Browse Items · NEOMED Bibliography Database

Effect of influenza on outcomes in patients with heart failure.

OBJECTIVES: This study sought to determine whether influenza infection increases morbidity and mortality in patients hospitalized with heart failure (HF). BACKGROUND: Patients with HF may be at increased risk of morbidity and mortality from…

Moderation and mediation of the relationships between masculinity ideology and health status.

OBJECTIVE: The purpose of this study was to assess the direct and indirect relationships between the endorsement of traditional masculinity ideology (TMI) and self-reported health status through potential mediating variables of expectations of …

Short-term and long-term outcomes of patients undergoing urgent transcatheter aortic valve replacement under a minimalist strategy.

OBJECTIVES: Urgent transcatheter aortic valve replacement (TAVR) is associated with worse short-term outcomes compared with elective TAVR; however, little is known about long-term outcomes or the safety of the minimalist strategy in this setting. …

Tags: 2019, Aged 80 and over, Aortic Valve Stenosis/diagnosis/mortality/surgery, Aortic Valve/diagnostic imaging/surgery, Attizzani GF, Bezerra HG, Cardiac Catheterization/methods, Cleveland Clinic Akron General Hospital, Costa MA, Davis A, Department of Internal Medicine, Echocardiography Transesophageal, Elective Surgical Procedures/methods, Female, Femoral Artery, Follow-Up Studies, Hospital Mortality/trends, Humans, Ichibori Y, journalArticle, June2020SubmittedList, Kalra A, Kobe D, Ladas T, Length of Stay, Li J, Lipinski J, Male, Markowitz AH, minimalist approach, NEOMED College of Medicine, Patel S, Patel T, Peters M, Retrospective Studies, Risk Factors, Saric P, severe aortic stenosis, Severity of Illness Index, The Journal of invasive cardiology, Time Factors, transcatheter aortic valve replacement, Transcatheter Aortic Valve Replacement/methods, Treatment Outcome, Tsushima T, United States/epidemiology, urgent procedure

Level of scientific evidence underlying the current American College of Cardiology/American Heart Association clinical practice guidelines.

Relation of concomitant heart failure to outcomes in patients hospitalized with influenza.

Influenza is a major public health challenge. Patients hospitalized with influenza who also have heart failure (HF) may be at risk for worse outcomes compared with patients without HF. There is a lack of large studies examining this issue. We …

Structural heart disease: One valve does not fit all.

PURPOSE OF REVIEW: Highlight the difficulties patients, physicians, and the global economy face in relation to treatment of structural heart diseases. It is easy to be carried away by the excitement of medical advancement; however, it is difficult…

Feasibility and safety of adopting next-day discharge as first-line option after transfemoral transcatheter aortic valve replacement.

OBJECTIVES: Data on next-day discharge (NDD) after transcatheter aortic valve replacement (TAVR) are limited. This study investigated the feasibility and safety of NDD as a first-line option (the very-early discharge [VED] strategy) compared with…

Tags: 2019, Academic Medical Centers, Aged, Aged 80 and over, aortic stenosis, Aortic Valve Stenosis/diagnosis/surgery, Attizzani GF, Bezerra HG, Cleveland Clinic Akron General Hospital, Cohort Studies, Costa MA, Davis A, Department of Internal Medicine, early discharge, Feasibility Studies, Female, Follow-Up Studies, Humans, Ichibori Y, journalArticle, June2020SubmittedList, Kalra A, Length of Stay, Li J, Lipinski J, Male, Markowitz AH, minimalist approach, NEOMED College of Medicine, next-day discharge, Ohio, Panhwar M, Patel SM, Patel TM, Patient Discharge, Patient Readmission/statistics & numerical data, Patient Safety, Propensity Score, Qureshi G, Retrospective Studies, Risk Assessment, Sareyyupoglu B, Saric P, Severity of Illness Index, Survival Analysis, The Journal of invasive cardiology, Time Factors, transcatheter aortic valve replacement, Transcatheter Aortic Valve Replacement/methods/mortality, United States, Zidar DA

Management of cardiogenic shock complicating acute myocardial infarction: A review.

Despite advances in percutaneous coronary interventions and their widespread use, mortality in patients presenting with acute myocardial infarction (MI) complicated by cardiogenic shock (CS) has remained very high, and treatment options are…

Stability after initial decline in coronary revascularization rates in the united states.

