Browse Items (87 total)
- Tags: Cultured
A novel role of transforming growth factor beta1 in transcriptional repression of human cholesterol 7alpha-hydroxylase gene.
Tags: 2007, Bile Acids and Salts/metabolism, Carcinoma, Cell Line, Cells, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*genetics/*metabolism, Cultured, Department of Integrative Medical Sciences, Enzyme Inhibitors/pharmacology, Gastroenterology, Genetic/drug effects/*physiology, Hepatocellular/*metabolism/pathology, Hepatocyte Nuclear Factor 4/metabolism, Hepatocytes/drug effects/*metabolism/pathology, Humans, Hydroxamic Acids/pharmacology, Li Tiangang, Liver Neoplasms/*metabolism/pathology, Messenger/metabolism, NEOMED College of Medicine, RNA, Signal Transduction/physiology, Smad3 Protein/metabolism, Transcription, Transforming Growth Factor beta1/*metabolism, Tumor
A wogonin-rich-fraction of Scutellaria baicalensis root extract exerts chondroprotective effects by suppressing IL-1beta-induced activation of AP-1 in human OA chondrocytes.
Tags: 2017, Ansari Mohammad Y, Cells, Chemical Fractionation/methods, Chondrocytes/*drug effects/metabolism, Cultured, Cyclooxygenase 2/genetics/metabolism, Department of Anatomy & Neurobiology, Flavanones/*pharmacology, Gene Expression Regulation/drug effects, Haqqi Tariq M, Haseeb Abdul, Humans, Interleukin-1beta/pharmacology, Interleukin-6/genetics/metabolism, Khan Nazir M, NEOMED College of Medicine, Osteoarthritis/pathology, Plant Extracts/*pharmacology, Plant Roots/*chemistry, Protective Agents/pharmacology, Reactive Oxygen Species/metabolism, Scientific reports, Scutellaria baicalensis/*chemistry, Transcription Factor AP-1/genetics/*metabolism
Tags: 2004, Aging/*metabolism, Animals, Articular/cytology/*metabolism, Carrier Proteins/genetics/*metabolism, Cartilage, Cell Division/physiology, Cells, Chondrocytes/cytology/*metabolism, Cultured, Department of Anatomy & Neurobiology, DNA-Binding Proteins, Gene Expression Regulation, Growth Plate/*metabolism, Horton Walter E Jr, Inbred C57BL, Kinkel Mary D, McBurney Denise, Mice, NEOMED College of Medicine, Nugent Ashleigh, Proto-Oncogene Proteins c-bcl-2/*metabolism, The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology, Tissue Distribution, Transcription Factors, Yagi Rieko
Alignment of inducible vascular progenitor cells on a micro-bundle scaffold improves cardiac repair following myocardial infarction.
Tags: *Cardiovascular regeneration, *Ischemic heart diseases, *Micro-bundle scaffold, *Myocardial infarction, *Neovascularization, *Stem cells, *Tissue Scaffolds, *Vascular progenitor cells, 2017, Animal, Animals, Basic research in cardiology, Cell Differentiation, Cell Proliferation, Cell Survival, Cells, Chilian William M, Coculture Techniques, Cultured, Cumpston Devan, Department of Integrative Medical Sciences, Disease Models, Dong Feng, Endothelial Progenitor Cells/metabolism/*transplantation, Enrick Molly, Fibroblast Growth Factor 2/metabolism, Hakobyan Tatev, Jamaiyar Anurag, Janota Danielle, Kolz Christopher L, Lactic Acid/*chemistry, Muscle, Myocardial Infarction/metabolism/pathology/physiopathology/*surgery, Myocardium/metabolism/*pathology, Myocytes, NEOMED College of Medicine, Newby Bi-Min Zhang, Ohanyan Vahagn, Paracrine Communication, Phenotype, Physiologic, Polyglycolic Acid/*chemistry, Polylactic Acid-Polyglycolic Acid Copolymer, Rats, Signal Transduction, Smooth, Smooth Muscle/metabolism/*transplantation, Song Hokyung, Sprague-Dawley, Stevanov Kelly, Time Factors, Tissue Engineering/*methods, Vascular Endothelial Growth Factor A/metabolism, Vascular/metabolism/*transplantation, Ventricular Remodeling, Wan Weiguo, Yin Liya
Tags: *CHONDROCYTES, *OSTEOARTHRITIS, *siRNA, *Transfection, 2017, Aggrecans/genetics, Akhtar Nahid, Analytical biochemistry, Articular/metabolism/pathology, Cartilage, Cells, Chondrocytes/cytology/*metabolism, Collagen Type II/genetics, Cultured, Department of Anatomy & Neurobiology, Haqqi Tariq M, Humans, Makki Mohammad Shahidul, Messenger/*genetics, mRNA Cleavage and Polyadenylation Factors/antagonists & inhibitors/genetics, NEOMED College of Medicine, Nucleotidyltransferases/antagonists & inhibitors/genetics, Plasmids/*genetics, RNA, Small Interfering/*genetics, Transfection/*methods
Angiotensin II-induced extracellular signal-regulated kinase 1/2 activation is mediated by protein kinase Cdelta and intracellular calcium in adult rat cardiac fibroblasts.
