Browse Items (132 total)
- Tags: Dose-Response Relationship
Glycinergic "inhibition" mediates selective excitatory responses to combinations of sounds.
Tags: *Sound, 2008, Acoustic Stimulation/methods, Action Potentials/drug effects/physiology, Animals, Auditory Pathways/*physiology, Chiroptera/physiology, College of Anatomy & Neurobiology, Department of Anatomy & Neurobiology, Dose-Response Relationship, Drug Interactions, Excitatory Amino Acid Antagonists/pharmacology, GABA Agents/pharmacology, GABA/physiology, Gans Donald, Glycine Agents/pharmacology, Glycine/*physiology, Inferior Colliculi/cytology/drug effects/*physiology, Iontophoresis/methods, N-Methyl-D-Aspartate/antagonists & inhibitors/physiology, NEOMED College of Medicine, Neural Inhibition/drug effects/*physiology, Neurons/drug effects/physiology/radiation effects, Piperazines/pharmacology, Radiation, Receptors, Sanchez Jason Tait, The Journal of neuroscience : the official journal of the Society for Neuroscience, Wenstrup Jeffrey J
A Rare Case of Tubulointerstitial Nephritis and Uveitis Syndrome Treated with a Multi-Specialty Approach.
Tags: 2016, Biopsy, Combination, Department of Internal Medicine, Diagnosis, Differential, Dose-Response Relationship, Drug, Drug Therapy, Erzurum Sergul, Female, Follow-Up Studies, Glucocorticoids/administration & dosage, Hiremath Siri, Humans, Interstitial/diagnosis/*drug therapy, Kidney/*diagnostic imaging, NEOMED College of Medicine, Nephritis, Prednisolone/administration & dosage/*analogs & derivatives, Prednisone/*administration & dosage, Purt Boonkit, Recurrence, Sarac Erdal, Smith Sarah, The American journal of case reports, Uveitis/diagnosis/*drug therapy, Young Adult
Vagal afferents reflexly inhibit exercise in conscious rats.
Tags: 1994, Action Potentials/drug effects/physiology, Afferent Pathways/drug effects/physiology, Animals, Biguanides/administration & dosage/*pharmacology, Blood Pressure/drug effects/physiology, Chen C Y, Collins H L, Consciousness, DiCarlo S E, Dose-Response Relationship, Drug, Electromyography, Heart Rate/drug effects/physiology, Medicine and science in sports and exercise, Motor Activity/*drug effects/*physiology, Muscles/drug effects/physiology, Physical Exertion/*physiology, Rats, Reflex/*drug effects/*physiology, Serotonin Receptor Agonists/administration & dosage/*pharmacology, Sprague-Dawley, Vagus Nerve/*drug effects/*physiology
Acute exercise attenuates phenylephrine-induced contraction of rabbit isolated aortic rings.
Tags: *Physical Conditioning, 1992, Adrenergic, alpha/physiology, Animal, Animals, Aorta/physiology, DiCarlo S E, Dose-Response Relationship, Drug, Howard M G, In Vitro Techniques, Medicine and science in sports and exercise, Muscle, Muscle Contraction/*drug effects, Phenylephrine/*pharmacology, Rabbits, Receptors, Smooth, Stallone J N, Vascular/*drug effects/physiology
Preferential increase in pituitary prolactin versus vasoactive intestinal peptide as a function of estradiol benzoate dose in the ovariectomized rat.
Tags: 1991, Animals, Brain/drug effects/*metabolism, Carrillo A J, Doherty P C, Dose-Response Relationship, Drug, Endocrinology, Estradiol/*pharmacology, Female, Guan X B, Inbred Strains, Organ Specificity, Ovariectomy, Pituitary Gland/drug effects/*metabolism, Prolactin/blood/*metabolism, Rats, Sturtevant J R, Thyrotropin/blood/metabolism, Vasoactive Intestinal Peptide/*metabolism, Walro D G
Antitumor efficacy and tolerability of systemically administered gallium acetylacetonate-loaded gelucire-stabilized nanoparticles.
