Browse Items (90 total)
- Tags: RNA
Inhibition of cartilage degradation and suppression of PGE2 and MMPs expression by pomegranate fruit extract in a model of posttraumatic osteoarthritis.
Tags: *Phytotherapy, *Punicaceae, 2017, ACLT, Akhtar Nahid, Animal, Animals, Anterior Cruciate Ligament/drug effects/metabolism/pathology, Apoptosis, Ashruf Omer S, Cartilage/cytology/*drug effects/metabolism/pathology, Chondrocytes/drug effects/metabolism/pathology, Collagen Type II/genetics/metabolism, Department of Anatomy & Neurobiology, Dinoprostone/*metabolism, Disease Models, Disease Progression, Female, Fruit, Haqqi Tariq M, Interleukins/metabolism, Joints/cytology/*drug effects/metabolism/pathology, Khan Nazir M, Male, Messenger/metabolism, Metalloproteases/genetics/*metabolism, Mitogen-Activated Protein Kinases/metabolism, MMPs, NEOMED College of Medicine, NF-kappa B/metabolism, Nutrition (Burbank, Los Angeles County, Calif.), Osteoarthritis, Osteoarthritis/*drug therapy/etiology/metabolism/pathology, PGE(2), Plant Extracts/pharmacology/therapeutic use, Pomegranate, Rabbit, Rabbits, RNA, Synovial Fluid/metabolism
Interleukin-1beta induced Stress Granules Sequester COX-2 mRNA and Regulates its Stability and Translation in Human OA Chondrocytes.
Tags: *Protein Biosynthesis, 2016, Ansari Mohammad Y, Cells, Chondrocytes/drug effects/metabolism/pathology, Cultured, Cyclooxygenase 2/*genetics, Department of Anatomy & Neurobiology, Dinoprostone/genetics, Fluorescence, Gene Expression Regulation, Haqqi Tariq M, Humans, Immunoprecipitation, In Situ Hybridization, Interleukin-1beta/administration & dosage/*genetics, Messenger/genetics, NEOMED College of Medicine, Nitric Oxide/metabolism, Osteoarthritis/drug therapy/*genetics/pathology, RNA, Scientific reports
Intestinal Flora Modification of Arthritis Pattern in Spondyloarthropathy.
Tags: *Bacteria/classification/genetics/isolation & purification, *Diarrhea/complications/microbiology, *Gastrointestinal Microbiome, *Spondylarthropathies/diagnosis/etiology/physiopathology, 16S/analysis, 2015, Animal, Animals, Disease Models, Gastrointestinal Tract/*microbiology, Gorilla gorilla, Humans, Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, Pan troglodytes, Protective Factors, Ribosomal, RNA, Rothschild Bruce M
Intrajoint comparisons of gene expression patterns in human osteoarthritis suggest a change in chondrocyte phenotype.
Tags: *Gene Expression Profiling, 2005, 80 and over, Aged, Articular/*metabolism, Cartilage, Chondrocytes/*metabolism, Collagen Type II/genetics, Department of Anatomy & Neurobiology, Glycosaminoglycans/analysis, High Mobility Group Proteins/genetics, Horton Walter E Jr, Humans, Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Laverty David, Matrix Metalloproteinase 3/genetics, Matrix Metalloproteinase 9/genetics, McBurney Denise, Messenger/analysis, NEOMED College of Medicine, Osteoarthritis/*metabolism, Phenotype, Proto-Oncogene Proteins c-bcl-2/genetics, RNA, SOX9 Transcription Factor, Transcription Factors/genetics, Weiner Scott, Yagi Rieko
Involvement of {alpha}ENaC and Nedd4-2 in the conversion from lung fluid secretion to fluid absorption at birth in the rat as assayed by RNA interference analysis.