Tags: 2008, Acetophenones/pharmacology, Angiotensin II/*physiology, Animals, Benzopyrans/pharmacology, Calcium/*metabolism, Cell Proliferation, Cells, Cultured, Department of Integrative Medical Sciences, Enzyme Activation, ErbB Receptors/metabolism, Fibroblasts/*metabolism, Hypertension (Dallas, Tex. : 1979), Male, Meszaros J Gary, Mitogen-Activated Protein Kinase 1/*metabolism, Mitogen-Activated Protein Kinase 3/*metabolism, Myocardium/*cytology/metabolism, Naugle Jennifer E, NEOMED College of Medicine, Olson Erik R, Phorbol Esters/pharmacology, Phosphorylation, Protein Kinase C-delta/genetics/*metabolism, Rats, Shamhart Patricia E, Signal Transduction/physiology, Sprague-Dawley
Anti-atherogenic effect of trivalent chromium-loaded CPMV nanoparticles in human aortic smooth muscle cells under hyperglycemic conditions in vitro.
Tags: *Comovirus, 2016, Aorta/*metabolism, Atherosclerosis/*drug therapy/therapy, Azo Compounds/chemistry, Cell Proliferation, Cells, Chlorides/*chemistry, Chromium Compounds/*chemistry, Cultured, Cytokines/metabolism, Czech Tori, Department of Integrative Medical Sciences, Drug Delivery Systems, Electron, Fluorescence, Ganguly Rituparna, Glucose/chemistry, Humans, Hyperglycemia/*metabolism, Lipids/chemistry, Microscopy, Myer Ashley B, Myocytes, Nanoparticles/chemistry, Nanoscale, NEOMED College of Medicine, NF-kappa B/metabolism, Proliferating Cell Nuclear Antigen/chemistry, Raman Priya, Sahu Soumyadip, Smooth Muscle/*metabolism, Spectrophotometry, Steinmetz Nicole F, Transforming Growth Factor beta/metabolism, Transmission, Ultraviolet, Wen Amy M
Basic transcription element binding protein (BTEB) transactivates the cholesterol 7 alpha-hydroxylase gene (CYP7A).
Tags: *Gene Expression Regulation, 1998, Animals, Bile Acids and Salts/genetics, Binding Sites/genetics, Biochemical and biophysical research communications, Carcinoma, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics/metabolism, Complementary/analysis, Cultured, Department of Integrative Medical Sciences, DNA, DNA-Binding Proteins/metabolism/*physiology, Electrophoresis, Enzyme Activation/genetics, Foti D, Genetic, Hepatocellular, Humans, Kruppel-Like Transcription Factors, Liver/enzymology, NEOMED College of Medicine, Podophyllin/analogs & derivatives/metabolism, Podophyllotoxin/analogs & derivatives, Polyacrylamide Gel, Promoter Regions, Protein Binding/genetics, Rats, Stroup D, Transcription Factors/metabolism/*physiology, Tumor Cells
Bile acids and cytokines inhibit the human cholesterol 7 alpha-hydroxylase gene via the JNK/c-jun pathway in human liver cells.