BACKGROUND: It remains uncertain how advances in revascularization techniques, availability of new evidence, and updated guidelines have influenced the annual rates of coronary revascularization in the United States. METHODS: We used the …

SGLT-2 inhibitors and GLP-1 agonists: First-line therapy for diabetes with established cardiovascular disease.

There is a growing body of evidence that diabetes represents a significant and largely modifiable risk factor for cardiovascular disease (CVD). It is known to markedly increase the risk of CVD-with CVD accounting for 2 of every 3 deaths in …

Derivation and external validation of a simple risk tool to predict 30-day hospital readmissions after transcatheter aortic valve replacement.

AIMS: Patients undergoing transcatheter aortic valve replacement (TAVR) possess a higher risk of recurrent healthcare resource utilisation due to multiple comorbidities, frailty, and advanced age. We sought to devise a simple tool to identify TAVR…

An appraisal of the american psychological association's clinical practice guideline for the treatment of posttraumatic stress disorder.

In 2017, the American Psychological Association published the Clinical Practice Guidelines for the Treatment of Posttraumatic Stress Disorder (PTSD) in Adults. Although the Guideline Development Panel aimed to produce guidelines based on the best…

Tags: 2019, Adult, Attitude of Health Personnel, Comorbidity, Department of Family & Community Medicine, Evidence-Based Practice/methods/standards, Humans, journalArticle, June2020SubmittedList, Levant RF, NEOMED College of Medicine, Practice Guidelines as Topic, Professional Autonomy, PSYCHOTHERAPY, Psychotherapy/methods/standards, Silver KE, Societies Scientific, Stress Disorders Post-Traumatic/diagnosis/psychology/therapy, United States

Meta-analysis comparing outcomes in patients undergoing transcatheter aortic valve implantation with versus without percutaneous coronary intervention.

Patients having transcatheter aortic valve implantation (TAVI) routinely undergo coronary angiography before the procedure to define the coronary anatomy and to evaluate the extend of coronary artery disease (CAD). Whether percutaneous coronary …

The changing landscape of aortic valve replacement in the usa.

AIMS: The aim of this study was to analyse the real-world national data on parallel utilisation of transcatheter (TAVR) and surgical (SAVR) aortic valve replacement. METHODS AND RESULTS: We queried an all-payer, administrative United States …

Pediatric airway management in COVID-19 patients: consensus guidelines from the society for pediatric anesthesia's pediatric difficult intubation collaborative and the Canadian Pediatric Anesthesia Society.

The severe acute respiratory syndrome coronavirus 2 (coronavirus disease 2019 [COVID-19]) pandemic has challenged medical systems and clinicians globally to unforeseen levels. Rapid spread of COVID-19 has forced clinicians to care for patients with a…

Tags: 2020, Adolescent, Airway Management/ methods, Anesthesia and Analgesia, Anesthesia/methods, Anesthesiology/ methods/standards, Asaf S, Ayad I, Bhalla T, Castro P, Chiao F, Child, Consensus, Coronavirus Infections/ therapy, Crockett C, Dalesio N, Denning S, Department of General Surgery, Disma N, Engelhardt T, Evans F, Fiadjoe JE, Galvez I, Gálvez J, Garcia-Marcinkiewicz A, Glover C, Gooden C, Greenberg R, Greenwood E, Guidelines as Topic, Gumaney H, Haydar B, Hervías M, Hsu G, Humans, Hunyady A, Infant, Infection Control, Infectious Disease Transmission, Ingelmo P, Intratracheal/ methods/standards, Intubation, Jagannathan N, Javia L, journalArticle, July 2020 List, Kiss EE, Kovatsis PG, Lardner D, Lau J, Lee JK, Lee LK, Lockman JL, Matava CT, Matuszczak M, McCloskey J, Mireles S, NEOMED College of Medicine, Newborn, Olomu P, Pandemics, Park R, Patient-to-Professional/prevention & control, Pediatrics/ methods/standards, Pérez-Pradilla C, Peyton J, Pneumonia, Polaner D, Preschool, Raman VT, Rehman M, Reynolds P, Sabato S, Stein ML, Szmuk P, Szolnoki J, Taicher B, Tan J, Templeton T, Theroux MC, Thompson N, Viral/ therapy, Von Ungern-Sternberg B, Whyte S, Yaster M, Yu J

Relationships between Very Low-Density Lipoproteins-Ceramides, -Diacylglycerols, and -Triacylglycerols in Insulin-Resistant Men.

