Browse Items (287 total)
- Tags: 2013
In situ simulation to assess workplace attitudes and effectiveness in a new facility.
Tags: *Attitude of Health Personnel, *Patient Simulation, 2013, Adult, Ahmed Rami A, Emergency Service, Frey Jennifer A, Gardner Aimee King, George Richard L, Hospital/*organization & administration, Hospitals, Humans, Inservice Training/methods, Patient Care Team/*organization & administration, Patient Safety/*standards, Self Efficacy, Simulation in healthcare : journal of the Society for Simulation in Healthcare, Teaching/organization & administration, Trauma Centers/*organization & administration, Workforce
Unique N-linked glycosylation of CasBrE Env influences its stability, processing, and viral infectivity but not its neurotoxicity.
Tags: *Protein Processing, 2013, Animals, Canavan Disease/pathology/virology, Department of Integrative Medical Sciences, DNA Mutational Analysis, env/genetics/*metabolism, Gene Products, Glycosylation, Journal of virology, Leukemia Virus, Lynch William P, Mice, Murine/genetics/*pathogenicity/*physiology, NEOMED College of Medicine, Post-Translational, Renszel Krystal M, Traister Russell S, Virulence, Virus Replication
Estrogen-related receptor gamma controls hepatic CB1 receptor-mediated CYP2E1 expression and oxidative liver injury by alcohol.
Tags: 2013, Alcohol-Induced Injury, Alcoholic Liver Disease, Alcoholic/genetics/*metabolism/prevention & control, Animals, Cannabinoid, CB1/*physiology, Chiang John Y L, Choi Hueng-Sik, Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 CYP2E1/genetics/*metabolism, Department of Integrative Medical Sciences, Enzyme Inhibitors/pharmacology/therapeutic use, Enzymologic/drug effects/physiology, Estrogen/deficiency/genetics/*physiology, Ethanol/pharmacology, Gene Expression Profiling/methods, Gene Expression Regulation, Gene Regulation, Genetic/physiology, Gut, Inbred C57BL, Jang Hyun-Hee, Jeong Won-Il, Kim Don-Kyu, Kim Jung Ran, Kim Yong-Hoon, Knockout, Koh Minseob, Koo Seung-Hoi, Lee Chul-Ho, Liver, Liver Diseases, Liver Metabolism, Liver/metabolism, Male, Mice, NEOMED College of Medicine, Oxidation-Reduction, Oxidative Stress/physiology, Park Jinyoung, Park Seung Bum, Park Tae-Sik, Receptor, Receptors, Signal Transduction/drug effects/physiology, Tamoxifen/analogs & derivatives/pharmacology/therapeutic use, Transcription, Yun Chul-Ho
The role of mitochondrial bioenergetics and reactive oxygen species in coronary collateral growth.
Tags: *Collateral Circulation, *Coronary Circulation, *Energy Metabolism, *Neovascularization, 2013, American journal of physiology. Heart and circulatory physiology, angiogenesis, Animals, Arteriogenesis, Chilian William M, Coronary Vessels/metabolism, Department of Integrative Medical Sciences, Di Vincenzo Lola, Hardwick James P, Humans, Logan Suzanna, Mitochondria, Mitochondrial Proteins/metabolism, Muscle, Muscle/*metabolism, Myocytes, NEOMED College of Medicine, Ohanyan Vahagn, Oxidative Stress, Phenotype, Physiologic, Pung Yuh Fen, Reactive Oxygen Species/*metabolism, Redox-dependent signaling, Sam Wai Johnn, Signal Transduction, Smooth, Smooth Muscle/*metabolism, Vascular/*metabolism, Yin Liya
Pomegranate Bioactive Constituents Suppress Cell Proliferation and Induce Apoptosis in an Experimental Model of Hepatocellular Carcinoma: Role of Wnt/ beta -Catenin Signaling Pathway.
A gradient boosting algorithm for survival analysis via direct optimization of concordance index.
Tags: *Survival Analysis, 2013, Algorithms, Artificial Intelligence, Breast Neoplasms/*epidemiology/*mortality, Chen Yifei, Clinical, Computational and mathematical methods in medicine, Databases, Decision Support Systems, Factual, Female, Humans, Internet, Jia Zhenyu, Mercola Dan, Models, Prognosis, Proportional Hazards Models, Software, Theoretical, Xie Xiaohui
Critical assessment of implantable drug delivery devices in glaucoma management.
Mitochondrial oxidative stress corrupts coronary collateral growth by activating adenosine monophosphate activated kinase-alpha signaling.
