Browse Items (332 total)
- Tags: Department of Pharmaceutical Sciences
Gaussian Process Modeling of Protein Turnover.
Tags: *Brain Chemistry, *dynamic proteome, *Gaussian process, *Mass spectrometry, *Ornstein-Uhlenbeck process, *protein degradation rate constant, *protein turnover rate constant, *stable isotope labeling, *stochastic differential equation for protein turnover rate constant, 2016, Animals, Chromatography, Data Interpretation, Department of Pharmaceutical Sciences, Isotope Labeling, Journal of proteome research, Kasumov Takhar, Kinetics, Liquid, Liver/*chemistry, Mass spectrometry, Mice, NEOMED College of Pharmacy, Normal Distribution, Previs Stephen F, Proteins/*metabolism, Proteome/*metabolism, Proteomics/methods, Rahman Mahbubur, Sadygov Rovshan G, Statistical, Stochastic Processes
Results of the promoting effective advance care planning for elders (PEACE) randomized pilot study.
Tags: *Quality of Life, 2014, 80 and over, Activities of Daily Living, advance care planning, Advance Care Planning/*organization & administration, Aged, Albanese Teresa H, Allen Kyle R, Case Management – Methods, Chi Square Test, College of Medicine, Community-Institutional Relations, Comparative Studies, Decision Making, Department of Family & Community Medicine, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Descriptive Statistics, Disease Management, Ertle Denise, Family, Female, Fosnight Susan M, Frail Elderly, Geriatric Assessment/methods, Hazelett Susan E, Health Promotion, Health Resource Utilization, Health Services for the Aged/organization & administration, Home Care Services/*organization & administration, Human, Humans, Interdisciplinary Communication, Kropp Denise J, Long Term Care, Long-Term Care/*organization & administration, Male, Medicaid – Ohio, Moore Pamela S, Multidisciplinary Care Team, NEOMED College of Medicine, NEOMED College of Pharmacy, Ohio, Outcomes (Health Care), Palliative Care, Palliative Care/organization & administration, Patient, Physicians, Pilot Projects, Pilot Studies – Ohio, Population health management, Program Evaluation, Psychological Tests, Quality of Life, Radwany Steven M, Random Assignment, Reference Values, Repeated Measures, Scales, Spiritual Care, T-Tests, Treatment Outcome
Turnover of histones and histone variants in postnatal rat brain: effects of alcohol exposure.
Tags: *2H2O-labeling, *Brain, *Genetic Variation, *Histone, *Mass spectrometry, *Post-translational modifications, *Postnatal alcohol exposure, *Turnover, 2017, Acetylation, Animal, Animals, Cell Proliferation, Clinical epigenetics, Department of Pharmaceutical Sciences, Disease Models, DNA Damage, Epigenesis, Female, Fetal Alcohol Spectrum Disorders/genetics/*metabolism, Genetic, Histones/*genetics/*metabolism, Humans, Kasumov Takhar, Li Ling, NEOMED College of Pharmacy, Post-Translational, Pregnancy, Previs Stephen, Protein Processing, Proteomics/*methods, Rachdaoui Nadia, Rats, Sarkar Dipak, Sprague-Dawley, Willard Belinda
Songling Xuemaikang Capsule inhibits isoproterenol-induced cardiac hypertrophy via CaMKIIdelta and ERK1/2 pathways.
Glaucoma-associated E50K-optineurin mutation impairs mitochondrial-derived vesicle trafficking
Tags: 2019, Chen Charlaine, Department of Pharmaceutical Sciences, Inman Denise M, Investigative ophthalmology & visual science, Journal Article, NEOMED College of Medicine, NEOMED College of Medicine Student, NEOMED College of Pharmacy, NEOMED Student Publications, November 2019 Update, Powers James, Sun Emily, Trautman-Buckley Kayla, Tseng Henry
Assessment of a structured longitudinal professional identity development curriculum for pharmacy students.
