Browse Items · NEOMED Bibliography Database

A case of chronic paclitaxel administration in ovarian cancer

Background. Treatment with chemotherapeutic agents, after initial ovarian tumor debulking, and during recurrence, results in extended chemotherapy. When ovarian cancer recurs, chemotherapy is continued when patients respond to therapy. However, the…

A Case of Pancreatic Adenosquamous Carcinoma Obstructing the Common Bile and Pancreatic Ducts, Duodenum, and Gastric Outlet.

A Comparison of Quality-of-Life Domains and Clinical Factors in Ovarian Cancer Patients: A Gynecologic Oncology Group Study

Context. Women diagnosed with ovarian cancer are at risk for reduced quality of life (QOL). It is imperative to further define these declines to interpret treatment outcomes and design appropriate clinical interventions. Objectives. The primary…

A novel role of transforming growth factor beta1 in transcriptional repression of human cholesterol 7alpha-hydroxylase gene.

BACKGROUND & AIMS: Inhibition of cholesterol 7alpha-hydroxylase (CYP7A1) by bile acids and inflammatory cytokines provides an important mechanism to protect hepatocytes from bile acid toxicity during cholestasis. Transforming growth factor beta1…

A Simple and Effective Treatment for Ectopic Sebaceous Glands on the Areola

The authors have indicated no significant interest with commercial supporters.

Tags: 2010, bichloracetic acid, Brodell R T, Carcinoma, dermatologic surgery, Dermatology, fordyce spots, granules, Journal Article, mucosa, Surgery, therapy, Tulbert B

Acquired inhibitor to factor VIII in small cell lung cancer: a case report and review of the literature.

Acquired hemophilia (antibodies or inhibitors to factor VIII) is the most common acquired disease affecting clotting factors. It has been described in association with autoimmune disease, malignancy, dermatologic disorders, in the postpartum period,…

Tags: 2001, Ahmed F, Annals of hematology, Carcinoma, Crock R, Department of Internal Medicine, Factor VIII/*antagonists & inhibitors, Humans, Lara L, Lung Neoplasms/*chemistry, Male, Middle Aged, NEOMED College of Medicine, Rutecki G W, Shwaiki A, Small Cell/*chemistry, Whittier F C

Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy.

Tumor vessels are characterized by abnormal morphology and hyperpermeability that together cause inefficient delivery of chemotherapeutic agents. Although vascular endothelial growth factor has been established as a critical regulator of tumor…

Alternative medicine in gynecologic oncology: A case report.

A patient with Stage IIB squamous cell cancer of the cervix presented 10 days into her primary radiation therapy with neutropenic fever and diarrhea requiring hospitalization and delay in treatment. The patient's history revealed extensive use of…

Tags: *Complementary Therapies, 2000, Carcinoma, Diarrhea/*etiology, Female, Fever/*etiology, Gynecologic oncology, Hopkins M P, Hospitalization, Humans, Medical History Taking, Medicinal/*adverse effects, Middle Aged, Neutropenia/*etiology, Plants, Squamous Cell/drug therapy/*radiotherapy, Time Factors, Uterine Cervical Neoplasms/drug therapy/*radiotherapy, von Gruenigen V E

Angiogenesis in hepatocellular carcinoma: a potential target for chemoprevention and therapy.

Hepatocellular carcinoma (HCC) remains one of the most lethal cancers in the world. Since current treatment options including surgical resection and liver transplantation offer limited therapeutic benefits, there exists a need to evaluate novel…

Tags: 2012, Angiogenesis Inhibitors/*therapeutic use, Animals, Bishayee Anupam, Carcinoma, Current cancer drug targets, Darvesh Altaf S, Department of Pharmaceutical Sciences, Hepatocellular/blood supply/pathology/*prevention & control, Humans, Liver Neoplasms/blood supply/pathology/*prevention & control, NEOMED College of Pharmacy, Neovascularization, Pathologic/*prevention & control

Anthocyanin-rich black currant extract suppresses the growth of human hepatocellular carcinoma cells.

Dietary antioxidants, such as anthocyanins, are helpful in the prevention and control of various diseases by counteracting the imbalance of oxidative and antioxidative factors in the living systems. Black currant (Ribes nigrum L., Grossulariaceae) is…

Antitumor activities of extracts from selected desert plants against HepG2 human hepatocellular carcinoma cells.

CONTEXT: Phytochemicals are produced by desert plants to protect themselves against stressful environments. They have been shown to be useful in preventing and fighting adverse pathophysiological conditions and complex diseases, including cancer.…

Antitumor effect of novel silatranes on renal cell carcinoma in mice.