Tags: 2006, Bile Acids and Salts/*metabolism, Cells, Chenodeoxycholic Acid/pharmacology, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*genetics/metabolism, Cultured, Cytokines/*metabolism, Department of Integrative Medical Sciences, Gene Expression Regulation, Genetic, Hepatocytes/*cytology/drug effects, Hepatology (Baltimore, Md.), Humans, Immunoblotting, In Vitro Techniques, Interleukin-1/pharmacology, Jahan Asmeen, Li Tiangang, Messenger/analysis, NEOMED College of Medicine, Probability, Proto-Oncogene Proteins c-jun/*metabolism, Reverse Transcriptase Polymerase Chain Reaction, RNA, Sensitivity and Specificity, Signal Transduction/genetics, Transcription
Butein Activates Autophagy Through AMPK/TSC2/ULK1/mTOR Pathway to Inhibit IL-6 Expression in IL-1beta Stimulated Human Chondrocytes.
Tags: 2018, Ahmad Nashrah, AMP-Activated Protein Kinases/metabolism, AMPK, Ansari Mohammad Y, Articular/cytology/pathology, Autophagy, Autophagy-Related Protein 5/antagonists & inhibitors/genetics/metabolism, Autophagy-Related Protein-1 Homolog/metabolism, Autophagy/*drug effects, Butein, Cartilage, Cell Survival/drug effects, Cells, Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Chalcones/*pharmacology, Chondrocytes/cytology/drug effects/metabolism, Cultured, Department of Anatomy & Neurobiology, Haqqi Tariq M, Humans, Inflammation, Interleukin-1beta/*pharmacology, Interleukin-6/genetics/*metabolism, Intracellular Signaling Peptides and Proteins/metabolism, mTOR, NEOMED College of Medicine, Osteoarthritis, Osteoarthritis/metabolism/pathology, Phosphorylation/drug effects, Reactive Oxygen Species/metabolism, RNA, RNA Interference, Signal Transduction/*drug effects, Small Interfering/metabolism, TOR Serine-Threonine Kinases/metabolism, TSC2, Tuberous Sclerosis Complex 2 Protein, Tumor Suppressor Proteins/metabolism, ULK1
Cell cycle arrest and autoschizis in a human bladder carcinoma cell line following Vitamin C and Vitamin K3 treatment.
Tags: 2004, Antioxidants/*pharmacology, Ascorbic Acid/*pharmacology, Biochemical pharmacology, Calcium/metabolism, Cell Cycle/*drug effects, Cultured, DNA, Flow Cytometry, Gilloteaux Jacques, Humans, Hydrogen Peroxide/metabolism, Jamison James M, Male, Nassiri M Reza, Neal Deborah R, Neoplasm/drug effects, Sulfhydryl Compounds/metabolism, Summers Jack L, Tumor Cells, Urinary Bladder Neoplasms/pathology, Venugopal Meenakshi, Vitamin K 3/*pharmacology
Tags: *adult stem cells, *Biomedical Research, *Cell Dedifferentiation, *culture purity, *dedifferentiated fat cells, *dedifferentiation, *surface marker, 2016, Adipocytes/*cytology, Animals, Cells, Cultured, Evancho-Chapman M Michelle, George Richard L, Humans, Organogenesis, Phenotype, Shah Mickey, Zhang Ge
Effects of bile acids and steroid/thyroid hormones on the expression of cholesterol 7 alpha-hydroxylase mRNA and the CYP7 gene in HepG2 cells.
Tags: 1994, Animals, Bile Acids and Salts/*pharmacology, Biochemical and biophysical research communications, Cells, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics, Crestani M, Cultured, Department of Integrative Medical Sciences, Enzymologic/*drug effects, Gene Expression Regulation, Genetic, Genetic/genetics, Humans, Karam W G, Luciferases/biosynthesis/genetics, Messenger/*biosynthesis, NEOMED College of Medicine, Promoter Regions, Rats, Recombinant Fusion Proteins/biosynthesis, RNA, Steroids/*pharmacology, Thyroid Hormones/*pharmacology, Transcription, Transfection
Effects of FGF-2 and OP-1 in vitro on donor source cartilage for auricular reconstruction tissue engineering.
