Browse Items (90 total)
- Tags: RNA
Valproate increases dopamine transporter expression through histone acetylation and enhanced promoter binding of Nurr1.
Tags: 2017, Acetylation/drug effects, Animals, Butyrates/pharmacology, Cell Line, Cell Survival/drug effects, Department of Pharmaceutical Sciences, Dopamine Plasma Membrane Transport Proteins/*metabolism, Dopamine transporter, Dopaminergic Neurons/cytology/drug effects/metabolism, Dose-Response Relationship, Drug, Eid Aseel, Epigenesis, Epigenetics, Genetic, Genetic/drug effects, Green Ashley L, Group A, Guo Grace L, HDAC, Histone deacetylase, Histone Deacetylase Inhibitors/*pharmacology, Histone Deacetylases/metabolism, Histones/*drug effects/metabolism, Homeodomain Proteins/metabolism, Hydroxamic Acids/pharmacology, Member 2/*metabolism, Messenger/metabolism, NEOMED College of Pharmacy, Neuropharmacology, Nuclear Receptor Subfamily 4, Nurr1, Pitx3, Promoter Regions, Rats, Richardson Jason R, RNA, Transcription Factors/metabolism, Valproate, Valproic Acid/*pharmacology, Zarbl Helmut, Zhan Le
Ultrastructural nucleolar alterations induced by an ametantrone–poly r(A-U) complex.
Tags: 1998, Antineoplastic Agents/*pharmacology, Authelet M, Carcinoma, Cell Nucleolus/*chemistry/drug effects/ultrastructure, Cultured/chemistry/drug effects/ultrastructure, DNA, Gilloteaux J, Goessens G, Humans, Immunoelectron, Jamison J M, Microscopy, Mitoxantrone/*analogs & derivatives/pharmacology, Neoplasm/*analysis, Neoplasm/analysis, Poly A-U/*pharmacology, Ribosomal/analysis, Ribosomal/analysis/ultrastructure, RNA, Summers J L, Thiry M, Tissue & cell, Transitional Cell, Tumor Cells, Urinary Bladder Neoplasms
TRPV4 channels mediate cardiac fibroblast differentiation by integrating mechanical and soluble signals.
Tags: *Calcium Signaling, *Cell Differentiation, *Mechanotransduction, 2013, Adapala Ravi K, Animals, Cellular, Chilian William M, Department of Integrative Medical Sciences, Extracellular Matrix/metabolism/physiology, Fibroblasts/*physiology, Gene Knockdown Techniques, Journal of molecular and cellular cardiology, Luther Daniel J, Male, Meszaros J Gary, Monoterpenes/pharmacology, Myocardium/cytology, Myofibroblasts/metabolism, NEOMED College of Medicine, Paruchuri Sailaja, Rats, RNA, Small Interfering/genetics, Sprague-Dawley, Thodeti Charles K, Thoppil Roslin J, Transforming Growth Factor beta1/physiology, TRPM Cation Channels/antagonists & inhibitors/metabolism, TRPV Cation Channels/genetics/*metabolism
The orphan nuclear receptor small heterodimer partner is required for thiazolidinedione effects in leptin-deficient mice.
Tags: 2015, Animals, Bile Acids and Salts/metabolism, Cytoplasmic and Nuclear/biosynthesis/*genetics/metabolism, Department of Integrative Medical Sciences, Diabetes Mellitus/*drug therapy/genetics/metabolism, Gene Expression Regulation/drug effects, Glucose/metabolism, Hepatocytes/drug effects, Humans, Insulin Resistance/genetics, Insulin/*metabolism, Journal of biomedical science, Lee Yoon-Kwang, Leptin/deficiency/genetics, Lipid Metabolism/drug effects, Messenger/genetics, Mice, Moore David D, NEOMED College of Medicine, Obese, Park Young Joo, PPAR gamma/*biosynthesis/genetics, Receptors, RNA, Thiazolidinediones/*administration & dosage, Tseng Hsiu-Ting
The nucleotide sequence of rabbit liver cytochrome b5 mRNA.
