Browse Items · NEOMED Bibliography Database

Left ventricular pseudoaneurysm presenting twenty-eight months after myocardial infarction. A case report.

Tags: 1997, Angiology, Coronary Aneurysm/diagnosis/*etiology, Department of Internal Medicine, Female, Heart Ventricles, Humans, Magnetic Resonance Imaging/methods, Martin R, Middle Aged, Myocardial Infarction/*complications, NEOMED College of Medicine, Ognibene A, Smith A S, Tegtmeier T, Time Factors

Early upregulation of myocardial CXCR4 expression is critical for dimethyloxalylglycine-induced cardiac improvement in acute myocardial infarction.

The stromal cell-derived factor-1 (SDF-1):CXCR4 is important in myocardial repair. In this study we tested the hypothesis that early upregulation of cardiomyocyte CXCR4 (CM-CXCR4) at a time of high myocardial SDF-1 expression could be a strategy to…

Tags: 2016, alpha Subunit/metabolism, American journal of physiology. Heart and circulatory physiology, Amino Acids, Animal, Animals, Apoptosis/drug effects, Cardiotonic Agents/*pharmacology, Cell Hypoxia, Cell Line, Chilian William M, CXCR4/deficiency/genetics/*metabolism, Department of Integrative Medical Sciences, Dicarboxylic/*pharmacology, Disease Models, Dong Feng, Enzyme Inhibitors/pharmacology, Forudi Farhad, hypoxia, Hypoxia-Inducible Factor 1, Hypoxia-Inducible Factor-Proline Dioxygenases/antagonists & inhibitors/metabolism, Inbred C57BL, Kiedrowski Matthew, Knockout, Left/*drug effects, Mayorga Mari, Mice, myocardial infarction, Myocardial Infarction/*drug therapy/genetics/metabolism/pathology/physiopathology, Myocardium/*metabolism/pathology, NEOMED College of Medicine, Penn Marc S, Rats, Receptors, Recovery of Function, Shamhart Patricia, Signal Transduction/drug effects, stem cells, Stem Cells/drug effects/metabolism, Stroke Volume/drug effects, Time Factors, Up-Regulation, Ventricular Function, Weber Kristal

Effect of digital rectal examination (and ejaculation) on serum prostate-specific antigen after twenty-four hours. A randomized, prospective study.

The purpose of this randomized, controlled, clinical trial was to determine the effect of the digital rectal examination (DRE) on the prostate-specific antigen (PSA) serum levels in view of conflicting literature reports and screening methods and…

Tags: *Palpation, 1993, 80 and over, Adult, Aged, Ejaculation, Geller L, Gerson L W, Humans, Male, McAleer J K, McMahon D, Middle Aged, Prospective Studies, Prostate-Specific Antigen/*blood, Rectum, Time Factors, Urology

Physician assessment of patient motivation: influence on disposition for follow-up care.

This study of 3,318 outpatient visits evaluated the influence of the physician-assessed level of patient motivation on the level of physician involvement in follow-up care. Data collected included patient demographics, health risk factors,…

Awake aortic aneurysm repair in patients with severe pulmonary disease.

BACKGROUND: We report the use of retroperitoneal aortic aneurysm repair utilizing exclusive regional anesthesia (no intubation or inhalation anesthetic) in high pulmonary risk patients. METHODS: Six patients were retrospectively reviewed. Pulmonary…

Tags: *Consciousness, 1999, Abdominal/*surgery, Administration, Aged, Albuterol/administration & dosage/therapeutic use, American journal of surgery, Anesthesia, Aortic Aneurysm, Blood Loss, Bronchodilator Agents/administration & dosage/therapeutic use, Critical Care, Epidural, Forced Expiratory Volume/physiology, General, Hirko M K, Home Care Services, Hospitalization, Humans, Hypnotics and Sedatives/administration & dosage, Iliac Aneurysm/*surgery, Inhalation, Intravenous, Koler A J, Labat G C, Length of Stay, Lung Diseases/*complications/drug therapy/therapy, McGregor W E, Oxygen Inhalation Therapy, Perni V, Retroperitoneal Space, Retrospective Studies, Risk Factors, Rubin J R, Safety, Steroids/administration & dosage/therapeutic use, Surgical, Theophylline/administration & dosage/therapeutic use, Time Factors, Vital Capacity/physiology

Expression of alpha-cardiac myosin heavy chain in normal and denervated rat muscle spindles.