Tags: *Lethal Dose 50, 2013, Adenocarcinoma/*drug therapy/pathology, Animals, Antineoplastic Agents/administration & dosage/pharmacokinetics/toxicity, Bi Lipeng, Cell Line, Department of Pharmaceutical Sciences, Dose-Response Relationship, Drug, Drug Stability, Drug Tolerance, Gallium/*administration & dosage/pharmacokinetics/*toxicity, Geldenhuys Werner J, Humans, Journal of biomedical nanotechnology, Metabolic Clearance Rate, Mice, Nanocapsules/*administration & dosage/chemistry/*toxicity, NEOMED College of Pharmacy, Nude, Organ Specificity, Oyewumi Moses O, Tissue Distribution, Treatment Outcome, Triglycerides/chemistry, Tumor, Wehrung Daniel
An open-label dose escalation study to evaluate the safety of administration of nonviral stromal cell-derived factor-1 plasmid to treat symptomatic ischemic heart failure.
Tags: *Plasmids, 2013, Aged, Aras Rahul, Brain/blood, Chemokine CXCL12/*genetics/metabolism, Circulation research, Clemens Ruth, Cohort Studies, Dose-Response Relationship, Drug, Echocardiography, Exercise Tolerance, Farr Maryjane, Female, Follow-Up Studies, Genetic Therapy/*adverse effects/*methods, Heart Failure/metabolism/pathology/*therapy, Humans, Losordo Douglas W, Male, Mendelsohn Farrell O, Middle Aged, Myocardium/metabolism/pathology, Natriuretic Peptide, Pastore Joseph, Penn Marc S, Peptide Fragments/blood, Positron-Emission Tomography, Quality of Life, Rouy Didier, Schaer Gary L, Sherman Warren, Treatment Outcome
Effects of estrogen and related agents upon methamphetamine-induced neurotoxicity within an impaired nigrostriatal dopaminergic system of ovariectomized mice.
Tags: 2006, 3, 4-Dihydroxyphenylacetic Acid/metabolism, Androgens/administration & dosage, Animals, Dluzen Dean E, Dopamine Agents/*administration & dosage/toxicity, Dopamine/metabolism, Dose-Response Relationship, Drug, Drug Administration Schedule, Estradiol/administration & dosage/*analogs & derivatives/physiology, Estrogen Antagonists/administration & dosage, Female, Liu Bin, Methamphetamine/*administration & dosage/toxicity, Mice, Neostriatum/*drug effects/metabolism, Nerve Degeneration/chemically induced/prevention & control, Neuroendocrinology, Neuroprotective Agents/administration & dosage, Neurotoxins/*administration & dosage, Ovariectomy, Parkinson Disease/physiopathology, Substantia Nigra/*drug effects/metabolism, Tamoxifen/administration & dosage
Dose-response effects of estrogen and tamoxifen upon methamphetamine-induced behavioral responses and neurotoxicity of the nigrostriatal dopaminergic system in female mice.
Tags: 2004, 3, 4-Dihydroxyphenylacetic Acid/metabolism, Animal/*drug effects, Animals, Behavior, Brain Chemistry/drug effects, Dluzen Dean E, Dopamine/*metabolism, Dose-Response Relationship, Drug, Drug Interactions, Estrogen Antagonists/pharmacology, Estrogens/*pharmacology, Female, Methamphetamine/*toxicity, Mice, Mickley Katherine R, Movement/drug effects, Neostriatum/*drug effects/physiology, Neuroendocrinology, Neurotoxins/*toxicity, Organ Size/drug effects, Ovariectomy/methods, Stereotyped Behavior/drug effects, Substantia Nigra/drug effects/physiology, Tamoxifen/*pharmacology, Uterus
Resveratrol suppresses oxidative stress and inflammatory response in diethylnitrosamine-initiated rat hepatocarcinogenesis.
