Browse Items (328 total)
- Tags: Department of Integrative Medical Sciences
coronary circulation in acute myocardial ischaemia/reperfusion injury: a target for cardioprotection.
Tags: 2019, acute coronary syndromes, blood capillaries, cardiac myocytes, cardiac vasculature, cardioprotection, Cardiovascular research, Chilian William, Coronary Circulation, Crea Filippo, CYTOLOGY, Davidson Sean M, Department of Integrative Medical Sciences, Edema, Endothelium, erythrocytes, Ferdinandy Peter, Garcia-Dorado David, Hausenloy Derek J, Hemorrhage, Heusch Gerd, Infarction, Ischaemia, ischemia, Ischemic Preconditioning, June 2019 Update, LEUKOCYTES, MEDICAL sciences, Microvascular obstruction, midventricular obstruction, Myocardial Reperfusion, NEOMED College of Medicine, personal integrity, pharmacology, physiologic reperfusion, PRASUGREL, Reperfusion, Reperfusion Injury, reperfusion therapy, Schulz Rainer, van Royen Niels
Coronary collateral growth–back to the future.
Tags: 2012, Chilian William M, Collateral Circulation/*physiology, Coronary Artery Disease/physiopathology/therapy, Coronary Circulation/physiology, Department of Integrative Medical Sciences, Dong Feng, Humans, Journal of molecular and cellular cardiology, Logan Suzanna, Mayorga Maritza, Myocardial Ischemia/physiopathology/therapy, NEOMED College of Medicine, Neovascularization, Ohanyan Vahagn, Penn Marc S, Physiologic/physiology, Pung Yuh Fen, Yin Liya
Coronary microvascular Kv1 channels as regulatory sensors of intracellular pyridine nucleotide redox potential.
Tags: * NADH, *endothelium, *ion channels, *vascular smooth muscle, *vasodilation, 2018, Animals, Coronary Vessels/chemistry, Department of Integrative Medical Sciences, Dwenger Marc M, Humans, Microcirculation, Microcirculation (New York, N.Y. : 1994), Navedo Manuel F, NEOMED College of Medicine, Nystoriak Matthew A, Ohanyan Vahagn, Oxidation-Reduction, Potassium Channels, Pyrimidine Nucleotides/*metabolism, Reactive Nitrogen Species/metabolism, Reactive Oxygen Species/metabolism, Voltage-Gated/*physiology
Corruption of coronary collateral growth in metabolic syndrome: Role of oxidative stress.
Crystal Diagnostics Xpress() LM Kit for the Rapid Detection of Listeria monocytogenes from Environmental Surfaces.
Tags: *Reagent Kits, 2017, Bullard Brian, Ceramics, Department of Integrative Medical Sciences, Diagnostic, Journal of AOAC International, Kuzenko-Hentosh Stephanie, Listeria monocytogenes/*isolation & purification, NEOMED College of Medicine, Niehaus Gary D, Plastics, Sensitivity and Specificity, Stainless Steel, Stumpf Curtis H, Zhoa Weidong
Cysteinyl leukotriene 2 receptor promotes endothelial permeability, tumor angiogenesis, and metastasis.
Tags: *angiogenesis, *cysteinyl leukotriene receptors, *endothelial cells, *metastasis, *tumor growth, 2019, Adapala Ravi K, Austen K Frank, Department of Integrative Medical Sciences, Duah Ernest, Kanaoka Yoshihide, Keshamouni Venkateshwar G, Kondeti Vinay, NEOMED College of Medicine, Paruchuri Sailaja, Proceedings of the National Academy of Sciences of the United States of America, Teegala Lakshminarayan Reddy, Thodeti Charles K
Cysteinyl leukotriene 2 receptor promotes endothelial permeability, tumor angiogenesis, and metastasis.
