sheng-Ping, Water/chemistry/metabolism, Zhou Haihong
Evaluating the Changing Financial Burdens for Graduating Pharmacists.
Tags: 2017, American journal of pharmaceutical education, Career Choice, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Education, Humans, Income, Mattingly T Joseph 2nd, NEOMED College of Pharmacy, new practitioners, personal finance, Pharmacists/*economics, Pharmacy, Pharmacy/*economics, Salaries and Fringe Benefits/economics, Schools, student debt, Students, Training Support/*economics, Ulbrich Timothy R
Identifying motivators and barriers to student completion of instructor evaluations: A multi-faceted, collaborative approach from four colleges of pharmacy.
Tags: *Attitude of Health Personnel, *Barriers, *Faculty, *Focus group, *Instructor evaluation, *Motivators, *Student, 2017, Adult, Backo Jennifer Lynn, Currents in pharmacy teaching & learning, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Education, Educational Measurement/methods/*standards, Faculty/standards, Female, Humans, Male, McAuley James W, Metzger Anne H, Middle Aged, Motivation, NEOMED College of Pharmacy, Ohio, Pharmacy/*methods, Pharmacy/*psychology, Sobota Kristen Finley, Students, Surveys and Questionnaires, Ulbrich Timothy, Universities/organization & administration
Impact of Tranexamic Acid in Total Knee and Total Hip Replacement.
Tags: 2017, Aged, Antifibrinolytic Agents/adverse effects/therapeutic use, Arthroplasty, Blood Transfusion, Blood Transfusion/statistics & numerical data, Boyle Jaclyn A, Case-Control Studies, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Descriptive Statistics, Female, Hemoglobins – Analysis, Hemoglobins/metabolism, Hip, Hip/*methods, Human, Humans, Journal of pharmacy practice, Knee, Knee/*methods, Length of Stay – Evaluation, Length of Stay/statistics & numerical data, Male, NEOMED College of Pharmacy, Outcome Assessment, Replacement, Retrospective Design, Retrospective Studies, Soric Mate M, total hip replacement, total knee replacement, tranexamic acid, Tranexamic Acid – Administration and Dosage, Tranexamic Acid/adverse effects/*therapeutic use, Venous Thromboembolism – Risk Factors, Venous Thromboembolism/epidemiology
Increased serotransferrin and ceruloplasmin turnover in diet-controlled patients with type 2 diabetes.
Tags: *Ceruloplasmin, *Deamidation, *Heavy water metabolic labeling, *High resolution mass spectrometry, *Iron metabolism, *LC-MS/MS, *Non-enzymatic glycation, *Oxidative Stress, *Protein Processing, *Proteome dynamics, *Serotransferrin, *Type 2 diabetes mellitus, 2017, Adult, Amino Acid Sequence, Bena James, Case-Control Studies, Ceruloplasmin/genetics/*metabolism, Department of Pharmaceutical Sciences, Deuterium/metabolism, Diabetes Mellitus, Diabetic, Diet, Female, Free radical biology & medicine, Gene Expression Regulation, Glycated Hemoglobin A/genetics/metabolism, Glycosylation, Golizeh Makan, Humans, Ilchenko Serguei, Iron/*metabolism, Isotope Labeling, Kashyap Sangeeta R, Kasumov Takhar, Lee Kwangwon, Male, Middle Aged, NEOMED College of Pharmacy, Osme Abdullah, Oxidation-Reduction, Oxidative Stress, Post-Translational, Proteolysis, Sadygov Rovshan G, Transferrin/genetics/*metabolism, Type 2/diet therapy/genetics/*metabolism/pathology
Inhibition Of Angiopoietin-like 3 Expression Is A Potential Mechanism Of Activation Of Lipoprotein Lipase And Of Lipid Lowering By Metformin
Tags: 2017, Arteriosclerosis Thrombosis and Vascular Biology, Burke J R, Cardiovascular System & Cardiology, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Drugs, Geldenhuys W J, Hematology, Hyperlipidemia, Journal Article or Conference Abstract Publication, Lin L, Lipases, NEOMED College of Graduate Studies, NEOMED College of Pharmacy, Sadana P
Injury-induced gp130 cytokine signaling in peripheral ganglia is reduced in diabetes mellitus.