Tags: 2010, Animals, Antioxidants/*pharmacology/therapeutic use, Antitumor, Barnes Kendra F, Bhatia Deepak, Bishayee Anupam, Cancer prevention research (Philadelphia, Pa.), Carcinogens/toxicity, Carroll Richard T, Chemical and Drug Induced Liver Injury/*etiology/metabolism/pathology, Darvesh Altaf S, Department of Pharmaceutical Sciences, Diethylnitrosamine/toxicity, Dose-Response Relationship, Drug, Drug Screening Assays, Enzyme Induction/drug effects, Experimental/chemically induced/metabolism/pathology/*prevention & control, Female, Hyperplasia, Inflammation/*prevention & control, Lipid Peroxidation/drug effects, Liver Neoplasms, Liver/drug effects/metabolism/pathology, Messenger/biosynthesis/genetics, NEOMED College of Pharmacy, NF-E2-Related Factor 2/biosynthesis/genetics, Nitric Oxide Synthase Type II/biosynthesis/genetics, Oxidative Stress/*drug effects, Phenobarbital/toxicity, Precancerous Conditions/*chemically induced/metabolism/pathology, Rats, Resveratrol, RNA, Sprague-Dawley, Stilbenes/*pharmacology/therapeutic use, Tyrosine/analogs & derivatives/analysis
Leading inhibition to neural oscillation is important for time-domain processing in the auditory midbrain.
Tags: *Periodicity, 2005, Acoustic Stimulation/methods, Action Potentials/drug effects/physiology, Animals, Anura, Auditory Pathways/physiology, Bicuculline/pharmacology, Chiroptera, Department of Anatomy & Neurobiology, Dose-Response Relationship, Echolocation/*physiology, Feng Albert S, GABA Antagonists/pharmacology, Galazyuk Alexander V, Journal of neurophysiology, Lin Wenyu, Llano Daniel, Mesencephalon/*cytology/physiology, NEOMED College of Medicine, Neural Inhibition/drug effects/*physiology, Neurons/drug effects/*physiology, Newborn, Radiation, Reaction Time/drug effects/*physiology, Sound, Species Specificity, Time Factors
Dose-response relationship between plasma epinephrine concentration and alveolar liquid clearance in dogs.
Tags: 1998, Algorithms, Animals, Blood Pressure/drug effects/physiology, Cardiac Output/drug effects/physiology, Catecholamines/blood, Dogs, Dose-Response Relationship, Drug, Epinephrine/*blood, Female, Hematocrit, Journal of applied physiology (Bethesda, Md. : 1985), Male, Maron M B, Pulmonary Alveoli/*physiopathology, Pulmonary Circulation/drug effects/physiology, Pulmonary Edema/*blood/*physiopathology, Pulmonary Wedge Pressure/drug effects/physiology
Reduced vascular responsiveness after a single bout of dynamic exercise in the conscious rabbit.
Tags: 1992, Adenosine/pharmacology, Adrenergic/physiology, Animals, Blood Vessels/*physiology, DiCarlo S E, Dose-Response Relationship, Drug, Hindlimb/physiology, Howard M G, In Vitro Techniques, Isoproterenol/pharmacology, Journal of applied physiology (Bethesda, Md. : 1985), Phenylephrine/pharmacology, Physical Exertion/*physiology, Pressoreceptors/physiology, Purinergic/physiology, Rabbits, Receptors, Reflex/physiology, Regional Blood Flow/physiology
Mesenteric vascular responses to vasopressin during development of DOCA-salt hypertension in male and female rats.
Tags: 1995, 6-Ketoprostaglandin F1 alpha/metabolism, Analysis of Variance, Animals, Arginine Vasopressin/*pharmacology, Blood Pressure/drug effects, Desoxycorticosterone, Dietary, Dinoprostone/metabolism, Dose-Response Relationship, Drug, Female, Hypertension/chemically induced/*physiopathology, In Vitro Techniques, Male, Prostaglandins/analysis/*metabolism, Rats, Reference Values, Sex Characteristics, Sodium, Splanchnic Circulation/drug effects/*physiology, Sprague-Dawley, Stallone J N, The American journal of physiology
RNA interference for alpha-ENaC inhibits rat lung fluid absorption in vivo.