Tags: *angiogenesis, *cysteinyl leukotriene receptors, *endothelial cells, *metastasis, *tumor growth, 2019, Adapala Ravi K, Animals, Austen K Frank, Capillary Permeability/drug effects, Cyclohexanecarboxylic Acids/pharmacology, Department of Integrative Medical Sciences, Duah Ernest, Endothelial Cells/*drug effects, Experimental, Gene Knockout Techniques, Inbred C57BL, Kanaoka Yoshihide, Keshamouni Venkateshwar G, Kondeti Vinay, Leukotriene Antagonists/pharmacology, Leukotriene/drug effects/*metabolism, Lung Neoplasms/drug therapy, Male, Mice, NEOMED College of Medicine, Neoplasm Metastasis/drug therapy, Neoplasm Transplantation, Neoplasms, Neovascularization, Paruchuri Sailaja, Pathologic/*chemically induced/drug therapy, Phthalic Acids/pharmacology, Proceedings of the National Academy of Sciences of the United States of America, Receptors, Teegala Lakshminarayan Reddy, Thodeti Charles K
Cytochrome P450 omega hydroxylase (CYP4) function in fatty acid metabolism and metabolic diseases.
Tags: *Cytochrome P-450 Enzyme System/genetics/metabolism/physiology, 2008, Animals, Biochemical pharmacology, Cytochrome P-450 CYP4A/genetics/metabolism/physiology, Department of Integrative Medical Sciences, Enzymologic, Fatty Acids/*metabolism, Gene Expression Regulation, Hardwick James P, Humans, Metabolic Diseases/enzymology/*metabolism, NEOMED College of Medicine
Cytokine regulation of human sterol 12alpha-hydroxylase (CYP8B1) gene.
Tags: 2005, American journal of physiology. Gastrointestinal and liver physiology, Cell Line, Chenodeoxycholic Acid/pharmacology, Chiang John Y L, Chromosome Mapping, Department of Integrative Medical Sciences, DNA-Binding Proteins/genetics/metabolism, Enzyme Inhibitors/pharmacology, Gene Expression Regulation/*drug effects, Genetic/drug effects, Genetic/physiology, Hepatocyte Nuclear Factor 4, Hepatocytes/metabolism, Humans, Interleukin-1/*pharmacology, Jahan Asmeen, MAP Kinase Signaling System/drug effects/physiology, Messenger/antagonists & inhibitors, Mitogen-Activated Protein Kinase 8/metabolism, Mitogen-Activated Protein Kinases/antagonists & inhibitors, NEOMED College of Medicine, Phosphoproteins/genetics/metabolism, Phosphorylation, Promoter Regions, Response Elements/genetics, RNA, Steroid 12-alpha-Hydroxylase/antagonists & inhibitors/*genetics, Transcription, Transcription Factors/genetics/metabolism
Deficiency of both farnesoid X receptor and Takeda G protein-coupled receptor 5 exacerbated liver fibrosis in mice.
Deficiency of cholesterol 7alpha-hydroxylase in bile acid synthesis exacerbates alcohol-induced liver injury in mice.
Design and use of peptide-based antibodies decreasing superoxide production by mitochondrial complex I and complex II.
Tags: *Electron Transport Complex I/antagonists & inhibitors/chemistry/immunology/metabolism, *Electron Transport Complex II/antagonists & inhibitors/chemistry/immunology/metabolism, *Mitochondria, *Mitochondrial Proteins/antagonists & inhibitors/chemistry/immunology/metabolism, *Peptides/chemistry/immunology/metabolism, 2011, Amino Acid Motifs, Animals, Biopolymers, Cattle, Chen Yeong-Renn, Department of Integrative Medical Sciences, Female, Heart/chemistry/immunology/metabolism, Kang Patrick T, Kaumaya Pravin P T, NEOMED College of Medicine, Protein Structure, Rabbits, Tertiary, Yun June
Dewetting based fabrication of fibrous micro-scaffolds as potential injectable cell carriers.
