Browse Items (215 total)
- Tags: Receptors
Identification of novel pathways that control farnesoid X receptor-mediated hypocholesterolemia.
Tags: 2010, Absorption, Anderson Jody, Animals, Biological, Cell Line, Cholesterol/*metabolism, Class B/*genetics/metabolism, Coronary Disease/metabolism, Cytoplasmic and Nuclear/*metabolism, Department of Integrative Medical Sciences, Edwards Peter A, Glucose/metabolism, Gonzalez Frank J, Hepatocyte Nuclear Factor 4/metabolism, Homeostasis, Humans, Lipoproteins/metabolism, Liver/metabolism, Ma Huiyan, Mice, Models, NEOMED College of Medicine, Receptors, Scavenger Receptors, The Journal of biological chemistry, Willson Timothy M, Yin Liya, Zhang Yanqiao
Glucose and insulin induction of bile acid synthesis: mechanisms and implication in diabetes and obesity.
Tags: *Gene Expression Regulation, 2012, Animals, Bile Acids and Salts/*biosynthesis, Boehme Shannon, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/genetics/*metabolism, Cytoplasmic and Nuclear/genetics/metabolism, Department of Integrative Medical Sciences, Diabetes Mellitus, Dietary Fats/administration & dosage/adverse effects, Enzymologic, Epigenesis, Erickson Sandra K, Experimental/genetics/*metabolism, Fasting/metabolism, Francl Jessica M, Genetic/genetics, Glucose/*metabolism/pharmacology, Insulin/*metabolism, Klaassen Curtis D, Li Tiangang, Mice, NEOMED College of Medicine, Obesity/etiology/genetics/*metabolism, Ochoa Adrian, Postprandial Period/genetics, Receptors, Sweetening Agents/pharmacology, The Journal of biological chemistry, Transgenic, Zhang Youcai
Farnesoid X receptor induces Takeda G-protein receptor 5 cross-talk to regulate bile acid synthesis and hepatic metabolism.
Tags: *bile acid, *bile acid metabolism, *FXR, *Gene Expression Regulation, *GLP-1, *Lipid Metabolism, *liver metabolism, *Non-alcoholic Fatty Liver Disease, *Obesity, *TGR5, *type 2 diabetes, 2017, Animals, Bile Acids and Salts/*biosynthesis/genetics, Boehme Shannon, Chiang John Y L, Cytoplasmic and Nuclear/genetics/*metabolism, Department of Integrative Medical Sciences, Dietary Fats, G-Protein-Coupled/genetics/*metabolism, Glucagon-Like Peptide 1/genetics/metabolism, Glucose/metabolism, Gonzalez Frank, Knockout, Krausz Kristopher W, Lipid Metabolism, Liu Hailiang, Liver/*metabolism, Mice, NEOMED College of Medicine, Obesity/genetics/*metabolism/pathology, Pathak Preeti, Receptors, The Journal of biological chemistry, Xie Cen
Effect of aging on the substance P receptor, NK-1, in the spinal cord of rats with peripheral nerve injury.
Tags: *Peripheral Nerve Injuries, 2001, Aging/*physiology, Animals, Computer-Assisted, Crisp T, Cruce W L, Hot Temperature, Image Processing, Immunohistochemistry, Inbred BN, Inbred F344, Lovell J A, Neurokinin-1/*metabolism, Rats, Receptors, Somatosensory & motor research, Spinal Cord/*metabolism, Stuesse S L, Thermosensing/physiology, Touch/physiology
Bile acids as metabolic regulators.
Tags: 2015, Bile Acids and Salts/*metabolism, Biological Transport, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/metabolism, Current opinion in gastroenterology, Cytoplasmic and Nuclear/metabolism, Department of Integrative Medical Sciences, Diabetes Mellitus, Energy Metabolism, Homeostasis, Humans, Inflammation/*metabolism, Intestine, Li Tiangang, Liver/*metabolism/pathology, NEOMED College of Medicine, Obesity/*metabolism, Receptors, Signal Transduction, Small/*metabolism/pathology, Type 2/*metabolism
Two GABAA responses with distinct kinetics in a sound localization circuit.
