Browse Items (41 total)
- Tags: Bishayee Anupam
Alteration of hepatic proinflammatory cytokines is involved in the resveratrol-mediated chemoprevention of chemically-induced hepatocarcinogenesis.
Tags: 2012, Animals, Anticarcinogenic Agents/pharmacology/*therapeutic use, Awale Prabha, Bhatia Deepak, Bishayee Anupam, Carroll Richard T, Current pharmaceutical biotechnology, Cytokines/genetics/*metabolism, Darvesh Altaf S, Department of Pharmaceutical Sciences, Diethylnitrosamine, Experimental/chemically induced/metabolism/*prevention & control, Female, Geldenhuys Werner J, Gene Expression Regulation/drug effects, Liver Neoplasms, Liver/drug effects/metabolism, Mbimba Thomas, Messenger/metabolism, NEOMED College of Pharmacy, Phenobarbital, Rats, Resveratrol, RNA, Sprague-Dawley, Stilbenes/pharmacology/*therapeutic use
Angiogenesis in hepatocellular carcinoma: a potential target for chemoprevention and therapy.
Tags: 2012, Angiogenesis Inhibitors/*therapeutic use, Animals, Bishayee Anupam, Carcinoma, Current cancer drug targets, Darvesh Altaf S, Department of Pharmaceutical Sciences, Hepatocellular/blood supply/pathology/*prevention & control, Humans, Liver Neoplasms/blood supply/pathology/*prevention & control, NEOMED College of Pharmacy, Neovascularization, Pathologic/*prevention & control
Anthocyanin-rich black currant (Ribes nigrum L.) extract affords chemoprevention against diethylnitrosamine-induced hepatocellular carcinogenesis in rats.
Tags: 2011, Animals, Anthocyanins/*therapeutic use, Anticarcinogenic Agents/therapeutic use, Apoptosis/drug effects, bcl-2-Associated X Protein/metabolism, Bishayee Anupam, Cell Proliferation/drug effects, Chemoprevention, Darvesh Altaf S, Department of Pharmaceutical Sciences, Diethylnitrosamine, Down-Regulation, Experimental/metabolism/pathology, Folkesson Hans G, Haznagy-Radnai Erzsebet, Hohmann Judit, Liver Neoplasms, Liver Neoplasms/chemically induced/*prevention & control, Liver/pathology, Male, Mbimba Thomas, NEOMED College of Pharmacy, Phenobarbital, Plant Extracts/*therapeutic use, Proliferating Cell Nuclear Antigen/metabolism, Proto-Oncogene Proteins c-bcl-2/metabolism, Rats, Ribes/chemistry, Sipos Peter, Sprague-Dawley, The Journal of nutritional biochemistry, Thoppil Roslin J, Up-Regulation
Anthocyanin-rich black currant extract suppresses the growth of human hepatocellular carcinoma cells.
Tags: *Phytotherapy, *Ribes/chemistry, 2010, Antineoplastic Agents, Antioxidants/*therapeutic use, Bhatia Deepak, Bishayee Anupam, Carcinoma, Cell Proliferation/drug effects, Darvesh Altaf S, Department of Pharmaceutical Sciences, Drug Evaluation, Fruit/chemistry, Haznagy-Radnai Erzsebet, Hep G2 Cells, Hepatocellular/*prevention & control, Hohmann Judit, Humans, Liver Neoplasms/*prevention & control, Mbimba Thomas, Morazzoni Paolo, Natural product communications, NEOMED College of Pharmacy, Phytogenic/analysis, Plant Extracts/pharmacology/therapeutic use, Preclinical, Sipos Peter
Anti-Inflammatory Mechanism Involved in Pomegranate-Mediated Prevention of Breast Cancer: the Role of NF-kappaB and Nrf2 Signaling Pathways.