Whether any fibers in rat hindlimb muscles express alpha-cardiac myosin heavy chain (MHC) is uncertain. Expression of alpha-cardiac MHC mRNA and the polypeptide for which it codes were examined in control and denervated rat muscle spindles using in…

Tags: 1995, Animals, Denervation, In Situ Hybridization, McWhorter D L, Messenger/metabolism, Muscle Spindles/*metabolism/physiology, Myocardium/*metabolism, Myosin Heavy Chains/*metabolism, Neuroscience letters, Rats, RNA, Signs S A, Sprague-Dawley, Time Factors, Walro J M, Wang J

Long-Term Evaluation of Eyebrow Soft Tissue Expansion in Thyroid Eye Disease.

PURPOSE: To evaluate the long-term transformation of lateral eyebrow soft tissue in a group of patients with known thyroid eye disease. METHODS: A retrospective review of all patients with a known diagnosis of thyroid eye disease with clinical photos…

Tags: 2016, Eyebrows/*diagnostic imaging, Eyelids/*surgery, Female, Follow-Up Studies, Goldberg Robert A, Graves Ophthalmopathy/diagnosis/*surgery, Humans, Male, Middle Aged, Moore Grant H, Ophthalmic plastic and reconstructive surgery, Retrospective Studies, Rootman Dan B, Time Factors, Tissue Expansion/*methods, Yeganeh Amir

Isolation of canine coronary sinus musculature from the atria by radiofrequency catheter ablation prevents induction of atrial fibrillation.

BACKGROUND: The junction between the coronary sinus (CS) musculature and both atria contributes to initiation of atrial tachyarrhythmias. The current study investigated the effects of CS isolation from the atria by radiofrequency catheter ablation on…

Roles of inhibition in creating complex auditory responses in the inferior colliculus: facilitated combination-sensitive neurons.

We studied roles of inhibition on temporally sensitive facilitation in combination-sensitive neurons from the mustached bat's inferior colliculus (IC). In these integrative neurons, excitatory responses to best frequency (BF) tones are enhanced by…

The modulation of long-term potentiation by delta-9-tetrahydrocannabinol in the rat hippocampus, in vitro.

The duration of long-term potentiation (LTP) of the CA1 evoked field potential in rat hippocampal slices was significantly modulated by pre-treatment of slices with delta-9-tetrahydrocannabinol (THC) added to the incubation media. The three THC doses…

Tags: 1987, Animals, Brain research bulletin, Dronabinol/*pharmacology, Evoked Potentials/drug effects, Hippocampus/*drug effects/physiology, In Vitro Techniques, Kinetics, Male, Nowicky A V, Pyramidal Tracts/drug effects/physiology, Rats, Teyler T J, Time Factors, Vardaris R M

The presence of extracellular matrix alters the chondrocyte response to endoplasmic reticulum stress.

The objective of this study was to test the hypothesis that extracellular matrix (ECM) would alter the endoplasmic reticulum (ER) stress response of chondrocytes. Chondrocytes were isolated from calf knees and maintained in monolayer culture or…

Uncovering tinea incognito. Topical corticosteroids can mask typical features of ringworm.

Reversal of antiplatelet therapy in traumatic intracranial hemorrhage: Does timing matter?

Reversal of antiplatelet therapy with platelet transfusion in traumatic intracranial hemorrhage remains controversial. Several studies have examined this topic but few have investigated whether the timing of transfusion affects outcomes. Patients…

Estrogen receptor-alpha and neural circuits to the spinal cord during pregnancy.