Tags: 2015, Animals, Cell retention, Cells, Chilian William M, Department of Integrative Medical Sciences, Dewetting, Fibrous micro-constructs, Immobilized/metabolism/transplantation, Injectable constructs, Materials science & engineering. C, Materials for biological applications, Myocardial Infarction/metabolism/pathology/*therapy, NEOMED College of Medicine, Newby Bi-Min Zhang, Rats, Song Hokyung, Sprague-Dawley, Stem Cell Transplantation/*methods, Stem Cells/*metabolism, Tissue engineering and regeneration, Tissue Scaffolds/*chemistry, Yin Liya
Diagnosis of 'possible' mitochondrial disease: an existential crisis.
Tags: 2019, Akron Children's Hospital, Bertini Enrico Silvio, Chinnery Patrick F, Christodoulou John, clinical genetics, Cohen Bruce H, Davis Ryan L, Department of Integrative Medical Sciences, Department of Pediatrics, Diagnosis, evidence based practice, Falk Marni J, Fratter Carl, Goldstein Amy, Horvath Rita, Journal of medical genetics, Karaa Amel, Koenig Mary Kay, Mancuso Michaelangelo, McCormack Shana, McCormick Elizabeth M, McFarland Robert, metabolic disorders, NEOMED College of Medicine, Nesbitt Victoria, Parikh Sumit, Rahman Shamima, Schiff Manuel, Steele Hannah, Stockler Silvia, Sue Carolyn, Tarnopolsky Mark, Thorburn David R, Vockley Jerry
Diagnosis of 'possible' mitochondrial disease: an existential crisis.
Tags: 2019, Akron Children's Hospital, Bertini Enrico Silvio, Chinnery Patrick F, Christodoulou John, clinical genetics, Cohen Bruce H, Davis Ryan L, Department of Integrative Medical Sciences, Department of Pediatrics, Diagnosis, evidence based practice, Falk Marni J, Fratter Carl, Goldstein Amy, Horvath Rita, Journal of medical genetics, Karaa Amel, Koenig Mary Kay, Mancuso Michaelangelo, McCormack Shana, McCormick Elizabeth M, McFarland Robert, metabolic disorders, NEOMED College of Medicine, Nesbitt Victoria, Parikh Sumit, Rahman Shamima, Schiff Manuel, Steele Hannah, Stockler Silvia, Sue Carolyn, Tarnopolsky Mark, Thorburn David R, Vockley Jerry
Differences in the integration pattern and episomal forms of human papillomavirus type 16 DNA found within an invasive cervical neoplasm and its metastasis.
Tags: 1992, Carcinoma, DeLucia A, Department of Integrative Medical Sciences, DNA, Electrophoresis, Female, Galehouse D, Gel, Humans, Jenison E, NEOMED College of Medicine, Neoplasm Metastasis, Papillomaviridae/*genetics, Plasmids, Squamous Cell/*microbiology/pathology, Two-Dimensional, Uterine Cervical Neoplasms/*microbiology/pathology, Vaginal Neoplasms/microbiology/pathology/secondary, Viral/analysis, Virology, Virus Integration
Differential protein acetylation assists import of excess SOD2 into mitochondria and mediates SOD2 aggregation associated with cardiac hypertrophy in the murine
Tags: *Cardiac-specific transgenic mouse, *Mitochondria, *Mitochondrial translocation, *Protein acetylation, *Protein aggregation, *SOD2, 2017, Acetylation, Animals, Cardiomegaly/*metabolism, Chen Chwen-Lih, Chen Yeong-Renn, Cytosol/*metabolism, Department of Integrative Medical Sciences, Free radical biology & medicine, Heart/*physiology, Jin Zhicheng, Kang Patrick T, Mice, Mitochondria/*metabolism, NEOMED College of Medicine, Pathological, Post-Translational, Protein Aggregation, Protein Folding, Protein Processing, Protein Transport, Reactive Oxygen Species/metabolism, Sirtuin 3/metabolism, Superoxide Dismutase/genetics/*metabolism, Transgenic, Zhang Liwen
Differential regulation of TRPV1 channels by H2O2: implications for diabetic microvascular dysfunction.