Tags: 10-Dimethyl-1, 2-benzanthracene/toxicity, 2017, 9, Animal Studies, Animals, Anti-Inflammatory Agents/*pharmacology, anti-inflammatory effects, Anticarcinogenic Agents/pharmacology, Apoptosis/drug effects, Bhatia Deepak, Bishayee Anupam, Breast Neoplasms, breast tumor, Cell Transformation, Chemoprevention, COX-2, Cyclooxygenase 2/genetics/metabolism, DMBA, Dose-Response Relationship, Drug, Experimental/*prevention & control, Female, Gene Expression Regulation, HSP90, HSP90 Heat-Shock Proteins/genetics/metabolism, I-kappa B Kinase/genetics/metabolism, Inflammation Mediators, Mammary Neoplasms, Mandal Animesh, Neoplasms – Prevention and Control, Neoplastic, Neoplastic/drug effects, NF-E2-Related Factor 2/genetics/*metabolism, NF-kappa B/genetics/*metabolism, NF-kappaB, Nrf2, Nutrients, Physical Education and Training, Plant Preparations/*pharmacology, Pomegranate, Punica granatum, Punicaceae/*chemistry, Rats, Signal Transduction
Antitumor activities of extracts from selected desert plants against HepG2 human hepatocellular carcinoma cells.
Tags: 2013, Aerial, Antineoplastic Agents, Bishayee Anupam, Carcinoma, Desert Climate, Dose-Response Relationship, Drug, Harlev Eli, Hep G2 Cells, Hepatocellular/*drug therapy/pathology, Humans, Inhibitory Concentration 50, Liver Neoplasms/*drug therapy/pathology, Mandal Animesh, Medicinal/chemistry, Nevo Eviatar, Pharmaceutical biology, Phytogenic/administration & dosage/*pharmacology, Plant Components, Plant Extracts/administration & dosage/*pharmacology, Plants, Tetrazolium Salts/chemistry, Thiazoles/chemistry, Thoppil Roslin J, Time Factors
Black currant anthocyanins abrogate oxidative stress through Nrf2- mediated antioxidant mechanisms in a rat model of hepatocellular carcinoma.
Tags: *Phytotherapy, 2012, Alkylating Agents/toxicity, Animals, Anthocyanins/*therapeutic use, Antioxidants/therapeutic use, Barnes Kendra F, Bhatia Deepak, Bishayee Anupam, Blotting, Carcinoma, Current cancer drug targets, Darvesh Altaf S, Department of Pharmaceutical Sciences, Diet, Diethylnitrosamine/toxicity, Experimental/chemically induced/metabolism/*prevention & control, Glutathione Transferase, Haznagy-Radnai Erzsebet, Hepatocellular/chemically induced/metabolism/*prevention & control, Hohmann Judit, Immunoenzyme Techniques, Lipid Peroxidation/drug effects, Liver Neoplasms, Male, Messenger/genetics, NEOMED College of Pharmacy, NF-E2-Related Factor 2/genetics/*metabolism, Nitric Oxide Synthase Type II/genetics/metabolism, Oxidative Stress/*drug effects, Rats, Real-Time Polymerase Chain Reaction, Reverse Transcriptase Polymerase Chain Reaction, Ribes/*chemistry, RNA, Signal Transduction, Sprague-Dawley, Thoppil Roslin J, Tyrosine/analogs & derivatives/metabolism, Western
Brain-targeted delivery of Tempol-loaded nanoparticles for neurological disorders.
Tags: *Lactic Acid, *Polyglycolic Acid, 2010, Animals, Antibodies, Antioxidants/chemistry/*metabolism, Bhatia Deepak, Bhatia Ruchi, Bishayee Anupam, Blood-Brain Barrier/metabolism, Carroll Richard T, Cell Line, Cross-Linking Reagents/chemistry, Cyclic N-Oxides/chemistry/*metabolism, Delayed-Action Preparations, Free Radical Scavengers/chemistry/*metabolism, Geldenhuys Werner, Journal of drug targeting, Maleimides/chemistry, Miladore Nicholas, Monoclonal/chemistry/*metabolism, Nanoparticles, Particle Size, Polyethylene Glycols, Polylactic Acid-Polyglycolic Acid Copolymer, Rats, Spin Labels, Sutariya Vijaykumar, Transferrin/*immunology, Tumor
Cancer prevention and treatment with resveratrol: from rodent studies to clinical trials.