Tags: 1988, Amino Acid Sequence, Animals, Base Sequence, Chromosome Deletion, Cloning, Cytochrome b Group/*genetics, Cytochromes b5, Dariush N, Fisher C W, Genes, Liver/*metabolism, Messenger/*genetics, Molecular, Molecular Sequence Data, Protein sequences & data analysis, Rabbits, RNA, Steggles A W
The large protein 'L' of Peste-des-petits-ruminants virus exhibits RNA triphosphatase activity, the first enzyme in mRNA capping pathway.
Tags: 2019, Acid Anhydride Hydrolases/*metabolism, Animals, Ansari Mohammad Yunus, Baculoviridae/genetics, Bellur Asutosh, Cercopithecus aethiops, Cloning, Conventional mRNA capping, Department of Anatomy & Neurobiology, Enzyme Activation, Gene Expression, Genetic Vectors/genetics, Messenger/*genetics/*metabolism, Molecular, Morbillivirus, mRNA capping, NEOMED College of Medicine, Peste-des-petits-ruminants virus L protein, Peste-des-petits-ruminants virus/*physiology, Peste-des-Petits-Ruminants/*virology, PPRV, Rajagopalan Deepa, RNA, RNA Caps/*metabolism, RNA triphosphatase, Shaila Melkote Subbarao, Shanmugam Purnima, Singh Piyush Kumar, Vero Cells, Viral Proteins/*metabolism, Virus Genes
The isolation and characterization of the human cytochrome b5 gene.
Tags: 1995, Animals, Base Sequence, Biochemical and biophysical research communications, Cattle, Cell Line, Cloning, Cosmids, Cultured, Cytochromes b5/biosynthesis/*genetics, DNA Primers, DNA/genetics/isolation & purification, Gene Library, Genetic, Giordano S J, Hominidae/*genetics, Humans, Introns, Li X R, Luciferases/biosynthesis, Messenger/analysis/biosynthesis, Molecular, Molecular Sequence Data, Polymerase Chain Reaction, Promoter Regions, Rabbits, RNA, Steggles A W, Transfection, Tumor Cells, Yoo M
The isolation and characterization of the bovine cytochrome b5 gene, and a transcribed pseudogene.
Tags: *Pseudogenes, 1993, Amino Acid Sequence, Animals, Base Sequence, Blotting, Cattle/*genetics, Cristiano R J, Cytochromes b5/*genetics, DNA/genetics/isolation & purification, Exons, Gene Expression, Genetic, Genomic Library, Genomics, Giordano S J, Humans, Introns, Messenger/biosynthesis/metabolism, Molecular Sequence Data, Nucleic Acid, Nucleic Acid Conformation, Oligodeoxyribonucleotides, Rabbits, Restriction Mapping, Reticulocytes/metabolism, RNA, RNA Precursors/chemistry/metabolism, Sequence Homology, Southern, Steggles A W, Transcription
The glycoprotein GPNMB attenuates astrocyte inflammatory responses through the CD44 receptor.
Tags: *Neuroinflammation, *Parkinson's disease, 1-Methyl-4-phenyl-1, 2, 2018, 3, 6-tetrahydropyridine/pharmacology, Analysis of Variance, Animals, Anti-Inflammatory Agents/*therapeutic use, Astrocyte, Astrocytes/*drug effects, Boyle Alexa M, Budge Kevin M, Case-Control Studies, CD44, Cells, Chemical, Cultured, Cytokines/genetics/metabolism, Databases, Female, Glial Fibrillary Acidic Protein/metabolism, GPNMB, Humans, Hyaluronan Receptors/*metabolism, Inflammation/*drug therapy/etiology, Journal of neuroinflammation, Male, Membrane Glycoproteins/*therapeutic use, Messenger/metabolism, Mice, Neal Matthew L, Neurotoxins/toxicity, Nitric Oxide/metabolism, Parkinson Disease/complications/*pathology, Reactive Oxygen Species/metabolism, Richardson Jason R, RNA, Safadi Fayez F, Signal Transduction/drug effects
The effects of pregnancy and estrogen on the expression of calcitonin gene-related peptide (CGRP) in the uterine cervix, dorsal root ganglia and spinal cord.