Tags: 2013, AMP-Activated Protein Kinases/*metabolism, Animal, Animals, Arteriosclerosis, thrombosis, and vascular biology, Body Weight/physiology, Cells, Chen Chwen-Lih, Chen Yeong-Renn, Chilian William M, Collateral Circulation, Coronary Circulation, Coronary Vessels/cytology/*enzymology, Cultured, Department of Integrative Medical Sciences, Disease Models, Dyck Jason R B, Endothelial Cells/cytology/*enzymology, Enrick Molly, Hardwick James P, Humans, Inbred WKY, Ischemia/metabolism/pathology, Kolz Christopher, Mitochondria, Mitochondria/drug effects/*metabolism, Myocardium/enzymology/pathology, NEOMED College of Medicine, Oxidative Stress/*physiology, Pung Yuh Fen, Rats, reactive oxygen species, Rotenone/pharmacology, Sam Wai Johnn, Signal Transduction/*physiology, Stevanov Kelly, Thakker Prashanth, TOR Serine-Threonine Kinases/metabolism, Uncoupling Agents/pharmacology, Yin Liya
An open-label dose escalation study to evaluate the safety of administration of nonviral stromal cell-derived factor-1 plasmid to treat symptomatic ischemic heart failure.
Tags: *Plasmids, 2013, Aged, Aras Rahul, Brain/blood, Chemokine CXCL12/*genetics/metabolism, Circulation research, Clemens Ruth, Cohort Studies, Dose-Response Relationship, Drug, Echocardiography, Exercise Tolerance, Farr Maryjane, Female, Follow-Up Studies, Genetic Therapy/*adverse effects/*methods, Heart Failure/metabolism/pathology/*therapy, Humans, Losordo Douglas W, Male, Mendelsohn Farrell O, Middle Aged, Myocardium/metabolism/pathology, Natriuretic Peptide, Pastore Joseph, Penn Marc S, Peptide Fragments/blood, Positron-Emission Tomography, Quality of Life, Rouy Didier, Schaer Gary L, Sherman Warren, Treatment Outcome
Antitumor efficacy and tolerability of systemically administered gallium acetylacetonate-loaded gelucire-stabilized nanoparticles.
Tags: *Lethal Dose 50, 2013, Adenocarcinoma/*drug therapy/pathology, Animals, Antineoplastic Agents/administration & dosage/pharmacokinetics/toxicity, Bi Lipeng, Cell Line, Department of Pharmaceutical Sciences, Dose-Response Relationship, Drug, Drug Stability, Drug Tolerance, Gallium/*administration & dosage/pharmacokinetics/*toxicity, Geldenhuys Werner J, Humans, Journal of biomedical nanotechnology, Metabolic Clearance Rate, Mice, Nanocapsules/*administration & dosage/chemistry/*toxicity, NEOMED College of Pharmacy, Nude, Organ Specificity, Oyewumi Moses O, Tissue Distribution, Treatment Outcome, Triglycerides/chemistry, Tumor, Wehrung Daniel
Disentangling consumer and provider predictors of advance care planning.
Tags: *Advance Care Planning, *Long-Term Care, 2013, Adult, advance care planning, Age Factors, Allen Kyle R, area agencies on aging, Attitude of Health Personnel, Baughman Kristin R, care management, Caregivers, community-based care, Conceptual Framework, Consumers, Data Analysis Software, Department of Family & Community Medicine, Discussion, Factorial Design, factorial surveys, Female, Hazelett Susan, Human, Humans, Judgment, Long Term Care, Long-Term Care, Ludwick Ruth, Merolla David, Middle Age, Multivariate Analysis, NEOMED College of Medicine, Palmisano Barbara, Quasi-Experimental Studies, Questionnaires, Random Sample, registered nurses, Sanders Margaret, social workers, Surveys, Surveys and Questionnaires, The American journal of hospice & palliative care, Vignettes
Bone marrow SSEA1+ cells support the myocardium in cardiac pressure overload.
Tags: *Bone Marrow Transplantation, 2013, Animals, Bone Marrow Cells/cytology/*metabolism, Cardiac/cytology/metabolism, Cell Tracking, Department of Integrative Medical Sciences, Dong Feng, Finan Amanda, Kiedrowski Matthew, Lewis X Antigen/*metabolism, Male, Mesenchymal Stem Cells/cytology/metabolism, Mice, Myocardium/cytology/*metabolism/pathology, Myocytes, NEOMED College of Medicine, Penn Marc S, PloS one, Sopko Nikolai, Turturice Ben, Ventricular Remodeling
The power of the claw.
Designing drugs with multi-target activity: the next step in the treatment of neurodegenerative disorders.