CArG-driven GADD45alpha activated by resveratrol inhibits lung cancer cells.
Chemopreventive and therapeutic potential of tea polyphenols in hepatocellular cancer.
Tags: *Anticarcinogenic Agents, 2013, Animal, Animals, Anti-Inflammatory Agents, Antioxidants, Biological Availability, Biological Markers, Bishayee Anupam, Carcinoma, Catechin/administration & dosage/analogs & derivatives, Chemoprevention, Darvesh Altaf S, Department of Pharmaceutical Sciences, Disease Models, Hepatocellular – Physiopathology, Hepatocellular – Prevention and Control, Hepatocellular – Therapy, Human, Humans, In Vitro Studies, In Vivo Studies, Liver Neoplasms/*drug therapy/*prevention & control, Mice, NEOMED College of Pharmacy, Neoplasms – Prevention and Control, nutrition, Nutrition and cancer, Outcomes (Health Care), Phenols – Therapeutic Use, Polyphenols/*administration & dosage/pharmacology, Tea – Therapeutic Use, Tea/*chemistry, Xenograft Model Antitumor Assays
Chemopreventive doses of resveratrol do not produce cardiotoxicity in a rodent model of hepatocellular carcinoma.
Tags: *Chemoprevention, 2011, Analysis of Variance, Animal, Animal Studies, Animal/drug effects, Animals, Antioxidants, Behavior, Bishayee Anupam, Blotting, Booth Tristan D, Carcinoma, Cardiotoxicity, Cardiotoxins/*toxicity, Chemoprevention, Data Analysis Software, Department of Integrative Medical Sciences, Descriptive Statistics, Disease Models, Doppler, Dose-Response Relationship, Drug, Echocardiography, Feeding Behavior/drug effects, Female, Fisher's Exact Test, Funding Source, Heart – Drug Effects, Heart/drug effects/physiopathology, Hepatocellular – Prevention and Control, Hepatocellular/*drug therapy/pathology/physiopathology, Hepatocytes/drug effects/pathology, Hodnichak Cheryl M, Humans, Investigational new drugs, Liver Neoplasms/*drug therapy/pathology/physiopathology, Liver/drug effects/pathology/physiopathology, Luther Daniel J, Meszaros J Gary, NEOMED College of Medicine, Ohanyan Vahagn, Polyphenols – Therapeutic Use, Rats, Resveratrol, Shamhart Patricia E, Sisakian Hamayak, Sprague-Dawley, Stilbenes/*therapeutic use, Systole/drug effects, Western
Curcumin and liver cancer: a review.
Tags: 2012, Aggarwal Bharat B, Animals, Anti-Inflammatory Agents/therapeutic use, Anticarcinogenic Agents/*therapeutic use, Antineoplastic Agents, Antioxidants/therapeutic use, Bishayee Anupam, Carcinoma, Curcumin/*therapeutic use, Current pharmaceutical biotechnology, Darvesh Altaf S, Department of Pharmaceutical Sciences, Hepatocellular/*drug therapy/prevention & control, Humans, Liver Neoplasms/*drug therapy/prevention & control, NEOMED College of Pharmacy, Phytogenic/*therapeutic use
Curcumin and neurodegenerative diseases: a perspective.