Tags: *Sound, 2012, Animals, Chick Embryo, Chickens, Department of Anatomy & Neurobiology, Female, GABA-A/*physiology, gamma-Aminobutyric Acid/metabolism, Lu Yong, Male, NEOMED College of Medicine, Neurons/*metabolism, Pitch Discrimination, Receptors, Sound Localization/*physiology, Synapses/physiology, Tang Zheng-Quan, The Journal of physiology
Rifampicin induction of CYP3A4 requires pregnane X receptor cross talk with hepatocyte nuclear factor 4alpha and coactivators, and suppression of small heterodimer partner gene expression.
Tags: 2006, Antibiotics, Antitubercular/*pharmacology, Blotting, Cell Line, Chiang John Y L, Chromatin/metabolism, Cytochrome P-450 CYP3A, Cytochrome P-450 Enzyme System/*biosynthesis, Cytoplasmic and Nuclear/*biosynthesis/*drug effects/genetics, Department of Integrative Medical Sciences, Drug metabolism and disposition: the biological fate of chemicals, Electrophoretic Mobility Shift Assay, Enzyme Induction/drug effects, Glutathione Transferase/metabolism, Hepatocyte Nuclear Factor 4/genetics/*metabolism, Hepatocytes/drug effects/metabolism, Humans, Immunoprecipitation, Li Tiangang, Messenger/biosynthesis, NEOMED College of Medicine, Plasmids/genetics, Pregnane X Receptor, Receptor Cross-Talk/drug effects, Receptors, Reverse Transcriptase Polymerase Chain Reaction, Rifampin/*pharmacology, RNA, Steroid/*drug effects/genetics, Transfection, Tumor, Western
Mechanism of vitamin D receptor inhibition of cholesterol 7alpha-hydroxylase gene transcription in human hepatocytes.
Tags: 2009, Base Sequence, Calcitriol/drug effects/genetics/*physiology, Cell Line, Cells, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*genetics, Cultured, Department of Integrative Medical Sciences, DNA Primers, Drug metabolism and disposition: the biological fate of chemicals, Electrophoretic Mobility Shift Assay, Gene Knockdown Techniques, Genetic/*physiology, Han Shuxin, Hepatocytes/*drug effects/enzymology, Humans, Immunoprecipitation, Lithocholic Acid/pharmacology, Messenger/genetics, NEOMED College of Medicine, Polymerase Chain Reaction, Receptors, RNA, Small Interfering, Transcription, Tumor, Two-Hybrid System Techniques
Farnesoid X Receptor Agonist Represses Cytochrome P450 2D6 Expression by Upregulating Small Heterodimer Partner.
Tags: 2015, Animals, Cytochrome P-450 CYP2D6/*biosynthesis, Cytochrome P-450 Enzyme Inhibitors/*pharmacology, Cytoplasmic and Nuclear/*agonists, Department of Integrative Medical Sciences, Drug metabolism and disposition: the biological fate of chemicals, Enzymologic/drug effects, Gene Expression Regulation, Genetic/drug effects/genetics, HEK293 Cells, Hepatocytes/drug effects/enzymology/metabolism, Humans, Isoxazoles/*pharmacology, Jeong Hyunyoung, Knockout, Lee Yoon-Kwang, Mice, NEOMED College of Medicine, Pan Xian, Receptors, Transcription, Transgenic
A novel mechanism of neurokinin-1 receptor resensitization.
Tags: 2002, Animals, Bennett V J, Cell Membrane/drug effects/metabolism, CHO Cells, Concanavalin A/pharmacology, Cricetinae, Monensin/pharmacology, Neurokinin-1/*agonists/*metabolism, Perrine S A, Phosphorylation/drug effects, Rats, Receptors, Simmons M A, The Journal of pharmacology and experimental therapeutics
Activation of metabotropic glutamate receptor 1 dimers requires glutamate binding in both subunits.