Tags: *Axon regeneration, *Axotomy, *Diabetes, *Neuropathy, *Peripheral nervous system, 2017, Animal, Animals, Antibiotics, Antineoplastic/toxicity, Blood Glucose/drug effects, Body Weight/drug effects, Crish Samuel D, Cytokine Receptor gp130/genetics/*metabolism, Cytokines/metabolism, DeFrancesco Alicia, Department of Pharmaceutical Sciences, Diabetes Mellitus, Disease Models, Experimental neurology, Experimental/chemically induced/complications/*pathology, Fasting/blood, Filous Angela R, Gene Expression Regulation/*physiology, Hyperalgesia/etiology, Hyperglycemia/etiology, Inbred C57BL, Lindborg Jane A, Male, Malhotra Nisha A, Mice, NEOMED College of Pharmacy, Nerve Degeneration/*etiology/pathology, Nerve Tissue Proteins/metabolism, Niemi Jon P, Pain Measurement, Signal Transduction/drug effects/*physiology, Streptozocin/toxicity, Superior Cervical Ganglion/drug effects/*metabolism, Sweating/drug effects, Wilson Gina N, Zhou Bowen, Zigmond Richard E
Is the Public Service Loan Forgiveness program right for you?
Tags: 2017, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, debt, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Financial – United States, loan forgiveness, loan repayment, NEOMED College of Pharmacy, Notareschi Vincent, Program Evaluation, student loan, Training Support, Ulbrich Timothy R, United States
It's Time to Broaden the Conversation About the Student Debt Crisis Beyond Rising Tuition Costs.
Tags: *debt, *personal finance, *student loans, 2017, American journal of pharmaceutical education, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Education, Humans, Income, Kirk Loren M, NEOMED College of Pharmacy, Pharmacists/economics, Pharmacy, Pharmacy/*economics, Students, Ulbrich Timothy R
Mechanisms of Gene-Environment Interactions in Parkinson's Disease.
Tags: *Alpha-synuclein, *ATP13A2, *Gene-Environment Interaction, *Genetic Predisposition to Disease, *Manganese, *Paraquat, *Parkinson Disease, *Parkinson's disease, *Rotenone, 2017, Current environmental health reports, Department of Pharmaceutical Sciences, Environmental Exposure/*adverse effects, Fleming Sheila M, Herbicides/adverse effects, Humans, Insecticides/adverse effects, Mutation/genetics, NEOMED College of Pharmacy, Paraquat/adverse effects, Risk Factors, Rotenone/adverse effects
Metabolic Vulnerability In The Neurodegenerative Disease Glaucoma
Tags: 2017, amyotrophic-lateral-sclerosis, axon, Axonopathy, Department of Pharmaceutical Sciences, Frontiers in neuroscience, glucose-transporter glut3, glycogen-synthase kinase-3, Harun-Or-Rashid M, Inman D M, Journal Article or Conference Abstract Publication, lactate, Mitochondria, monocarboxylate transporters, mouse white-matter, NEOMED College of Pharmacy, neuron lactate-shuttle, Neuropathy, Neurosciences & Neurology, optic, optic-nerve head, retinal ganglion-cells, self-destruction, slow wallerian degeneration, Wallerian degeneration
Methods Used by Colleges and Schools of Pharmacy to Prepare Student Pharmacists for Careers in Academia.