Activation of synaptic group II metabotropic glutamate receptors induces long-term depression at GABAergic synapses in CNS neurons.
Tags: 2013, Amino Acids/pharmacology, Animals, Chick Embryo, Cochlear Nucleus/drug effects/metabolism, Curry Rebecca J, Cyclopropanes/pharmacology, Department of Anatomy & Neurobiology, Dinh Emilie Hoang, Excitatory Amino Acid Agonists/pharmacology, Excitatory Amino Acid Antagonists/pharmacology, Excitatory Postsynaptic Potentials/drug effects/physiology, GABAergic Neurons/drug effects/*metabolism, Glycine/analogs & derivatives/pharmacology, Hamlet William R, Inhibitory Postsynaptic Potentials/drug effects/physiology, Liu Yu-Wei, Long-Term Synaptic Depression/drug effects/*physiology, Lu Yong, Metabotropic Glutamate/agonists/antagonists & inhibitors/*metabolism, NEOMED College of Medicine, Neural Inhibition/drug effects/physiology, Receptors, Shi Wei, Synapses/drug effects/*metabolism, Synaptic Transmission/drug effects/*physiology, Tang Zheng-Quan, The Journal of neuroscience : the official journal of the Society for Neuroscience, Xanthenes/pharmacology
Coding the meaning of sounds: contextual modulation of auditory responses in the basolateral amygdala.
Tags: 2013, Acoustic Stimulation/*methods, Action Potentials/*physiology, Amygdala/*physiology, Animal/*physiology, Animals, Auditory Perception/*physiology, Cats, College of Anatomy & Neurobiology, Department of Anatomy & Neurobiology, Female, Grimsley Jasmine M S, Hazlett Emily G, Inbred CBA, Male, Mice, NEOMED College of Medicine, The Journal of neuroscience : the official journal of the Society for Neuroscience, Vocalization, Wenstrup Jeffrey J
Safety and efficacy of cangrelor, an intravenous, short-acting platelet inhibitor in patients requiring coronary artery bypass surgery.
Tags: 2013, 80 and over, Adenosine Monophosphate/administration & dosage/*analogs & derivatives, Administration, Adult, Aged, Angiolillo Dominick J, Blood Transfusion/*statistics & numerical data, Brtko Miroslav, Cannon Louis A, Chandna Harish, Chronos Nicholas, Combination/statistics & numerical data, Coronary Artery Bypass/*statistics & numerical data, Dietrich Markus, Drug Therapy, Drug-Related Side Effects and Adverse Reactions/epidemiology, Dyke Cornelius M, Female, Firstenberg Michael S, Holmes David R, Humans, Hutyra Martin, Injections, Intravenous, Liu Tiepu, Male, Manoukian Steven V, Middle Aged, Montalescot Gilles, Oral, Placebo Effect, Platelet Aggregation Inhibitors/administration & dosage, Postoperative Hemorrhage/*epidemiology/*prevention & control, Prats Jayne, Premedication/*statistics & numerical data, Prevalence, Price Matthew, Purinergic P2Y Receptor Antagonists/administration & dosage, Pyridines/*administration & dosage, Ramaiahm Chandrashekar, Risk Assessment, The heart surgery forum, Todd Meredith, Topo Eric J, Treatment Outcome, Tummala Pradyumna, United States/epidemiology, Voeltz Michele, Welsby Ian
Evaluation and use of a rapid Staphylococcus aureus assay by an antimicrobial stewardship program.
Tags: 2013, Affinity, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, Anti-Bacterial Agents/administration & dosage/*pharmacology, Bacteriological Techniques, Barrett Heather L, Biological Assay – Methods, Cell Culture Techniques, Chromatography, Community, Department of Internal Medicine, DiPersio Joseph R, False Negative Reactions, File Thomas M Jr, Funding Source, Hospitals, Human, Humans, Methicillin-Resistant Staphylococcus Aureus – Analysis, Methicillin-Resistant Staphylococcus aureus/*isolation & purification, Microbial Sensitivity Tests, NEOMED College of Medicine, Observational Methods, Pasquale Timothy R, Prospective Studies, Sensitivity and Specificity, Staphylococcal Infections/*diagnosis/microbiology, Staphylococcus aureus/*isolation & purification, Time Factors, Trienski Tamara L
Minocycline-induced hyperpigmentation: comparison of 3 Q-switched lasers to reverse its effects.