The effect of several novel silatrane derivatives on the growth of syngeneic renal cell carcinoma (RENCA) in BALB/c mice and the survival rate of the animals were evaluated. The RENCA-bearing animals were treated subcutaneously and weekly with either…

Tags: *Bridged Bicyclo Compounds, *Organosilicon Compounds, 1992, Animals, Anticancer research, Antineoplastic Agents/pharmacology/*therapeutic use, Bridged Bicyclo Compounds/pharmacology/*therapeutic use, Carcinoma, Female, Grna A, Heterocyclic, Hogan J, Inbred BALB C, Kidney Neoplasms/*drug therapy, Koo P H, Mice, Renal Cell/*drug therapy, Silicon/pharmacology/*therapeutic use, Structure-Activity Relationship

Assessment of Factors That Contribute to Decreased Quality of Life in Gynecologic Oncology Group Ovarian Cancer Trials

BACKGROUND: The objective of this study was to assess which quality-of-life (QOL) line items on the Functional Assessment of Cancer Therapy-Ovarian (FACT-O) were associated with low QOL in women who were receiving chemotherapy for ovarian cancer.…

Association of Thyroid, Breast and Renal Cell Cancer: A Population-based Study of the Prevalence of Second Malignancies

Analysis of the National Cancer Institute's Surveillance, Epidemiology, and End Results data has shown that the incidence of thyroid cancer is higher in patients with a preexisting malignancy and that the incidence of other malignancies is higher in…

Tags: 2013, Age, Annals of surgical oncology, Carcinoma, Eaton J L, Journal Article, McHenry C R, multiple primary breast, oncology, primary tumors, Risk, Surgery, united-states, Van Fossen V L, Wilhelm S M, Women

Barretts-esophagus - An Acquired Condition With Genetic Predisposition

Tags: 1993, Adenocarcinoma, American Journal of Gastroenterology, Carcinoma, columnar epithelium, Dysplasia, Fahmy N, Gastroenterology & Hepatology, King J F, spectrum

Basal cell adenocarcinoma of minor salivary glands.

Basal cell adenocarcinoma of minor salivary glands is a relatively rare slow-growing tumor with an infiltrating growth pattern. The infiltrating growth pattern and likelihood of vascular and perineural involvement distinguishes basal cell…

Tags: 2007, Adenocarcinoma/*diagnosis/radiotherapy/surgery, Adenoid Cystic/diagnosis, Adenoma/diagnosis, Archives of pathology & laboratory medicine, Carcinoma, Chang Yilan L, Combined Modality Therapy, Diagnosis, Differential, Farrell Tisha, Humans, Minor/*pathology/surgery, Salivary Gland Neoplasms/*diagnosis/radiotherapy/surgery, Salivary Glands, Squamous Cell/diagnosis

Basic transcription element binding protein (BTEB) transactivates the cholesterol 7 alpha-hydroxylase gene (CYP7A).

Cholesterol 7 alpha-hydroxylase catalyzes the first and rate-limiting step in the conversion of cholesterol to bile acids in the liver. Previously, we have identified two bile acid response elements located in nt -74 to -54 (BARE-I) and -148 to -118…

Bilateral adrenal metastases simulating abnormal renal uptake on a Ga-67 scan.

Tags: 2001, Adrenal Gland Neoplasms/pathology/*secondary, Carcinoma, Chalfant M L, Clinical nuclear medicine, Diagnosis, Differential, Female, Gallium Radioisotopes, Goyal M, Humans, Kidney/*diagnostic imaging, Konez O, Lung Neoplasms/*pathology, Middle Aged, Non-Small-Cell Lung/pathology/*secondary, Radionuclide Imaging, Radiopharmaceuticals

Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7alpha-hydroxylase gene expression.

UNLABELLED: Mouse fibroblast growth factor 15 (FGF15) and human ortholog FGF19 have been identified as the bile acid-induced intestinal factors that mediate bile acid feedback inhibition of cholesterol 7alpha-hydroxylase gene (C YP7A1) transcription…