Tags: 2005, Blotting, Calcium Channels/drug effects/metabolism, Department of Integrative Medical Sciences, DNA/biosynthesis/genetics, Dose-Response Relationship, Drug, Fluorescent Antibody Technique, Genes, Glutamic Acid/*metabolism, Humans, Kammermeier Paul J, Membrane Potentials/drug effects, Metabotropic Glutamate/genetics/*metabolism, myc/genetics, NEOMED College of Medicine, Patch-Clamp Techniques, Plasmids/genetics, Receptors, Signal Transduction/drug effects, Superior Cervical Ganglion/cytology/drug effects/metabolism, Sympathetic Nervous System/cytology/drug effects/metabolism, The Journal of pharmacology and experimental therapeutics, Western, Yun June
Neurokinin-1 receptor resensitization precedes receptor recycling.
Tags: 2005, Adenosine Triphosphate/pharmacology, Animals, Bennett V J, Binding, Calcium/metabolism, CHO Cells, Competitive, Cricetinae, Guanylyl Imidodiphosphate/pharmacology, Neurokinin-1/*metabolism, Perrine S A, Phosphorylation, Rats, Receptors, Simmons M A, Substance P/metabolism, The Journal of pharmacology and experimental therapeutics
Functional selectivity of NK1 receptor signaling: peptide agonists can preferentially produce receptor activation or desensitization.
Tags: 2006, Animals, CHO Cells, Cricetinae, Dose-Response Relationship, Drug, Humans, Neurokinin-1/agonists/drug effects/*physiology, Rana catesbeiana, Rats, Receptors, Signal Transduction/*physiology, Simmons Mark A, Substance P/metabolism/pharmacology, Tachykinins/metabolism/pharmacology, The Journal of pharmacology and experimental therapeutics
A noninflammatory interleukin-1beta fragment stimulates fetal lung fluid absorption in guinea pigs.
Tags: 2007, Absorption, Adrenergic, Adrenocorticotropic Hormone/blood, Animals, Beard LaMonta L, beta/analysis, Body Fluids/drug effects/metabolism, Department of Integrative Medical Sciences, Epithelial Sodium Channels/genetics, Female, Fetus/drug effects, Folkesson Hans G, Guinea Pigs, Hydrocortisone/biosynthesis, Interleukin-1beta/*pharmacology, Li Tianbo, Lung/*drug effects/metabolism, Messenger/analysis, NEOMED College of Medicine, Oxytocin/pharmacology, Peptide Fragments/*pharmacology, Pregnancy, Receptors, RNA, The Journal of pharmacology and experimental therapeutics, Varadarajulu Shilpa, Yun June
Functional selectivity, ligand-directed trafficking, conformation-specific agonism: what's in a name?
Specificity of metabotropic glutamate receptor 2 coupling to G proteins.
Tags: 2003, Amino Acid, Amino Acid Sequence, Animals, Calcium/metabolism, Davis Margaret I, Electrophysiology, Gi-Go/metabolism, GTP-Binding Protein alpha Subunits, GTP-Binding Proteins/*metabolism, Ikeda Stephen R, Kammermeier Paul J, Metabotropic Glutamate/*metabolism, Molecular pharmacology, Molecular Sequence Data, Neurons/*drug effects/metabolism, Pertussis Toxin/*pharmacology, Rats, Receptors, Sequence Homology, Superior Cervical Ganglion/cytology, Wistar
Bile acid signaling in metabolic disease and drug therapy.