This short report describes the relationships between concentrations of ceramides (CER), diacylglycerols (DAG), triacylglycerols (TAG) in very low-density lipoproteins (VLDL) particles, and hepatic lipid accumulation. VLDL particles were isolated…

A Call for Diversity and Inclusivity in the HEC-C Program.

Tags: 2020, Aultman Julie, Bioethics, Certification, Consultants, Department of Family & Community Medicine, ETHICAL decision making, ETHICISTS, Humans, MEDICAL consultants, MEDICAL ethics, NATIONAL competency-based educational tests, NEOMED College of Graduate Studies, NEOMED College of Medicine, NEOMED College of Medicine Student, NEOMED Student Publications, Pathmathasan Cynthia, PROFESSIONAL licensure examinations, The American journal of bioethics : AJOB

Results through skeletal maturity of planned fibular nonunion for the treatment of genu varum in achondroplasia: An observational retrospective study

Current surgical options for treating genu varum in achondroplasia include tibial and fibular osteotomy and growth modulation using plates and screws. However, a single surgeon consistently treated genu varum using a planned fibular nonunion (PFN).…

The Elusive Diploic Veins: Anthropological And Anatomical Perspective

Diploic veins (Canales diploicae), which were identified in dogs by Dupuytren more than 200 years ago (Hecker [1845] Die anatomische Verhaltnisse und Krankheiten der Venae diploicae und Vasa emissaria, Erfahrungen und Abhandlungen im Gebiete der…

Tags: 1999, American journal of physical anthropology, Anthropology, diploic vein, discrete trait, Dutour O, Evolutionary Biology, Greenwald C, Hershkovitz I, Humans, Jellema L M, Journal Article or Conference Abstract Publication, Latimer B, Leonetti G, Pap I, radiator, Radiographs, Rothschild B M, Wish-Baratz S

Homozygosity for a mutation affecting the catalytic domain of tyrosyl-tRNA synthetase (YARS) causes multisystem disease

Aminoacyl-tRNA synthetases (ARSs) are critical for protein translation. Pathogenic variants of ARSs have been previously associated with peripheral neuropathy and multisystem disease in heterozygotes and homozygotes, respectively. We report seven…

Tags: 2019, Adult, Antonellis Anthony, Baras Aris, Biochemistry & Molecular Biology, Brigatti Karlla W, Carson Vincent J, Catalytic Domain, Child, Demczko Matthew M, Female, Fox Michael D, Furuya Katryn N, gene, Genetic Diseases, Genetic Predisposition to Disease, Genetics & Heredity, Gonzaga-Jauregui Claudia, Griffin Laurie B, Hearing Loss, Heterozygote, Homozygote, Human molecular genetics, Humans, impairment, Inborn, Infant, Jinks Robert N, Kandula Vinay V R, lactic-acidosis, Loss of Function Mutation, Male, Martinez Erick D, mechanisms, Miles Lili, Mutation, myopathy, NEOMED College of Medicine Student, NEOMED Student Publications, Newborn, onset, Overton John D, Pedigree, Phenotype, phenotypic variability, Poskitt Laura, Preschool, Puffenberger Erik G, Radhakrishnan Kadakkal, recessive mutations, Reid Jeffrey G, Sensorineural, September 2019 Update, Severity of Illness Index, Strauss Kevin A, swiss-model, Tyrosine-tRNA Ligase, variant, Wenger Olivia K, Whole Exome Sequencing, Williams Katie B, Yeasts, Yoder Mark A

TRAPPC9: Novel insights into its trafficking and signaling pathways in health and disease (Review).

