Browse Items (332 total)
- Tags: Department of Pharmaceutical Sciences
Structure-activity and in vivo evaluation of a novel lipoprotein lipase (LPL) activator.
Tags: *Diabetes, *High-fat diet, *Homology modeling, *Hyperlipidemia, *Lipoprotein lipase, *Liver cirrhosis, *Obesity, 2017, Animals, Benzeneacetamides/chemical synthesis/chemistry/*pharmacology, Bioorganic & medicinal chemistry letters, Caporoso Joel, Darvesh Altaf S, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Dose-Response Relationship, Drug, Geldenhuys Werner J, Imidazoles/chemical synthesis/chemistry/*pharmacology, Lee Yoon-Kwang, Leeper Thomas C, Lin Li, Lipoprotein Lipase/*metabolism, Mice, Molecular Docking Simulation, Molecular Structure, NEOMED College of Graduate Studies, NEOMED College of Medicine, NEOMED College of Pharmacy, Sadana Prabodh, Structure-Activity Relationship
Structural and Functional Rescue of Chronic Metabolically Stressed Optic Nerves through Respiration.
Tags: 2018, b-hydroxybutyrate, Crish Samuel D, Department of Pharmaceutical Sciences, Gevorgyan Victoria, Harun-Or-Rashid Mohammad, Inman Denise M, Ketogenic diet, NEOMED College of Pharmacy, neural-glial interaction, optic nerve, Palmer Peter G, Pappenhagen Nate, Smith Matthew A, The Journal of neuroscience : the official journal of the Society for Neuroscience, Wilson Gina N
Stable isotope-based flux studies in nonalcoholic fatty liver disease.
Tags: *Citric acid cycle, *Fatty acid oxidation, *Fibrosis, *NAFLD, *Oxidative Stress, *Stable isotopes, 2018, Animals, Department of Pharmaceutical Sciences, Humans, Isotopes/metabolism, Kasumov Takhar, Mass Spectrometry/*methods, McCullough Arthur, NEOMED College of Pharmacy, Non-alcoholic Fatty Liver Disease/*metabolism, Pharmacology & therapeutics, Previs Stephen
Stability of extemporaneously prepared oxandrolone oral suspensions.
Tags: 2011, Acid-Base Equilibrium, Administration, American Journal of Health-System Pharmacy, Androgens – Administration and Dosage, Cober Mary Petrea, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Descriptive Statistics, Drug Compounding, Hawkins Katherine A, Human, Johnson Cary E, Julian Justin D, NEOMED College of Pharmacy, Oral, Suspensions, Weight Gain – Chemically Induced
Stability of an extemporaneous alcohol-free melatonin suspension.
Tags: 2011, Administration, American Journal of Health-System Pharmacy, Cober Mary Petrea, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Descriptive Statistics, Drug Compounding, Drug Stability, Johnson Cary E, Melatonin, NEOMED College of Pharmacy, Oral, Rouse Emily, Suspensions, Taste, Thome Tennille
Songling Xuemaikang Capsule inhibits isoproterenol-induced cardiac hypertrophy via CaMKIIdelta and ERK1/2 pathways.
Society of Toxicology Develops Learning Framework for Undergraduate Toxicology Courses Following the Vision and Change Core Concepts Model.
Sirtuin 1 signaling and alcoholic fatty liver disease.
Single low doses of MPTP decrease tyrosine hydroxylase expression in the absence of overt neuron loss.
Tags: 1-Methyl-4-phenyl-1, 2, 2017, 3, 6-tetrahydropyridine/*administration & dosage, Alam Gelareh, Animals, Burchfield Shelbie L, Catecholamines/metabolism, Cell Count, Corpus Striatum/*drug effects/metabolism, Department of Pharmaceutical Sciences, Dopamine, Dopamine transporter, Dopaminergic Neurons/*drug effects/metabolism, Edler Melissa, Inbred C57BL, Male, Mice, MPTP, MPTP Poisoning, NEOMED College of Pharmacy, Neurotoxicology, Parkinsonian Disorders/*metabolism/*pathology, Richardson Jason R, Stereology, Substantia Nigra/*drug effects/metabolism, Tyrosine 3-Monooxygenase/*metabolism, Tyrosine hydroxylase, Vesicular monoamine transporter
Similarities and Differences between Two Modes of Antagonism of the Thyroid Hormone Receptor
Tags: 2011, Acs Chemical Biology, androgen receptor, Arnold L A, Attia R R, Biochemistry & Molecular Biology, coactivator binding, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, estrogen receptor, gene-expression, growth-hormone, Guy R K, hepatoma-cell line, hepg2, Hwang J Y, Journal Article, Liver, Neale G, NEOMED College of Graduate Studies, NEOMED College of Pharmacy, Nuclear Receptor, Sadana P, small-molecule inhibitors
Signal Transduction Mechanisms of Alcoholic Fatty Liver Disease: Emer ging Role of Lipin-1.