Tags: 2018, Boyle Jaclyn, Coffey Cory P, Currents in pharmacy teaching & learning, Department of Family & Community Medicine, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Hoffman Alexander, NEOMED College of Medicine, NEOMED College of Pharmacy, Pokorny Anita, Professional development, Professional identity, Schneider Stacey, Student pharmacist development
Time course and magnitude of alpha-synuclein inclusion formation and nigrostriatal degeneration in the rat model of synucleinopathy triggered by intrastriatal α-synuclein preformed fibrils
Tags: 2019, Alpha-synuclein, Collier Timothy J, Department of Family & Community Medicine, Department of Pharmaceutical Sciences, Duffy Megan F, El-Agnaf Omar M A, Fleming Sheila M, Howe Jacob W, Kanaan Nicholas M, Kemp Christopher J, Levine Nathan, Luk Kelvin C, Miller Kathryn M, Moore Darren J, NEOMED College of Medicine, NEOMED College of Pharmacy, Neurobiology of disease, Parkinson's disease, Patel Pooja, Patterson Joseph R, Paumier Katrina L, Preformed fibrils, September 2019 Update, Sortwell Caryl E, Stoll Anna C, Synucleinopathy
Upregulation of monocarboxylate transporter 2 protects retinal ganglion cells in glaucoma
Tags: 2019, Department of Pharmaceutical Sciences, Harun-Or-Rashid Mohammad, Inman Denise M, Investigative ophthalmology & visual science, Jaboori Assraa Jassim, Journal Article, NEOMED College of Graduate Studies, NEOMED College of Graduate Studies Student, NEOMED Student Publications, November 2019 Update, Pappenhagen Nate
Gelucire-stabilized nanoparticles as a potential DNA delivery system.
Tags: *Gene Transfer Techniques, 2016, Animals, Cationic lipids, Cell Line, Cell Survival/drug effects/physiology, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, DNA/*administration & dosage/chemistry, gene therapy, Hep G2 Cells, Humans, macrophage activation, Macrophages/drug effects/physiology, Mice, Nanoparticles, Nanoparticles/*administration & dosage/chemistry, NEOMED College of Graduate Studies, NEOMED College of Pharmacy, Oyewumi Moses O, Pharmaceutical development and technology, Polyethylene Glycols/*administration & dosage/chemistry, Sadana Prabodh, Transfection, Wehrung Daniel
Osteoactivin (GPNMB) ectodomain protein promotes growth and invasive behavior of human lung cancer cells.
Tags: *Cell Movement, *Cell Proliferation, 2016, Animals, Apoptosis, Biomarkers, Carcinoma, Cell Adhesion, Cultured, Department of Anatomy & Neurobiology, Department of Pharmaceutical Sciences, Female, GPNMB, Humans, integrin, Lung cancer, Lung Neoplasms/metabolism/*pathology, Manickavasagam Dharani, Membrane Glycoproteins/*metabolism, Mice, Moussa Fouad M, NEOMED College of Medicine, NEOMED College of Pharmacy, Neoplasm Invasiveness, Non-Small-Cell Lung/metabolism/*pathology, Novak Kimberly, NSCLC, Nude, Oncotarget, Oyewumi Moses O, Paulic Nikola, Protein Domains, Safadi Fayez F, Sondag Gregory R, Tumor Cells, Tumor/*metabolism, Wehrung Daniel, Xenograft Model Antitumor Assays
Nano-microparticles as immune adjuvants: correlating particle sizes and the resultant immune responses.
Tags: *Microspheres, *Nanoparticles, 2010, Adaptive Immunity, Adjuvants, Animals, Cui Zhengrong, Department of Pharmaceutical Sciences, Expert review of vaccines, Humans, Immunity, Immunologic/*pharmacology, Innate, Kumar Amit, NEOMED College of Pharmacy, Oyewumi Moses O, Particle Size, Vaccines/*immunology
Emerging lung cancer therapeutic targets based on the pathogenesis of bone metastases.
Screening and identification of novel compounds with potential anti-proliferative effects on gallium-resistant lung cancer through an AXL kinase pathway.