Tags: *RNA Interference, 2007, Absorption, American journal of physiology. Lung cellular and molecular physiology, Animals, Body Fluids/*metabolism, Death, Endosomal Sorting Complexes Required for Transport, Epithelial Sodium Channels/genetics/*physiology, Extravascular Lung Water/metabolism, Folkesson Hans G, Gene Silencing, Koshy Shyny, Li Tianbo, Lung/*metabolism, Nedd4 Ubiquitin Protein Ligases, Newborn/*metabolism, Rats, RNA, Small Interfering/metabolism, Sodium-Potassium-Exchanging ATPase/metabolism, Sprague-Dawley, Tissue Distribution, Ubiquitin-Protein Ligases/genetics/metabolism/*physiology
Isolation and characterization of cDNA clones for human, bovine and rabbit liver cytochrome b5 mRNA's.
Tags: 1989, Amino Acid Sequence, Animals, Base Sequence, Cattle, Chickens, Cloning, Cristiano R J, Cytochromes b5/blood/*genetics, Dariush N, DNA/*isolation & purification, Erythrocytes/enzymology, Humans, Liver/*enzymology, Messenger/*genetics, Molecular, Molecular Sequence Data, Nucleic Acid, Progress in clinical and biological research, Rabbits, RNA, Sequence Homology, Steggles A W, Yoo M
Mechanism of rifampicin and pregnane X receptor inhibition of human cholesterol 7 alpha-hydroxylase gene transcription.
Tags: 2005, American journal of physiology. Gastrointestinal and liver physiology, Bile Acids and Salts/pharmacology, Chiang John Y L, Cholestasis/*physiopathology, Cholesterol 7-alpha-Hydroxylase/*biosynthesis/pharmacology, Cultured, Cytoplasmic and Nuclear/*physiology, Department of Integrative Medical Sciences, DNA-Binding Proteins/pharmacology, Enzyme Inhibitors/*pharmacology, Genetic, Glucocorticoid, Hepatoblastoma/pathology, Hepatocyte Nuclear Factor 4, Humans, Li Tiangang, Liver Neoplasms/pathology, Messenger/analysis/biosynthesis, NEOMED College of Medicine, Phosphoproteins/pharmacology, Pregnane X Receptor, Receptors, Rifampin/*pharmacology, RNA, Steroid/*physiology, Transcription, Transcription Factors/pharmacology, Tumor Cells, Up-Regulation
Mechanism of vitamin D receptor inhibition of cholesterol 7alpha-hydroxylase gene transcription in human hepatocytes.
Tags: 2009, Base Sequence, Calcitriol/drug effects/genetics/*physiology, Cell Line, Cells, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*genetics, Cultured, Department of Integrative Medical Sciences, DNA Primers, Drug metabolism and disposition: the biological fate of chemicals, Electrophoretic Mobility Shift Assay, Gene Knockdown Techniques, Genetic/*physiology, Han Shuxin, Hepatocytes/*drug effects/enzymology, Humans, Immunoprecipitation, Lithocholic Acid/pharmacology, Messenger/genetics, NEOMED College of Medicine, Polymerase Chain Reaction, Receptors, RNA, Small Interfering, Transcription, Tumor, Two-Hybrid System Techniques
MicroRNA-9 promotion of interleukin-6 expression by inhibiting monocyte chemoattractant protein-induced protein 1 expression in interleukin-1beta-stimulated human chondrocytes.
Tags: 2015, Academic Medical Centers, Aged, Arthritis & rheumatology (Hoboken, N.J.), Articular/drug effects/*metabolism, Cartilage, Cells, Chondrocytes – Physiology, Chondrocytes/drug effects/*metabolism, Cultured, Department of Anatomy & Neurobiology, Enzyme-Linked Immunosorbent Assay, Funding Source, Gene Knockdown Techniques, Haqqi Tariq M, Haseeb Abdul, Hip/*genetics/metabolism, Human, Humans, Immunoblotting – Utilization, Immunoprecipitation, Interleukin-1beta/pharmacology, Interleukin-6/*genetics/metabolism, Interleukins – Physiology, Makki Mohammad S, Messenger/drug effects/*metabolism, MicroRNAs/drug effects/*genetics/metabolism, Middle Aged, NEOMED College of Medicine, Ohio, Osteoarthritis, Osteoarthritis – Complications, Osteoarthritis – Physiopathology, Reverse Transcriptase Polymerase Chain Reaction, Ribonucleases/drug effects/*genetics/metabolism, RNA, T-Tests, Transcription Factors/drug effects/*genetics/metabolism
miR-139 modulates MCPIP1/IL-6 expression and induces apoptosis in human OA chondrocytes.