Estrogen receptor immunoreactivity and mRNAs are present in spinal cord neurons in locations that are associated with sensory and autonomic innervation of female reproductive organs. The present study was undertaken to examine the expression of…

Expression of pituitary adenylate cyclase activating peptide in the uterine cervix, lumbosacral dorsal root ganglia and spinal cord of rats during pregnancy.

The uterine cervix is highly innervated by the sensory nerves containing neuropeptides which change during pregnancy and are regulated, in part, by estrogen. These neuropeptides act as transmitters both in the spinal cord and cervix. The present…

Keloid treatment: is there a role for acellular human dermis (Alloderm)?

BACKGROUND: Keloid management is faced with high recurrence rates. Keloid fibroblasts lack the normal negative feedback mechanism resulting in an exuberant scar formation. Alloderm doesn't undergo the same proliferative process as keloidal scar…

Acute exercise enhances nitric oxide modulation of vascular response to phenylephrine.

The influence of the release of endothelium-derived nitric oxide (NO) on the vasoconstrictor response to phenylephrine (PE) was evaluated before and after a single bout of dynamic exercise. Each rat ran on a motor-driven treadmill at

Delayed presentation of an inflammatory polyp following colonic ischemia.

Inflammatory polyps are usually associated with inflammatory bowel disease. The majority of these lesions are asymptomatic, however, they may be a source of obstruction or hemorrhage. These polyps represent re-epithelialization of the damaged colonic…

Tags: 1993, Aged, Colitis/*etiology/pathology/surgery, Colon/*blood supply, Colonic Polyps/diagnosis/*etiology/pathology/surgery, Colonoscopy, Female, Hlivko T J, Humans, Ischemia/*complications, Pidala M J, Slezak F A, The American surgeon, Time Factors

Trauma attending in the resuscitation room: does it affect outcome?

Although there are no Class I data supporting the regionalization of trauma care the consensus is that trauma centers decrease morbidity and mortality. However, the controversy continues over whether trauma surgeons should be in-house or take call…

Activation and circuitry of uterine-cervix-related neurons in the lumbosacral dorsal root ganglia and spinal cord at parturition.

Stimulation of the uterine cervix at parturition activates neural circuits involving primary sensory nerves and supraspinally projecting neurons of the lumbosacral spinal cord, resulting in output of hypothalamic neurohormones. Dorsal root ganglia…

Mild acidic pH inhibition of the major pathway of herpes simplex virus entry into HEp-2 cells.

Penetration of the KOS strain of herpes simplex virus type 1 (HSV-1) and the MS and 333 strains of herpes simplex virus type 2 (HSV-2) into HEp-2 cells at pH 6.3 was at least 100-fold less efficient than at pH 7.4. Penetration of two low passage…

Comparative antiplatelet activity of COX1 NSAIDS versus aspirin, encompassing regimen simplification and gastroprotection: a call for a controlled study.

This study was conducted to assess the feasibility of COX1 NSAID substitution for aspirin for preventative therapy related to circulating anticoagulants, as manifest by inhibition of platelet aggregation. There was no difference in platelet…

Functional outcome after anal sphincter injury and treatment with mesenchymal stem cells.

This research demonstrates the regenerative effects of mesenchymal stem cells (MSCs) on the injured anal sphincter by comparing anal sphincter pressures following intramuscular and serial intravascular MSC infusion in a rat model of anal sphincter…

Ethanol-produced interoceptive stimuli are time dependent in selectively bred HAS and LAS rats.

Fourteenth generation high alcohol-sensitive (HAS) and low alcohol-sensitive (LAS) rats were trained to discriminate the effects of 600 mg/kg intraperitoneally administered ethanol from its vehicle at 6 and 30 min postadministration. Each of the…

Tags: *Discrimination Learning, 1992, Alcohol (Fayetteville, N.Y.), Animals, Dose-Response Relationship, Drug, Drug Tolerance, Ethanol/administration & dosage/*pharmacology, Male, Rats, Schechter M D, Time Factors

Drug-drug discrimination: stimulus properties of drugs of abuse upon a serotonergic-dopaminergic continuum.