Tags: 2003, Animals, Calcitonin Gene-Related Peptide/analysis/biosynthesis/*genetics, Cervix Uteri/*physiology, Collins J, Department of Anatomy & Neurobiology, Estrogens/*physiology, Female, Ganglia, Hargreaves K M, Immunohistochemistry, In Situ Hybridization, Messenger/metabolism, Mowa C N, NEOMED College of Medicine, Papka R E, Peptides, Pregnancy, Radioimmunoassay, Rats, RNA, Spinal Cord/*physiology, Spinal/*physiology, Sprague-Dawley, Storey-Workley M, Usip S
The complete nucleotide sequence of human liver cytochrome b5 mRNA.
The antiviral activity of RNA-dye combinations.
Testosterone Decreases 3 Beta-hydroxysteroid Dehydrogenase-isomerase Messenger Ribonucleic Acid In Cultured Mouse Leydig Cells By A Strain-specific Mechanism
Tags: 17-alpha-hydroxylase/c17-20 lyase, 1997, adult-rats, androgen, denovo synthesis, Endocrinology & Metabolism, expression, Heggland S J, human chorionic-gonadotropin, inbred mice, Journal Article or Conference Abstract Publication, Journal of Andrology, luteinizing-hormone, Receptor, RNA, side-chain cleavage, Signs S A, Stalvey J R D, steroidogenesis, testicular cells, testis
Synthesis of radioactive single-stranded DNA probes using asymmetrical PCR and oligonucleotide random priming.
Tags: *DNA, *Oligonucleotides, *Phosphorus Radioisotopes, 1999, Animals, BioTechniques, Blotting, Cercopithecus aethiops, Deoxyribonuclease EcoRI, DNA, DNA Probes/*chemical synthesis, Genetic, Herpesvirus 1, Human/genetics, Isotope Labeling, Mao H, Messenger/analysis, Northern, Nucleic Acid Denaturation, Polymerase Chain Reaction/*methods, RNA, Rosenthal K S, Single-Stranded, Templates, Vero Cells, Viral/analysis
Substance P in the uterine cervix, dorsal root ganglia and spinal cord during pregnancy and the effect of estrogen on SP synthesis.
Tags: 2003, Afferent/metabolism, Amann R, Animals, Cervix Uteri/cytology/*metabolism, Department of Anatomy & Neurobiology, Down-Regulation, Estradiol/*analogs & derivatives/pharmacology, Estrogen/antagonists & inhibitors, Estrogens/*pharmacology, Female, Fulvestrant, Ganglia, Immunohistochemistry, In Situ Hybridization, Messenger/genetics/metabolism, Mowa C N, NEOMED College of Medicine, Neurons, Papka R, Peptides, Postpartum Period, Pregnancy/*metabolism, Radioimmunoassay, Rats, Receptors, Reverse Transcriptase Polymerase Chain Reaction, RNA, Spinal Cord/cytology/*metabolism, Spinal/cytology/*metabolism, Sprague-Dawley, Storey-Workley M, Substance P/*biosynthesis/genetics/metabolism, Up-Regulation, Usip S
Serotonergic involvement in the regulation of prolactin and vasoactive intestinal peptide mRNA expression in the rat anterior pituitary.
Tags: 1994, 5-Hydroxytryptophan/pharmacology, alpha-Methyltyrosine, Animals, Anterior/*chemistry/drug effects/metabolism, Blotting, Bromocriptine/pharmacology, Carrillo A J, Gene Expression Regulation/drug effects/physiology, Genetic, Haloperidol/pharmacology, Ketanserin/pharmacology, Liu B, Male, Messenger/*analysis/genetics, Methiothepin/pharmacology, Methoxydimethyltryptamines/pharmacology, Methyltyrosines/pharmacology, Molecular and cellular endocrinology, Northern, Pituitary Gland, Prolactin/analysis/*genetics/metabolism, Quipazine/pharmacology, Rats, RNA, Serotonin/*physiology, Signs S A, Sprague-Dawley, Time Factors, Transcription, Vasoactive Intestinal Peptide/analysis/*genetics/metabolism, Wolford J
Sequential activation of Elk-1/Egr-1/GADD45alpha by arsenic.