Tags: 2014, Bone Morphogenetic Protein 7/*pharmacology, Cell Differentiation/drug effects, Cells, Child, Chondrocytes, Chondrocytes/*drug effects/physiology, Congenital Abnormalities/diagnosis/*surgery, Congenital Microtia, Cultured, Ear Cartilage/surgery, Ear/*abnormalities/surgery, FGF-2, Fibroblast Growth Factor 2/*pharmacology, Humans, International journal of pediatric otorhinolaryngology, Isogai Noritaka, Jacquet Robin, Landis William J, Male, Matsushima Seika, McClellan Phillip, Microtia, Murthy Ananth, OP-1, Reconstructive Surgical Procedures/*methods, Reference Values, Shasti Mark, Tissue Donors, Tissue Engineering, Tissue Engineering/*methods, Yang Julianne
Tags: *Blood Pressure/drug effects, *Vasoconstriction/drug effects, 2011, Adrenergic alpha-Agonists/administration & dosage, American journal of physiology. Heart and circulatory physiology, Analysis of Variance, Animal, Animals, Azepines/administration & dosage, Biphenyl Compounds/administration & dosage, Bratz Ian N, Capsaicin/administration & dosage, Cells, Cultured, Damron Derek S, Department of Integrative Medical Sciences, Diabetes Mellitus, Diabetic Angiopathies/genetics/*metabolism/physiopathology, Dipeptides/administration & dosage, Disease Models, Dose-Response Relationship, Drug, Endothelial Cells/metabolism, Endothelin A Receptor Antagonists, Endothelin A/metabolism, Endothelin B Receptor Antagonists, Endothelin B/metabolism, Endothelin-1/*metabolism, Enzyme-Linked Immunosorbent Assay, Femoral Artery/drug effects/*metabolism/physiopathology, Guarini Giacinta, Haney Rebecca M, Inbred C57BL, Indoles/administration & dosage, Infusions, Intravenous, Knockout, Male, Meszaros J Gary, Mice, NEOMED College of Medicine, Ohanyan Vahagn A, Phenylephrine/administration & dosage, Raman Priya, Receptor, Talasila Phani K, Thodeti Charles K, TRPV Cation Channels/agonists/deficiency/genetics/*metabolism, Type 2/genetics/*metabolism/physiopathology, Vasoconstrictor Agents/administration & dosage
Enhanced antiviral activity and altered subcellular distribution of magnesium/poly r(A-U) combinations.
Tags: 1992, Antiviral Agents/*pharmacology, Cell biology international reports, Cells, Chromatin/drug effects, Cultured, Ethidium/*pharmacology, Gilloteaux J, Humans, Jamison J M, Krabill K, Magnesium/metabolism/*pharmacology, Nucleolus Organizer Region/*drug effects, Poly A-U/*pharmacology, Summers J L, Vesicular stomatitis Indiana virus/drug effects
Experimental use of fibrin glue to induce site-directed osteogenesis from cultured periosteal cells.
Tags: *Fibrin Tissue Adhesive, *Osteogenesis, 2000, Animals, Bone and Bones/chemistry/cytology/diagnostic imaging, Cattle, Cells, Cultured, Experimental, Gerstenfeld L C, Gotoh Y, Implants, Injections, Isogai N, Landis W J, Mice, Mori R, Non-programmatic, Nude, Osteopontin, Periosteum/*cytology, Plastic and reconstructive surgery, Radiography, Sialoglycoproteins/analysis, Upton J, Vacanti J P
Farnesoid X receptor responds to bile acids and represses cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription.
Tags: *Transcription, 2000, Animals, Bile Acids and Salts/*pharmacology, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics, Cricetinae, Cultured, Cytoplasmic and Nuclear, Department of Integrative Medical Sciences, DNA-Binding Proteins/*physiology, Genetic, Humans, Kimmel R, NEOMED College of Medicine, Promoter Regions, Receptors, Repressor Proteins/*physiology, Response Elements, Retinoic Acid/genetics, Retinoid X Receptors, Stroup D, The Journal of biological chemistry, Transcription Factors/genetics/*physiology, Tumor Cells, Weinberger C
Tags: *Mesenchymal Stem Cell Transplantation, *Regeneration, 2014, Anal Canal/injuries/metabolism/pathology/physiopathology/*surgery, Anal pressures, Anal sphincter, Animal, Animals, Balog Brian, Cells, Cultured, Damaser Margot, Disease Models, Fecal incontinence, Female, Fibrosis, Green Fluorescent Proteins/biosynthesis/genetics, i.v. infusion, Infusions, Injections, Intralesional, Intravenous, Mesenchymal stem cells, Mesenchymal Stem Cells/metabolism, Penn Marc, Pressure, Rats, Recovery of Function, Salcedo Levilester, Sprague-Dawley, Stem cells translational medicine, Time Factors, Transfection, Zutshi Massarat
Glucagon and cAMP inhibit cholesterol 7alpha-hydroxylase (CYP7A1) gene expression in human hepatocytes: discordant regulation of bile acid synthesis and gluconeogenesis.