Tags: 2014, Animals, Bile Acids and Salts/biosynthesis/*metabolism/therapeutic use, Biological, Chiang John Y L, Circadian Rhythm/physiology, Department of Integrative Medical Sciences, G-Protein-Coupled/metabolism, Glucose/metabolism, Humans, Li Tiangang, Lipid Metabolism/physiology, Liver/metabolism, Metabolic Diseases/*drug therapy/*metabolism, Microbiota/physiology, MicroRNAs/metabolism, Models, NEOMED College of Medicine, Pharmacological reviews, Receptors, Signal Transduction/physiology
Estrogen-related receptor gamma controls hepatic CB1 receptor-mediated CYP2E1 expression and oxidative liver injury by alcohol.
Tags: 2013, Alcohol-Induced Injury, Alcoholic Liver Disease, Alcoholic/genetics/*metabolism/prevention & control, Animals, Cannabinoid, CB1/*physiology, Chiang John Y L, Choi Hueng-Sik, Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 CYP2E1/genetics/*metabolism, Department of Integrative Medical Sciences, Enzyme Inhibitors/pharmacology/therapeutic use, Enzymologic/drug effects/physiology, Estrogen/deficiency/genetics/*physiology, Ethanol/pharmacology, Gene Expression Profiling/methods, Gene Expression Regulation, Gene Regulation, Genetic/physiology, Gut, Inbred C57BL, Jang Hyun-Hee, Jeong Won-Il, Kim Don-Kyu, Kim Jung Ran, Kim Yong-Hoon, Knockout, Koh Minseob, Koo Seung-Hoi, Lee Chul-Ho, Liver, Liver Diseases, Liver Metabolism, Liver/metabolism, Male, Mice, NEOMED College of Medicine, Oxidation-Reduction, Oxidative Stress/physiology, Park Jinyoung, Park Seung Bum, Park Tae-Sik, Receptor, Receptors, Signal Transduction/drug effects/physiology, Tamoxifen/analogs & derivatives/pharmacology/therapeutic use, Transcription, Yun Chul-Ho
Mechanism of rifampicin and pregnane X receptor inhibition of human cholesterol 7 alpha-hydroxylase gene transcription.
Tags: 2005, American journal of physiology. Gastrointestinal and liver physiology, Bile Acids and Salts/pharmacology, Chiang John Y L, Cholestasis/*physiopathology, Cholesterol 7-alpha-Hydroxylase/*biosynthesis/pharmacology, Cultured, Cytoplasmic and Nuclear/*physiology, Department of Integrative Medical Sciences, DNA-Binding Proteins/pharmacology, Enzyme Inhibitors/*pharmacology, Genetic, Glucocorticoid, Hepatoblastoma/pathology, Hepatocyte Nuclear Factor 4, Humans, Li Tiangang, Liver Neoplasms/pathology, Messenger/analysis/biosynthesis, NEOMED College of Medicine, Phosphoproteins/pharmacology, Pregnane X Receptor, Receptors, Rifampin/*pharmacology, RNA, Steroid/*physiology, Transcription, Transcription Factors/pharmacology, Tumor Cells, Up-Regulation
Enhanced ethanol catabolism in orphan nuclear receptor SHP-null mice.
Tags: *acetaldehyde dehydrogenase, *alcoholic fatty liver disease, *Inflammation, *small heterodimer partner, 2016, Acetates/blood, Alcoholic/genetics/*metabolism, Aldehyde Dehydrogenase, American journal of physiology. Gastrointestinal and liver physiology, Animals, Cytoplasmic and Nuclear/deficiency/*genetics/metabolism, Department of Integrative Medical Sciences, Ethanol/blood/*metabolism/toxicity, Inbred C57BL, Lee Mikang, Lee Yoon-Kwang, Lipid Peroxidation, Liver Diseases, Liver/drug effects/metabolism, Male, Mice, Mifflin Ryan, Mitochondrial/genetics/metabolism, NEOMED College of Medicine, Park Jung Eun, PPAR gamma/genetics/metabolism, Receptors
Bile acid regulation of hepatic physiology: III. Bile acids and nuclear receptors.