Tags: 2006, Absorption/drug effects, Adrenergic beta-Agonists/pharmacology, American journal of physiology. Lung cellular and molecular physiology, Amiloride/pharmacology, Animals, Body Fluids/*metabolism, Capillary Permeability, Dose-Response Relationship, Drug, Endothelium, Epithelial Cells/metabolism, Epithelial Sodium Channels, Epithelium/metabolism, Folkesson Hans G, Inhibitory Concentration 50, Li Tianbo, Lung/enzymology/*metabolism, Male, Messenger/antagonists & inhibitors/metabolism, Permeability, Plasmids/administration & dosage/pharmacology, Rats, RNA, Small Interfering/genetics/pharmacology, Sodium Channels/drug effects/genetics/metabolism/*physiology, Sprague-Dawley, Terbutaline/pharmacology, Tissue Distribution, Vascular/metabolism
Myocardial work load is a major determinant of norepinephrine-induced left ventricular dysfunction.
Tags: 1994, Allman F D, Anesthesia, Animals, Blood Pressure/*drug effects, Bosso F J, Cardiovascular, Consciousness, Diastole/drug effects, Dose-Response Relationship, Drug, General, Heart Rate/*drug effects, Heart/drug effects/*physiology, Left/drug effects/*physiology, Models, Norepinephrine/*pharmacology, Pentobarbital, Pilati C F, Rabbits, Systole/drug effects, The American journal of physiology, Time Factors, Ventricular Function
Acute exercise enhances nitric oxide modulation of vascular response to phenylephrine.
Tags: *Physical Exertion, 1993, Animals, Arginine/analogs & derivatives/pharmacology, Blood Flow Velocity, Blood Pressure/drug effects, Blood Vessels/*drug effects, Collins H L, DiCarlo S E, Dose-Response Relationship, Drug, Female, Heart Rate/drug effects, Iliac Artery/drug effects/physiology, Male, NG-Nitroarginine Methyl Ester, Nitric Oxide/antagonists & inhibitors/*physiology, Patil R D, Phenylephrine/*pharmacology, Rats, Sprague-Dawley, The American journal of physiology, Time Factors, Vasoconstriction/drug effects/physiology
Sexual dimorphism in vasopressin-induced contraction of rat aorta.
Endothelin-mediated in vivo pressor responses following TRPV1 activation.
Tags: *Blood Pressure/drug effects, *Vasoconstriction/drug effects, 2011, Adrenergic alpha-Agonists/administration & dosage, American journal of physiology. Heart and circulatory physiology, Analysis of Variance, Animal, Animals, Azepines/administration & dosage, Biphenyl Compounds/administration & dosage, Bratz Ian N, Capsaicin/administration & dosage, Cells, Cultured, Damron Derek S, Department of Integrative Medical Sciences, Diabetes Mellitus, Diabetic Angiopathies/genetics/*metabolism/physiopathology, Dipeptides/administration & dosage, Disease Models, Dose-Response Relationship, Drug, Endothelial Cells/metabolism, Endothelin A Receptor Antagonists, Endothelin A/metabolism, Endothelin B Receptor Antagonists, Endothelin B/metabolism, Endothelin-1/*metabolism, Enzyme-Linked Immunosorbent Assay, Femoral Artery/drug effects/*metabolism/physiopathology, Guarini Giacinta, Haney Rebecca M, Inbred C57BL, Indoles/administration & dosage, Infusions, Intravenous, Knockout, Male, Meszaros J Gary, Mice, NEOMED College of Medicine, Ohanyan Vahagn A, Phenylephrine/administration & dosage, Raman Priya, Receptor, Talasila Phani K, Thodeti Charles K, TRPV Cation Channels/agonists/deficiency/genetics/*metabolism, Type 2/genetics/*metabolism/physiopathology, Vasoconstrictor Agents/administration & dosage
Functional selectivity of NK1 receptor signaling: peptide agonists can preferentially produce receptor activation or desensitization.