Tags: 2013, Ahmad Asad, antibiotic, Brodell Robert T, Clinical, cosmetic and investigational dermatology, Department of Internal Medicine, discoloration, inflammatory disease, Iyer Karthik, Lloyd Jenifer R, NEOMED College of Medicine, Nisar Mahrukh S, Rheumatoid arthritis, Shin Thuzar M, tetracycline, wavelength
Over diagnosis of chronic obstructive pulmonary disease in an underserved patient population.
Tags: *Diagnostic Errors, *Medically Underserved Area, *Spirometry, *Vulnerable Populations, 2013, Administration, Adult, Awad Magdi H, Bronchodilator Agents/administration & dosage, Cholinergic Antagonists/administration & dosage, chronic obstructive pulmonary disease, Chronic Obstructive/*diagnosis/drug therapy/epidemiology/physiopathology, COPD, Dai Allen, Department of Pharmacy Practice, Female, Forced Expiratory Volume, Gemmel David J, Ghattas Christian, Humans, Inhalation, International journal of chronic obstructive pulmonary disease, Lung/drug effects/*physiopathology, Male, Medically Uninsured, Middle Aged, misdiagnosis, NEOMED College of Pharmacy, Ohio/epidemiology, over diagnosis, Predictive Value of Tests, Prevalence, Pulmonary Disease, Retrospective Studies, Risk Factors, Smoking/adverse effects/epidemiology, Spirometry, underserved, uninsured, Vital Capacity
Rationally designed multi-targeted agents against neurodegenerative diseases.
Tags: 2013, Amyloid beta-Peptides/antagonists & inhibitors, Animals, Calcium Channel Blockers/chemistry/pharmacology, Cholinesterase Inhibitors/chemistry/pharmacology, Current medicinal chemistry, Drug Discovery/*methods, Geldenhuys W J, Humans, Molecular Targeted Therapy/methods, Monoamine Oxidase Inhibitors/chemistry/pharmacology, N-Methyl-D-Aspartate/antagonists & inhibitors, Neurodegenerative Diseases/*drug therapy/metabolism, Receptors, Signal Transduction/drug effects, Van der Schyf C J
Nuclear receptors in bile acid metabolism.
Tags: 2013, Animals, Bile Acids and Salts/*metabolism, Biological Transport, Chiang John Y L, Cytoplasmic and Nuclear/genetics/*metabolism, Department of Integrative Medical Sciences, Drug metabolism reviews, Humans, Inactivation, Li Tiangang, Metabolic, NEOMED College of Medicine, Receptors, Xenobiotics/metabolism/pharmacology
Thermoreversible gel for delivery of activin receptor-like kinase 5 inhibitor
Tags: *Drug Delivery Systems, 2013, Animal, Animals, Benzodioxoles/*administration & dosage/pharmacokinetics/toxicity, Bhatia Deepak, Body Temperature, Delayed-Action Preparations, Disease Models, Drug Carriers/chemistry/toxicity, Fibroblasts/drug effects/metabolism, Filtering Surgery/*methods, Geldenhuys Werner, Gels, Glaucoma/*surgery, Imidazoles/*administration & dosage/pharmacokinetics/toxicity, Miladore Nicholas, Nakamura Hiroshi, Pharmaceutical development and technology, Poloxamer/chemistry/toxicity, Protein-Serine-Threonine Kinases/antagonists & inhibitors, Pyridines/*administration & dosage/pharmacokinetics/toxicity, Rabbits, Receptor, Receptors, Sutariya Vijaykumar, Temperature, Time Factors, Transforming Growth Factor beta/antagonists & inhibitors, Transforming Growth Factor-beta Type I, Viscosity, Wehrung Daniel
Antitumor activities of extracts from selected desert plants against HepG2 human hepatocellular carcinoma cells.
Tags: 2013, Aerial, Antineoplastic Agents, Bishayee Anupam, Carcinoma, Desert Climate, Dose-Response Relationship, Drug, Harlev Eli, Hep G2 Cells, Hepatocellular/*drug therapy/pathology, Humans, Inhibitory Concentration 50, Liver Neoplasms/*drug therapy/pathology, Mandal Animesh, Medicinal/chemistry, Nevo Eviatar, Pharmaceutical biology, Phytogenic/administration & dosage/*pharmacology, Plant Components, Plant Extracts/administration & dosage/*pharmacology, Plants, Tetrazolium Salts/chemistry, Thiazoles/chemistry, Thoppil Roslin J, Time Factors
Novel beta-lactamase inhibitors: a therapeutic hope against the scourge of multidrug resistance.
Ultrastructural examination of the corticocollicular pathway in the guinea pig: a study using electron microscopy, neural tracers, and GABA immunocytochemistry.