Tags: 2003, American journal of physiology. Gastrointestinal and liver physiology, Animals, Bile Acids and Salts/biosynthesis/genetics/*physiology, Bile/*physiology, Cardiovascular Diseases/genetics/physiopathology, Chiang John Y L, Cholesterol/physiology, Cytoplasmic and Nuclear/*physiology, Department of Integrative Medical Sciences, Feedback/physiology, Gene Expression Regulation/physiology, Humans, Liver Diseases/genetics/physiopathology, Liver/*physiology, NEOMED College of Medicine, Receptors
Early upregulation of myocardial CXCR4 expression is critical for dimethyloxalylglycine-induced cardiac improvement in acute myocardial infarction.
Tags: 2016, alpha Subunit/metabolism, American journal of physiology. Heart and circulatory physiology, Amino Acids, Animal, Animals, Apoptosis/drug effects, Cardiotonic Agents/*pharmacology, Cell Hypoxia, Cell Line, Chilian William M, CXCR4/deficiency/genetics/*metabolism, Department of Integrative Medical Sciences, Dicarboxylic/*pharmacology, Disease Models, Dong Feng, Enzyme Inhibitors/pharmacology, Forudi Farhad, hypoxia, Hypoxia-Inducible Factor 1, Hypoxia-Inducible Factor-Proline Dioxygenases/antagonists & inhibitors/metabolism, Inbred C57BL, Kiedrowski Matthew, Knockout, Left/*drug effects, Mayorga Mari, Mice, myocardial infarction, Myocardial Infarction/*drug therapy/genetics/metabolism/pathology/physiopathology, Myocardium/*metabolism/pathology, NEOMED College of Medicine, Penn Marc S, Rats, Receptors, Recovery of Function, Shamhart Patricia, Signal Transduction/drug effects, stem cells, Stem Cells/drug effects/metabolism, Stroke Volume/drug effects, Time Factors, Up-Regulation, Ventricular Function, Weber Kristal
Impaired alveolar liquid clearance after 48-h isoproterenol infusion spontaneously recovers by 96 h of continuous infusion.
Tags: *Pulmonary Alveoli/drug effects/metabolism, 2006, Adrenergic, Adrenergic beta-Antagonists/pharmacology, American journal of physiology. Lung cellular and molecular physiology, Animals, beta-2/metabolism, Bronchodilator Agents/administration & dosage/*pharmacology, Folkesson Hans G, Hodnichak Cheryl M, Isoproterenol/administration & dosage/*pharmacology, Lung/drug effects/metabolism, Male, Maron Michael B, Propranolol/pharmacology, Rats, Receptors, Sprague-Dawley, Stader Sonya M, Terbutaline/pharmacology, Time Factors
Postreceptor defects in alveolar epithelial beta-adrenergic signaling after prolonged isoproterenol infusion.
Tags: 2003, 8-Bromo Cyclic Adenosine Monophosphate/pharmacology, Adenylyl Cyclases/metabolism, Adrenergic, Adrenergic beta-Agonists/*pharmacology, American journal of physiology. Lung cellular and molecular physiology, Animals, beta/*metabolism, Colforsin/pharmacology, Cyclic AMP-Dependent Protein Kinase Type II, Cyclic AMP-Dependent Protein Kinases/metabolism, Cyclic AMP/metabolism, Extravascular Lung Water/metabolism, Folkesson Hans G, Hodnichak Cheryl M, Isoproterenol/*pharmacology, Male, Maron Michael B, Mavrich Kate E, Morgan Eric E, Pulmonary Alveoli/*drug effects/*metabolism, Pulmonary Edema/metabolism, Rats, Receptors, Respiratory Mucosa/drug effects/metabolism, Signal Transduction/drug effects, Sprague-Dawley, Stader Sonya M
Prolonged isoproterenol infusion impairs the ability of beta(2)-agonists to increase alveolar liquid clearance.