Tags: *Apoptosis, 2015, 3' Untranslated Regions, Aged, Chondrocytes/*metabolism/pathology, Department of Anatomy & Neurobiology, Down-Regulation, Experimental & molecular medicine, Female, Gene Expression Regulation, Haqqi Tariq M, Humans, Interleukin-6/*genetics, Makki Mohammad Shahidul, Male, Messenger/genetics, MicroRNAs/*genetics, Middle Aged, NEOMED College of Medicine, Osteoarthritis/*genetics/pathology, Ribonucleases/*genetics, RNA, Transcription Factors/*genetics, Up-Regulation
MiR-21 enhances melanoma invasiveness via inhibition of tissue inhibitor of metalloproteinases 3 expression: in vivo effects of MiR-21 inhibitor.
Tags: 2015, Carson Mary, Carson William E 3rd, Cell Line, Cell Movement/genetics, Cell Proliferation/genetics, Chan Anthony N, Dao Thao-Vi, Fairchild Ene T, Ganju Akaansha, Gene Expression Regulation, Grignol Valerie P, Humans, Jaime-Ramirez Alena Cristina, Karpa Volodymyr I, Latchana Nicholas, Levine Kala M, Martin del Campo Sara E, Melanoma/*genetics/metabolism/pathology, MicroRNAs/*genetics/metabolism, Neoplasm Invasiveness/*genetics/pathology, Neoplastic, PloS one, RNA, Skin Neoplasms/*genetics/metabolism/pathology, Small Interfering, Tissue Inhibitor of Metalloproteinase-3/*genetics/metabolism, Tumor
Modulation of olfactory bulb tyrosine hydroxylase and catecholamine transporter mRNA by estrogen.
Tags: *Membrane Glycoproteins, *Nerve Tissue Proteins, 2002, Animals, Brain research. Molecular brain research, Delayed-Action Preparations, Dluzen Dean E, Dopamine Plasma Membrane Transport Proteins, Drug Combinations, Estrogen Antagonists/administration & dosage, Estrogens/administration & dosage/*pharmacology, Female, Inbred Strains, Kim Kyungjin, Membrane Transport Proteins/*genetics/metabolism, Messenger/*metabolism, Mice, Molecular Sequence Data, Norepinephrine Plasma Membrane Transport Proteins, Olfactory Bulb/*drug effects/enzymology/*physiology, Ovariectomy, Park June-Hee, Rats, RNA, Symporters/*genetics/metabolism, Tyrosine 3-Monooxygenase/*genetics/metabolism
Modulation of ten-eleven translocation 1 (TET1), Isocitrate Dehydrogenase (IDH) expression, alpha-Ketoglutarate (alpha-KG), and DNA hydroxymethylation levels by interleukin-1beta in primary human chondrocytes.
Tags: *DNA methylation, *Epigenesis, 2014, 5-hmC, 5-Methylcytosine/analogs & derivatives, Chondrocytes, Chondrocytes/chemistry/*metabolism, Cytokine, Cytosine/*analogs & derivatives/analysis/metabolism, Department of Anatomy & Neurobiology, Dioxygenase, DNA Methylation, DNA-Binding Proteins/*biosynthesis/genetics, Epigenetics, Genetic, Haqqi Tariq M, Haseeb Abdul, Humans, IL-1, Interleukin-1beta/pharmacology/*physiology, Isocitrate Dehydrogenase/*biosynthesis/genetics, Ketoglutaric Acids/*metabolism, Makki Mohammad Shahidul, Messenger/biosynthesis/genetics, Mixed Function Oxygenases, NEOMED College of Medicine, Primary Cell Culture, Proto-Oncogene Proteins/*biosynthesis/genetics, RNA, The Journal of biological chemistry, TNF-alpha, Tumor Necrosis Factor-alpha/pharmacology/physiology
Nuclear receptor-mediated repression of human cholesterol 7alpha-hydroxylase gene transcription by bile acids.