Tags: 2014, Alazizi Adnan, Antineoplastic Agents/chemical synthesis/chemistry/*pharmacology, Antitumor, AXL, Bioorganic & medicinal chemistry letters, Cell Line, Cell Proliferation/drug effects, Cell Survival/drug effects, Department of Pharmaceutical Sciences, Dose-Response Relationship, Drug, Drug Resistance, Drug Screening Assays, Gallium, Gallium-resistance, Gallium/pharmacology, Geldenhuys Werner J, Humans, Lin Li, Liva Sophia, Lung cancer, Lung Neoplasms/drug therapy/*enzymology/*pathology, Molecular Structure, Naphthalenes/chemistry/*pharmacology, NEOMED College of Pharmacy, Neoplasm/drug effects, Oyewumi Moses O, Proto-Oncogene Proteins/*antagonists & inhibitors/metabolism, Pyrazoles/chemistry/*pharmacology, Quinolines/chemistry/*pharmacology, Receptor Protein-Tyrosine Kinases/*antagonists & inhibitors/metabolism, Structure-Activity Relationship, Tetrazoles/chemistry/*pharmacology, Tumor, Virtual screening
Overcoming missed opportunities in diabetes management to improve outcomes for hospitalized patients with diabetes.
Tags: 2018, Aged, Blood Glucose/*metabolism, Clough Lynn, Cohort Studies, Cudnik Michelle L, Department of Internal Medicine, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Diabetes Mellitus, Diabetes research and clinical practice, Elavsky Megan, Female, Glycated Hemoglobin A/*metabolism, Hospitalization, Humans, Kunz Jason, Male, Middle Aged, NEOMED College of Medicine, NEOMED College of Pharmacy, Oravec Michael, Retrospective Studies, Salem James, Treatment Outcome, Type 2/*drug therapy, Woods Robert
Requisite Role of Kv1.5 Channels in Coronary Metabolic Dilation.
Tags: 129 Strain, 2015, Animals, Bardakjian Raffi, Bratz Ian, Cardiac function, Chilian William M, Circulation research, contrast echocardiography, Coronary Circulation/*physiology, Coronary Vessels/*metabolism, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Enrick Molly, Fu Frances Kwan, Graham Jacqueline, Hakobyan Tatevik, Hou Huagang, Hydrogen peroxide, Inbred C57BL, ion channel, Janota Danielle, Khan Nadeem, Kmetz John, Knockout, Kolz Christopher, Kuppusamy Periannan, Kv1.5 Potassium Channel/*physiology, Lindner Jonathan R, Logan Suzanna, Luli Jordan, Mice, Muscle, Nagane Masaki, NEOMED College of Medicine, NEOMED College of Pharmacy, Ohanyan Vahagn, Oyewumi Moses O, Smooth, Transgenic, Transgenic mice, Vascular/*metabolism, vasodilation, Vasodilation/*physiology, voltage-gated potassium channels, Yin Liya
LPS-TLR4 Pathway Mediates Ductular Cell Expansion in Alcoholic Hepatitis.
Tags: 2016, Affo Silvia, Alcoholic/*immunology, Altamirano Jose, Animals, Arroyo Vicente, Bataller Ramon, Caballeria Juan, Cell Proliferation, Cells, Chen Jiegen, Collagen/genetics/metabolism, Common/*pathology, Crews Fulton, Cultured, Department of Pharmaceutical Sciences, Dumitru Raluca, Female, Gene Expression Profiling, Gene Expression Regulation, Gines Pere, Hepatic Duct, Hepatitis, Hepatocytes/*metabolism/pathology, Humans, Inbred BALB C, Keratins, Knockout, Lipopolysaccharides/metabolism, Lozano Juan Jose, Male, Matsushita Hiroshi, Mice, Middle Aged, Morales-Ibanez Oriol, NEOMED College of Pharmacy, Odena Gemma, Rautou Pierre-Emmanuel, Rodrigo-Torres Daniel, Sancho-Bru Pau, Scientific reports, Seki Ekihiro, Signal Transduction, Toll-Like Receptor 4/genetics/*metabolism, Type I/genetics/*metabolism, Valla Dominique, You Min, Zou Jian
Is the Public Service Loan Forgiveness program right for you?