Tags: *Career Choice, *Students, 2017, Academia, American journal of pharmaceutical education, Attitude of Health Personnel, Boyle Jaclyn A, Career, Clifford Kalin M, Curriculum, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Dy-Boarman Eliza A, Education, Faculty, Graduate, Haines Seena L, Humans, NEOMED College of Pharmacy, Peeters Michael J, Pharmaceutical, Pharmacists, Pharmacy, Pharmacy/*methods, Pharmacy/*organization & administration, Schools, Societies, Student preparation, Summa Maria A, Surveys and Questionnaires, Training, United States, Willson Megan N
MicroRNA-223 ameliorates alcoholic liver injury by inhibiting the
Tags: *CYTOKINES, *ETHANOL, *FATTY LIVER, *Inflammation, *LEUKOCYTES, 2017, Adult, Alanine Transaminase/blood, Alcoholic/genetics/*metabolism/pathology, Alcoholism/*blood/complications, Animals, Aspartate Aminotransferases/blood, Bilirubin/blood, Binge Drinking/*blood/complications, Cai Yan, Cao Haixia, Case-Control Studies, Central Nervous System Depressants/administration & dosage, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Down-Regulation, Ethanol/administration & dosage, Female, Feng Dechun, Gao Bin, Gao Yanhang, Gao Yueqiu, Gut, He Yong, Humans, Inbred C57BL, Interleukin-6/genetics/metabolism, Li Man, Liangpunsakul Suthat, Liver Diseases, Male, Mice, MicroRNAs/*blood/*genetics, Middle Aged, NADPH Oxidases/genetics/metabolism, NEOMED College of Medicine, NEOMED College of Pharmacy, Neutrophils/*metabolism, Ramirez Teresa, Reactive Oxygen Species/metabolism, Ross Ruth A, Up-Regulation, Xu Ming-Jiang, Young Adult, Zhang Ping, Zhou Zhou
MitoNEET (CISD1) Knockout Mice Show Signs of Striatal Mitochondrial Dysfunction and a Parkinson's Disease Phenotype.
Tags: *Aging, *Disease Models, *drug discovery, *mitochondrial dysfunction, *mitoNEET, 2017, ACS chemical neuroscience, Animal, Animals, Benkovic Stanley A, Brown Candice M, Corpus Striatum/*metabolism/*pathology, Crish Samuel D, Darvesh Altaf S, Department of Pharmaceutical Sciences, Geldenhuys Werner J, Inbred C57BL, Iron-Binding Proteins/genetics/*metabolism, Knockout, Lin Li, Male, Membrane Proteins/genetics/*metabolism, Mice, Mitochondria/*metabolism/*pathology, NEOMED College of Pharmacy, Parkinson Disease/*metabolism/pathology, Richardson Jason R, Sullivan Patrick G, Yonutas Heather M
Patient Awareness and Expectations of Pharmacist Services During Hospital Stay.
Tags: *Anticipation, *Awareness, *Health Knowledge, 2017, 80 and over, Adolescent, Adult, Aged, Attitudes, Betka Eric M, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Descriptive Statistics, Female, Health Services Accessibility, Hospital, Hospital/methods/*statistics & numerical data, Human, Humans, Inpatients, Inpatients/*psychology, Journal of pharmacy practice, King Philip K, Male, Marketing, Marketing/methods, Martin Steven J, Middle Aged, NEOMED College of Pharmacy, Patient Attitudes, patient awareness, Patient Education, patient expectations, Pharmacists/*statistics & numerical data, Pharmacy Service, pharmacy services, Practice, Pretest-Posttest Design, Professional Role, Professional-Patient Relations, Psychological, Social Marketing, Summated Rating Scaling, Surveys, Surveys and Questionnaires, United States, Young Adult
Preparing students for residency interviews through a residency interview boot camp.
Tags: *Career Mobility, *Internship and Residency, *Interviewing skills, *Mock interview, *Residency training, 2017, Adult, Boyle Jaclyn A, Currents in pharmacy teaching & learning, Curriculum/trends, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Education, Feedback, Female, Humans, interviews, Interviews as Topic/*methods/standards, Male, NEOMED College of Pharmacy, pharmacy residency, Pharmacy/*psychology, Pharmacy/methods, residency interviews, Students, Ulbrich Timothy R, Workforce
Pyrethroid Insecticides Directly Activate Microglia Through Interaction With Voltage-Gated Sodium Channels.