Tags: *Hydroxysteroid Dehydrogenases, *Membrane Glycoproteins, 2001, Animals, Bile Acids and Salts/*pharmacology, Caco-2 Cells, Carrier Proteins/genetics/physiology, Cell Line, Chen W, Chiang J Y, CHO Cells, Cholesterol 7-alpha-Hydroxylase/*genetics, Cricetinae, Cultured, Cytoplasmic and Nuclear/genetics/*physiology, Department of Integrative Medical Sciences, DNA-Binding Proteins/drug effects/genetics/physiology, DNA/metabolism, Embryo, Gene Expression/*drug effects, Genetic, Genetic/drug effects, Humans, Journal of lipid research, Kidney, Liver/metabolism, Luciferases/genetics, Mammalian, Messenger/analysis, NEOMED College of Medicine, Owsley E, Promoter Regions, Rats, Receptors, Recombinant Fusion Proteins/metabolism, Retinoic Acid/genetics/physiology, Retinoid X Receptors, Reverse Transcriptase Polymerase Chain Reaction, RNA, Stroup D, Taurocholic Acid/pharmacology, Transcription, Transcription Factors/drug effects/genetics/physiology, Transfection, Tumor Cells, Yang Y
Obesity- and sex-related alterations in growth hormone messenger RNA levels.
Tags: 1989, Ahmad I, Animals, Carrillo A J, DNA Probes, Female, Finkelstein J A, Male, Messenger/metabolism, Molecular and cellular endocrinology, Nucleic Acid Hybridization, Obesity/*genetics/metabolism, Prolactin/genetics, Rats, RNA, Sex Characteristics, Somatomedins/*genetics, Steggles A W, Zucker
Obesity-associated decrease in growth hormone-releasing hormone gene expression: a mechanism for reduced growth hormone mRNA levels in genetically obese Zucker rats.
Tags: *Gene Expression, 1993, Ahmad I, Animals, Blotting, Downs T R, Finkelstein J A, Frohman L A, Growth Hormone-Releasing Hormone/*genetics, Growth Hormone/blood/*genetics/metabolism, Male, Messenger/*metabolism, Neuroendocrinology, Northern, Obesity/*metabolism, Pituitary Gland/metabolism, Rats, RNA, Zucker
On the mechanism of bile acid inhibition of rat sterol 12alpha-hydroxylase gene (CYP8B1) transcription: roles of alpha-fetoprotein transcription factor and hepatocyte nuclear factor 4alpha.
Tags: *DNA-Binding Proteins, 2002, alpha-Fetoproteins/genetics/*physiology, Animals, Base Sequence, Bile Acids and Salts/*pharmacology, Biochimica et biophysica acta, Cattle, Chiang John Y L, Cytochrome P-450 Enzyme System/*genetics, Department of Integrative Medical Sciences, DNA, Eggertsen Gosta, Enzymologic/*drug effects/physiology, Gene Expression Regulation, Genetic, Genetic/*drug effects, Hepatocyte Nuclear Factor 4, Messenger/genetics, NEOMED College of Medicine, Phosphoproteins/genetics/*physiology, Promoter Regions, Rats, RNA, Sprague-Dawley, Steroid 12-alpha-Hydroxylase, Steroid Hydroxylases/*genetics, Transcription, Transcription Factors/genetics/*physiology, Yang Yizeng, Zhang Ming
Osteoactivin Promotes Migration of Oral Squamous Cell Carcinomas.
Tags: *Cell Movement, 2016, Arosarena Oneida A, Barr Eric W, Bryant Evan, Carcinoma, Cell Adhesion, Cell Line, Cell Proliferation, Cell Survival, Dela Cadena Raul A, Denny Michael F, Department of Anatomy & Neurobiology, Enzyme Activation, Gene Expression Regulation, Head and Neck Neoplasms/genetics/*metabolism/pathology, Humans, Integrin beta1/metabolism, Journal of cellular physiology, Membrane Glycoproteins/genetics/*metabolism, Messenger/metabolism, Mitogen-Activated Protein Kinases/metabolism, Mouth Neoplasms/genetics/*metabolism/pathology, NEOMED College of Medicine, Neoplasm Invasiveness, Neoplastic, Protein Binding, RNA, RNA Interference, Safadi Fayez F, Signal Transduction, Squamous Cell Carcinoma of Head and Neck, Squamous Cell/genetics/*metabolism/pathology, Thorpe Ryan, Time Factors, Transfection, Tumor
Osteoactivin regulates head and neck squamous cell carcinoma invasion by modulating matrix metalloproteases.