Tags: 2014, Arsenic/*pharmacology, Bhatia Deepak, Bishayee Anupam, Bronchi/cytology/drug effects/metabolism, Cell Cycle Proteins/biosynthesis/genetics/*metabolism, Cell Line, Early Growth Response Protein 1/biosynthesis/genetics/*metabolism, Epithelial Cells/drug effects/metabolism, ets-Domain Protein Elk-1/biosynthesis/genetics/*metabolism, Genetic, Humans, MAP Kinase Signaling System, Messenger/biosynthesis/genetics, Nuclear Proteins/biosynthesis/genetics/*metabolism, Oncotarget, Promoter Regions, Proto-Oncogene Proteins c-akt/metabolism, RNA, Shi Qiwen, Sutariya Vijaykumar
Sensory nerves and neuropeptides in uterine cervical ripening.
Tags: 2002, Animal, Animals, Calcitonin Gene-Related Peptide/biosynthesis, Capsaicin/pharmacology, Cervical Ripening/*metabolism, Cervix Uteri/*innervation/*metabolism, Collins J J, Complementary/metabolism, Department of Anatomy & Neurobiology, Female, Genetic, Immunohistochemistry, Labor, McCarson K E, Messenger/metabolism, NEOMED College of Medicine, Neurokinin-1/biosynthesis, Neurons/metabolism, Neuropeptides/*biosynthesis, Nitric Oxide Synthase/biosynthesis, Obstetric, Papka R E, Peptides, Plasmids/metabolism, Postpartum Period, Pregnancy, Rats, Receptors, RNA, Secretogranin II, Sprague-Dawley, Substance P/biosynthesis, Transcription, Usip S
RNA interference for CFTR attenuates lung fluid absorption at birth in rats.
Tags: *RNA Interference, 2008, Animals, Biological Transport/drug effects, Cells, Cultured, Cystic Fibrosis Transmembrane Conductance Regulator/*genetics/*metabolism, Epithelial Sodium Channels/genetics/metabolism, Female, Folkesson Hans G, Gene Expression Regulation/drug effects, Koshy Shyny, Li Tianbo, Lung/cytology/drug effects/*metabolism, Messenger/metabolism, Newborn, Pregnancy, Rats, Respiratory Mucosa/cytology/drug effects/metabolism, Respiratory research, RNA, Small Interfering/*pharmacology, Sprague-Dawley, Water/*metabolism
RNA interference for alpha-ENaC inhibits rat lung fluid absorption in vivo.
Tags: 2006, Absorption/drug effects, Adrenergic beta-Agonists/pharmacology, American journal of physiology. Lung cellular and molecular physiology, Amiloride/pharmacology, Animals, Body Fluids/*metabolism, Capillary Permeability, Dose-Response Relationship, Drug, Endothelium, Epithelial Cells/metabolism, Epithelial Sodium Channels, Epithelium/metabolism, Folkesson Hans G, Inhibitory Concentration 50, Li Tianbo, Lung/enzymology/*metabolism, Male, Messenger/antagonists & inhibitors/metabolism, Permeability, Plasmids/administration & dosage/pharmacology, Rats, RNA, Small Interfering/genetics/pharmacology, Sodium Channels/drug effects/genetics/metabolism/*physiology, Sprague-Dawley, Terbutaline/pharmacology, Tissue Distribution, Vascular/metabolism
Rifampicin induction of CYP3A4 requires pregnane X receptor cross talk with hepatocyte nuclear factor 4alpha and coactivators, and suppression of small heterodimer partner gene expression.
Tags: 2006, Antibiotics, Antitubercular/*pharmacology, Blotting, Cell Line, Chiang John Y L, Chromatin/metabolism, Cytochrome P-450 CYP3A, Cytochrome P-450 Enzyme System/*biosynthesis, Cytoplasmic and Nuclear/*biosynthesis/*drug effects/genetics, Department of Integrative Medical Sciences, Drug metabolism and disposition: the biological fate of chemicals, Electrophoretic Mobility Shift Assay, Enzyme Induction/drug effects, Glutathione Transferase/metabolism, Hepatocyte Nuclear Factor 4/genetics/*metabolism, Hepatocytes/drug effects/metabolism, Humans, Immunoprecipitation, Li Tiangang, Messenger/biosynthesis, NEOMED College of Medicine, Plasmids/genetics, Pregnane X Receptor, Receptor Cross-Talk/drug effects, Receptors, Reverse Transcriptase Polymerase Chain Reaction, Rifampin/*pharmacology, RNA, Steroid/*drug effects/genetics, Transfection, Tumor, Western
Resveratrol suppresses oxidative stress and inflammatory response in diethylnitrosamine-initiated rat hepatocarcinogenesis.