Tags: 2002, Adrenergic, Adrenergic beta-Agonists/*pharmacology, American journal of physiology. Lung cellular and molecular physiology, Animals, beta/metabolism, Boja John W, Down-Regulation/drug effects, Drug Interactions, Epithelial Cells/metabolism, Extravascular Lung Water/*metabolism, Folkesson Hans G, Hodnichak Cheryl M, Isoproterenol/*pharmacology, Maender Kay C, Male, Maron Michael B, Morgan Eric E, Pulmonary Alveoli/cytology/*metabolism, Pulmonary Circulation/physiology, Pulmonary Edema/metabolism, Rats, Receptors, Respiratory Mucosa/cytology/*metabolism, Sprague-Dawley, Stader Sonya M, Terbutaline/pharmacology
Beta-adrenoceptor stimulation of alveolar fluid clearance is increased in rats with heart failure.
Tags: 2009, Adrenergic, American journal of physiology. Lung cellular and molecular physiology, Animals, beta/*metabolism, Body Fluids/*metabolism, Department of Integrative Medical Sciences, Epithelial Cells/drug effects/metabolism/pathology, Folkesson Hans G, Gene Expression Regulation/drug effects, Heart Failure/blood/diagnostic imaging/*metabolism/*pathology, Hormones/blood, Horne Walter I, Hyperplasia, Ion Channels/genetics/metabolism, Koshy Shyny, Li Tianbo, Luther Daniel J, Male, Maron Michael B, Messenger/genetics/metabolism, Meszaros J Gary, Myocardial Infarction/blood/diagnostic imaging/pathology, NEOMED College of Medicine, Ohanyan Vahagn, Pilati Charles F, Pulmonary Alveoli/drug effects/*pathology, Rats, Receptors, RNA, Sprague-Dawley, Terbutaline/pharmacology, Ultrasonography, Walro Jon M
Reduced vascular responsiveness after a single bout of dynamic exercise in the conscious rabbit.
Tags: 1992, Adenosine/pharmacology, Adrenergic/physiology, Animals, Blood Vessels/*physiology, DiCarlo S E, Dose-Response Relationship, Drug, Hindlimb/physiology, Howard M G, In Vitro Techniques, Isoproterenol/pharmacology, Journal of applied physiology (Bethesda, Md. : 1985), Phenylephrine/pharmacology, Physical Exertion/*physiology, Pressoreceptors/physiology, Purinergic/physiology, Rabbits, Receptors, Reflex/physiology, Regional Blood Flow/physiology
Effect of epinephrine on alveolar liquid clearance in the rat.
Tags: 1999, Adrenergic, Adrenergic beta-Agonists/*pharmacology, Amiloride/pharmacology, Animals, beta/metabolism, Bronchoalveolar Lavage Fluid/chemistry, Charron P D, Epinephrine/blood/*pharmacology, Fawley J P, Journal of applied physiology (Bethesda, Md. : 1985), Male, Maron M B, Norepinephrine/blood, Propranolol/pharmacology, Pulmonary Alveoli/*drug effects, Rats, Receptors, Serum Albumin/metabolism, Sprague-Dawley, Time Factors
Glycinergic inhibition creates a form of auditory spectral integration in nuclei of the lateral lemniscus.
Tags: 2009, Acoustic Stimulation, Action Potentials/drug effects, Animals, Auditory Perception/drug effects/*physiology, Bicuculline/pharmacology, Brain Stem/drug effects/*physiology, Chiroptera, College of Anatomy & Neurobiology, Department of Anatomy & Neurobiology, GABA Antagonists/pharmacology, GABA-A Receptor Antagonists, GABA-A/metabolism, gamma-Aminobutyric Acid/metabolism, Glycine Agents/pharmacology, Glycine/*physiology, Glycine/antagonists & inhibitors/metabolism, Journal of neurophysiology, Microelectrodes, Nataraj Kiran, NEOMED College of Medicine, Neural Inhibition/drug effects/*physiology, Neurons/drug effects/*physiology, Peterson Diana Coomes, Receptors, Strychnine/pharmacology, Wenstrup Jeffrey
Endogenous mGluR activity suppresses GABAergic transmission in avian cochlear nucleus magnocellularis neurons.