Tags: 2017, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, debt, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Financial – United States, loan forgiveness, loan repayment, NEOMED College of Pharmacy, Notareschi Vincent, Program Evaluation, student loan, Training Support, Ulbrich Timothy R, United States
Injury-induced gp130 cytokine signaling in peripheral ganglia is reduced in diabetes mellitus.
Tags: *Axon regeneration, *Axotomy, *Diabetes, *Neuropathy, *Peripheral nervous system, 2017, Animal, Animals, Antibiotics, Antineoplastic/toxicity, Blood Glucose/drug effects, Body Weight/drug effects, Crish Samuel D, Cytokine Receptor gp130/genetics/*metabolism, Cytokines/metabolism, DeFrancesco Alicia, Department of Pharmaceutical Sciences, Diabetes Mellitus, Disease Models, Experimental neurology, Experimental/chemically induced/complications/*pathology, Fasting/blood, Filous Angela R, Gene Expression Regulation/*physiology, Hyperalgesia/etiology, Hyperglycemia/etiology, Inbred C57BL, Lindborg Jane A, Male, Malhotra Nisha A, Mice, NEOMED College of Pharmacy, Nerve Degeneration/*etiology/pathology, Nerve Tissue Proteins/metabolism, Niemi Jon P, Pain Measurement, Signal Transduction/drug effects/*physiology, Streptozocin/toxicity, Superior Cervical Ganglion/drug effects/*metabolism, Sweating/drug effects, Wilson Gina N, Zhou Bowen, Zigmond Richard E
Time to get Personal: A Framework for Personalized Targeting of Oxidative Stress in Neurotoxicity and Neurodegenerative Disease.
Epigenetic regulation of astrocyte function in neuroinflammation and neurodegeneration.
Tags: *Astrocyte, *DNA methylation, *Epigenesis, *Epigenetic, *Histone, *neurodegeneration, *Neuroinflammation, 2018, Acetylation, Alzheimer Disease/genetics/pathology, Animals, Astrocytes/*cytology/immunology, Biochimica et biophysica acta. Molecular basis of disease, Cell Differentiation, Department of Pharmaceutical Sciences, DNA Methylation, Genetic, Histones/metabolism, Humans, Inflammation/*pathology, Methylation, MicroRNAs/metabolism, Neal Matthew, NEOMED College of Pharmacy, Neurodegenerative Diseases/genetics/*pathology, Neuroglia/metabolism, Neurons/immunology, Parkinson Disease/genetics/pathology, Richardson Jason R
Pharmacological inhibition of CSF1R by GW2580 reduces microglial proliferation and is protective against neuroinflammation and dopaminergic neurodegeneration.
Tags: 2020, Alam Gelareh, Beier Eric E, Boyle Alexa M, Budge Kevin M, Department of Pharmaceutical Sciences, Faseb Journal, Fleming Sheila M, January 2020 Update, Journal Article, Kim Chunki, Microglia, Neal Matthew L, NEOMED College of Pharmacy, Neuroprotection, Parkinson's disease, proliferation, Richardson Jason R, Wu Long‐Jun
The glycoprotein GPNMB attenuates astrocyte inflammatory responses through the CD44 receptor.
Tags: 2018, Astrocyte, Boyle Alexa M, Budge Kevin M, CD44, Department of Anatomy & Neurobiology, Department of Pharmaceutical Sciences, GPNMB, Journal of neuroinflammation, Neal Matthew L, NEOMED College of Medicine, NEOMED College of Pharmacy, Neuroinflammation, Parkinson's disease, Richardson Jason R, Safadi Fayez F
Novel compounds that target lipoprotein lipase and mediate growth arrest in acute lymphoblastic leukemia.