Tags: 2013, auditory cortex, bouton classification, corticofugal pathways, Department of Anatomy & Neurobiology, Frontiers in neuroanatomy, inferior colliculi, Killius Jeanette, Mellott Jeffrey G, Nakamoto Kyle T, NEOMED College of Medicine, Schofield Brett R, Sowick Colleen S, Storey-Workley Megan E, synaptic targets, ultrastructural variations
Functional architecture of the inferior colliculus revealed with voltage-sensitive dyes.
Tags: 2013, Acoustic Stimulation/methods, Animals, Auditory Pathways/chemistry/cytology/physiology, Chandrasekaran Lakshmi, Fluorescent Dyes/*analysis, Frontiers in neural circuits, Inbred CBA, Inferior Colliculi/*chemistry/*cytology/physiology, laminar organization, local circuits, Long-Evans, Mice, microcircuits, Nerve Net/*chemistry/*cytology/physiology, population coding, post-inhibitory rebound, Rats, Sivaramakrishnan Shobhana, Voltage-Sensitive Dye Imaging/*methods, Xiao Ying
Midbrain local circuits shape sound intensity codes.
Tags: 2013, Acoustic Stimulation, Animals, Auditory Pathways/*physiology, Auditory Perception/*physiology, Auditory Threshold/physiology, Frontiers in neural circuits, Grimsley Calum Alex, high divalents, Inferior Colliculi/*physiology, inferior colliculus, local circuits, Mice, monosynaptic, Neural Inhibition/*physiology, Neurons/physiology, Sanchez Jason Tait, Sivaramakrishnan Shobhana, sound intensity
High concentrations of divalent cations isolate monosynaptic inputs from local circuits in the auditory midbrain.
Tags: 2013, Acoustic Stimulation, Animals, Cations, Divalent/*pharmacology, first spike latency, Frontiers in neural circuits, Grimsley Calum Alex, high divalents, Inferior Colliculi/drug effects/*physiology, inferior colliculus, local circuits, Mice, monosynaptic, Neural Inhibition/drug effects/*physiology, Reaction Time/drug effects/physiology, Sanchez Jason Tait, Sivaramakrishnan Shobhana, Synapses/drug effects/*physiology
Albinism: particular attention to the ocular motor system.
Tags: 2013, Albinism, Eye Movements/physiology, Hertle Richard W, Humans, Middle East African journal of ophthalmology, Nystagmus, Ocular Motor System, Ocular/epidemiology/*physiopathology/therapy, Oculocutaneous/epidemiology/*physiopathology/therapy, Oculomotor Nerve/*physiopathology, Pathologic/epidemiology/*physiopathology/therapy, Visual Function
Hyperinsulinemia associated with acanthosis nigricans, finger pebbles, acrochordons, and the sign of Leser-Trelat.
Tags: 2013, Acanthosis Nigricans/diagnosis/etiology/metabolism, Al-Shoha Ahmad, Brodell Robert T, Department of Internal Medicine, Diabetes Mellitus, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, Humans, NEOMED College of Medicine, Receptors, Saraiya Ami, Skin Diseases/diagnosis/*etiology/metabolism, Somatomedin/metabolism, Type 2/*complications/metabolism
A TRP to cardiac fibroblast differentiation.
Tags: *Calcium Signaling, *Cell Differentiation, *Cell Transdifferentiation, *Mechanotransduction, *Wound Healing, 2013, Animals, Atrial Fibrillation/*metabolism, cardiac fibroblast, Cellular, Channels (Austin, Tex.), Department of Integrative Medical Sciences, differentiation, ECM stiffness, Female, Fibroblasts/*metabolism/*physiology, Humans, integrin, Male, mechanical signaling, Meszaros J Gary, myofibroblast, Myofibroblasts/*cytology/*metabolism, NEOMED College of Medicine, Paruchuri Sailaja, Rho/ROCK, Thodeti Charles K, TRPC Cation Channels/*metabolism, TRPM Cation Channels/*metabolism, TRPV Cation Channels/*metabolism, TRPV4
Fulminant Clostridium difficile infection: An association with prior appendectomy?
Two-trocar cholecystectomy by strategic laparoscopy for improved cosmesis (SLIC).
Tags: 2013, Adult, Body Mass Index, Bohon Ashley, Cholecystectomy, Dan Adrian G, Feasibility Studies, Female, Humans, JSLS : Journal of the Society of Laparoendoscopic Surgeons, Laparoscopic/*instrumentation/*methods, Middle Aged, Mirhaidari Shayda, Operative Time, Pozsgay Mark, Prospective Studies, Standerwick Andrew, Surgical Instruments, Young Adult, Zografakis John G