Tags: *Gluconeogenesis, 2006, 8-Bromo Cyclic Adenosine Monophosphate/*pharmacology, Adolescent, Bile Acids and Salts/*biosynthesis, Cells, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*genetics, Chromatin/metabolism, Cultured, Cyclic AMP-Dependent Protein Kinases/physiology, Department of Integrative Medical Sciences, Enzymologic/*drug effects, Female, Gene Expression Regulation, Genetic/drug effects, Glucagon/*pharmacology, Hepatocyte Nuclear Factor 4/genetics/metabolism, Hepatocytes/*enzymology, Hepatology (Baltimore, Md.), Humans, Male, Messenger/analysis, Middle Aged, NEOMED College of Medicine, Organ Specificity, Phosphorylation, RNA, Song Kwang-Hoon, Transcription
Tags: *Gene Expression Regulation, 2010, Acetylation, AMP-Activated Protein Kinases/metabolism, ATP Citrate (pro-S)-Lyase/genetics/metabolism, Bile Acids and Salts/metabolism, Cells, Chanda Dipanjan, Chiang John Y L, Choi Hueng-Sik, Cholesterol 7-alpha-Hydroxylase/genetics/*metabolism, Cultured, Department of Integrative Medical Sciences, DNA-Binding Proteins/metabolism, Enzymologic, Epigenesis, Genes, Genetic, Glucose/*administration & dosage, Hep G2 Cells, Hepatocyte Nuclear Factor 4/metabolism, Hepatocytes/*enzymology/metabolism, Histones/metabolism, Humans, Hyperglycemia/enzymology/*metabolism, Journal of lipid research, Li Tiangang, Messenger/metabolism, Methylation, NEOMED College of Medicine, Reporter, RNA, RNA Interference, Zhang Yanqiao
Glycation Reduces the Stability of ApoAI and Increases HDL Dysfunction in Diet-Controlled Type 2 Diabetes.
Tags: 2018, Adult, Aged, Animal Studies, Animals, Apolipoprotein A-I/blood/*metabolism, Apolipoproteins – Blood, Apolipoproteins – Metabolism, Bena James, Biochemical Phenomena, Case Control Studies, Case-Control Studies, Cells, Comparative Studies, Cultured, Department of Pharmaceutical Sciences, Diabetes Mellitus, Diet, Dyslipidemias/complications/diet therapy/*metabolism, Evaluation Research, Female, Funding Source, Glycosylation, Golizeh Makan, HDL – Metabolism, HDL/*metabolism, Human, Humans, Hyperglycemia – Complications, Hyperglycemia – Diet Therapy, Hyperglycemia – Metabolism, Hyperglycemia/complications/diet therapy/*metabolism, Hyperlipidemia – Complications, Hyperlipidemia – Diet Therapy, Hyperlipidemia – Metabolism, Ilchenko Serguei, Kashyap Sangeeta R, Kasumov Takhar, Lee Kwangwon, Lipoproteins, Male, Mice, Middle Age, Middle Aged, Multicenter Studies, NEOMED College of Pharmacy, Osme Abdullah, Previs Stephen F, Protein Stability, Smith Jonathan D, The Journal of clinical endocrinology and metabolism, Type 2 – Complications, Type 2 – Diet Therapy, Type 2 – Metabolism, Type 2/complications/*diet therapy/metabolism, Validation Studies, Wang Shuhui
Glycoprotein Nonmelanoma Clone B Regulates the Crosstalk between Macrophages and Mesenchymal Stem Cells toward Wound Repair.