Tags: 2-Amino-5-phosphonovalerate/pharmacology, 2007, Amino Acids/pharmacology, Animals, Chickens/*physiology, Cochlear Nucleus/*cytology/*physiology, Department of Anatomy & Neurobiology, Electric Stimulation, Excitatory Amino Acid Antagonists/pharmacology, Excitatory Postsynaptic Potentials/physiology, GABA-B Receptor Agonists, GABA-B Receptor Antagonists, GABA-B/physiology, gamma-Aminobutyric Acid/*physiology, Glycine/analogs & derivatives/pharmacology, In Vitro Techniques, Journal of neurophysiology, Kinetics, Lu Yong, Membrane Potentials/drug effects, Metabotropic Glutamate/agonists/antagonists & inhibitors/*metabolism/physiology, Models, NEOMED College of Medicine, Neurological, Neurons/*physiology, Patch-Clamp Techniques, Receptors, Resorcinols/pharmacology, Synapses/physiology, Synaptic Transmission/*physiology, Xanthenes/pharmacology
Roles of inhibition in complex auditory responses in the inferior colliculus: inhibited combination-sensitive neurons.
Tags: 2006, Acoustic Stimulation, Action Potentials/drug effects/physiology, Afferent/drug effects/*physiology, Animals, Auditory, Auditory Pathways/drug effects/*physiology, Bicuculline/pharmacology, Brain Stem/drug effects/*physiology, Chiroptera, College of Anatomy & Neurobiology, Department of Anatomy & Neurobiology, Electrophysiology, Evoked Potentials, GABA-A Receptor Antagonists, GABA-A/physiology, Glycine/antagonists & inhibitors/physiology, Inferior Colliculi/*physiology, Journal of neurophysiology, Nataraj Kiran, NEOMED College of Medicine, Neural Inhibition/drug effects/*physiology, Neurons, Receptors, Strychnine/pharmacology, Wenstrup Jeffrey J
Hyperpolarizing and depolarizing GABAA receptor-mediated dendritic inhibition in area CA1 of the rat hippocampus.
Tags: 1991, 2-Amino-5-phosphonovalerate/pharmacology, Animals, Bicuculline/analogs & derivatives/pharmacology, Borroni A M, Chlorides/pharmacology, Dendrites/drug effects/*physiology, Evoked Potentials/drug effects, GABA-A Receptor Antagonists, GABA-A/drug effects/*physiology, Grover L M, Hippocampus/*physiology, In Vitro Techniques, Journal of neurophysiology, Kinetics, Lambert N A, Mathematics, Membrane Potentials/drug effects, Models, Neurological, Neurons/drug effects/*physiology, Organophosphorus Compounds/pharmacology, Pyramidal Tracts/drug effects/*physiology, Quinoxalines/pharmacology, Rats, Receptors, Synapses/drug effects/physiology, Teyler T J
Role of HCO3- ions in depolarizing GABAA receptor-mediated responses in pyramidal cells of rat hippocampus.
Tags: 1993, Afferent Pathways/physiology, Animals, Bicarbonates/*metabolism, Culture Techniques, Electric Stimulation, GABA-A/*physiology, gamma-Aminobutyric Acid/physiology, Grover L M, Hippocampus/*physiology, Interneurons/physiology, Journal of neurophysiology, Lambert N A, Membrane Potentials/physiology, Neurons/physiology, Rats, Receptors, Schwartzkroin P A, Synapses/physiology, Synaptic Transmission/*physiology, Teyler T J
VDCCs and NMDARs underlie two forms of LTP in CA1 hippocampus in vivo.