Tags: 2012, Animals, Bishayee Anupam, Carroll Richard T, Curcumin/adverse effects/pharmacokinetics/*pharmacology/*therapeutic use, Darvesh Altaf S, Department of Pharmaceutical Sciences, Drug Evaluation, Expert opinion on investigational drugs, Geldenhuys Werner J, Humans, NEOMED College of Pharmacy, Neurodegenerative Diseases/*drug therapy/metabolism, Neuroprotective Agents/adverse effects/pharmacokinetics/*pharmacology/*therapeutic use, Novotny Nicholas A, Oxidative Stress/drug effects, Preclinical, Van der Schyf Cornelis J
d -Limonene sensitizes docetaxel-induced cytotoxicity in human prostate cancer cells: Generation of reactive oxygen species and induction of apoptosis.
Health-promoting and disease-preventive potential of Trianthema portulacastrum Linn. (Gadabani) -An Indian medicinal and dietary plant.
Mechanism of Breast Cancer Preventive Action of Pomegranate: Disruption of Estrogen Receptor and Wnt/beta-Catenin Signaling Pathways.
Tags: 10-Dimethyl-1, 2-benzanthracene/pharmacology, 2015, 9, Animals, Anticarcinogenic Agents/*pharmacology, beta Catenin/*metabolism, beta-catenin, Bishayee Anupam, Breast Neoplasms/*drug therapy/metabolism, Cell Proliferation/drug effects, Cell Transformation, Chemoprevention/methods, Cyclin D1, DMBA, Down-Regulation/drug effects, Estrogen Receptor alpha/metabolism, estrogen receptors, Estrogen/*metabolism, Female, mammary tumorigenesis, Mandal Animesh, Molecules (Basel, Switzerland), Neoplastic/drug effects/metabolism, pomegranate (Punica granatum L.), Punicaceae/*chemistry, Rats, Receptors, Sprague-Dawley, Wnt Proteins/*metabolism, Wnt Signaling Pathway/*drug effects
Modulation of angiogenesis by dietary phytoconstituents in the prevention and intervention of breast cancer.
Tags: *Diet, 2012, Anticarcinogenic Agents/*chemistry/*pharmacology, Bishayee Anupam, Breast Neoplasms/*blood supply/*prevention & control, Female, Gopalan Ashwin, Humans, Malus/chemistry, Molecular nutrition & food research, Neovascularization, Pathologic/metabolism/prevention & control, Petit Danielle M, Reuben Sharon C
Natural products of dietary origin as lead compounds in virtual screening and drug design.
Tags: *Biological Products/pharmacology, *Drug Design, 2012, Animals, Bishayee Anupam, Caffeine/pharmacology, Carroll Richard T, Curcumin/pharmacology, Current pharmaceutical biotechnology, Darvesh Altaf S, Department of Pharmaceutical Sciences, Diet, Geldenhuys Werner J, Genistein/pharmacology, Humans, NEOMED College of Pharmacy, Resveratrol, Stilbenes/pharmacology
Oleanane triterpenoids in the prevention and therapy of breast cancer: current evidence and future perspectives.
Oxidative stress and Alzheimer's disease: dietary polyphenols as potential therapeutic agents.
Tags: 2010, Alzheimer Disease/*physiopathology/*therapy, Animals, Antioxidants/*administration & dosage/chemistry/pharmacology, Bishayee Anupam, Carroll Richard T, Darvesh Altaf S, Department of Pharmaceutical Sciences, Expert review of neurotherapeutics, Flavonoids/*administration & dosage/chemistry/pharmacology, Geldenhuys Werner J, Humans, Mitochondria/drug effects/physiology, NEOMED College of Pharmacy, Neurodegenerative Diseases/physiopathology, Oxidative Stress/drug effects/*physiology, Phenols/*administration & dosage/chemistry/pharmacology, Polyphenols, Van der Schyf Cornelis J
Pomegranate Bioactive Constituents Suppress Cell Proliferation and Induce Apoptosis in an Experimental Model of Hepatocellular Carcinoma: Role of Wnt/ beta -Catenin Signaling Pathway.