Ten male N/Nih rats were trained to discriminate between the interoceptive cues produced by the purportedly dopaminergically-mediated drug d-amphetamine at 0.4 mg/kg intraperitoneally administered 20 min prior to training and those produced by the…

Serotonergic-dopaminergic mediation of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy").

A series of three experiments were conducted to investigate the possible serotonergic and dopaminergic mediation of the discriminative stimulus properties of the "designer" drug MDMA. In Experiment 1, rats trained to discriminate 1.5 mg/kg (+/-)-MDMA…

Temporal parameters of cathinone, amphetamine and cocaine.

Rats were trained to discriminate intraperitoneally administered 0.8 mg/kg

Tags: 1989, Alkaloids/*pharmacology, Amphetamines/*pharmacology, Animals, Cocaine/*pharmacology, Conditioning, Discrimination (Psychology)/*drug effects, Inbred Strains, Male, Operant/*drug effects, Pharmacology, biochemistry, and behavior, Rats, Schechter M D, Task Performance and Analysis, Time Factors

Time-dependent effect of ethanol upon discrimination behavior.

The discriminative stimulus properties produced by ethanol were employed to demonstrate differences in discriminative performance over time in rats trained at different postinjection times. Thus, one group of rats was trained to discriminate between…

Tags: 1989, Alcohol (Fayetteville, N.Y.), Animals, Discrimination (Psychology)/*drug effects, Dose-Response Relationship, Drug, Ethanol/*pharmacology, Inbred Strains, Male, Rats, Schechter M D, Time Factors

The anabolic effects of vitamin D-binding protein-macrophage activating factor (DBP-MAF) and a novel small peptide on bone.

Vitamin D-binding protein-macrophage activating factor (DBP-MAF) has previously been shown to stimulate bone resorption and correct the skeletal defects associated with osteopetrosis in two nonallelic mutations in rats. This same protein and a small…

Quality Metrics in Neonatal and Pediatric Critical Care Transport: A National Delphi Project.

OBJECTIVES: The transport of neonatal and pediatric patients to tertiary care facilities for specialized care demands monitoring the quality of care delivered during transport and its impact on patient outcomes. In 2011, pediatric transport teams in…

Tags: *Delphi Technique, 2015, Airway Management – Standards, Airway Management/standards, Benchmarking, Bigham Michael T, Clinical Indicators, Critical Care – Standards, Critical Care Family Needs Inventory, Critical Care/*standards, Delphi Technique, Health Care, Hospitals, Humans, Insoft Robert M, Meyer Keith, Multidisciplinary Care Team – Standards, Ohio, Outcome and Process Assessment (Health Care), Outcomes (Health Care), Patient Care Team/standards, Patient Safety – Standards, Patient Safety/standards, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, Pediatrics – Standards, Pediatrics/*standards, Quality Indicators, Quality of Health Care – Standards, Quality of Health Care/*standards, Schoettker Pamela J, Schwartz Hamilton P, Special, Tertiary Care Centers, Time Factors, Transportation of Patients – Standards, Transportation of Patients/*standards, Trautman Michael S

Daily spontaneous running did not alter vagal afferent reactivity.

Exercise training alters the cardiopulmonary baroreflex regulation of the circulation; however, the mechanisms responsible are unknown. One possibility is an enhanced afferent response to cardiopulmonary stimulation. We therefore tested the…

Serotonergic involvement in the regulation of prolactin and vasoactive intestinal peptide mRNA expression in the rat anterior pituitary.

These studies examined the contribution of serotonin (5-HT) to the control of prolactin (PRL) and vasoactive intestinal peptide (VIP) messenger RNA expression in rat anterior pituitary. Daily injection of rats with the biosynthetic precursor to…

Pregnancy zone protein is a carrier and modulator of placental protein-14 in

A successful pregnancy can only occur when the maternal immune system fails to attack the allogeneic fetus. Two plasma proteins with described immunoregulatory activities, pregnancy zone protein (PZP) and placental protein-14 (PP14; also known as…

Relationship between breast cancer and meningioma.