Tags: *deltamethrin, *intracellular sodium., *Microglia, *neurodegeneration, *Neuroinflammation, *permethrin, *pyrethroids, *tetrodotoxin, *tumor necrosis factor, *Voltage-gated sodium channels, 2017, Animals, Cell Line, Department of Pharmaceutical Sciences, Dose-Response Relationship, Drug, Hossain Muhammad M, Inbred C57BL, Insecticides/*toxicity, Ion Channel Gating/*drug effects, Liu Jason, Mice, Microglia/*drug effects/metabolism, NEOMED College of Pharmacy, Pyrethrins/*toxicity, Richardson Jason R, Sodium Channels/*drug effects, Toxicological sciences : an official journal of the Society of Toxicology, Transformed, Tumor Necrosis Factor-alpha/metabolism
Signal Transduction Mechanisms of Alcoholic Fatty Liver Disease: Emer ging Role of Lipin-1.
Tags: 2017, alcoholic fatty liver disease, Alcoholic/*metabolism/pathology, AMP-Activated Protein Kinases/metabolism, Animals, Current molecular pharmacology, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Ethanol/chemistry/*metabolism, Fatty Liver, Humans, Inflammation, Inflammation/metabolism, Jogasuria Alvin, Lee Kwangwon, Lee Yoon-Kwang, Lipid Metabolism, Lipin-1, Liver/metabolism, NEOMED College of Graduate Studies, NEOMED College of Medicine, NEOMED College of Pharmacy, Phosphatidate Phosphatase/*metabolism, Sadana Prabodh, Signal Transduction, Sirtuin 1/metabolism, transcriptional regulators, Wu Jiashin, You Min, Zhang Yanqiao
Single low doses of MPTP decrease tyrosine hydroxylase expression in the absence of overt neuron loss.
Tags: 1-Methyl-4-phenyl-1, 2, 2017, 3, 6-tetrahydropyridine/*administration & dosage, Alam Gelareh, Animals, Burchfield Shelbie L, Catecholamines/metabolism, Cell Count, Corpus Striatum/*drug effects/metabolism, Department of Pharmaceutical Sciences, Dopamine, Dopamine transporter, Dopaminergic Neurons/*drug effects/metabolism, Edler Melissa, Inbred C57BL, Male, Mice, MPTP, MPTP Poisoning, NEOMED College of Pharmacy, Neurotoxicology, Parkinsonian Disorders/*metabolism/*pathology, Richardson Jason R, Stereology, Substantia Nigra/*drug effects/metabolism, Tyrosine 3-Monooxygenase/*metabolism, Tyrosine hydroxylase, Vesicular monoamine transporter
Structure-activity and in vivo evaluation of a novel lipoprotein lipase (LPL) activator.
Tags: *Diabetes, *High-fat diet, *Homology modeling, *Hyperlipidemia, *Lipoprotein lipase, *Liver cirrhosis, *Obesity, 2017, Animals, Benzeneacetamides/chemical synthesis/chemistry/*pharmacology, Bioorganic & medicinal chemistry letters, Caporoso Joel, Darvesh Altaf S, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Dose-Response Relationship, Drug, Geldenhuys Werner J, Imidazoles/chemical synthesis/chemistry/*pharmacology, Lee Yoon-Kwang, Leeper Thomas C, Lin Li, Lipoprotein Lipase/*metabolism, Mice, Molecular Docking Simulation, Molecular Structure, NEOMED College of Graduate Studies, NEOMED College of Medicine, NEOMED College of Pharmacy, Sadana Prabodh, Structure-Activity Relationship
The Role Of Amadori-glycation In High Density Lipoprotein Dysfunction And Oxidative Stress In Patients With Diabetes
Tags: 2017, Apolipoproteins, Arteriosclerosis Thrombosis and Vascular Biology, Atherosclerosis, Cardiovascular System & Cardiology, Department of Pharmaceutical Sciences, Golizeh M, Hematology, Ilchenko S, Insulin Resistance, Journal Article or Conference Abstract Publication, Kashyap S, Kasumov T, Lee K, NEOMED College of Pharmacy, Smith J, Wang S H
Therapeutic Delivery of Simvastatin Loaded in PLA-PEG Polymersomes Resulted in Amplification of Anti-inflammatory Effects in Activated Microglia.