Tags: *Coronary Circulation, *Microcirculation, 2016, Animals, Basic research in cardiology, Bratz Ian N, Capsaicin, Chen Yeong-Renn, Connell Patrick J, Coronary blood flow, Damron Derek S, DelloStritto Daniel J, Department of Integrative Medical Sciences, Diabetic Angiopathies/*metabolism, Dick Gregory M, Fahmy Joseph N, Fancher Ibra S, HEK293 Cells, Humans, Hydrogen peroxide, Hydrogen Peroxide/*metabolism, Inbred C57BL, Kang Patrick T, Klarich Brittany, Knockout, Male, Mice, NEOMED College of Medicine, reactive oxygen species, Thodeti Charles K, TRPV Cation Channels/*metabolism, TRPV1
Disruption of TRPV1-mediated coupling of coronary blood flow to cardiac metabolism in diabetic mice: role of nitric oxide and BK channels.
Tags: 13-dienoic Acid/pharmacology, 15-Hydroxy-11 alpha, 2012, 9 alpha-(epoxymethano)prosta-5, American journal of physiology. Heart and circulatory physiology, Anilides/pharmacology, Animals, Bratz Ian N, Capsaicin/analogs & derivatives/pharmacology, Cinnamates/pharmacology, Coronary Vessels/drug effects/*metabolism/physiopathology, Damron Derek S, DelloStritto Daniel J, Department of Integrative Medical Sciences, Diabetes Mellitus, Diabetic Cardiomyopathies/drug therapy/*metabolism, Enzyme Inhibitors/pharmacology, Guarini Giacinta, Inbred C57BL, Kmetz John G, Large-Conductance Calcium-Activated Potassium Channels/antagonists & inhibitors/*metabolism, Male, Meszaros J Gary, Mice, Microvessels/drug effects/physiopathology, NEOMED College of Medicine, NG-Nitroarginine Methyl Ester/pharmacology, Nitric Oxide/*metabolism, Ohanyan Vahagn A, Peptides/pharmacology, Thodeti Charles K, Thoppil Roslin J, TRPV Cation Channels/agonists/antagonists & inhibitors/biosynthesis/*metabolism, Type 2/drug therapy/*metabolism, Vasoconstrictor Agents/pharmacology, Vasodilation/drug effects
Doxorubicin-induced cardiomyopathy: Prevention and treatment by a coronary specific vasodilator
Tags: 2019, Chilian William, Department of Integrative Medical Sciences, Enrick Molly, Faseb Journal, Gyulkhasyan Tigran, Hakobyan Tatevik, Kolz Christopher L, NEOMED College of Medicine, NEOMED College of Medicine Student, NEOMED Student Publications, Ohanyan Vahagn, Parikh Ankur, Peketi Punita, Shockling Lindsay
Drug Delivery and Nanoformulations for the Cardiovascular System.
Early upregulation of myocardial CXCR4 expression is critical for dimethyloxalylglycine-induced cardiac improvement in acute myocardial infarction.
Tags: 2016, alpha Subunit/metabolism, American journal of physiology. Heart and circulatory physiology, Amino Acids, Animal, Animals, Apoptosis/drug effects, Cardiotonic Agents/*pharmacology, Cell Hypoxia, Cell Line, Chilian William M, CXCR4/deficiency/genetics/*metabolism, Department of Integrative Medical Sciences, Dicarboxylic/*pharmacology, Disease Models, Dong Feng, Enzyme Inhibitors/pharmacology, Forudi Farhad, hypoxia, Hypoxia-Inducible Factor 1, Hypoxia-Inducible Factor-Proline Dioxygenases/antagonists & inhibitors/metabolism, Inbred C57BL, Kiedrowski Matthew, Knockout, Left/*drug effects, Mayorga Mari, Mice, myocardial infarction, Myocardial Infarction/*drug therapy/genetics/metabolism/pathology/physiopathology, Myocardium/*metabolism/pathology, NEOMED College of Medicine, Penn Marc S, Rats, Receptors, Recovery of Function, Shamhart Patricia, Signal Transduction/drug effects, stem cells, Stem Cells/drug effects/metabolism, Stroke Volume/drug effects, Time Factors, Up-Regulation, Ventricular Function, Weber Kristal
Ecotropic Murine Leukemia Virus Infection of Glial Progenitors Interferes with Oligodendrocyte Differentiation: Implications for Neurovirulence.