Tags: 2017, alcoholic fatty liver disease, Alcoholic/*metabolism/pathology, AMP-Activated Protein Kinases/metabolism, Animals, Current molecular pharmacology, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Ethanol/chemistry/*metabolism, Fatty Liver, Humans, Inflammation, Inflammation/metabolism, Jogasuria Alvin, Lee Kwangwon, Lee Yoon-Kwang, Lipid Metabolism, Lipin-1, Liver/metabolism, NEOMED College of Graduate Studies, NEOMED College of Medicine, NEOMED College of Pharmacy, Phosphatidate Phosphatase/*metabolism, Sadana Prabodh, Signal Transduction, Sirtuin 1/metabolism, transcriptional regulators, Wu Jiashin, You Min, Zhang Yanqiao
Sex differences in cognitive performance and alcohol consumption in High Alcohol-Drinking (HAD-1) rats
Tags: 2019, Alcohol use disorders, Attention, Behavioural brain research, Bell R L, Department of Pharmaceutical Sciences, Duvauchelle C L, Exploratory behavior, Fleming S M, January 2020 Update, Journal Article, Maddox W T, Martinez A, Mittal N, NEOMED College of Pharmacy, Novel object recognition, Object recognition test, Schallert T, Selectively bred high alcohol-drinking rats, Thakore N
Sequential advanced pharmacy practice experiences at one institution for students from three pharmacy schools.
Tags: *Pharmacists, *Professional Practice, *Students, 2014, Academic Medical Centers, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, Clinical, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Descriptive Statistics, Education, Goldman Morton P, Human, Kaun Megan A, NEOMED College of Pharmacy, Outcomes of Education, Parteleno Patricia, Pharmacy, Pharmacy/*organization & administration, Preceptorship, Program Development, Program Evaluation, Program Implementation, Retrospective Design, School Admission Criteria, Schools, Students, Taylor Rebecca A, Williams Jonathan, Wisneski S Scott
Sensory Hairs in the Bowhead Whale, Balaena mysticetus (Cetacea, Mammalia).
Tags: 2015, Anatomical record (Hoboken, N.J. : 2007), anatomy, Animals, Bowhead Whale/*anatomy & histology, Cetacea, Crish Samuel D, Department of Anatomy & Neurobiology, Department of Pharmaceutical Sciences, Drake Summer E, Epidermis, George John C, hair, Hair/*anatomy & histology, Lip/anatomy & histology, NEOMED College of Medicine, NEOMED College of Pharmacy, Stimmelmayr Raphaella, Thewissen J G M, vibrissa, whale
Selenium in the prevention and treatment of hepatocellular carcinoma.
Tags: 2010, Animal, Animals, Anti-cancer agents in medicinal chemistry, Anticarcinogenic Agents/*therapeutic use, Bishayee Anupam, Carcinoma, Darvesh Altaf S, Department of Pharmaceutical Sciences, Hepatocellular/chemically induced/*drug therapy/etiology/*prevention & control, Humans, Liver Neoplasms/chemically induced/*drug therapy/etiology/*prevention & control, Models, NEOMED College of Pharmacy, Oxidative Stress, Selenium/*therapeutic use
Selective Targeting of Heme Protein in Cytochrome P450 and Nitric Oxide Synthase by Diphenyleneiodonium.