Tags: *Drug Delivery Systems, *Inflammation, *Microglia, *neuroprotection, *polymersomes, *simvastatin, 2017, Animals, Anti-Inflammatory Agents/*pharmacology, Department of Pharmaceutical Sciences, Inbred BALB C, Interleukin-6/antagonists & inhibitors/biosynthesis, Lactates/*administration & dosage, Manickavasagam Dharani, Mice, Microglia/*drug effects, NEOMED College of Pharmacy, Nitric Oxide/antagonists & inhibitors/biosynthesis, Novak Kimberly, Oyewumi Moses O, Polyethylene Glycols/*administration & dosage, Simvastatin/*administration & dosage/pharmacology, The AAPS journal, Tumor Necrosis Factor-alpha/antagonists & inhibitors/biosynthesis
Toolkit for US colleges/schools of pharmacy to prepare learners for careers in academia.
Tags: *Academia, *Career, *Student preparation, *Training, 2017, Boyle Jaclyn A, Clifford Kalin M, Currents in pharmacy teaching & learning, Curriculum/trends, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Dy-Boarman Eliza A, Education, Faculty, Haines Seena L, Humans, NEOMED College of Pharmacy, Peeters Michael J, Pharmacy/*education/organization & administration, Pharmacy/*methods/organization & administration, Pharmacy/*psychology, Students, Summa Maria A, Universities/organization & administration/trends, Willson Megan N, Workforce
TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy.
Tags: *Alzheimers disease, *Immunity, *Inflammation, *Tauopathy, *TREM2, 2017, Allan Kevin, Animal, Animals, Bemiller Shane M, Crish Samuel D, Department of Pharmaceutical Sciences, Disease Models, Formica Shane V, Humans, Immunologic/*deficiency, Inbred C57BL, Kokiko-Cochran Olga N, Lamb Bruce T, Landreth Gary E, Lasagna-Reeves Cristian A, McCray Tyler J, Membrane Glycoproteins/*deficiency, Mice, Microglia/metabolism, Molecular neurodegeneration, NEOMED College of Pharmacy, Protein Kinases/*metabolism, Ransohoff Richard M, Receptors, Signal Transduction/physiology, tau Proteins/*metabolism, Tauopathies/metabolism/*pathology, Transgenic, Wilson Gina, Xu Guixiang
Turnover of histones and histone variants in postnatal rat brain: effects of alcohol exposure.
Tags: *2H2O-labeling, *Brain, *Genetic Variation, *Histone, *Mass spectrometry, *Post-translational modifications, *Postnatal alcohol exposure, *Turnover, 2017, Acetylation, Animal, Animals, Cell Proliferation, Clinical epigenetics, Department of Pharmaceutical Sciences, Disease Models, DNA Damage, Epigenesis, Female, Fetal Alcohol Spectrum Disorders/genetics/*metabolism, Genetic, Histones/*genetics/*metabolism, Humans, Kasumov Takhar, Li Ling, NEOMED College of Pharmacy, Post-Translational, Pregnancy, Previs Stephen, Protein Processing, Proteomics/*methods, Rachdaoui Nadia, Rats, Sarkar Dipak, Sprague-Dawley, Willard Belinda
Valproate increases dopamine transporter expression through histone acetylation and enhanced promoter binding of Nurr1.
Tags: 2017, Acetylation/drug effects, Animals, Butyrates/pharmacology, Cell Line, Cell Survival/drug effects, Department of Pharmaceutical Sciences, Dopamine Plasma Membrane Transport Proteins/*metabolism, Dopamine transporter, Dopaminergic Neurons/cytology/drug effects/metabolism, Dose-Response Relationship, Drug, Eid Aseel, Epigenesis, Epigenetics, Genetic, Genetic/drug effects, Green Ashley L, Group A, Guo Grace L, HDAC, Histone deacetylase, Histone Deacetylase Inhibitors/*pharmacology, Histone Deacetylases/metabolism, Histones/*drug effects/metabolism, Homeodomain Proteins/metabolism, Hydroxamic Acids/pharmacology, Member 2/*metabolism, Messenger/metabolism, NEOMED College of Pharmacy, Neuropharmacology, Nuclear Receptor Subfamily 4, Nurr1, Pitx3, Promoter Regions, Rats, Richardson Jason R, RNA, Transcription Factors/metabolism, Valproate, Valproic Acid/*pharmacology, Zarbl Helmut, Zhan Le