Tags: *Acute lymphoblastic leukemia, *Cancer, *Co-culture model, *Lipids, *Lipoprotein lipase, *Metabolism, 2018, Amides/chemistry/metabolism/pharmacology, Antineoplastic Agents/*chemistry/metabolism/pharmacology, Binding Sites, Bioorganic & medicinal chemistry letters, Cell Line, Cell Proliferation/drug effects, Coculture Techniques, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Dyslipidemias/complications/metabolism/pathology, Geldenhuys Werner J, Gibson Laura F, Humans, Lipoprotein Lipase/antagonists & inhibitors/*metabolism, Mesenchymal Stem Cells/cytology/metabolism, Molecular Docking Simulation, Nair Rajesh R, NEOMED College of Graduate Studies, NEOMED College of Pharmacy, Piktel Debbie, Precursor Cell Lymphoblastic Leukemia-Lymphoma/complications/metabolism/pathology, Protein Binding, Protein Structure, Sadana Prabodh, Serum Albumin/chemistry/metabolism, Tertiary, Tumor
Astrocytic changes with aging and Alzheimer's disease-type pathology in chimpanzees
Tags: 2019, Aging, Alzheimer's disease, Astrocytes, cerebral cortex, chimpanzees, Department of Pharmaceutical Sciences, Edler Melissa K, Ely John J, Erwin Joseph M, Hippocampus, Hof Patrick R, Hopkins William D, June 2019 Update, Mufson Elliott J, Munger Emily L, NEOMED College of Pharmacy, Perl Daniel P, prefrontal cortex, Raghanti Mary Ann, RRID: AB2109645, RRID: AB223647, RRID: AB2313952, RRID: AB2314223, Sherwood Chet C, Stereology, The Journal of comparative neurology
Relationships between Very Low-Density Lipoproteins-Ceramides, -Diacylglycerols, and -Triacylglycerols in Insulin-Resistant Men.
Tags: 2020, Biomarkers, Ceramides, Department of Pharmaceutical Sciences, Disease, Gaballah Ayman, Garrett Timothy J, Humans, Inflammation, journalArticle, June 2020 Update II, Kasumov Takhar, Kinetics, LDL, Lipids, Manrique-Acevedo Camila, Metabolic syndrome, Mucinski Justine M, NAFLD, NEOMED College of Pharmacy, obese men, Parks Elizabeth J, secretion, sphingolipids, VLDL
Utilization of a reminder mailing to improve blood glucose log reporting in an outpatient diabetes clinic.
Tags: 2012, Adult, Aged, Ambulatory Care – Methods, American journal of therapeutics, Blood Glucose Self-Monitoring – Methods, Chomo DL, Department of Family & Community Medicine, Department of Internal Medicine, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Diabetes Mellitus – Drug Therapy, Dillon ML, Female, Frazee L A, Human, Hypoglycemic Agents – Therapeutic Use, Mail, Male, Middle Age, Moorman JM, Myers NA, NEOMED College of Medicine, NEOMED College of Pharmacy, Patient Compliance, Prospective Studies, Reminder Systems, Retrospective Design
Long bone histomorphogenesis of the naked mole‐rat: Histodiversity and intraspecific variation.
Tags: 2021, Bennett NC, Body Temperature, bone growth, bone microstructure, bone modeling, Chinsamy A, Dengler‐Crish CM, Department of Pharmaceutical Sciences, endosteal bone, Heterocephalus glaber, hypothermia, Journal of anatomy, journalArticle, July 2021 List, lamellar bone, lamellar‐zonal bone, long bone growth, Montoya‐Sanhueza G, Morphogenesis, NAKED mole rat, NEOMED College of Medicine, ontogeny, Oosthuizen MK, Periosteum, POLARIZATION microscopy, STRAINS & stresses (Mechanics)
Bone remodeling in the longest living rodent, the naked mole‐rat: Interelement variation and the effects of reproduction.
Bone remodeling in the longest living rodent, the naked mole-rat: Interelement variation and the effects of reproduction.
Tags: 2021, Bennett NC, Bone resorption, Chinsamy A, Dengler-Crish CM, Department of Pharmaceutical Sciences, February 2021 List, Female breeder, Haversian systems, Heterocephalus glaber, Journal of anatomy, journalArticle, Montoya-Sanhueza G, NEOMED College of Medicine, Oosthuizen MK, Secondary osteons, Secondary reconstruction
Long bone histomorphogenesis of the naked mole-rat: Histodiversity and intraspecific variation.