Tags: 2010, Animals, Antioxidants/*pharmacology/therapeutic use, Antitumor, Barnes Kendra F, Bhatia Deepak, Bishayee Anupam, Cancer prevention research (Philadelphia, Pa.), Carcinogens/toxicity, Carroll Richard T, Chemical and Drug Induced Liver Injury/*etiology/metabolism/pathology, Darvesh Altaf S, Department of Pharmaceutical Sciences, Diethylnitrosamine/toxicity, Dose-Response Relationship, Drug, Drug Screening Assays, Enzyme Induction/drug effects, Experimental/chemically induced/metabolism/pathology/*prevention & control, Female, Hyperplasia, Inflammation/*prevention & control, Lipid Peroxidation/drug effects, Liver Neoplasms, Liver/drug effects/metabolism/pathology, Messenger/biosynthesis/genetics, NEOMED College of Pharmacy, NF-E2-Related Factor 2/biosynthesis/genetics, Nitric Oxide Synthase Type II/biosynthesis/genetics, Oxidative Stress/*drug effects, Phenobarbital/toxicity, Precancerous Conditions/*chemically induced/metabolism/pathology, Rats, Resveratrol, RNA, Sprague-Dawley, Stilbenes/*pharmacology/therapeutic use, Tyrosine/analogs & derivatives/analysis
Resveratrol suppresses nuclear factor-kappaB in herpes simplex virus infected cells.
Tags: 2006, Animals, Antiviral Agents/*pharmacology, Antiviral research, Bailey Erin, Booth Tristan, Cell Nucleus/chemistry, Cercopithecus aethiops, Cytoplasm/chemistry, DNA, Docherty John J, Electrophoretic Mobility Shift Assay, Faith Seth A, Fluorescence, Herpesvirus 1, Herpesvirus 2, Human/drug effects/genetics/*growth & development, Human/drug effects/genetics/*physiology, I-kappa B Proteins/metabolism, Messenger/biosynthesis, Microscopy, NF-kappa B/*metabolism, NF-KappaB Inhibitor alpha, Polymerase Chain Reaction, Resveratrol, Reverse Transcriptase Polymerase Chain Reaction, RNA, Stilbenes/*pharmacology, Sweet Thomas J, Transcription Factor RelA/metabolism, Vero Cells, Viral/biosynthesis, Virus Replication/*drug effects
Resveratrol inhibition of varicella-zoster virus replication in vitro.
Tags: 2006, Antiviral Agents/*pharmacology, Antiviral research, Bailey Erin, Blotting, Booth Tristan, Cell Line, Docherty John J, Dose-Response Relationship, Drug, Faith Seth A, Fibroblasts/virology, Herpesvirus 3, Human/*drug effects/physiology, Humans, Immediate-Early Proteins/biosynthesis, Messenger/biosynthesis, Resveratrol, Reverse Transcriptase Polymerase Chain Reaction, RNA, Stilbenes/*pharmacology, Sweet Thomas J, Trans-Activators/biosynthesis, Viral Envelope Proteins/biosynthesis, Viral Plaque Assay, Viral/biosynthesis, Virus Attachment/drug effects, Virus Inactivation/drug effects, Virus Replication/*drug effects, Western
Regulation of cholesterol and bile acid homeostasis by the cholesterol 7alpha-hydroxylase/steroid response element-binding protein 2/microRNA-33a axis in mice.
Tags: 2013, Acetyl Coenzyme A/metabolism, Animal, Animals, Bile Acids and Salts/*metabolism, Boehme Shannon, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/genetics/*metabolism, Cholesterol/*metabolism, Department of Integrative Medical Sciences, Francl Jessica M, Hepatology (Baltimore, Md.), Homeostasis/*physiology, Knockout, Li Tiangang, Lipid Metabolism/physiology, Liver/metabolism, Male, Messenger/metabolism, Mice, MicroRNAs/*metabolism, Models, NEOMED College of Medicine, RNA, Signal Transduction/*physiology, Sterol Regulatory Element Binding Protein 2/*metabolism, Transgenic
Regulation of cholesterol 7 alpha-hydroxylase in the liver. Cloning, sequencing, and regulation of cholesterol 7 alpha-hydroxylase mRNA.