Tags: 1999, Animals, Calcium Channel Blockers/*pharmacology, Dizocilpine Maleate/pharmacology, Excitatory Amino Acid Antagonists/*pharmacology, Excitatory Postsynaptic Potentials/drug effects, Hippocampus/*drug effects, Journal of neurophysiology, Long-Evans, Long-Term Potentiation/*drug effects, Male, Membrane Potentials/physiology, Morgan S L, N-Methyl-D-Aspartate/*antagonists & inhibitors, Rats, Receptors, Teyler T J, Verapamil/pharmacology
Electrical stimuli patterned after the theta-rhythm induce multiple forms of LTP.
Tags: *Theta Rhythm, 2-Amino-5-phosphonovalerate/pharmacology, 2001, Animals, Calcium Channel Blockers/pharmacology, Calcium Channels/physiology, Excitatory Amino Acid Agonists/pharmacology, Excitatory Amino Acid Antagonists/pharmacology, Excitatory Postsynaptic Potentials/drug effects/physiology, Journal of neurophysiology, Long-Evans, Long-Term Potentiation/drug effects/*physiology, Male, Morgan S L, N-Methyl-D-Aspartate/physiology, N-Methylaspartate/pharmacology, Neuronal Plasticity/drug effects/*physiology, Nifedipine/pharmacology, Organ Culture Techniques, Rats, Receptors, Teyler T J
Role of the adjacent stroma cells in prostate cancer development and progression: synergy between TGF-beta and IGF signaling.
Tags: 2014, Androgens/metabolism, Animals, BioMed research international, Disease Progression, Epithelial Cells/cytology, Estrogen/metabolism, Estrogens/metabolism, Humans, Jia Zhenyu, Lee Chung, Male, McClelland Michael, Mercola Dan, Mice, Prostate/metabolism, Prostatic Neoplasms/*metabolism, Rahmatpanah Farah, Receptors, Signal Transduction, Somatomedins/*metabolism, Stromal Cells/*cytology, Transforming Growth Factor beta/*metabolism, Zhang Qiang, Zi Xiaolin
Intestinal Farnesoid X Receptor and Takeda G Protein Couple Receptor 5 Signaling in Metabolic Regulation.
Tags: *Signal Transduction, 2017, Animals, Bile Acids and Salts/biosynthesis/metabolism, Boehme Shannon, Chiang John Y L, Cytoplasmic and Nuclear/*metabolism, Department of Integrative Medical Sciences, Digestive diseases (Basel, Switzerland), Donepudi Ajay, Ferrell Jessica, G-Protein-Coupled/*metabolism, Humans, Intestinal Mucosa/*metabolism, Liu Hailiang, Liver/metabolism, NEOMED College of Medicine, Pathak Preeti, Receptors
Farnesoid X Receptor Activation by Obeticholic Acid Elevates Liver Low-Density Lipoprotein Receptor Expression by mRNA Stabilization and Reduces Plasma Low-Density Lipoprotein Cholesterol in Mice.
Myocardial CXCR4 expression is required for mesenchymal stem cell mediated repair following acute myocardial infarction.
Tags: 2012, Agarwal Udit, Animals, Apoptosis/physiology, Cardiac/cytology/physiology, Cell Movement/physiology, Chemokine CXCL12/*metabolism, Circulation, Coronary Circulation/physiology, CXCR4/*genetics/metabolism, Department of Integrative Medical Sciences, Dong Feng, Finan Amanda, Gene Expression/physiology, Green Fluorescent Proteins/genetics, Harvey James, Inbred C57BL, Knockout, Mesenchymal Stem Cell Transplantation/*methods, Mesenchymal Stem Cells/*metabolism, Mice, Myocardial Infarction/genetics/pathology/*therapy, Myocardium/cytology, Myocytes, NEOMED College of Medicine, Paracrine Communication/physiology, Penn Marc S, Receptors, Ventricular Remodeling/physiology, Weber Kristal