Tags: 2020, Bennett NC, bone microstructure, bone modeling, Chinsamy A, Dengler-Crish CM, Department of Pharmaceutical Sciences, endosteal bone, Heterocephalus glaber, January 2021 List, Journal of anatomy, journalArticle, lamellar bone, lamellar-zonal bone, lamellar‐, long bone growth, Montoya-Sanhueza G, NEOMED College of Pharmacy, Oosthuizen MK, zonal bone
Transport of a manganese/zinc ethylene-bis-dithiocarbamate fungicide may involve pre-synaptic dopaminergic transporters
Tags: 2018, antidepressant, Bailey A, Barnett R, C. elegans, caenorhabditis-elegans, Corona C, costa-rica, degeneration, Department of Pharmaceutical Sciences, exposure, Fitsanakis V A, Frye R, infants environmental-health, Journal Article or Conference Abstract Publication, leads, Mancozeb, Manzate, Mn/Zn ethylene-bis-dithiocarbamate, Montgomery K, NEOMED College of Pharmacy, Neurosciences & Neurology, Neurotoxicology and teratology, Neurotransmitter transporters, NEUROTRANSMITTERS, parkinsons-disease, pregnant-women, Toxicology
Monitoring the synthesis of biomolecules using mass spectrometry.
Tags: 2016, biosynthesis, Department of Pharmaceutical Sciences, Deuterium Oxide/chemistry, deuterium water, flux analysis, Kasumov Takhar, Kinetics, Macromolecular Substances/*chemistry/*metabolism, Mass spectrometry, Mass Spectrometry/*methods, Metabolomics, Miyagi Masaru, NEOMED College of Pharmacy, Philosophical transactions. Series A, Mathematical, physical, and engineering sciences, proteomics
Sex differences in cognitive performance and alcohol consumption in High Alcohol-Drinking (HAD-1) rats
Tags: 2019, Alcohol use disorders, Attention, Behavioural brain research, Bell R L, Department of Pharmaceutical Sciences, Duvauchelle C L, Exploratory behavior, Fleming S M, January 2020 Update, Journal Article, Maddox W T, Martinez A, Mittal N, NEOMED College of Pharmacy, Novel object recognition, Object recognition test, Schallert T, Selectively bred high alcohol-drinking rats, Thakore N
Engineering triiodothyronine (T3) nanoparticle for use in ischemic brain stroke.
Tags: 2013, Blood-brain barrier, Brain stroke, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Drug delivery and translational research, Geldenhuys Werner J, Mdzinarishvili Alexander, Nanoparticles, NEOMED College of Graduate Studies, NEOMED College of Pharmacy, Neuroprotection, Sadana Prabodh, Sutariya Vijaykumar, Talasila Phani K, Thyroid hormone
Stable isotope-based flux studies in nonalcoholic fatty liver disease.
Tags: *Citric acid cycle, *Fatty acid oxidation, *Fibrosis, *NAFLD, *Oxidative Stress, *Stable isotopes, 2018, Animals, Department of Pharmaceutical Sciences, Humans, Isotopes/metabolism, Kasumov Takhar, Mass Spectrometry/*methods, McCullough Arthur, NEOMED College of Pharmacy, Non-alcoholic Fatty Liver Disease/*metabolism, Pharmacology & therapeutics, Previs Stephen
HDL Flux is Higher in Patients with Nonalcoholic Fatty Liver Disease
Tags: 2019, American journal of physiology. Endocrinology and metabolism, Dasarathy Jaividhya, Dasarathy Srinivasan, Department of Pharmaceutical Sciences, haevy water, HDL, Ilchenko Serguei, Kasumov Takhar, Kim Chunki, Lee Kwangwon, Lorkowski Shuhui W, McCullough Arthur, NAFLD, NASH, NEOMED College of Pharmacy, October 2019 Update, Osme Abdullah, Previs Stephen F, proteomics, Smith Jonathan D