Tags: 2018, Administration, Alboslemy Talib, Animal, Animals, Cell Communication/*physiology, Cell Differentiation, Cells, Cultured, Cutaneous, Diabetes Mellitus, Disease Models, Eye Proteins/administration & dosage/genetics/*physiology, Humans, Inbred C57BL, Kim Min-Ho, Macrophages/*physiology, Male, Membrane Glycoproteins/administration & dosage/genetics/*physiology, Mesenchymal Stem Cells/*physiology, Mice, Recombinant Proteins/administration & dosage/genetics/metabolism, Safadi Fayez, Skin/*injuries/metabolism, The Journal of investigative dermatology, Type 2/complications/pathology, Wound Healing/*physiology, Yu Bing
Hepatic hepatocyte nuclear factor 4alpha is essential for maintaining triglyceride and cholesterol homeostasis.
Tags: 2011, Adenoviridae/genetics, Animal, Animals, Arteriosclerosis, thrombosis, and vascular biology, Cells, Cholesterol, Cholesterol/*metabolism, Cultured, Department of Integrative Medical Sciences, Edwards Peter A, Fatty Liver/metabolism/physiopathology, Ge Xuemei, HDL/metabolism, Hepatocyte Nuclear Factor 4/drug effects/genetics/*physiology, Hepatocytes/cytology/*metabolism, Homeostasis/genetics/*physiology, Inbred C57BL, Lipid Metabolism/genetics/physiology, Ma Huiyan, Mice, Models, NEOMED College of Medicine, RNA, Small Interfering/genetics/pharmacology, Triglycerides/*metabolism, VLDL/metabolism, Yin Liya, Zhang Yanqiao
Hepatocyte growth factor signaling pathway inhibits cholesterol 7alpha-hydroxylase and bile acid synthesis in human hepatocytes.
Tags: 2007, Bile Acids and Salts/*biosynthesis, Cells, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*biosynthesis, Cultured, Department of Integrative Medical Sciences, Ellis Ewa, Hepatocyte Growth Factor/*metabolism, Hepatocytes/*metabolism, Hepatology (Baltimore, Md.), Humans, NEOMED College of Medicine, Signal Transduction, Song Kwang-Hoon, Strom Stephen
Tags: *Tissue Scaffolds, 2009, Animals, Cell Differentiation/physiology, Cell Proliferation, Cell Shape/physiology, Cells, Chondrocytes/*cytology/*metabolism/transplantation, Chondrogenesis/physiology, Collagen/metabolism, Connective tissue research, Cultured, Doherty Alison, Fibrocartilage/cytology/metabolism/transplantation, Graft Survival/physiology, Heterologous/methods, Histocytochemistry, Humans, Jacquet Robin, Landis William J, Leeson Mark C, Lowder Elizabeth, Male, Menisci, Mice, Middle Aged, Nude, Phenotype, Polyglycolic Acid/pharmacology/therapeutic use, Schoenfeld Andrew J, Tibial/*cytology/*metabolism/transplantation, Tissue Engineering/*methods, Transplantation
Histone deacetylase inhibitor vorinostat (SAHA, MK0683) perturb miR-9-MCPIP1 axis to block IL-1beta-induced IL-6 expression in human OA chondrocytes.
Tags: *IL-6, *MCPIP1, *miRNA, *OSTEOARTHRITIS, *Vorinostat, 2017, Adult, Aged, CCAAT-Enhancer-Binding Proteins/genetics/metabolism, Cells, Chondrocytes/*metabolism/pathology, Connective tissue research, Cultured, Department of Anatomy & Neurobiology, Female, Gene Expression Regulation/*drug effects, Genetic, Haqqi Tariq M, Humans, Hydroxamic Acids/*pharmacology, Interleukin-1beta/genetics/*metabolism, Interleukin-6/genetics/*metabolism, Makki Mohammad S, Male, MicroRNAs/genetics/*metabolism, Middle Aged, NEOMED College of Medicine, Osteoarthritis/drug therapy/genetics/*metabolism/pathology, Promoter Regions, Ribonucleases/*biosynthesis/genetics, Transcription Factors/*biosynthesis/genetics, Vorinostat
HNF4 and COUP-TFII interact to modulate transcription of the cholesterol 7alpha-hydroxylase gene (CYP7A1).