Tags: 2016, 3T3 Cells, Animals, Cardona Sandra M, Cell Line, Cell Proliferation, Cell Survival, Department of Integrative Medical Sciences, Dunphy Jaclyn M, env/biosynthesis, Female, Gene Products, Journal of virology, Leukemia Virus, Li Ying, Lynch Connor R, Lynch William P, Macklin Wendy B, Male, Mice, Motor Neuron Disease/*virology, Murine/*pathogenicity, NEOMED College of Medicine, Neural Stem Cells/*virology, Neurogenesis/*physiology, Neuroglia/*virology, Oligodendroglia/cytology/virology, Pedraza Carlos E, Retroviridae Infections/*complications, Transgenic
Effect of peak inspiratory pressure on the filtration coefficient in the isolated perfused rat lung.
Tags: 1993, Animals, Biological, Body Fluids/physiology, Capillary Permeability, Department of Integrative Medical Sciences, Evaluation Studies as Topic, In Vitro Techniques, Journal of applied physiology (Bethesda, Md. : 1985), Lung/blood supply/*physiology, Male, Maron M B, Models, NEOMED College of Medicine, Niehaus G D, Omlor G, Perfusion, Positive-Pressure Respiration, Pressure, Rats, Respiration/physiology, Sprague-Dawley
Effects of bile acids and steroid/thyroid hormones on the expression of cholesterol 7 alpha-hydroxylase mRNA and the CYP7 gene in HepG2 cells.
Tags: 1994, Animals, Bile Acids and Salts/*pharmacology, Biochemical and biophysical research communications, Cells, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics, Crestani M, Cultured, Department of Integrative Medical Sciences, Enzymologic/*drug effects, Gene Expression Regulation, Genetic, Genetic/genetics, Humans, Karam W G, Luciferases/biosynthesis/genetics, Messenger/*biosynthesis, NEOMED College of Medicine, Promoter Regions, Rats, Recombinant Fusion Proteins/biosynthesis, RNA, Steroids/*pharmacology, Thyroid Hormones/*pharmacology, Transcription, Transfection
Eicosanoids in metabolic syndrome.
Tags: 2013, Abdelmegeed Mohamed A, Adipose Tissue, Advances in pharmacology (San Diego, Calif.), Animals, Chiang John Y, Chilian William M, Department of Integrative Medical Sciences, Eckman Katie, Eicosanoids/*metabolism, Esterle Andrew, Fatty Liver/etiology/immunology/metabolism, Hardwick James P, Humans, Immune System/immunology/metabolism, Lee Yoon-Kwang, Lipid Metabolism, Metabolic Syndrome/complications/immunology/*metabolism/physiopathology, NEOMED College of Medicine, Non-alcoholic Fatty Liver Disease, Obesity/complications/immunology/metabolism, Sepsis/complications/immunology/metabolism, Song Byoung-Joon, White/immunology/metabolism
Endothelial TRPV4 channels prevent tumor growth and metastasis via modulation of tumor angiogenesis and vascular integrity.