Tags: *cytochrome P450, *flavoenzymes, *heme, *nitric oxide synthase, *Reactive oxygen species, 2016, Aleksunes Lauren M, Animals, Cytochrome P-450 Enzyme Inhibitors/*pharmacology, Cytochrome P-450 Enzyme System/*metabolism, Department of Pharmaceutical Sciences, Dose-Response Relationship, Drug, Heck Diane E, Heindel Ned D, Heme/*antagonists & inhibitors/metabolism, Humans, Jan Yi-Hua, Laskin Debra L, Laskin Jeffrey D, Liver/drug effects/enzymology, Mice, Microsomes, Mishin Vladimir, NEOMED College of Pharmacy, Nitric Oxide Synthase Type II/*antagonists & inhibitors/metabolism, Nitric Oxide/metabolism, Onium Compounds/*pharmacology, Rats, Recombinant Proteins/metabolism, Richardson Jason R, Sprague-Dawley, Szilagyi John T, Time Factors, Toxicological sciences : an official journal of the Society of Toxicology
Second-year pharmacy students' perceptions of adhering to a complex simulated medication regimen.
Tags: *Perception, 2012, adherence, American journal of pharmaceutical education, Curriculum/standards, Data Collection/methods/standards, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Education, Hamer David, Humans, Lehotsky Kristin, Medication Adherence/*psychology, medications, NEOMED College of Pharmacy, pharmacy students, Pharmacy/*methods/standards, Pharmacy/*psychology, Students, Ulbrich Timothy
Screening and identification of novel compounds with potential anti-proliferative effects on gallium-resistant lung cancer through an AXL kinase pathway.
Tags: 2014, Alazizi Adnan, Antineoplastic Agents/chemical synthesis/chemistry/*pharmacology, Antitumor, AXL, Bioorganic & medicinal chemistry letters, Cell Line, Cell Proliferation/drug effects, Cell Survival/drug effects, Department of Pharmaceutical Sciences, Dose-Response Relationship, Drug, Drug Resistance, Drug Screening Assays, Gallium, Gallium-resistance, Gallium/pharmacology, Geldenhuys Werner J, Humans, Lin Li, Liva Sophia, Lung cancer, Lung Neoplasms/drug therapy/*enzymology/*pathology, Molecular Structure, Naphthalenes/chemistry/*pharmacology, NEOMED College of Pharmacy, Neoplasm/drug effects, Oyewumi Moses O, Proto-Oncogene Proteins/*antagonists & inhibitors/metabolism, Pyrazoles/chemistry/*pharmacology, Quinolines/chemistry/*pharmacology, Receptor Protein-Tyrosine Kinases/*antagonists & inhibitors/metabolism, Structure-Activity Relationship, Tetrazoles/chemistry/*pharmacology, Tumor, Virtual screening
Role of Markers of Heavy Metal Metabolism in Identification of Hepatic Fibrosis in Patients With Non-Alcoholic Fatty Liver Disease (NAFLD)
Tags: 2020, Aggarwal Manik, American Journal of Gastroenterology, Department of Pharmaceutical Sciences, February 2021 List, Heavy Metals, hepatic fibrosis, journalArticle, Kasumov T, McCullough A, Mitchell B, NEOMED College of Pharmacy, non-alcoholic steatohepatitis (NASH), Non-alcoholic Fatty Liver Disease, Oxidative Stress, Singh AD
RNAseq analysis of hippocampal microglia after kainic acid-induced seizures.
Tags: 2018, Animals, Bosco Dale B, Department of Pharmaceutical Sciences, Eyo Ukpong B, Feng Lijie, Gene Expression Profiling, Gene Ontology, Hippocampus/*pathology, Huang Jun, Immunity, Interferon-beta/metabolism, Kainic Acid, Mice, Microglia/*metabolism/*pathology, Molecular brain, NEOMED College of Pharmacy, Peng Jiyun, Richardson Jason R, RNA/*methods, Seizures/*chemically induced, Sequence Analysis, Signal Transduction/genetics, Tang Ke, Up-Regulation/genetics, Wang Hui, Wu Gongxiong, Wu Long-Jun, Xu Zhiyan, Yan Cheng, Zheng Jiaying
Reversal of metabolic disorders by pharmacological activation of bile acid receptors TGR5 and FXR.