Tags: *Receptors, *Transcription, 2000, Animals, Base Sequence, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics, COUP Transcription Factor II, COUP Transcription Factors, Cultured, Department of Integrative Medical Sciences, DNA Primers, DNA-Binding Proteins/*metabolism, Genes, Genetic, Hepatocyte Nuclear Factor 4, Humans, Journal of lipid research, Liver/metabolism, Luciferases/genetics, Mutation, NEOMED College of Medicine, Phosphoproteins/*metabolism, Promoter Regions, Rats, Recombinant Proteins/metabolism, Reporter, Sprague-Dawley, Steroid, Stroup D, Transcription Factors/*metabolism, Tumor Cells
Tags: *Promoter Regions, *Transcription, 1995, Animals, Base Sequence, Cell Count, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics, Cloning, Crestani M, Cultured, Cyclic AMP/pharmacology, Department of Integrative Medical Sciences, Enzymologic/*physiology, Gene Expression Regulation, Genetic, Hormones/*pharmacology, Journal of lipid research, Luciferases/genetics, Molecular, Molecular Sequence Data, NEOMED College of Medicine, Phorbol Esters/pharmacology, Rats, Second Messenger Systems/physiology, Stroup D, Transfection, Tumor Cells
Tags: *Cell Differentiation, 2014, Adapala Ravi K, Animals, Blood Glucose/metabolism, Bryant Jennifer E, Canadian journal of physiology and pharmacology, cardiac fibroblast, Cell Movement, Cell Proliferation, Cells, Collagen, Collagen/metabolism, collagene, concentration elevee de glucose, Cultured, Department of Integrative Medical Sciences, diabete, Diabetes, fibroblaste cardiaque, Fibroblasts/*metabolism/pathology, Fibrosis, high glucose, Hyperglycemia/*metabolism/pathology, Luther Daniel J, Male, Meszaros J Gary, migration, Myocardium/*metabolism/pathology, myofibroblast, myofibroblastes, NEOMED College of Medicine, Petersen Kyle A, proliferation, Rats, Shamhart Patricia E, Signal Transduction, Sprague-Dawley, Thodeti Charles K
Tags: 1997, Animals, Base Sequence, Bile Acids and Salts/*pharmacology, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics, Crestani M, Cultured, Department of Integrative Medical Sciences, DNA-Binding Proteins/metabolism, Feedback, Genes, Genes/*drug effects, Luciferases/genetics, NEOMED College of Medicine, Rats, Reporter, Stroup D, The American journal of physiology, Tumor Cells
Tags: 1996, Anti-Infective Agents, Articular/immunology/physiology/*transplantation, Biomechanical Phenomena, Bone Transplantation/*immunology, Cells, Clinical orthopaedics and related research, Cultured, Ethanol/pharmacology, Fibroblasts/drug effects, Homologous, Humans, Hydrogen Peroxide/pharmacology, Ligaments, Local/pharmacology, Pinkowski J L, Povidone-Iodine/pharmacology, Rodrigo J J, Sharkey N A, Therapeutic Irrigation, Tissue Preservation, Transplantation, Vasseur P B
Induction of vascular progenitor cells from endothelial cells stimulates coronary collateral growth.
Tags: *Collateral Circulation, *Coronary Circulation, 2012, Animal, Animals, Bailey Erin, Biomarkers/metabolism, Cell Differentiation, Cell Lineage, Cells, Chilian William M, Circulation research, Coronary Occlusion/genetics/metabolism/pathology/physiopathology/*surgery, Coronary Vessels/metabolism/pathology/*physiopathology, Cultured, Delucia Angelo, Department of Integrative Medical Sciences, Developmental, Disease Models, Endothelial Cells/metabolism/pathology/*transplantation, Enrick Molly, Epigenesis, Gene Expression Profiling, Gene Expression Regulation, Genetic, Guarini Giacinta, Induced Pluripotent Stem Cells/metabolism/*transplantation, Kolz Christopher L, Mice, Muscle, Myocytes, NEOMED College of Medicine, Neovascularization, Ohanyan Vahagn, Physiologic, Pung Yuh Fen, Rats, Regenerative Medicine/methods, Regional Blood Flow, Reverse Transcriptase Polymerase Chain Reaction, SCID, Smooth, Smooth Muscle/metabolism/pathology/*transplantation, Sprague-Dawley, Stevanov Kelly, Teratoma/metabolism/pathology, Time Factors, Transcription Factors/genetics/metabolism, Transduction, Vascular/metabolism/pathology/*physiopathology, Yin Liya
Tags: 2005, 70-kDa/metabolism, American journal of physiology. Heart and circulatory physiology, Angiotensin II/pharmacology, Animals, Antioxidants/*pharmacology, Bomser Joshua A, Cell Differentiation/drug effects, Cell Division/drug effects, Cells, Cultured, Department of Integrative Medical Sciences, Drug Interactions, Epidermal Growth Factor/pharmacology, Fibroblasts/*cytology/*drug effects, Male, Meszaros J Gary, Mitogen-Activated Protein Kinase 1/metabolism, Mitogen-Activated Protein Kinase 3/metabolism, Myocardium/*cytology, Naugle Jennifer E, NEOMED College of Medicine, Olson Erik R, Protein-Serine-Threonine Kinases/metabolism, Proto-Oncogene Proteins c-akt, Proto-Oncogene Proteins/metabolism, Rats, Resveratrol, Ribosomal Protein S6 Kinases, Signal Transduction/drug effects, Sprague-Dawley, Stilbenes/*pharmacology, Vasoconstrictor Agents/pharmacology, Zhang Xiaojin
Inhibition of dopamine and choline acetyltransferase concentrations in rat CNS neurons by rat alpha 1- and alpha 2-macroglobulins.