Pomegranate Bioactive Constituents Suppress Cell Proliferation and Induce Apoptosis in an Experimental Model of Hepatocellular Carcinoma: Role of Wnt/β-Catenin Signaling Pathway.
Tags: 2013, Animal Studies, Apoptosis, Bhatia Deepak, Bishayee Anupam, Blotting, Carcinoma, Darvesh Altaf S, Department of Pharmaceutical Sciences, Evidence-based Complementary & Alternative Medicine (eCAM), Experimental Studies, Gene Expression, Hepatocellular, Immunohistochemistry, In Vivo Studies, Mandal Animesh, NEOMED College of Pharmacy, One-Way Analysis of Variance, Pomegranate, Post Hoc Analysis, Protocols, Rats, Samtani Karishma A, STRUCTURAL equation modeling, Thoppil Roslin J, Western
Pomegranate exerts chemoprevention of experimentally induced mammary tumorigenesis by suppression of cell proliferation and induction of apoptosis.
Tags: *Punicaceae/chemistry, 10-Dimethyl-1, 2-benzanthracene, 2016, 9, Animal Studies, Animals, Anticarcinogenic Agents/*therapeutic use, Apoptosis, Apoptosis/*drug effects, Bhatia Deepak, Bhattacharyya Piyali, Bishayee Anupam, Breast Neoplasms – Mortality, Breast Neoplasms – Prevention and Control, Breast Neoplasms – Risk Factors, Cell Physiology, Cell Proliferation/*drug effects, Diet – Evaluation, Experimental/pathology/*prevention & control, Female, Funding Source, Gene Expression Regulation, Genes, Human, Immunohistochemistry, Mammary Neoplasms, Mandal Animesh, Mutation, National Institutes of Health (U.S.), Neoplasms – Prevention and Control, Nutrition and cancer, Phytotherapy, Pomegranate, Proto-Oncogene Proteins c-bcl-2/analysis, Rats, Sprague-Dawley, Tamoxifen, United States
Pomegranate-mediated chemoprevention of experimental hepatocarcinogenesis involves Nrf2-regulated antioxidant mechanisms.
Tags: *Phytotherapy, 2011, Alkylating Agents/toxicity, Animals, Antioxidants/*therapeutic use, Bhatia Deepak, Bishayee Anupam, Blotting, Carcinogenesis, Carcinoma, Darvesh Altaf S, Department of Pharmaceutical Sciences, Diethylnitrosamine/toxicity, Experimental/chemically induced/*drug therapy/metabolism, GA-Binding Protein Transcription Factor/*metabolism, gamma-Glutamyltransferase/metabolism, Hepatocellular/chemically induced/*drug therapy/metabolism, Immunoenzyme Techniques, Lansky Ephraim P, Lipid Peroxidation/drug effects, Liver Neoplasms, Male, NEOMED College of Pharmacy, Nevo Eviatar, Oxidative Stress, Plant Extracts/*therapeutic use, Punicaceae/*chemistry, Rats, Sprague-Dawley, Thoppil Roslin J, Western
Potential Benefits of Edible Berries in the Management of Aerodigestive and Gastrointestinal Tract Cancers: Preclinical and Clinical Evidence.