Tags: 2006, Animals, CHO Cells, Cricetinae, Dose-Response Relationship, Drug, Humans, Neurokinin-1/agonists/drug effects/*physiology, Rana catesbeiana, Rats, Receptors, Signal Transduction/*physiology, Simmons Mark A, Substance P/metabolism/pharmacology, Tachykinins/metabolism/pharmacology, The Journal of pharmacology and experimental therapeutics
Activation of metabotropic glutamate receptor 1 dimers requires glutamate binding in both subunits.
Tags: 2005, Blotting, Calcium Channels/drug effects/metabolism, Department of Integrative Medical Sciences, DNA/biosynthesis/genetics, Dose-Response Relationship, Drug, Fluorescent Antibody Technique, Genes, Glutamic Acid/*metabolism, Humans, Kammermeier Paul J, Membrane Potentials/drug effects, Metabotropic Glutamate/genetics/*metabolism, myc/genetics, NEOMED College of Medicine, Patch-Clamp Techniques, Plasmids/genetics, Receptors, Signal Transduction/drug effects, Superior Cervical Ganglion/cytology/drug effects/metabolism, Sympathetic Nervous System/cytology/drug effects/metabolism, The Journal of pharmacology and experimental therapeutics, Western, Yun June
Evaluation of factors associated with achieving glycemic control in a pharmacist-managed diabetes clinic.
Tags: 2014, Ambulatory Care, Ambulatory Care/organization & administration, American journal of therapeutics, Blood Glucose – Drug Effects, Blood Glucose/drug effects, Boros Melanie L, Department of Internal Medicine, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Diabetes Mellitus, Dose-Response Relationship, Drug, Female, Follow-Up Studies, Frazee Lawrence A, Glycated Hemoglobin A/metabolism, Glycosylated – Metabolism, Hemoglobin A, Human, Humans, Hypoglycemic Agents – Administration and Dosage, Hypoglycemic Agents – Therapeutic Use, Hypoglycemic Agents/administration & dosage/*therapeutic use, Insulin – Administration and Dosage, Insulin – Therapeutic Use, Insulin/administration & dosage/therapeutic use, Kostoff Matthew D, Male, Middle Age, Middle Aged, Moorman John M, NEOMED College of Medicine, NEOMED College of Pharmacy, Pharmaceutical Services/*organization & administration, Pharmacists – Administration, Pharmacists/*organization & administration, Pharmacy Service – Administration, Prospective Studies, Retrospective Design, Retrospective Studies, Social Work – Statistics and Numerical Data, Social Work/statistics & numerical data, Treatment Outcome, Treatment Outcomes, Type 2 – Drug Therapy, Type 2/*drug therapy
Pyrethroid Insecticides Directly Activate Microglia Through Interaction With Voltage-Gated Sodium Channels.
Tags: *deltamethrin, *intracellular sodium., *Microglia, *neurodegeneration, *Neuroinflammation, *permethrin, *pyrethroids, *tetrodotoxin, *tumor necrosis factor, *Voltage-gated sodium channels, 2017, Animals, Cell Line, Department of Pharmaceutical Sciences, Dose-Response Relationship, Drug, Hossain Muhammad M, Inbred C57BL, Insecticides/*toxicity, Ion Channel Gating/*drug effects, Liu Jason, Mice, Microglia/*drug effects/metabolism, NEOMED College of Pharmacy, Pyrethrins/*toxicity, Richardson Jason R, Sodium Channels/*drug effects, Toxicological sciences : an official journal of the Society of Toxicology, Transformed, Tumor Necrosis Factor-alpha/metabolism
Selective Targeting of Heme Protein in Cytochrome P450 and Nitric Oxide Synthase by Diphenyleneiodonium.