Tags: *Cell Movement, 2018, Arosarena Oneida A, Barr Eric W, Carcinoma, Cell Line, cell lines, Department of Anatomy & Neurobiology, Enzymologic, Extracellular Matrix, Gene Expression Regulation, Head and Neck Neoplasms/*enzymology/genetics/pathology, Human, Humans, Journal of cellular physiology, matrix metalloproteinases, Membrane Glycoproteins/genetics/*metabolism, Messenger/genetics/metabolism, NEOMED College of Medicine, neoplasm invasion, Neoplasm Invasiveness, Neoplastic, RNA, RNA Interference, Safadi Fayez F, Secreted/genetics/*metabolism, Signal Transduction, Squamous Cell Carcinoma of Head and Neck, Squamous Cell/*enzymology/genetics/pathology, Tarr Joseph T, Thorpe Ryan, Transfection, Tumor, Yankey Hilary
Para-chlorophenylalanine treatment inhibits the expression of vasoactive intestinal peptide messenger RNA in rat anterior pituitary.
Tags: 1993, alpha-Methyltyrosine, Animals, Anterior/*drug effects/metabolism, Brain research. Molecular brain research, Carrillo A J, Chemical, Depression, Dluzen D E, Dopamine/metabolism, Fenclonine/*pharmacology, Gene Expression Regulation/drug effects, Male, Messenger/*biosynthesis, Methyltyrosines/pharmacology, Pituitary Gland, Prolactin/metabolism, Rats, RNA, Serotonin/metabolism, Signs S A, Sprague-Dawley, Tryptophan Hydroxylase/antagonists & inhibitors, Vasoactive Intestinal Peptide/*biosynthesis/genetics
PXR induces CYP27A1 and regulates cholesterol metabolism in the intestine.
Tags: *Lipid Metabolism, 2007, ATP Binding Cassette Transporter, ATP Binding Cassette Transporter 1, ATP-Binding Cassette Transporters/genetics, Base Sequence, Cell Line, Chen Wenling, Chiang John Y L, Cholestanetriol 26-Monooxygenase/*metabolism, Cholesterol, Cholesterol/*metabolism, Department of Integrative Medical Sciences, Fluorinated, Genes, Genetic/drug effects, Genetic/genetics, HDL/metabolism, Hepatocytes/drug effects/enzymology/metabolism, Humans, Hydrocarbons, Hydroxycholesterols/metabolism/pharmacology, Intestinal Mucosa/metabolism, Intestines/cytology/drug effects/enzymology, Journal of lipid research, Li Tiangang, Member 1, Messenger/genetics/metabolism, Molecular Sequence Data, NEOMED College of Medicine, Pregnane X Receptor, Promoter Regions, Receptors, Reporter, Response Elements/genetics, Rifampin/pharmacology, RNA, Steroid/*metabolism, Subfamily G, Sulfonamides/pharmacology, Transcription, Up-Regulation/drug effects
Regulation of cholesterol 7 alpha-hydroxylase in the liver. Cloning, sequencing, and regulation of cholesterol 7 alpha-hydroxylase mRNA.
Tags: *Gene Expression Regulation, 1990, Amino Acid Sequence, Animals, Base Sequence, Cell Fractionation, Centrifugation, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/biosynthesis/*genetics/immunology, Cholestyramine Resin/pharmacology, Circadian Rhythm, Cloning, Cytochrome P-450 Enzyme System/genetics, Density Gradient, Department of Integrative Medical Sciences, DNA/genetics/isolation & purification, Enzyme Induction, Enzymologic, Epitopes/analysis, Female, Immunoblotting, Inbred Strains, Kinetics, Li Y C, Liver/drug effects/*enzymology, Messenger/*genetics, Molecular Sequence Data, Molecular/methods, NEOMED College of Medicine, Nucleic Acid, Polyribosomes/metabolism/ultrastructure, Rats, Restriction Mapping, RNA, Sequence Homology, Steroid Hydroxylases/*genetics, The Journal of biological chemistry, Wang D P
Regulation of cholesterol and bile acid homeostasis by the cholesterol 7alpha-hydroxylase/steroid response element-binding protein 2/microRNA-33a axis in mice.