Tags: 2009, Butadienes/pharmacology, Carcinoma, Cell Line, Chenodeoxycholic Acid/*pharmacology, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*biosynthesis, Cytoplasmic and Nuclear/metabolism/physiology, Department of Integrative Medical Sciences, DNA-Binding Proteins/metabolism, Fibroblast Growth Factor, Fibroblast Growth Factors/drug effects/*physiology, Gene Expression/drug effects, Hepatocellular/metabolism, Hepatocytes/metabolism, Hepatology (Baltimore, Md.), Humans, Isoxazoles/pharmacology, Li Tiangang, Mitogen-Activated Protein Kinase 1/metabolism, Mitogen-Activated Protein Kinase 3/metabolism, NEOMED College of Medicine, Nitriles/pharmacology, Owsley Erika, Receptor, Receptors, Signal Transduction/drug effects, Song Kwang-Hoon, Strom Stephen, Transcription Factors/metabolism, Tumor, Type 4/antagonists & inhibitors

Black currant anthocyanins abrogate oxidative stress through Nrf2- mediated antioxidant mechanisms in a rat model of hepatocellular carcinoma.

Hepatocellular carcinoma (HCC), considered to be one of the most lethal cancers with almost \textgreater 1 million deaths reported annually worldwide, remains a devastating disease with no known effective cure. Hence, chemopreventive strategies come…

Tags: *Phytotherapy, 2012, Alkylating Agents/toxicity, Animals, Anthocyanins/*therapeutic use, Antioxidants/therapeutic use, Barnes Kendra F, Bhatia Deepak, Bishayee Anupam, Blotting, Carcinoma, Current cancer drug targets, Darvesh Altaf S, Department of Pharmaceutical Sciences, Diet, Diethylnitrosamine/toxicity, Experimental/chemically induced/metabolism/*prevention & control, Glutathione Transferase, Haznagy-Radnai Erzsebet, Hepatocellular/chemically induced/metabolism/*prevention & control, Hohmann Judit, Immunoenzyme Techniques, Lipid Peroxidation/drug effects, Liver Neoplasms, Male, Messenger/genetics, NEOMED College of Pharmacy, NF-E2-Related Factor 2/genetics/*metabolism, Nitric Oxide Synthase Type II/genetics/metabolism, Oxidative Stress/*drug effects, Rats, Real-Time Polymerase Chain Reaction, Reverse Transcriptase Polymerase Chain Reaction, Ribes/*chemistry, RNA, Signal Transduction, Sprague-Dawley, Thoppil Roslin J, Tyrosine/analogs & derivatives/metabolism, Western

Canertinib induces ototoxicity in three preclinical models.

Neuregulin-1 (NRG1) ligand and its epidermal growth factor receptor (EGFR)/ERBB family regulate normal cellular proliferation and differentiation in many tissues including the cochlea. Aberrant NRG1 and ERBB signaling cause significant hearing…

Chemopreventive and therapeutic potential of tea polyphenols in hepatocellular cancer.

The prophylactic and therapeutic properties of tea have been attributed to green tea catechins and black tea theaflavins besides several other polyphenolic compounds. Tea polyphenols possess potent antioxidant and antiinflammatory properties and…

Chemopreventive doses of resveratrol do not produce cardiotoxicity in a rodent model of hepatocellular carcinoma.

Hepatocellular carcinoma (HCC), one of the most lethal cancers, results in more than one million fatalities worldwide every year. In view of the limited therapeutic alternatives and poor prognosis of liver cancer, preventive control approaches,…

Tags: *Chemoprevention, 2011, Analysis of Variance, Animal, Animal Studies, Animal/drug effects, Animals, Antioxidants, Behavior, Bishayee Anupam, Blotting, Booth Tristan D, Carcinoma, Cardiotoxicity, Cardiotoxins/*toxicity, Chemoprevention, Data Analysis Software, Department of Integrative Medical Sciences, Descriptive Statistics, Disease Models, Doppler, Dose-Response Relationship, Drug, Echocardiography, Feeding Behavior/drug effects, Female, Fisher's Exact Test, Funding Source, Heart – Drug Effects, Heart/drug effects/physiopathology, Hepatocellular – Prevention and Control, Hepatocellular/*drug therapy/pathology/physiopathology, Hepatocytes/drug effects/pathology, Hodnichak Cheryl M, Humans, Investigational new drugs, Liver Neoplasms/*drug therapy/pathology/physiopathology, Liver/drug effects/pathology/physiopathology, Luther Daniel J, Meszaros J Gary, NEOMED College of Medicine, Ohanyan Vahagn, Polyphenols – Therapeutic Use, Rats, Resveratrol, Shamhart Patricia E, Sisakian Hamayak, Sprague-Dawley, Stilbenes/*therapeutic use, Systole/drug effects, Western