Several authors have suggested the existence of a relationship between breast cancer and meningioma occurring in the same patient. I describe four patients who had both of these neoplasms and present findings that dispute the implied relationship…

Tags: 1992, Aged, Breast Neoplasms/*diagnosis, Carcinoma, Female, Humans, Intraductal, Meningeal Neoplasms/*diagnosis, Meningioma/*diagnosis, Middle Aged, Neoplasms, Noninfiltrating/*diagnosis, Ovarian Neoplasms/diagnosis, Second Primary/*diagnosis, Smith-Behn J, Southern medical journal, Time Factors

A Prospero-related homeodomain protein is a novel co-regulator of hepatocyte nuclear factor 4alpha that regulates the cholesterol 7alpha-hydroxylase gene.

Prox1, an early specific marker for developing liver and pancreas in foregut endoderm has recently been shown to interact with alpha-fetoprotein transcription factor and repress cholesterol 7alpha-hydroxylase (CYP7A1) gene transcription. Using a…

Tags: *Gene Expression Regulation, 2006, Aged, Amino Acid Motifs, Bile Acids and Salts/metabolism, Cell Line, Cell Nucleus/metabolism, Cells, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*chemistry/*genetics, Cultured/metabolism, Department of Integrative Medical Sciences, Enzymologic, Female, Genes, Genetic, Gluconeogenesis, Glutathione Transferase/metabolism, Hepatocyte Nuclear Factor 4/metabolism/*physiology, Hepatocytes/metabolism, Homeodomain Proteins/metabolism/*physiology, Humans, Immunoprecipitation, Li Tiangang, Liver/metabolism, Luciferases/metabolism, Male, Messenger/metabolism, Middle Aged, NEOMED College of Medicine, Phosphoenolpyruvate Carboxykinase (ATP)/metabolism, Plasmids/metabolism, Protein Structure, Reporter, Response Elements, Reverse Transcriptase Polymerase Chain Reaction, RNA, Small Interfering/metabolism, Song Kwang-Hoon, Tertiary, The Journal of biological chemistry, Time Factors, Transcription, Transcriptional Activation, Transfection, Tumor Suppressor Proteins, Two-Hybrid System Techniques

Acute and subchronic effects of methylenedioxymethamphetamine [(+/-)MDMA] on locomotion and serotonin syndrome behavior in the rat.

Specific behaviors comprising the serotonin syndrome (low body posture, forepaw treading, headweaving) and the autonomic signs of piloerection and salivation were determined and analyzed with locomotor activity in response to MDMA at three doses…

Thermoreversible gel for delivery of activin receptor-like kinase 5 inhibitor

The purpose of this study is to investigate a thermoreversible gel using Pluronic

Tags: *Drug Delivery Systems, 2013, Animal, Animals, Benzodioxoles/*administration & dosage/pharmacokinetics/toxicity, Bhatia Deepak, Body Temperature, Delayed-Action Preparations, Disease Models, Drug Carriers/chemistry/toxicity, Fibroblasts/drug effects/metabolism, Filtering Surgery/*methods, Geldenhuys Werner, Gels, Glaucoma/*surgery, Imidazoles/*administration & dosage/pharmacokinetics/toxicity, Miladore Nicholas, Nakamura Hiroshi, Pharmaceutical development and technology, Poloxamer/chemistry/toxicity, Protein-Serine-Threonine Kinases/antagonists & inhibitors, Pyridines/*administration & dosage/pharmacokinetics/toxicity, Rabbits, Receptor, Receptors, Sutariya Vijaykumar, Temperature, Time Factors, Transforming Growth Factor beta/antagonists & inhibitors, Transforming Growth Factor-beta Type I, Viscosity, Wehrung Daniel

Tags: 2008, American journal of orthopedics (Belle Mead, N.J.), Burns/*complications, Carcinoma, Humans, Male, Middle Aged, Scharschmidt Tom, Skin Neoplasms/*etiology/surgery, Skin Ulcer/*etiology/surgery, Squamous Cell/*etiology/surgery, Tank Jason, Time Factors, Weiner Scott D

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