Trafficking protein particle complex 9 (TRAPPC9) is a protein subunit of the transport protein particle II (TRAPPII), which has been reported to be important in the trafficking of cargo from the endoplasmic reticulum (ER) to the Golgi, and in…

Tags: *Disease Susceptibility, *Signal Transduction, 2018, Animals, Carrier Proteins/chemistry/genetics/*metabolism, Gene Expression Regulation, Humans, Hussein Nazar J, International journal of molecular medicine, Mbimba Thomas, Najeed Ayesha, Protein Binding, Protein Interaction Domains and Motifs, Protein Transport, Safadi Fayez F, Structure-Activity Relationship

Olmesartan Associated Enteropathy: A Rare Underdiagnosed Cause of Diarrhea and Weight Loss.

BACKGROUND Olmesartan, an angiotensin receptor blockade class of antihypertensive medication has recently been associated with a seronegative sprue like enteropathy. Patients typically present with diarrhea and weight loss often prompting exhaustive…

Tags: *Weight Loss, 2019, Antihypertensive Agents/*adverse effects, Colitis, Department of Internal Medicine, Diarrhea/*chemically induced, Gonakoti Sripriya, Humans, Imidazoles/*adverse effects, Khullar Sanjiv, Lymphocytic/*chemically induced, Male, Middle Aged, NEOMED College of Medicine, Rajkumar Aarthi, Tetrazoles/*adverse effects, The American journal of case reports, Vomiting/*chemically induced

Delivery Systems as Vital Tools in Drug Repurposing.

The process of developing an old drug for new indications is now a widely accepted strategy of shortening drug development time, reducing drug costs, and improving drug availability, especially for rare and neglected diseases. In this mini-review, we…

Tags: *Drug Delivery Systems, *Drug Repositioning, 2019, AAPS PharmSciTech, combination drugs, Czech Tori, Department of Pharmaceutical Sciences, Drug Carriers, drug development, Humans, Lalani Reza, nanocarriers, Nanoparticles, NEOMED College of Pharmacy, Oyewumi Moses O, Tissue Distribution

The glycoprotein GPNMB attenuates astrocyte inflammatory responses through the CD44 receptor.

BACKGROUND: Neuroinflammation is one of the hallmarks of neurodegenerative diseases, such as Parkinson's disease (PD). Activation of glial cells, including microglia and astrocytes, is a characteristic of the inflammatory response. Glycoprotein…

Contributions of symptomatic osteoarthritis and physical function to incident cardiovascular disease.

BACKGROUND: Osteoarthritis (OA) is associated with worsening physical function and a high prevalence of comorbid health conditions. In particular, cardiovascular disease (CVD) risk is higher in individuals with OA than the general population.…

The Incidence of Complex Regional Pain Syndrome in Simultaneous Surgical Treatment of Carpal Tunnel Syndrome and Dupuytren Contracture.

BACKGROUND: To determine the incidence of complex regional pain syndrome (CRPS) in the concurrent surgical treatment of Dupuytren contracture (DC) and carpal tunnel syndrome (CTS) through a thorough review of evidence available in the literature.…

Tags: *carpal tunnel, *CRPS, *Dupuytren contracture, 2018, Buller Mitchell, Carpal Tunnel Syndrome/complications/*surgery, Complex Regional Pain Syndromes/*etiology, Dupuytren Contracture/complications/*surgery, Fasciotomy, Hand (New York, N.Y.), Humans, Incidence, Kasdan Morton, Postoperative Complications/*etiology, Schulz Steven, Wilhelmi Bradon J

Interventions That Target Criminogenic Needs for Justice-Involved Persons With Serious Mental Illnesses: A Targeted Service Delivery Approach.

This research describes the development of a targeted service delivery approach that tailors the delivery of interventions that target criminogenic needs to the specific learning and treatment needs of justice-involved people with serious mental…

Tags: 2018, Bonfine Natalie, Community Mental Health Services/*organization & administration, Criminal Law, Criminals/*psychology/statistics & numerical data, criminogenic needs, Department of Family & Community Medicine, Department of Psychiatry, Duda-Banwar Janelle, Farkas Kathleen, Health Services Needs and Demand/*statistics & numerical data, Humans, International journal of offender therapy and comparative criminology, Mental Disorders/psychology/*therapy, mental illness, Mentally Ill Persons/*psychology/statistics & numerical data, NEOMED College of Medicine, recidivism, Wilson Amy Blank

Changing the Channels: Nature's Remote Controlling in Health and Disease.