Tags: *cytochrome P450, *flavoenzymes, *heme, *nitric oxide synthase, *Reactive oxygen species, 2016, Aleksunes Lauren M, Animals, Cytochrome P-450 Enzyme Inhibitors/*pharmacology, Cytochrome P-450 Enzyme System/*metabolism, Department of Pharmaceutical Sciences, Dose-Response Relationship, Drug, Heck Diane E, Heindel Ned D, Heme/*antagonists & inhibitors/metabolism, Humans, Jan Yi-Hua, Laskin Debra L, Laskin Jeffrey D, Liver/drug effects/enzymology, Mice, Microsomes, Mishin Vladimir, NEOMED College of Pharmacy, Nitric Oxide Synthase Type II/*antagonists & inhibitors/metabolism, Nitric Oxide/metabolism, Onium Compounds/*pharmacology, Rats, Recombinant Proteins/metabolism, Richardson Jason R, Sprague-Dawley, Szilagyi John T, Time Factors, Toxicological sciences : an official journal of the Society of Toxicology
Resveratrol inhibition of Propionibacterium acnes.
Tags: *Anti-Bacterial Agents, 2007, Anti-Inflammatory Agents, Bailey Erin, Benzoyl Peroxide/pharmacology, Booth Tristan D, Department of Family & Community Medicine, Docherty John J, Dose-Response Relationship, Drug, Erythromycin/pharmacology, Keratolytic Agents/pharmacology, McEwen Heather A, Microbial Sensitivity Tests, NEOMED College of Medicine, Non-Steroidal/*pharmacology, Propionibacterium acnes/*drug effects/growth & development, Resveratrol, Stilbenes/*pharmacology, Sweet Thomas J, The Journal of antimicrobial chemotherapy
Secure cranial-mount intrathecal cannulation - a spinal administration technique in the rat.
Tags: 2000, Analgesics, Anesthesia, Animals, Crisp T, Dose-Response Relationship, Drug, Injections, Journal of neuroscience methods, Microinjections, Morphine/administration & dosage/pharmacology, Opioid/administration & dosage/pharmacology, Rats, Schechter J B, Spinal Cord/*physiology, Spinal/*instrumentation, Sprague-Dawley, Stereotaxic Techniques/*instrumentation
MDMA-like stimulus effects of hallucinogens in male Fawn-Hooded rats.
Tags: 1998, 4-methylenedioxyamphetamine/*pharmacology, Animals, Central Nervous System Stimulants/*pharmacology, Conditioning, Cues, Discrimination (Psychology)/drug effects, Dopamine Agents/pharmacology, Dose-Response Relationship, Drug, Generalization, Hallucinogens/*pharmacology, Inbred Strains, Male, N-Methyl-3, Operant/drug effects, Pharmacology, biochemistry, and behavior, Rats, Schechter M D, Serotonin Agents/pharmacology, Serotonin/genetics/physiology, Sprague-Dawley, Stimulus/drug effects
Rohypnol ("roofies") control of drug discrimination: effect of coadministered ethanol or flumenazil.
Tags: 1998, Animals, Anti-Anxiety Agents/*pharmacology, Discrimination Learning/*drug effects, Dose-Response Relationship, Drug, Drug Administration Schedule, Ethanol/*pharmacology, Flumazenil/*pharmacology, Flunitrazepam/*pharmacology, GABA Antagonists/*pharmacology, Male, Pharmacology, biochemistry, and behavior, Rats, Schechter M D, Sprague-Dawley
Discriminative characteristics of high and low cocaine administration: effect of other psychostimulants.
Tags: 1997, Amphetamine/pharmacology, Animals, Central Nervous System Stimulants/pharmacology, Cocaine/*pharmacology, Conditioning, Discrimination Learning/*drug effects, Dopamine Agents/*pharmacology, Dose-Response Relationship, Drug, Drug Evaluation, Generalization, Male, Methamphetamine/pharmacology, Operant/*drug effects, Pharmacology, biochemistry, and behavior, Preclinical, Propiophenones/pharmacology, Psychotropic Drugs/*pharmacology, Rats, Response/*drug effects, Schechter M D
Drug-drug discrimination: stimulus properties of drugs of abuse upon a serotonergic-dopaminergic continuum.