Tags: *Atherosclerosis, *Farnesoid X receptor, *NAFLD, *Obesity, *TGR5, 2018, Adorini Luciano, Animals, Bile Acids and Salts/pharmacology/*therapeutic use, Cytoplasmic and Nuclear/*agonists, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Diet, G-Protein-Coupled/*agonists, Hep G2 Cells, High-Fat/adverse effects, Humans, Hypercholesterolemia/*drug therapy/etiology/metabolism, Inbred C57BL, Jadhav Kavita, Kasumov Takhar, Lee Yoon Kwang, Li Yuanyuan, Male, Mice, Molecular metabolism, NEOMED College of Medicine, NEOMED College of Pharmacy, Non-alcoholic Fatty Liver Disease/*drug therapy/etiology/metabolism, Obesity/*drug therapy/etiology/metabolism, Receptors, Xu Jiesi, Xu Yang, Xu Yanyong, Yin Liya, Zhang Yanqiao, Zhu Yingdong
Reversal of metabolic disorders by pharmacological activation of bile acid receptors TGR5 and FXR.
Tags: *Atherosclerosis, *Farnesoid X receptor, *NAFLD, *Obesity, *TGR5, 2018, Adorini Luciano, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Jadhav Kavita, Kasumov Takhar, Lee Yoon-Kwang, Li Yuanyuan, Molecular metabolism, NEOMED College of Medicine, NEOMED College of Pharmacy, Xu Jiesi, Xu Yang, Xu Yanyong, Yin Liya, Zhang Yanqiao, Zhu Yingdong
Resveratrol suppresses oxidative stress and inflammatory response in diethylnitrosamine-initiated rat hepatocarcinogenesis.
Tags: 2010, Animals, Antioxidants/*pharmacology/therapeutic use, Antitumor, Barnes Kendra F, Bhatia Deepak, Bishayee Anupam, Cancer prevention research (Philadelphia, Pa.), Carcinogens/toxicity, Carroll Richard T, Chemical and Drug Induced Liver Injury/*etiology/metabolism/pathology, Darvesh Altaf S, Department of Pharmaceutical Sciences, Diethylnitrosamine/toxicity, Dose-Response Relationship, Drug, Drug Screening Assays, Enzyme Induction/drug effects, Experimental/chemically induced/metabolism/pathology/*prevention & control, Female, Hyperplasia, Inflammation/*prevention & control, Lipid Peroxidation/drug effects, Liver Neoplasms, Liver/drug effects/metabolism/pathology, Messenger/biosynthesis/genetics, NEOMED College of Pharmacy, NF-E2-Related Factor 2/biosynthesis/genetics, Nitric Oxide Synthase Type II/biosynthesis/genetics, Oxidative Stress/*drug effects, Phenobarbital/toxicity, Precancerous Conditions/*chemically induced/metabolism/pathology, Rats, Resveratrol, RNA, Sprague-Dawley, Stilbenes/*pharmacology/therapeutic use, Tyrosine/analogs & derivatives/analysis
Resveratrol in the chemoprevention and treatment of hepatocellular carcinoma.
Tags: 2010, Anticarcinogenic Agents/*therapeutic use, Antineoplastic Agents – Therapeutic Use, Bishayee Anupam, Cancer treatment reviews, Carcinoma, Darvesh Altaf S, Department of Pharmaceutical Sciences, Hepatocellular – Drug Therapy, Hepatocellular – Prevention and Control, Hepatocellular/*drug therapy/*prevention & control, Humans, Liver Neoplasms – Drug Therapy, Liver Neoplasms – Prevention and Control, Liver Neoplasms/*drug therapy/*prevention & control, NEOMED College of Pharmacy, Politis Themos, Resveratrol, Stilbenes – Therapeutic Use, Stilbenes/*therapeutic use
Resveratrol and liver disease: from bench to bedside and community.
Tags: 2010, Acetaminophen/metabolism, Anti-Inflammatory Agents, Antioxidants/therapeutic use, Bishayee Anupam, Carbon Tetrachloride/metabolism, Cytokines/metabolism, Darvesh Altaf S, Department of Pharmaceutical Sciences, Ethanol/metabolism, Free Radicals/metabolism, Glutathione/metabolism, Hepatocytes/drug effects/pathology, Humans, Liver Diseases/*drug therapy/epidemiology, Liver international : official journal of the International Association for the Study of the Liver, McGory Robb, NEOMED College of Pharmacy, NF-kappa B/antagonists & inhibitors, Non-Steroidal/therapeutic use, Politis Themos, Resveratrol, Stilbenes/pharmacokinetics/*pharmacology/therapeutic use/toxicity
Results of the promoting effective advance care planning for elders (PEACE) randomized pilot study.