Tags: *coronary artery disease, *Editorials, *hydrogen peroxide, *potassium channels, *protein kinases, *vasodilation, 2017, Arterioles, Circulation research, Coronary Vessels, Department of Integrative Medical Sciences, Dilatation, Humans, NEOMED College of Medicine, Thodeti Charles K

Adapt or Perish: Updating the Predoctoral Training Model.

Tags: *Curriculum, *graduate education, *mentoring, 2017, Chabowski Dawid, Circulation research, Curriculum/*standards, DelloStritto Daniel, Education, Graduate/*methods, Gutterman David, Humans, Kadlec Andrew, Mentoring/methods, Research Personnel/*standards, Science/*education

The Unraveling of the Matryoshka Doll.

Tags: *chemokines, *exosomes, *heart failure, *Myocardial infarction, *Stem cells, 2017, Adult, Adult Stem Cells/metabolism/*transplantation, Circulation research, Exosomes/genetics/metabolism, Gene Expression, Heart Diseases/physiopathology/*therapy, Humans, MicroRNAs/genetics/metabolism, Penn Marc S, Regenerative Medicine/methods/trends, Stem Cell Transplantation/*methods

Exploring comorbid depression and physical health trajectories: A case-based computational modelling approach.

While comorbid depression/physical health is a major clinical concern, the conventional methods of medicine make it difficult to model the complexities of this relationship. Such challenges include cataloguing multiple trends, developing multiple…

Iatrogenic emergency medicine procedure complications and associated trouble-shooting strategies.

PURPOSE: The purpose of this paper is to provide a consolidated reference for the acute management of selected iatrogenic procedural injuries occurring in the emergency department (ED). DESIGN/METHODOLOGY/APPROACH: A literature search was performed…

Commentary on an Excerpt From The Illness Narratives: Suffering, Healing, and the Human Condition.

Tags: *Medicine in Literature, *Physician-Patient Relations, *Stress, 2017, Academic medicine : journal of the Association of American Medical Colleges, Blackie Michael, Humans, Pain/*psychology, Physicians/*psychology, Psychological

Quinone and nitrofurantoin redox cycling by recombinant cytochrome b5 reductase.

NADH cytochrome b5 reductase mediates electron transfer from NADH to cytochrome b5 utilizing flavin adenine dinucleotide as a redox cofactor. Reduced cytochrome b5 is an important cofactor in many metabolic reactions including cytochrome

Reversal of metabolic disorders by pharmacological activation of bile acid receptors TGR5 and FXR.

OBJECTIVES: Activation of the bile acid (BA) receptors farnesoid X receptor (FXR) or G protein-coupled bile acid receptor (GPBAR1; TGR5) improves metabolic homeostasis. In this study, we aim to determine the impact of pharmacological activation of…

Editorial Comment.

Tags: *Elasticity Imaging Techniques, *Prostatic Neoplasms, 2018, Barr Richard G, Humans, Male, Prospective Studies, The Journal of urology

Glycoprotein Nonmelanoma Clone B Regulates the Crosstalk between Macrophages and Mesenchymal Stem Cells toward Wound Repair.

The process of wound repair requires the coordinated participation of multiple types of cells, which are sequentially recruited during the healing process. In response to tissue injury, both macrophages and mesenchymal stem cells (MSCs) are recruited…

Nrf2/ARE pathway attenuates oxidative and apoptotic response in human osteoarthritis chondrocytes by activating ERK1/2/ELK1-P70S6K-P90RSK signaling axis.

Nrf2, a redox regulated transcription factor, has recently been shown to play a role in cartilage integrity but the mechanism remains largely unknown. Osteoarthritis (OA) is a multifactorial disease in which focal degradation of cartilage occurs.…

The anti-parkinsonian drug zonisamide reduces neuroinflammation: Role of microglial Nav 1.6.

Parkinson's disease (PD), the second most common age-related progressive neurodegenerative disorder, is characterized by dopamine depletion and the loss of dopaminergic (DA) neurons with accompanying neuroinflammation. Zonisamide is…

Exploring the role of YouTube in delivering dementia education to older Chinese.

Tags: *Geriatric Assessment, *Social Media, 2018, Aged, Asian journal of psychiatry, China, Dementia/*psychology, Female, Health Education/*methods, Humans, Internet, Lam Nikki H T, Male, Middle Aged, Woo Benjamin K P

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