Tags: 1997, 4-methylenedioxyamphetamine/pharmacology, Amphetamine/pharmacology, Animals, Discrimination (Psychology)/*drug effects, Dopamine Agonists/pharmacology, Dopamine Uptake Inhibitors/pharmacology, Dopamine/*physiology, Dose-Response Relationship, Drug, Generalization, Lysergic Acid Diethylamide/pharmacology, Male, N-Methyl-3, Norfenfluramine/pharmacology, Pharmacology, biochemistry, and behavior, Propiophenones/pharmacology, Rats, Schechter M D, Serotonin Agents/pharmacology, Serotonin Receptor Agonists/pharmacology, Serotonin Uptake Inhibitors/pharmacology, Serotonin/*physiology, Stimulus, Substance-Related Disorders/*psychology, Tetrahydronaphthalenes/pharmacology, Time Factors
Serotonergic mediation of fenfluramine discriminative stimuli in fawn-hooded rats.
Tags: *Discrimination Learning, 1997, 4-methylenedioxyamphetamine/pharmacology, Animals, Dose-Response Relationship, Drug, Fenfluramine/administration & dosage/*pharmacology, Fluoxetine/pharmacology, Ibogaine/pharmacology, Life sciences, Male, Methoxydimethyltryptamines/pharmacology, N-Methyl-3, Piperazines/pharmacology, Quipazine/pharmacology, Rats, Schechter M D, Serotonin Agents/administration & dosage/*pharmacology, Serotonin Receptor Agonists/pharmacology, Serotonin/*metabolism, Sprague-Dawley
Phentermine+fenfluramine produce cocaine-like discriminative cues.
Tags: *Discrimination (Psychology), 1996, Animals, Cocaine/*pharmacology, Department of Anatomy & Neurobiology, Dose-Response Relationship, Drug, Fenfluramine/administration & dosage/*pharmacology, Life sciences, Male, McBurney D, NEOMED College of Medicine, Phentermine/administration & dosage/*pharmacology, Rats, Schechter M D, Sprague-Dawley
Sex differences in extracellular and intracellular calcium-mediated vascular reactivity to vasopressin in rat aorta.
Tags: *Sex Characteristics, 1, 1998, 3-Pyridinecarboxylic acid, 4-dihydro-2, 6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Animals, Aorta/drug effects/*metabolism, Calcium Channel Agonists/*pharmacology, Calcium Channel Blockers/*pharmacology, Calcium/*metabolism, Department of Internal Medicine, Diltiazem/pharmacology, Dose-Response Relationship, Drug, Eatman D, European journal of pharmacology, Female, In Vitro Techniques, Male, Methyl ester/pharmacology, NEOMED College of Medicine, Potassium Chloride/pharmacology, Rats, Rutecki G W, Simvastatin/pharmacology, Sprague-Dawley, Stallone J N, Vasoconstriction/*drug effects, Vasopressins/*metabolism, Whittier F C
Discrete versus cumulative dosing in dose-response discrimination studies.
Tags: 1997, 4-methylenedioxyamphetamine/*pharmacology, Animals, Chemical, Cocaine/*pharmacology, Discrimination Learning/*drug effects, Dose-Response Relationship, Drug, Drug Administration Schedule, Drug Evaluation, European journal of pharmacology, Male, N-Methyl-3, Preclinical, Rats, Schechter M D, Sprague-Dawley, Stimulation
The effects of nicotine on dopamine and DOPAC output from rat striatal tissue.
Tags: 1998, 3, 4-Dihydroxyphenylacetic Acid/*metabolism, Amphetamine/pharmacology, Anderson L I, Animals, Central Nervous System Stimulants/pharmacology, Corpus Striatum/*drug effects/*metabolism, Dluzen D E, Dopamine/*metabolism, Dose-Response Relationship, Drug, European journal of pharmacology, Ganglionic Stimulants/administration & dosage/*pharmacology, Male, Nicotine/administration & dosage/*pharmacology, Potassium Chloride/pharmacology, Rats, Sprague-Dawley
Olanzapine attenuates the reinforcing effects of cocaine.