Tags: 2016, aerodigestive and gastrointestinal tract, Animal, Animal Studies, Animals, Anthocyanins/analysis/pharmacology, Anticarcinogenic Agents/*analysis/pharmacology, Antineoplastic Agents – Analysis, Antineoplastic Agents – Pharmacodynamics, Benzopyrans – Analysis, Benzopyrans – Pharmacodynamics, Berry, Biological, Bishayee Anupam, Cancer, Chemoprevention, Clinical Trials, Clinical Trials as Topic, Critical reviews in food science and nutrition, Digestion – Drug Effects, Digestion/drug effects, Disease Models, Do Chau, Ellagic Acid/analysis/pharmacology, Fruit, Fruit/*chemistry, Gastrointestinal Neoplasms – Prevention and Control, Gastrointestinal Neoplasms/*prevention & control, Haskell Yennie, Human, Humans, Models, Mohandas Nima, Phytochemicals – Analysis, Phytochemicals – Pharmacodynamics, Phytochemicals/analysis/pharmacology, Plant Extracts – Analysis, Plant Extracts – Pharmacodynamics, Plant Extracts/*analysis/pharmacology, Polyphenols – Analysis, Polyphenols – Pharmacodynamics, Polyphenols/analysis/pharmacology, Sethi Gautam, Siveen Kodappully Sivaraman, Stoner Gary D, Treatment
Resveratrol and liver disease: from bench to bedside and community.
Tags: 2010, Acetaminophen/metabolism, Anti-Inflammatory Agents, Antioxidants/therapeutic use, Bishayee Anupam, Carbon Tetrachloride/metabolism, Cytokines/metabolism, Darvesh Altaf S, Department of Pharmaceutical Sciences, Ethanol/metabolism, Free Radicals/metabolism, Glutathione/metabolism, Hepatocytes/drug effects/pathology, Humans, Liver Diseases/*drug therapy/epidemiology, Liver international : official journal of the International Association for the Study of the Liver, McGory Robb, NEOMED College of Pharmacy, NF-kappa B/antagonists & inhibitors, Non-Steroidal/therapeutic use, Politis Themos, Resveratrol, Stilbenes/pharmacokinetics/*pharmacology/therapeutic use/toxicity
Resveratrol in the chemoprevention and treatment of hepatocellular carcinoma.
Tags: 2010, Anticarcinogenic Agents/*therapeutic use, Antineoplastic Agents – Therapeutic Use, Bishayee Anupam, Cancer treatment reviews, Carcinoma, Darvesh Altaf S, Department of Pharmaceutical Sciences, Hepatocellular – Drug Therapy, Hepatocellular – Prevention and Control, Hepatocellular/*drug therapy/*prevention & control, Humans, Liver Neoplasms – Drug Therapy, Liver Neoplasms – Prevention and Control, Liver Neoplasms/*drug therapy/*prevention & control, NEOMED College of Pharmacy, Politis Themos, Resveratrol, Stilbenes – Therapeutic Use, Stilbenes/*therapeutic use
Resveratrol suppresses oxidative stress and inflammatory response in diethylnitrosamine-initiated rat hepatocarcinogenesis.
Tags: 2010, Animals, Antioxidants/*pharmacology/therapeutic use, Antitumor, Barnes Kendra F, Bhatia Deepak, Bishayee Anupam, Cancer prevention research (Philadelphia, Pa.), Carcinogens/toxicity, Carroll Richard T, Chemical and Drug Induced Liver Injury/*etiology/metabolism/pathology, Darvesh Altaf S, Department of Pharmaceutical Sciences, Diethylnitrosamine/toxicity, Dose-Response Relationship, Drug, Drug Screening Assays, Enzyme Induction/drug effects, Experimental/chemically induced/metabolism/pathology/*prevention & control, Female, Hyperplasia, Inflammation/*prevention & control, Lipid Peroxidation/drug effects, Liver Neoplasms, Liver/drug effects/metabolism/pathology, Messenger/biosynthesis/genetics, NEOMED College of Pharmacy, NF-E2-Related Factor 2/biosynthesis/genetics, Nitric Oxide Synthase Type II/biosynthesis/genetics, Oxidative Stress/*drug effects, Phenobarbital/toxicity, Precancerous Conditions/*chemically induced/metabolism/pathology, Rats, Resveratrol, RNA, Sprague-Dawley, Stilbenes/*pharmacology/therapeutic use, Tyrosine/analogs & derivatives/analysis
Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: inhibition of cell proliferation and induction of apoptosis.