Tags: 2021, Adapala RK, angiogenesis, Department of Integrative Medical Sciences, endothelial cell, Guarino BD, Jamaiyar A, journalArticle, Kanugula AK, Lenkey N, Liedtke W, March 2021 List, Metastasis, NEOMED College of Medicine, NEOMED Postdoc Publications, NEOMED Student Publications, Paruchuri S, Thodeti CK, Transient receptor potential vanilloid 4, tumor angiogenesis, Vascular endothelial growth factor receptor 2, Yin L
Endothelial Trpv4 contributes to pressure overload-induced pathological hypertrophy via modulation of coronary angiogenesis
Tags: 2020, Adapala RK, angiogenesis, Cardiac hypertrophy, Chilian WM, Circulation research, Department of Integrative Medical Sciences, Fibrosis, Ion Channels, January 2021 List, journalArticle, Kanugula AK, NEOMED College of Graduate Studies, NEOMED College of Medicine, NEOMED Student Publications, Ohanyan VA, Paruchuri SM, Thodeti CK
Endothelin-mediated in vivo pressor responses following TRPV1 activation.
Tags: *Blood Pressure/drug effects, *Vasoconstriction/drug effects, 2011, Adrenergic alpha-Agonists/administration & dosage, American journal of physiology. Heart and circulatory physiology, Analysis of Variance, Animal, Animals, Azepines/administration & dosage, Biphenyl Compounds/administration & dosage, Bratz Ian N, Capsaicin/administration & dosage, Cells, Cultured, Damron Derek S, Department of Integrative Medical Sciences, Diabetes Mellitus, Diabetic Angiopathies/genetics/*metabolism/physiopathology, Dipeptides/administration & dosage, Disease Models, Dose-Response Relationship, Drug, Endothelial Cells/metabolism, Endothelin A Receptor Antagonists, Endothelin A/metabolism, Endothelin B Receptor Antagonists, Endothelin B/metabolism, Endothelin-1/*metabolism, Enzyme-Linked Immunosorbent Assay, Femoral Artery/drug effects/*metabolism/physiopathology, Guarini Giacinta, Haney Rebecca M, Inbred C57BL, Indoles/administration & dosage, Infusions, Intravenous, Knockout, Male, Meszaros J Gary, Mice, NEOMED College of Medicine, Ohanyan Vahagn A, Phenylephrine/administration & dosage, Raman Priya, Receptor, Talasila Phani K, Thodeti Charles K, TRPV Cation Channels/agonists/deficiency/genetics/*metabolism, Type 2/genetics/*metabolism/physiopathology, Vasoconstrictor Agents/administration & dosage
Enhanced ethanol catabolism in orphan nuclear receptor SHP-null mice.
Tags: *acetaldehyde dehydrogenase, *alcoholic fatty liver disease, *Inflammation, *small heterodimer partner, 2016, Acetates/blood, Alcoholic/genetics/*metabolism, Aldehyde Dehydrogenase, American journal of physiology. Gastrointestinal and liver physiology, Animals, Cytoplasmic and Nuclear/deficiency/*genetics/metabolism, Department of Integrative Medical Sciences, Ethanol/blood/*metabolism/toxicity, Inbred C57BL, Lee Mikang, Lee Yoon-Kwang, Lipid Peroxidation, Liver Diseases, Liver/drug effects/metabolism, Male, Mice, Mifflin Ryan, Mitochondrial/genetics/metabolism, NEOMED College of Medicine, Park Jung Eun, PPAR gamma/genetics/metabolism, Receptors
Estrogen-related receptor gamma controls hepatic CB1 receptor-mediated CYP2E1 expression and oxidative liver injury by alcohol.