CLEAR-CELL ADENOCARCINOMA ARISING FROM A URETHRAL DIVERTICULUM

Carcinoma of the urethra is rare with only about 1,500 cases in the literature. Even more rare is carcinoma arising from a urethral diverticulum with about 100 cases reported to date. We report a case of clear cell adenocarcinoma arising from a…

Tags: 1995, Adenocarcinoma, Carcinoma, diverticulum, Journal Article, Journal of Urology, Rich R R, Seballos R M, urethra, Urology & Nephrology

Clinical disease course during the last year in ovarian cancer

Objective(s). The objective was to determine whether there were changes in the pattern and nature of hospitalizations during the last year that could be used in the assessment of whether chemotherapy should be continued. Methods. Retrospective data…

Complete remission in a patient with metastatic mixed adenocarcinoma/extrapulmonary small cell carcinoma of the prostate.

Approximately 10% of all extra-pulmonary small cell carcinoma (EPSCC) arises in the prostate either as de novo mixed adenocarcinoma with small cell components or a pure small cell carcinoma. Extensive disease carries a median survival of about 10…

Tags: 2011, Adenocarcinoma/diagnosis/*secondary, Androgen Antagonists/therapeutic use, Bone Neoplasms/*drug therapy/*secondary, Brammer Jonathan Edward, Carcinoma, Cisplatin/therapeutic use, Combined Modality Therapy, Etoposide/therapeutic use, Humans, International journal of clinical oncology, Lulla Premal, Lung Neoplasms/diagnosis/*secondary, Lynch Garrett Rush, Male, Middle Aged, Prostatic Neoplasms/*drug therapy/metabolism/*pathology, Remission Induction, Small Cell/diagnosis/*secondary

Contrast-enhanced ultrasound detection and treatment guidance in a renal transplant patient with renal cell carcinoma.

Contrast-enhanced ultrasonography (CEUS) is an imaging modality that shows promise in the detection and characterization of renal masses, as well as treatment through CEUS-guided percutaneous radiofrequency ablation. These techniques may be…

Correlation of menstrual cycle at time of breast cancer surgery to disease-free and overall survival

The timing of surgery during the menstrual cycle of premenopausal breast cancer patients was correlated with their disease-free survival (DFS) and overall survival (OS). The study included 150 premenopausal patients treated for breast cancer between…

Tags: 1997, Bourguet C C, Carcinoma, General & Internal Medicine, Journal Article, Kadivar T F, killer cell-activity, Mastectomy, operation, phase, premenopausal women, Prognosis, Receptor, Southern medical journal, stage, status, surgical cure, Vanek V W

Curcumin and liver cancer: a review.

Primary liver cancer, also known as hepatocellular carcinoma (HCC), is one of the most lethal cancers having worldwide prevalence. Although most HCC cases are reported in the developing countries of Asia and Africa, there has been an alarming…

Tags: 2012, Aggarwal Bharat B, Animals, Anti-Inflammatory Agents/therapeutic use, Anticarcinogenic Agents/*therapeutic use, Antineoplastic Agents, Antioxidants/therapeutic use, Bishayee Anupam, Carcinoma, Curcumin/*therapeutic use, Current pharmaceutical biotechnology, Darvesh Altaf S, Department of Pharmaceutical Sciences, Hepatocellular/*drug therapy/prevention & control, Humans, Liver Neoplasms/*drug therapy/prevention & control, NEOMED College of Pharmacy, Phytogenic/*therapeutic use

Deficiency of G-protein-coupled bile acid receptor Gpbar1 (TGR5) enhances chemically induced liver carcinogenesis.

UNLABELLED: Gpbar1 (TGR5), a membrane-bound bile acid receptor, is well known for its roles in regulation of energy homeostasis and glucose metabolism. TGR5 activation also inhibits nuclear factor kappaB (NF-kappaB)-mediated inflammation. Here we…

Development of bilateral lower extremity Marjolin ulcers after childhood burns.

Tags: 2008, American journal of orthopedics (Belle Mead, N.J.), Burns/*complications, Carcinoma, Humans, Male, Middle Aged, Scharschmidt Tom, Skin Neoplasms/*etiology/surgery, Skin Ulcer/*etiology/surgery, Squamous Cell/*etiology/surgery, Tank Jason, Time Factors, Weiner Scott D

Diagnosis at a glance.

Tags: 2003, Basal Cell – Diagnosis, Carcinoma, Emergency Medicine (00136654), Hemangioma – Diagnosis, Male, Matthews M, Middle Age, Mouth Neoplasms – Diagnosis, Park Y W, Wu YT

Diagnosis at a glance.