Tags: 2013, Acetyl Coenzyme A/metabolism, Animal, Animals, Bile Acids and Salts/*metabolism, Boehme Shannon, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/genetics/*metabolism, Cholesterol/*metabolism, Department of Integrative Medical Sciences, Francl Jessica M, Hepatology (Baltimore, Md.), Homeostasis/*physiology, Knockout, Li Tiangang, Lipid Metabolism/physiology, Liver/metabolism, Male, Messenger/metabolism, Mice, MicroRNAs/*metabolism, Models, NEOMED College of Medicine, RNA, Signal Transduction/*physiology, Sterol Regulatory Element Binding Protein 2/*metabolism, Transgenic
Resveratrol inhibition of varicella-zoster virus replication in vitro.
Tags: 2006, Antiviral Agents/*pharmacology, Antiviral research, Bailey Erin, Blotting, Booth Tristan, Cell Line, Docherty John J, Dose-Response Relationship, Drug, Faith Seth A, Fibroblasts/virology, Herpesvirus 3, Human/*drug effects/physiology, Humans, Immediate-Early Proteins/biosynthesis, Messenger/biosynthesis, Resveratrol, Reverse Transcriptase Polymerase Chain Reaction, RNA, Stilbenes/*pharmacology, Sweet Thomas J, Trans-Activators/biosynthesis, Viral Envelope Proteins/biosynthesis, Viral Plaque Assay, Viral/biosynthesis, Virus Attachment/drug effects, Virus Inactivation/drug effects, Virus Replication/*drug effects, Western
Resveratrol suppresses nuclear factor-kappaB in herpes simplex virus infected cells.
Tags: 2006, Animals, Antiviral Agents/*pharmacology, Antiviral research, Bailey Erin, Booth Tristan, Cell Nucleus/chemistry, Cercopithecus aethiops, Cytoplasm/chemistry, DNA, Docherty John J, Electrophoretic Mobility Shift Assay, Faith Seth A, Fluorescence, Herpesvirus 1, Herpesvirus 2, Human/drug effects/genetics/*growth & development, Human/drug effects/genetics/*physiology, I-kappa B Proteins/metabolism, Messenger/biosynthesis, Microscopy, NF-kappa B/*metabolism, NF-KappaB Inhibitor alpha, Polymerase Chain Reaction, Resveratrol, Reverse Transcriptase Polymerase Chain Reaction, RNA, Stilbenes/*pharmacology, Sweet Thomas J, Transcription Factor RelA/metabolism, Vero Cells, Viral/biosynthesis, Virus Replication/*drug effects
Resveratrol suppresses oxidative stress and inflammatory response in diethylnitrosamine-initiated rat hepatocarcinogenesis.
Tags: 2010, Animals, Antioxidants/*pharmacology/therapeutic use, Antitumor, Barnes Kendra F, Bhatia Deepak, Bishayee Anupam, Cancer prevention research (Philadelphia, Pa.), Carcinogens/toxicity, Carroll Richard T, Chemical and Drug Induced Liver Injury/*etiology/metabolism/pathology, Darvesh Altaf S, Department of Pharmaceutical Sciences, Diethylnitrosamine/toxicity, Dose-Response Relationship, Drug, Drug Screening Assays, Enzyme Induction/drug effects, Experimental/chemically induced/metabolism/pathology/*prevention & control, Female, Hyperplasia, Inflammation/*prevention & control, Lipid Peroxidation/drug effects, Liver Neoplasms, Liver/drug effects/metabolism/pathology, Messenger/biosynthesis/genetics, NEOMED College of Pharmacy, NF-E2-Related Factor 2/biosynthesis/genetics, Nitric Oxide Synthase Type II/biosynthesis/genetics, Oxidative Stress/*drug effects, Phenobarbital/toxicity, Precancerous Conditions/*chemically induced/metabolism/pathology, Rats, Resveratrol, RNA, Sprague-Dawley, Stilbenes/*pharmacology/therapeutic use, Tyrosine/analogs & derivatives/analysis
Rifampicin induction of CYP3A4 requires pregnane X receptor cross talk with hepatocyte nuclear factor 4alpha and coactivators, and suppression of small heterodimer partner gene expression.
