Browse Items (1073 total)
- Tags: Animals
An operant-based detection method for inferring tinnitus in mice.
Tags: *Conditioning, *Disease Models, *Inferior colliculus, *Mouse model, *Noise-induced hearing loss, *Operant conditioning, *Sodium salicylate, *Tinnitus, 2017, Acoustic Stimulation, Analysis of Variance, Animal, Animals, Auditory, Avoidance Learning, Bao Jianxin, Brain Stem/physiology, Department of Anatomy & Neurobiology, Electroshock, Equipment Design, Evoked Potentials, Female, Howie Benjamin, Inbred C57BL, Inferior Colliculi/physiopathology, Journal of neuroscience methods, Lei Debin, Male, Mice, Motor Activity, Mulvany Jessica, NEOMED College of Medicine, Neurons/physiology, Operant, Otoacoustic Emissions, Sivaramakrishnan Shobhana, Sodium Salicylate, Spontaneous/physiology, Tinnitus/*diagnosis/physiopathology, Tissue Culture Techniques, Voltage-Sensitive Dye Imaging, Zuo Hongyan
Orthosilicic acid, Si(OH)4, stimulates osteoblast differentiation in vitro by upregulating miR-146a to antagonize NF-kappaB activation.
Tags: *MicroRNA, *NF-kappaB, *Osteoblastic differentiation, *Osteoclastic differentiation, *Silicic acid, 2016, Abdelmagid Samir, Acta biomaterialia, Animals, Cell Differentiation/*drug effects, Department of Anatomy & Neurobiology, Humans, Mankoci Steven, Mesenchymal Stem Cells/*metabolism, Mice, MicroRNAs/*biosynthesis, Molenda Jim, Moussa Fouad M, Murphy William L, NEOMED College of Medicine, NF-kappa B/*metabolism, Osteoblasts/*metabolism, Osteogenesis/drug effects, RAW 264.7 Cells, Safadi Fayez F, Sahai Nita, Silicic Acid/*pharmacology, Ustriyana Putu, Zhang Nianli, Zhou Xianfeng
Orphan nuclear receptor oestrogen-related receptor gamma (ERRgamma) plays a key role in hepatic cannabinoid receptor type 1-mediated induction of CYP7A1 gene expression.
Tags: 2015, Animals, bile acid, Bile Acids and Salts/metabolism, Cannabinoid, cannabinoid receptors, CB1/agonists/genetics/*metabolism, Cells, Chiang John Y L, Choi Hueng-Sik, Cholesterol 7-alpha-Hydroxylase/*biosynthesis/genetics, cholesterol 7alpha-hydroxylase (CYP7A1), Cultured, Cytoplasmic and Nuclear/metabolism, Department of Integrative Medical Sciences, Drug Inverse Agonism, Estrogen/genetics/*metabolism, Ethanol/pharmacology, Gene Expression, Genetic, Glycerides/pharmacology, GSK5182, HEK293 Cells, Hepatocytes/metabolism, Humans, Inbred C57BL, Jeong Won-Il, Kim Don-Kyu, Kim Seong Heon, Knockout, Lee Chul-Ho, Lee In-Kyu, Lee Ji-Min, Liver/*metabolism, Mice, NEOMED College of Medicine, oestrogen-related receptor gamma (ERRgamma), orphan nuclear receptor, Park Seung Bum, Promoter Regions, Rats, Receptor, Receptors, small heterodimer partner (SHP), Sprague-Dawley, The Biochemical journal, Transcription, Zhang Yaochen
Identification of novel pathways that control farnesoid X receptor-mediated hypocholesterolemia.
Tags: 2010, Absorption, Anderson Jody, Animals, Biological, Cell Line, Cholesterol/*metabolism, Class B/*genetics/metabolism, Coronary Disease/metabolism, Cytoplasmic and Nuclear/*metabolism, Department of Integrative Medical Sciences, Edwards Peter A, Glucose/metabolism, Gonzalez Frank J, Hepatocyte Nuclear Factor 4/metabolism, Homeostasis, Humans, Lipoproteins/metabolism, Liver/metabolism, Ma Huiyan, Mice, Models, NEOMED College of Medicine, Receptors, Scavenger Receptors, The Journal of biological chemistry, Willson Timothy M, Yin Liya, Zhang Yanqiao
Loss of FXR protects against diet-induced obesity and accelerates liver carcinogenesis in ob/ob mice.