Tags: 1997, Animal/*drug effects, Animals, Antipsychotic Agents/administration & dosage/*pharmacology, Behavior, Benzodiazepines, Cocaine/administration & dosage/antagonists & inhibitors/*pharmacology, Conditioning, Dopamine Uptake Inhibitors/administration & dosage/*pharmacology, Dose-Response Relationship, Drug, European journal of pharmacology, Food Preferences/drug effects, Male, Meil W M, Olanzapine, Operant/*drug effects, Pirenzepine/administration & dosage/*analogs & derivatives/pharmacology, Rats, Schechter M D, Self Administration, Sprague-Dawley
Discrimination of cocaethylene in rats trained to discriminate between its components.
A subtherapeutic international normalized ratio despite increasing doses of warfarin: could this be malabsorption?
Tags: *Drug Resistance, 2000, Administration, Adult, Anticoagulants/administration & dosage/metabolism/pharmacokinetics/therapeutic use, Area Under Curve, Biological Availability, Delgado L L, Department of Family & Community Medicine, Department of Internal Medicine, Dose-Response Relationship, Drug, Female, Frazee L A, Haupt K M, Humans, Injections, Intestinal Absorption/*physiology, Intravenous, Kidney Transplantation, Lara L F, NEOMED College of Medicine, Oral, Rutecki G W, The American journal of the medical sciences, Warfarin/*administration & dosage/*metabolism/pharmacokinetics/therapeutic use
Localization and function of NK(3) subtype tachykinin receptors of layer V pyramidal neurons of the guinea-pig medial prefrontal cortex.
Tags: 2008, Animals, Autoradiography/methods, Dose-Response Relationship, Drug, Drug Interactions, Excitatory Amino Acid Antagonists/pharmacology, Excitatory Postsynaptic Potentials/drug effects/radiation effects, Guinea Pigs, In Vitro Techniques, Iodine Isotopes/pharmacokinetics, Male, Medd A M, Membrane Potentials/drug effects/physiology/radiation effects, Neurokinin B/analogs & derivatives/pharmacokinetics, Neurokinin-3/agonists/antagonists & inhibitors/*metabolism, Neuroscience, Patch-Clamp Techniques, Peptide Fragments/pharmacology, Prefrontal Cortex/*cytology, Protein Binding/drug effects, Pyramidal Cells/drug effects/*metabolism, Quinolines/pharmacology, Quinoxalines/pharmacology, Receptors, Simmons M A, Sobotka-Briner C D, Substance P/analogs & derivatives/pharmacology, Valine/analogs & derivatives/pharmacology
Valproate increases dopamine transporter expression through histone acetylation and enhanced promoter binding of Nurr1.
Tags: 2017, Acetylation/drug effects, Animals, Butyrates/pharmacology, Cell Line, Cell Survival/drug effects, Department of Pharmaceutical Sciences, Dopamine Plasma Membrane Transport Proteins/*metabolism, Dopamine transporter, Dopaminergic Neurons/cytology/drug effects/metabolism, Dose-Response Relationship, Drug, Eid Aseel, Epigenesis, Epigenetics, Genetic, Genetic/drug effects, Green Ashley L, Group A, Guo Grace L, HDAC, Histone deacetylase, Histone Deacetylase Inhibitors/*pharmacology, Histone Deacetylases/metabolism, Histones/*drug effects/metabolism, Homeodomain Proteins/metabolism, Hydroxamic Acids/pharmacology, Member 2/*metabolism, Messenger/metabolism, NEOMED College of Pharmacy, Neuropharmacology, Nuclear Receptor Subfamily 4, Nurr1, Pitx3, Promoter Regions, Rats, Richardson Jason R, RNA, Transcription Factors/metabolism, Valproate, Valproic Acid/*pharmacology, Zarbl Helmut, Zhan Le