Tags: *Quality of Life, 2014, 80 and over, Activities of Daily Living, advance care planning, Advance Care Planning/*organization & administration, Aged, Albanese Teresa H, Allen Kyle R, Case Management – Methods, Chi Square Test, College of Medicine, Community-Institutional Relations, Comparative Studies, Decision Making, Department of Family & Community Medicine, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Descriptive Statistics, Disease Management, Ertle Denise, Family, Female, Fosnight Susan M, Frail Elderly, Geriatric Assessment/methods, Hazelett Susan E, Health Promotion, Health Resource Utilization, Health Services for the Aged/organization & administration, Home Care Services/*organization & administration, Human, Humans, Interdisciplinary Communication, Kropp Denise J, Long Term Care, Long-Term Care/*organization & administration, Male, Medicaid – Ohio, Moore Pamela S, Multidisciplinary Care Team, NEOMED College of Medicine, NEOMED College of Pharmacy, Ohio, Outcomes (Health Care), Palliative Care, Palliative Care/organization & administration, Patient, Physicians, Pilot Projects, Pilot Studies – Ohio, Population health management, Program Evaluation, Psychological Tests, Quality of Life, Radwany Steven M, Random Assignment, Reference Values, Repeated Measures, Scales, Spiritual Care, T-Tests, Treatment Outcome
Requisite Role of Kv1.5 Channels in Coronary Metabolic Dilation.
Tags: 129 Strain, 2015, Animals, Bardakjian Raffi, Bratz Ian, Cardiac function, Chilian William M, Circulation research, contrast echocardiography, Coronary Circulation/*physiology, Coronary Vessels/*metabolism, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Enrick Molly, Fu Frances Kwan, Graham Jacqueline, Hakobyan Tatevik, Hou Huagang, Hydrogen peroxide, Inbred C57BL, ion channel, Janota Danielle, Khan Nadeem, Kmetz John, Knockout, Kolz Christopher, Kuppusamy Periannan, Kv1.5 Potassium Channel/*physiology, Lindner Jonathan R, Logan Suzanna, Luli Jordan, Mice, Muscle, Nagane Masaki, NEOMED College of Medicine, NEOMED College of Pharmacy, Ohanyan Vahagn, Oyewumi Moses O, Smooth, Transgenic, Transgenic mice, Vascular/*metabolism, vasodilation, Vasodilation/*physiology, voltage-gated potassium channels, Yin Liya
Repackaging of Intravenous Fat Emulsions: A Clinical Conundrum.
Tags: 2016, Cober M Petrea, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Drug Packaging – Methods, Drug Packaging/*methods, Fat Emulsions, Humans, Infant, Intravenous – Administration and Dosage, intravenous fat emulsions, Intravenous/*administration & dosage, Medication Errors – Prevention and Control, Medication Errors/*prevention & control, NEOMED College of Pharmacy, neonates, Newborn, Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, parenteral nutrition, Parenteral Nutrition – Methods, parenteral nutrition solutions, Parenteral Nutrition/*methods, Pediatrics
Relationships between Very Low-Density Lipoproteins-Ceramides, -Diacylglycerols, and -Triacylglycerols in Insulin-Resistant Men.
Tags: 2020, Biomarkers, Ceramides, Department of Pharmaceutical Sciences, Disease, Gaballah Ayman, Garrett Timothy J, Humans, Inflammation, journalArticle, June 2020 Update II, Kasumov Takhar, Kinetics, LDL, Lipids, Manrique-Acevedo Camila, Metabolic syndrome, Mucinski Justine M, NAFLD, NEOMED College of Pharmacy, obese men, Parks Elizabeth J, secretion, sphingolipids, VLDL
Relationships among gender, age, time, and temperature in methamphetamine-induced striatal dopaminergic neurotoxicity.
Tags: 2010, 3, 4-Dihydroxyphenylacetic Acid/metabolism, Age Factors, Animals, Body Temperature/drug effects, Central Nervous System Stimulants/*toxicity, Corpus Striatum/*drug effects/metabolism, Darvesh A S, Department of Pharmaceutical Sciences, Dluzen D E, Dopamine/*metabolism, Female, In Vitro Techniques, Male, McDermott J L, Methamphetamine/*toxicity, Mice, NEOMED College of Pharmacy, Neuroscience, Neurotoxicity Syndromes/etiology/*metabolism/physiopathology, Sex Factors, Time Factors