Tags: 1998, alpha-Macroglobulins/administration & dosage/*pharmacology, Animals, Cells, Choline O-Acetyltransferase/*antagonists & inhibitors, Corpus Striatum/drug effects/*enzymology/metabolism, Cultured, Dluzen D E, Dopamine Antagonists/*pharmacology, Dopamine/analysis/*metabolism, Enzyme Activation/drug effects, Hu Y Q, Injections, Intraventricular, Journal of neuroscience research, Koo P H, Liebl D J, Male, Neurons/drug effects/*enzymology/metabolism, Rats, Serotonin/pharmacology, Sprague-Dawley, Stereotaxic Techniques
Inhibition of human papillomavirus type 16 gene expression by nordihydroguaiaretic acid plant lignan derivatives.
Tags: 2000, Antiviral Agents/*pharmacology, Antiviral research, Callahan M, Craigo J, Cultured, DeLucia A L, Department of Integrative Medical Sciences, Female, Gene Expression Regulation, Genetic/drug effects, HIV Long Terminal Repeat/drug effects, Huang R C, Humans, Lignans/chemistry/pharmacology, Masoprocol/*analogs & derivatives/*pharmacology, NEOMED College of Medicine, Papillomaviridae/*genetics, Promoter Regions, Simian virus 40/genetics, Tumor Cells, Viral/*drug effects
Inhibition of nerve growth factor-stimulated neurite outgrowth by methylamine-modified alpha 2-macroglobulin.
Tags: 1992, alpha-Macroglobulins/metabolism/*pharmacology, Animals, Cells, Chick Embryo, Cultured, Drug Interactions, Female, Ganglia, Humans, Journal of neuroscience research, Koo P H, Liebl D J, Male, Methylamines/*pharmacology, Mice, Nerve Growth Factors/antagonists & inhibitors/metabolism/*pharmacology, Neurites/drug effects/*physiology/ultrastructure, Neurons/cytology/physiology, Placenta, Pregnancy, Spinal/physiology, Submandibular Gland
Inhibition of the G2/M transition of the cell cycle by methyl-2,5-dihydroxycinnamate in human lymphoid cells.
Tags: 1996, Biochemical and biophysical research communications, Cell Line, Cinnamates/*pharmacology, Cultured, G2 Phase/*drug effects, Humans, Jamison J M, Koch J A, Lymphocytes/cytology/*drug effects, Mitosis/*drug effects, Monocytes/cytology/drug effects, Rosenthal K S, Summers J L, Transformed, Tumor Cells
Interleukin IL-12 blocks a specific subset of the transcriptional profile responsive to UVB in epidermal keratinocytes.
Tags: *Keratinocytes/metabolism/radiation effects, *Ultraviolet Rays, 2006, Blumenberg Miroslav, Cell Culture Techniques, Cells, Cultured, Epidermal Cells, Gene Expression Regulation/drug effects, Genetic/*radiation effects, Humans, Interleukin-12/*genetics/*metabolism/pharmacology, Molecular immunology, Molenda Matthew, Mukkamala Lakshmi, Transcription