Tags: 2009, Animal, Animals, Anticarcinogenic Agents/*antagonists & inhibitors/pharmacology, Antitumor, Apoptosis/*drug effects, Bishayee Anupam, Body Weight/drug effects, Cell Proliferation/drug effects, Chemico-biological interactions, Dhir Neetika, Diethylnitrosamine, Disease Models, Dose-Response Relationship, Drinking/drug effects, Drug, Drug Screening Assays, Eating/drug effects, Experimental/chemically induced/pathology/*prevention & control, Female, Immunohistochemistry, Liver Neoplasms, Organ Size/drug effects, Phenobarbital, Proto-Oncogene Proteins c-bcl-2/biosynthesis, Rats, Resveratrol, Sprague-Dawley, Stilbenes/*pharmacology
Selenium in the prevention and treatment of hepatocellular carcinoma.
Tags: 2010, Animal, Animals, Anti-cancer agents in medicinal chemistry, Anticarcinogenic Agents/*therapeutic use, Bishayee Anupam, Carcinoma, Darvesh Altaf S, Department of Pharmaceutical Sciences, Hepatocellular/chemically induced/*drug therapy/etiology/*prevention & control, Humans, Liver Neoplasms/chemically induced/*drug therapy/etiology/*prevention & control, Models, NEOMED College of Pharmacy, Oxidative Stress, Selenium/*therapeutic use
Sequential activation of Elk-1/Egr-1/GADD45alpha by arsenic.
Tags: 2014, Arsenic/*pharmacology, Bhatia Deepak, Bishayee Anupam, Bronchi/cytology/drug effects/metabolism, Cell Cycle Proteins/biosynthesis/genetics/*metabolism, Cell Line, Early Growth Response Protein 1/biosynthesis/genetics/*metabolism, Epithelial Cells/drug effects/metabolism, ets-Domain Protein Elk-1/biosynthesis/genetics/*metabolism, Genetic, Humans, MAP Kinase Signaling System, Messenger/biosynthesis/genetics, Nuclear Proteins/biosynthesis/genetics/*metabolism, Oncotarget, Promoter Regions, Proto-Oncogene Proteins c-akt/metabolism, RNA, Shi Qiwen, Sutariya Vijaykumar
Suppression of inflammatory cascade is implicated in methyl amooranin-mediated inhibition of experimental mammary carcinogenesis.
Tags: 2014, Animals, Anti-Inflammatory Agents/pharmacology, Anticarcinogenic Agents/*pharmacology, Antineoplastic Agents/*pharmacology, Apoptosis/drug effects, Bhatia Deepak, Bishayee Anupam, Breast Neoplasms/*drug therapy/metabolism, breast tumor, Carcinogenesis/*drug effects, Cell Proliferation/drug effects, Chemoprevention/methods, COX-2, Cyclooxygenase 2/metabolism, DMBA, Down-Regulation/drug effects, Experimental/*drug therapy/metabolism, Female, HSP90, HSP90 Heat-Shock Proteins/metabolism, I-kappa B Proteins/metabolism, Inflammation, Inflammation/*drug therapy/metabolism, Mammary Neoplasms, Mandal Animesh, Molecular carcinogenesis, NF-kappa B/metabolism, NF-kappaB, NF-KappaB Inhibitor alpha, oleanane triterpenoid, Oleanolic Acid/*analogs & derivatives/pharmacology, Rats, Sprague-Dawley
Suppression of the inflammatory cascade is implicated in resveratrol chemoprevention of experimental hepatocarcinogenesis.