Tags: *Gene Expression Regulation, 1990, Amino Acid Sequence, Animals, Base Sequence, Cell Fractionation, Centrifugation, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/biosynthesis/*genetics/immunology, Cholestyramine Resin/pharmacology, Circadian Rhythm, Cloning, Cytochrome P-450 Enzyme System/genetics, Density Gradient, Department of Integrative Medical Sciences, DNA/genetics/isolation & purification, Enzyme Induction, Enzymologic, Epitopes/analysis, Female, Immunoblotting, Inbred Strains, Kinetics, Li Y C, Liver/drug effects/*enzymology, Messenger/*genetics, Molecular Sequence Data, Molecular/methods, NEOMED College of Medicine, Nucleic Acid, Polyribosomes/metabolism/ultrastructure, Rats, Restriction Mapping, RNA, Sequence Homology, Steroid Hydroxylases/*genetics, The Journal of biological chemistry, Wang D P
PXR induces CYP27A1 and regulates cholesterol metabolism in the intestine.
Tags: *Lipid Metabolism, 2007, ATP Binding Cassette Transporter, ATP Binding Cassette Transporter 1, ATP-Binding Cassette Transporters/genetics, Base Sequence, Cell Line, Chen Wenling, Chiang John Y L, Cholestanetriol 26-Monooxygenase/*metabolism, Cholesterol, Cholesterol/*metabolism, Department of Integrative Medical Sciences, Fluorinated, Genes, Genetic/drug effects, Genetic/genetics, HDL/metabolism, Hepatocytes/drug effects/enzymology/metabolism, Humans, Hydrocarbons, Hydroxycholesterols/metabolism/pharmacology, Intestinal Mucosa/metabolism, Intestines/cytology/drug effects/enzymology, Journal of lipid research, Li Tiangang, Member 1, Messenger/genetics/metabolism, Molecular Sequence Data, NEOMED College of Medicine, Pregnane X Receptor, Promoter Regions, Receptors, Reporter, Response Elements/genetics, Rifampin/pharmacology, RNA, Steroid/*metabolism, Subfamily G, Sulfonamides/pharmacology, Transcription, Up-Regulation/drug effects
Para-chlorophenylalanine treatment inhibits the expression of vasoactive intestinal peptide messenger RNA in rat anterior pituitary.
Tags: 1993, alpha-Methyltyrosine, Animals, Anterior/*drug effects/metabolism, Brain research. Molecular brain research, Carrillo A J, Chemical, Depression, Dluzen D E, Dopamine/metabolism, Fenclonine/*pharmacology, Gene Expression Regulation/drug effects, Male, Messenger/*biosynthesis, Methyltyrosines/pharmacology, Pituitary Gland, Prolactin/metabolism, Rats, RNA, Serotonin/metabolism, Signs S A, Sprague-Dawley, Tryptophan Hydroxylase/antagonists & inhibitors, Vasoactive Intestinal Peptide/*biosynthesis/genetics
Osteoactivin regulates head and neck squamous cell carcinoma invasion by modulating matrix metalloproteases.
Tags: *Cell Movement, 2018, Arosarena Oneida A, Barr Eric W, Carcinoma, Cell Line, cell lines, Department of Anatomy & Neurobiology, Enzymologic, Extracellular Matrix, Gene Expression Regulation, Head and Neck Neoplasms/*enzymology/genetics/pathology, Human, Humans, Journal of cellular physiology, matrix metalloproteinases, Membrane Glycoproteins/genetics/*metabolism, Messenger/genetics/metabolism, NEOMED College of Medicine, neoplasm invasion, Neoplasm Invasiveness, Neoplastic, RNA, RNA Interference, Safadi Fayez F, Secreted/genetics/*metabolism, Signal Transduction, Squamous Cell Carcinoma of Head and Neck, Squamous Cell/*enzymology/genetics/pathology, Tarr Joseph T, Thorpe Ryan, Transfection, Tumor, Yankey Hilary
Osteoactivin Promotes Migration of Oral Squamous Cell Carcinomas.