Tags: 2013, Alcohol-Induced Injury, Alcoholic Liver Disease, Alcoholic/genetics/*metabolism/prevention & control, Animals, Cannabinoid, CB1/*physiology, Chiang John Y L, Choi Hueng-Sik, Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 CYP2E1/genetics/*metabolism, Department of Integrative Medical Sciences, Enzyme Inhibitors/pharmacology/therapeutic use, Enzymologic/drug effects/physiology, Estrogen/deficiency/genetics/*physiology, Ethanol/pharmacology, Gene Expression Profiling/methods, Gene Expression Regulation, Gene Regulation, Genetic/physiology, Gut, Inbred C57BL, Jang Hyun-Hee, Jeong Won-Il, Kim Don-Kyu, Kim Jung Ran, Kim Yong-Hoon, Knockout, Koh Minseob, Koo Seung-Hoi, Lee Chul-Ho, Liver, Liver Diseases, Liver Metabolism, Liver/metabolism, Male, Mice, NEOMED College of Medicine, Oxidation-Reduction, Oxidative Stress/physiology, Park Jinyoung, Park Seung Bum, Park Tae-Sik, Receptor, Receptors, Signal Transduction/drug effects/physiology, Tamoxifen/analogs & derivatives/pharmacology/therapeutic use, Transcription, Yun Chul-Ho
Exosomal microRNAs in the development of essential hypertension and its potential as biomarkers.
Tags: 2021, American journal of physiology. Heart and circulatory physiology, Chia YC, Chilian WM, Ching SM, clinical biomarker, Department of Integrative Medical Sciences, extracellular vesicles, Hall D, high blood pressure, journalArticle, Kumar DN, Lim HM, Low TY, March 2021 List, microvesicles, Mohd ZS, NEOMED College of Medicine, Noh MFM, Pung Y-F, small non-coding RNA, Tan PPS
Exosomes derived from Induced Vascular Progenitor Cells Promote Angiogenesis in vitro and in an in vivo Rat Hindlimb Ischemia Model
Tags: 2019, American journal of physiology. Heart and circulatory physiology, angiogenesis, Chilian William M, Department of Integrative Medical Sciences, endothelial cell, exosome, Johnson Takerra K, Kirlin Ward G, Liu Dong, MicroRNA, NEOMED College of Medicine, Oguljahan Babayewa, progenitor cell, September 2019 Update, Wang Yang, Xiao Yan, Yin Liya, Zhao Lina, Zhao Xueying, Zhu Dihan
Experimental animal models of coronary microvascular dysfunction.
Exploring Adenosine Receptor Ligands: Potential Role in the Treatment of Cardiovascular Diseases.
Tags: *drug discovery, *Ligands, 2017, Adenosine/metabolism, Animals, Atherosclerosis, Cardiac death, Cardiovascular Diseases/drug therapy/metabolism, Cardiovascular System/metabolism, Department of Integrative Medical Sciences, Geldenhuys Werner J, Hanif Ahmad, Humans, Hydrogen Bonding, Models, Molecular, Molecular Structure, Molecules (Basel, Switzerland), myocardial infarction, Nayeem Mohammed A, NEOMED College of Medicine, Protein Binding, Purinergic P1/*chemistry/*metabolism, Receptors, Signal Transduction, Structure-Activity Relationship, Vascular tone, Yun June
Expression and purification of human cholesterol 7 alpha-hydroxylase in Escherichia coli.
Tags: 1994, Animals, Base Sequence, Catalysis, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/biosynthesis/genetics/*isolation & purification, Cytochrome P-450 Enzyme System/biosynthesis/isolation & purification, Department of Integrative Medical Sciences, Escherichia coli, Humans, Immunochemistry, Journal of lipid research, Karam W G, Kinetics, Molecular Sequence Data, NEOMED College of Medicine, Rats, Recombinant Proteins/biosynthesis, Solubility, Subcellular Fractions/enzymology
Expression of hepatic microsomal cholesterol 7 alpha-hydroxylase activity in lean and obese Zucker rats.
Tags: 1988, Animals, Biochemical and biophysical research communications, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*metabolism, Cholestyramine Resin/pharmacology, Department of Integrative Medical Sciences, Female, Finkelstein J A, Liver/*enzymology, Male, Microsomes, NEOMED College of Medicine, Obesity/*metabolism, Rats, Sex Factors, Species Specificity, Steroid Hydroxylases/*metabolism, Tang P M, Zucker/metabolism