Tags: 2003, Carcinoma, Child, Cysts – Diagnosis – In Infancy and Childhood, Emergency Medicine (00136654), Male, Middle Age, Park Y W, Squamous Cell – Diagnosis, Tang T, Tongue Diseases – Diagnosis, Wu YT

Dietary Phytochemicals In The Chemoprevention And Treatment Of Hepatocellular Carcinoma: In Vivo Evidence, Molecular Targets, And Clinical Relevance

Hepatocellular carcinoma (HCC), one of the most common and lethal cancers, is a growing menace in modern society. Until recently, the majority of detected cases of liver cancer have been found in the developing nations of Asia and Africa; however,…

Differences in the integration pattern and episomal forms of human papillomavirus type 16 DNA found within an invasive cervical neoplasm and its metastasis.

Human papillomavirus (HPV) type 16 DNA was found in three separate neoplastic lesions within a female patient. The physical state of the viral DNA in each lesion was determined by two-dimensional agarose gel electrophoresis. The primary cervical…

Disseminated brown tumors from hyperparathyroidism masquerading as metastatic cancer: a complication of parathyroid carcinoma.

Osteitis fibrosa cystica (brown tumors) can be a skeletal manifestation of advanced hyperparathyroidism, including parathyroid cancer. Severe osteitis fibrosa cystica can mimic metastatic bone diseases especially in patients with a history of cancer.…

Tags: 2001, Carcinoma, Carcinoma/*complications, Diagnosis, Differential, Female, Gupta A, Horattas M C, Humans, Hyperparathyroidism/complications, Kidney Neoplasms/pathology, Middle Aged, Moattari A R, Osteitis Fibrosa Cystica/*diagnosis/*etiology, Parathyroid Neoplasms/*complications, Renal Cell/secondary, Shorten S D, The American surgeon

Evaluation Of Appropriate Short-term Mammographic Surveillance In Patients Who Undergo Breast-conserving Surgery (bcs)

Mammography is an important surveillance tool for detecting ipsilateral breast tumor recurrence (IBTR) after BCS. Although IBTR is rare in the first 2 years, various organizations have established protocols for postoperative mammographic…

Tags: 2012, Annals of surgical oncology, Cancer, Carcinoma, conservative surgery, Follow-up, Gunia S R, irradiation, Journal Article or Conference Abstract Publication, local recurrence, Lumpectomy, Mamounas E P, Merrigan T L, oncology, Poulton T B, radiation-therapy, Radiotherapy, stage-i, Surgery

Glycogen-rich malignant melanomas and glycogen-rich balloon cell malignant melanomas - Frequency and pattern of PAS positivity in primary and metastatic melanomas

Objective.-After identifying a metastatic glycogen-rich balloon cell malignant melanoma, originally thought to be a benign clear cell tumor of the lung, we investigated the extent of positive reactions, or "positivity," of malignant melanoma to…

Tags: 1998, Archives of pathology & laboratory medicine, Campbell T E, Carcinoma, Fatteh S M, Journal Article, Lung, Medical Laboratory Technology, Nowak M A, Pathology, Research & Experimental Medicine, soft parts, sugar tumor

Guidelines of care for the management of cutaneous squamous cell carcinoma

Cutaneous squamous cell carcinoma (cSCC) is the second most common form of human cancer and has an increasing annual incidence. Although most cSCC is cured with office-based therapy, advanced cSCC poses a significant risk for morbidity, impact on…

Tags: 2018, 5-year follow-up, Alam M, american joint committee, Armstrong A, Baum C, Begolka W S, Bichakjian C, Biopsy, Bordeaux J S, Boyer K, Brown M, Busam K J, Carcinoma, curettage, Department of Family & Community Medicine, Dermatology, Eisen D B, fresh tissue technique, Huang C, Iyengar V, Journal Article or Conference Abstract Publication, Journal of the American Academy of Dermatology, Kim J Y S, Kozlow J H, limited life expectancy, Lober C, lymph-node biopsy, Margolis D J, Messina J, Metastasis, Miller A, Miller S, Mittal B, mohs micrographic surgery, Mostow E, Mowad C, Moyer J, Nehal K, NEOMED College of Medicine, nonmelanoma skin-cancer, Olenecki T, organ transplant, Phototherapy, Radiotherapy, randomized controlled-trial, recipients, Rodgers P, Schmitt-Burr K, Sekulic A, squamous cell, Staging, Storrs P, Surgery, surveillance, Teng J, topical photodynamic therapy, topical therapy, Yu S

Browse Items (79 total)