Tags: *Cell Movement, 2016, Arosarena Oneida A, Barr Eric W, Bryant Evan, Carcinoma, Cell Adhesion, Cell Line, Cell Proliferation, Cell Survival, Dela Cadena Raul A, Denny Michael F, Department of Anatomy & Neurobiology, Enzyme Activation, Gene Expression Regulation, Head and Neck Neoplasms/genetics/*metabolism/pathology, Humans, Integrin beta1/metabolism, Journal of cellular physiology, Membrane Glycoproteins/genetics/*metabolism, Messenger/metabolism, Mitogen-Activated Protein Kinases/metabolism, Mouth Neoplasms/genetics/*metabolism/pathology, NEOMED College of Medicine, Neoplasm Invasiveness, Neoplastic, Protein Binding, RNA, RNA Interference, Safadi Fayez F, Signal Transduction, Squamous Cell Carcinoma of Head and Neck, Squamous Cell/genetics/*metabolism/pathology, Thorpe Ryan, Time Factors, Transfection, Tumor
On the mechanism of bile acid inhibition of rat sterol 12alpha-hydroxylase gene (CYP8B1) transcription: roles of alpha-fetoprotein transcription factor and hepatocyte nuclear factor 4alpha.
Tags: *DNA-Binding Proteins, 2002, alpha-Fetoproteins/genetics/*physiology, Animals, Base Sequence, Bile Acids and Salts/*pharmacology, Biochimica et biophysica acta, Cattle, Chiang John Y L, Cytochrome P-450 Enzyme System/*genetics, Department of Integrative Medical Sciences, DNA, Eggertsen Gosta, Enzymologic/*drug effects/physiology, Gene Expression Regulation, Genetic, Genetic/*drug effects, Hepatocyte Nuclear Factor 4, Messenger/genetics, NEOMED College of Medicine, Phosphoproteins/genetics/*physiology, Promoter Regions, Rats, RNA, Sprague-Dawley, Steroid 12-alpha-Hydroxylase, Steroid Hydroxylases/*genetics, Transcription, Transcription Factors/genetics/*physiology, Yang Yizeng, Zhang Ming
Obesity-associated decrease in growth hormone-releasing hormone gene expression: a mechanism for reduced growth hormone mRNA levels in genetically obese Zucker rats.
Tags: *Gene Expression, 1993, Ahmad I, Animals, Blotting, Downs T R, Finkelstein J A, Frohman L A, Growth Hormone-Releasing Hormone/*genetics, Growth Hormone/blood/*genetics/metabolism, Male, Messenger/*metabolism, Neuroendocrinology, Northern, Obesity/*metabolism, Pituitary Gland/metabolism, Rats, RNA, Zucker
Obesity- and sex-related alterations in growth hormone messenger RNA levels.
Tags: 1989, Ahmad I, Animals, Carrillo A J, DNA Probes, Female, Finkelstein J A, Male, Messenger/metabolism, Molecular and cellular endocrinology, Nucleic Acid Hybridization, Obesity/*genetics/metabolism, Prolactin/genetics, Rats, RNA, Sex Characteristics, Somatomedins/*genetics, Steggles A W, Zucker
Nuclear receptor-mediated repression of human cholesterol 7alpha-hydroxylase gene transcription by bile acids.
Tags: *Hydroxysteroid Dehydrogenases, *Membrane Glycoproteins, 2001, Animals, Bile Acids and Salts/*pharmacology, Caco-2 Cells, Carrier Proteins/genetics/physiology, Cell Line, Chen W, Chiang J Y, CHO Cells, Cholesterol 7-alpha-Hydroxylase/*genetics, Cricetinae, Cultured, Cytoplasmic and Nuclear/genetics/*physiology, Department of Integrative Medical Sciences, DNA-Binding Proteins/drug effects/genetics/physiology, DNA/metabolism, Embryo, Gene Expression/*drug effects, Genetic, Genetic/drug effects, Humans, Journal of lipid research, Kidney, Liver/metabolism, Luciferases/genetics, Mammalian, Messenger/analysis, NEOMED College of Medicine, Owsley E, Promoter Regions, Rats, Receptors, Recombinant Fusion Proteins/metabolism, Retinoic Acid/genetics/physiology, Retinoid X Receptors, Reverse Transcriptase Polymerase Chain Reaction, RNA, Stroup D, Taurocholic Acid/pharmacology, Transcription, Transcription Factors/drug effects/genetics/physiology, Transfection, Tumor Cells, Yang Y
Modulation of ten-eleven translocation 1 (TET1), Isocitrate Dehydrogenase (IDH) expression, alpha-Ketoglutarate (alpha-KG), and DNA hydroxymethylation levels by interleukin-1beta in primary human chondrocytes.