Tags: 2006, Antibiotics, Antitubercular/*pharmacology, Blotting, Cell Line, Chiang John Y L, Chromatin/metabolism, Cytochrome P-450 CYP3A, Cytochrome P-450 Enzyme System/*biosynthesis, Cytoplasmic and Nuclear/*biosynthesis/*drug effects/genetics, Department of Integrative Medical Sciences, Drug metabolism and disposition: the biological fate of chemicals, Electrophoretic Mobility Shift Assay, Enzyme Induction/drug effects, Glutathione Transferase/metabolism, Hepatocyte Nuclear Factor 4/genetics/*metabolism, Hepatocytes/drug effects/metabolism, Humans, Immunoprecipitation, Li Tiangang, Messenger/biosynthesis, NEOMED College of Medicine, Plasmids/genetics, Pregnane X Receptor, Receptor Cross-Talk/drug effects, Receptors, Reverse Transcriptase Polymerase Chain Reaction, Rifampin/*pharmacology, RNA, Steroid/*drug effects/genetics, Transfection, Tumor, Western
RNA interference for alpha-ENaC inhibits rat lung fluid absorption in vivo.
Tags: 2006, Absorption/drug effects, Adrenergic beta-Agonists/pharmacology, American journal of physiology. Lung cellular and molecular physiology, Amiloride/pharmacology, Animals, Body Fluids/*metabolism, Capillary Permeability, Dose-Response Relationship, Drug, Endothelium, Epithelial Cells/metabolism, Epithelial Sodium Channels, Epithelium/metabolism, Folkesson Hans G, Inhibitory Concentration 50, Li Tianbo, Lung/enzymology/*metabolism, Male, Messenger/antagonists & inhibitors/metabolism, Permeability, Plasmids/administration & dosage/pharmacology, Rats, RNA, Small Interfering/genetics/pharmacology, Sodium Channels/drug effects/genetics/metabolism/*physiology, Sprague-Dawley, Terbutaline/pharmacology, Tissue Distribution, Vascular/metabolism
RNA interference for CFTR attenuates lung fluid absorption at birth in rats.
Tags: *RNA Interference, 2008, Animals, Biological Transport/drug effects, Cells, Cultured, Cystic Fibrosis Transmembrane Conductance Regulator/*genetics/*metabolism, Epithelial Sodium Channels/genetics/metabolism, Female, Folkesson Hans G, Gene Expression Regulation/drug effects, Koshy Shyny, Li Tianbo, Lung/cytology/drug effects/*metabolism, Messenger/metabolism, Newborn, Pregnancy, Rats, Respiratory Mucosa/cytology/drug effects/metabolism, Respiratory research, RNA, Small Interfering/*pharmacology, Sprague-Dawley, Water/*metabolism
Sensory nerves and neuropeptides in uterine cervical ripening.
Tags: 2002, Animal, Animals, Calcitonin Gene-Related Peptide/biosynthesis, Capsaicin/pharmacology, Cervical Ripening/*metabolism, Cervix Uteri/*innervation/*metabolism, Collins J J, Complementary/metabolism, Department of Anatomy & Neurobiology, Female, Genetic, Immunohistochemistry, Labor, McCarson K E, Messenger/metabolism, NEOMED College of Medicine, Neurokinin-1/biosynthesis, Neurons/metabolism, Neuropeptides/*biosynthesis, Nitric Oxide Synthase/biosynthesis, Obstetric, Papka R E, Peptides, Plasmids/metabolism, Postpartum Period, Pregnancy, Rats, Receptors, RNA, Secretogranin II, Sprague-Dawley, Substance P/biosynthesis, Transcription, Usip S
Sequential activation of Elk-1/Egr-1/GADD45alpha by arsenic.