Tags: 2010, Animals, Anticarcinogenic Agents/*therapeutic use, Barnes Kendra F, Bhatia Deepak, Bishayee Anupam, Chatterjee Malay, Chemoprevention, Cyclooxygenase 2/immunology, Darvesh Altaf S, Department of Pharmaceutical Sciences, Diethylnitrosamine, Female, HSP70 Heat-Shock Proteins/immunology, Humans, Inflammation/prevention & control, Liver Neoplasms/chemically induced/*immunology/*prevention & control, Liver/drug effects/pathology, Mbimba Thomas, NEOMED College of Pharmacy, NF-kappa B/immunology, Pharmaceutical research, Rats, Resveratrol, Sprague-Dawley, Stilbenes/*therapeutic use, Waghray Abhijeet
Terpenoids and breast cancer chemoprevention.
Terpenoids as potential chemopreventive and therapeutic agents in liver cancer.
The health benefits of blackcurrants.
Tags: *Health Promotion, *Ribes/chemistry, 2012, Ahmed Shamima, Anthocyanins/analysis, Anti-Infective Agents, Anti-Inflammatory Agents, Antineoplastic Agents, Antioxidants, Bishayee Anupam, Darvesh Altaf S, Department of Pharmaceutical Sciences, Fatty Acids, Flavonoids/analysis, Food & function, Fruit/chemistry, Gopalan Ashwin, Hohmann Judit, Humans, NEOMED College of Pharmacy, Phytogenic, Phytotherapy, Plant Extracts/adverse effects/pharmacokinetics/pharmacology, Reuben Sharon C, Unsaturated/analysis
Trianthema portulacastrum Linn. displays anti-inflammatory responses during chemically induced rat mammary tumorigenesis through simultaneous and differential regulation of NF-kappaB and Nrf2 signaling pathways.
Tags: 10-Dimethyl-1, 2-benzanthracene/toxicity, 2015, 9, Aerial/chemistry/metabolism, Aizoaceae/*chemistry/metabolism, Animals, Anti-Inflammatory Agents/chemistry/isolation & purification/*pharmacology, Bishayee Anupam, Breast Neoplasms/chemically induced/metabolism/pathology, Cyclooxygenase 2/metabolism, Female, HSP90 Heat-Shock Proteins/metabolism, Immunohistochemistry, International journal of molecular sciences, Mandal Animesh, NF-E2-Related Factor 2/*metabolism, NF-kappa B/*metabolism, Plant Components, Plant Extracts/chemistry, Rats, Signal Transduction/*drug effects, Sprague-Dawley, Up-Regulation/drug effects
Trianthema portulacastrum Linn. exerts chemoprevention of 7,12-dimethylbenz(a)anthracene-induced mammary tumorigenesis in rats.
Tags: *Dietary Supplements, *Mammary Neoplasms, 10-Dimethyl-1, 2-benzanthracene/*toxicity, 2014, 9, Aizoaceae/*chemistry, Animals, Apoptosis, Bax, Bcl-2, bcl-2-Associated X Protein/metabolism, beta-catenin, Bishayee Anupam, breast cancer, Carcinogens/*toxicity, Cell Proliferation, Cell Proliferation/drug effects, Chemoprevention, Cyclin D1, DMBA, Experimental/chemically induced/metabolism/pathology/prevention & control, Humans, Male, Mandal Animesh, Medicinal/*chemistry, Mutation research, Phytotherapy/*methods, Plants, Proliferating Cell Nuclear Antigen/metabolism, Rats, Sprague-Dawley, Trianthema portulacastrum, Up-Regulation/drug effects, Wnt Signaling Pathway/drug effects
Triterpenoids as potential agents for the chemoprevention and therapy of breast cancer.
Tags: 2011, Ahmed Shamima, Animals, Anticarcinogenic Agents/chemistry/*therapeutic use, Antineoplastic Agents, Bishayee Anupam, Brankov Nikoleta, Breast Neoplasms/*drug therapy/*prevention & control, Chemoprevention, Frontiers in bioscience (Landmark edition), Glycosides/therapeutic use, Humans, Mice, Oleanolic Acid/analogs & derivatives/therapeutic use, Perloff Marjorie, Phytogenic/therapeutic use, Triterpenes/*therapeutic use