Tags: *DNA methylation, *Epigenesis, 2014, 5-hmC, 5-Methylcytosine/analogs & derivatives, Chondrocytes, Chondrocytes/chemistry/*metabolism, Cytokine, Cytosine/*analogs & derivatives/analysis/metabolism, Department of Anatomy & Neurobiology, Dioxygenase, DNA Methylation, DNA-Binding Proteins/*biosynthesis/genetics, Epigenetics, Genetic, Haqqi Tariq M, Haseeb Abdul, Humans, IL-1, Interleukin-1beta/pharmacology/*physiology, Isocitrate Dehydrogenase/*biosynthesis/genetics, Ketoglutaric Acids/*metabolism, Makki Mohammad Shahidul, Messenger/biosynthesis/genetics, Mixed Function Oxygenases, NEOMED College of Medicine, Primary Cell Culture, Proto-Oncogene Proteins/*biosynthesis/genetics, RNA, The Journal of biological chemistry, TNF-alpha, Tumor Necrosis Factor-alpha/pharmacology/physiology
Modulation of olfactory bulb tyrosine hydroxylase and catecholamine transporter mRNA by estrogen.
Tags: *Membrane Glycoproteins, *Nerve Tissue Proteins, 2002, Animals, Brain research. Molecular brain research, Delayed-Action Preparations, Dluzen Dean E, Dopamine Plasma Membrane Transport Proteins, Drug Combinations, Estrogen Antagonists/administration & dosage, Estrogens/administration & dosage/*pharmacology, Female, Inbred Strains, Kim Kyungjin, Membrane Transport Proteins/*genetics/metabolism, Messenger/*metabolism, Mice, Molecular Sequence Data, Norepinephrine Plasma Membrane Transport Proteins, Olfactory Bulb/*drug effects/enzymology/*physiology, Ovariectomy, Park June-Hee, Rats, RNA, Symporters/*genetics/metabolism, Tyrosine 3-Monooxygenase/*genetics/metabolism
MiR-21 enhances melanoma invasiveness via inhibition of tissue inhibitor of metalloproteinases 3 expression: in vivo effects of MiR-21 inhibitor.
Tags: 2015, Carson Mary, Carson William E 3rd, Cell Line, Cell Movement/genetics, Cell Proliferation/genetics, Chan Anthony N, Dao Thao-Vi, Fairchild Ene T, Ganju Akaansha, Gene Expression Regulation, Grignol Valerie P, Humans, Jaime-Ramirez Alena Cristina, Karpa Volodymyr I, Latchana Nicholas, Levine Kala M, Martin del Campo Sara E, Melanoma/*genetics/metabolism/pathology, MicroRNAs/*genetics/metabolism, Neoplasm Invasiveness/*genetics/pathology, Neoplastic, PloS one, RNA, Skin Neoplasms/*genetics/metabolism/pathology, Small Interfering, Tissue Inhibitor of Metalloproteinase-3/*genetics/metabolism, Tumor
miR-139 modulates MCPIP1/IL-6 expression and induces apoptosis in human OA chondrocytes.
Tags: *Apoptosis, 2015, 3' Untranslated Regions, Aged, Chondrocytes/*metabolism/pathology, Department of Anatomy & Neurobiology, Down-Regulation, Experimental & molecular medicine, Female, Gene Expression Regulation, Haqqi Tariq M, Humans, Interleukin-6/*genetics, Makki Mohammad Shahidul, Male, Messenger/genetics, MicroRNAs/*genetics, Middle Aged, NEOMED College of Medicine, Osteoarthritis/*genetics/pathology, Ribonucleases/*genetics, RNA, Transcription Factors/*genetics, Up-Regulation