Tags: 2014, Arsenic/*pharmacology, Bhatia Deepak, Bishayee Anupam, Bronchi/cytology/drug effects/metabolism, Cell Cycle Proteins/biosynthesis/genetics/*metabolism, Cell Line, Early Growth Response Protein 1/biosynthesis/genetics/*metabolism, Epithelial Cells/drug effects/metabolism, ets-Domain Protein Elk-1/biosynthesis/genetics/*metabolism, Genetic, Humans, MAP Kinase Signaling System, Messenger/biosynthesis/genetics, Nuclear Proteins/biosynthesis/genetics/*metabolism, Oncotarget, Promoter Regions, Proto-Oncogene Proteins c-akt/metabolism, RNA, Shi Qiwen, Sutariya Vijaykumar
Serotonergic involvement in the regulation of prolactin and vasoactive intestinal peptide mRNA expression in the rat anterior pituitary.
Tags: 1994, 5-Hydroxytryptophan/pharmacology, alpha-Methyltyrosine, Animals, Anterior/*chemistry/drug effects/metabolism, Blotting, Bromocriptine/pharmacology, Carrillo A J, Gene Expression Regulation/drug effects/physiology, Genetic, Haloperidol/pharmacology, Ketanserin/pharmacology, Liu B, Male, Messenger/*analysis/genetics, Methiothepin/pharmacology, Methoxydimethyltryptamines/pharmacology, Methyltyrosines/pharmacology, Molecular and cellular endocrinology, Northern, Pituitary Gland, Prolactin/analysis/*genetics/metabolism, Quipazine/pharmacology, Rats, RNA, Serotonin/*physiology, Signs S A, Sprague-Dawley, Time Factors, Transcription, Vasoactive Intestinal Peptide/analysis/*genetics/metabolism, Wolford J
Substance P in the uterine cervix, dorsal root ganglia and spinal cord during pregnancy and the effect of estrogen on SP synthesis.
Tags: 2003, Afferent/metabolism, Amann R, Animals, Cervix Uteri/cytology/*metabolism, Department of Anatomy & Neurobiology, Down-Regulation, Estradiol/*analogs & derivatives/pharmacology, Estrogen/antagonists & inhibitors, Estrogens/*pharmacology, Female, Fulvestrant, Ganglia, Immunohistochemistry, In Situ Hybridization, Messenger/genetics/metabolism, Mowa C N, NEOMED College of Medicine, Neurons, Papka R, Peptides, Postpartum Period, Pregnancy/*metabolism, Radioimmunoassay, Rats, Receptors, Reverse Transcriptase Polymerase Chain Reaction, RNA, Spinal Cord/cytology/*metabolism, Spinal/cytology/*metabolism, Sprague-Dawley, Storey-Workley M, Substance P/*biosynthesis/genetics/metabolism, Up-Regulation, Usip S
Synthesis of radioactive single-stranded DNA probes using asymmetrical PCR and oligonucleotide random priming.
Tags: *DNA, *Oligonucleotides, *Phosphorus Radioisotopes, 1999, Animals, BioTechniques, Blotting, Cercopithecus aethiops, Deoxyribonuclease EcoRI, DNA, DNA Probes/*chemical synthesis, Genetic, Herpesvirus 1, Human/genetics, Isotope Labeling, Mao H, Messenger/analysis, Northern, Nucleic Acid Denaturation, Polymerase Chain Reaction/*methods, RNA, Rosenthal K S, Single-Stranded, Templates, Vero Cells, Viral/analysis
Testosterone Decreases 3 Beta-hydroxysteroid Dehydrogenase-isomerase Messenger Ribonucleic Acid In Cultured Mouse Leydig Cells By A Strain-specific Mechanism
Tags: 17-alpha-hydroxylase/c17-20 lyase, 1997, adult-rats, androgen, denovo synthesis, Endocrinology & Metabolism, expression, Heggland S J, human chorionic-gonadotropin, inbred mice, Journal Article or Conference Abstract Publication, Journal of Andrology, luteinizing-hormone, Receptor, RNA, side-chain cleavage, Signs S A, Stalvey J R D, steroidogenesis, testicular cells, testis