Tags: 2012, Adipose Tissue, Adiposity/genetics, Animals, Brown/pathology, Carcinoma/etiology/*genetics, Cell Transformation, Chen Wei-Dong, Cytoplasmic and Nuclear/*deficiency/genetics, Diet, Dietary Fats/metabolism, Edwards Peter A, Energy Metabolism/genetics, Female, Ge Xuemei, Gene Knockout Techniques, Glucose Intolerance/complications/genetics, Heemstra Lydia A, High-Fat/*adverse effects, Intestinal Absorption, Kasim Neda, Knockout, Leptin/deficiency/genetics, Liver Neoplasms/etiology/*genetics, Liver/pathology, Ma Huiyan, Male, Mice, Molecular endocrinology (Baltimore, Md.), Muscle, Neoplastic/genetics, Novak Colleen M, Obese, Obesity/*etiology/genetics, Receptors, Sex Factors, Skeletal/metabolism, Smith Joseph L, Weight Gain/genetics, Xu Jiesi, Zhang Yanqiao
Interleukin-1/toll-like receptor-induced nuclear factor kappa B signaling participates in intima hyperplasia after carotid artery balloon injury in goto-kakizaki rats: a potential target therapy pathway.
Tags: 2014, Animals, Carotid Artery Injuries/*metabolism, Hu Wenjing, Hyperplasia/*metabolism, Interleukin-1/*metabolism, Li Dongye, Male, NF-kappa B/*metabolism, Pan Defeng, PloS one, Rats, Signal Transduction/genetics/physiology, Toll-Like Receptors/*metabolism, Tunica Intima/*metabolism/*pathology, Wang Yi, Wistar, Wu Wanling, Xu Tongda, Zhang Xiaotian, Zhou Zhongmin
Differential protein acetylation assists import of excess SOD2 into mitochondria and mediates SOD2 aggregation associated with cardiac hypertrophy in the murine
Tags: *Cardiac-specific transgenic mouse, *Mitochondria, *Mitochondrial translocation, *Protein acetylation, *Protein aggregation, *SOD2, 2017, Acetylation, Animals, Cardiomegaly/*metabolism, Chen Chwen-Lih, Chen Yeong-Renn, Cytosol/*metabolism, Department of Integrative Medical Sciences, Free radical biology & medicine, Heart/*physiology, Jin Zhicheng, Kang Patrick T, Mice, Mitochondria/*metabolism, NEOMED College of Medicine, Pathological, Post-Translational, Protein Aggregation, Protein Folding, Protein Processing, Protein Transport, Reactive Oxygen Species/metabolism, Sirtuin 3/metabolism, Superoxide Dismutase/genetics/*metabolism, Transgenic, Zhang Liwen
Synthesis and biological evaluations of chalcones, flavones and chromenes as farnesoid x receptor (FXR) antagonists.
Tags: 2017, Animals, Antagonist, Benzopyrans/chemical synthesis/*pharmacology, Chalcones, Chalcones/chemical synthesis/*pharmacology, Chen Yuan, Chromenes, Cytoplasmic and Nuclear/*antagonists & inhibitors, Deng Ruitang, European journal of medicinal chemistry, Fang Weishuo, Farnesoid X receptor, Flavones/chemical synthesis/*pharmacology, Huan Yi, Jiang Qian, Liu Jinsong, Liu Shuainan, Liver Diseases/drug therapy, Liver/chemistry/*drug effects/metabolism, Mice, Receptors, Shen Zhufang, Sun Deyang, Tan Wenjuan, Triglycerides/analysis, Verma Ruchi, Wang Na, Wang Xing, Wong Chiwai, Xu Yang, Zhang Guoning, Zhang Yanqiao
Topographic organization of efferent projections of medial frontal cortex.
Morphological heterogeneity within the cingulate cortex in rat: a horseradish peroxidase transport study.
Tags: 1991, Animals, Biological Transport/physiology, Brain research, Cerebral Cortex/anatomy & histology/physiology, Diencephalon/anatomy & histology/physiology, Gyrus Cinguli/*anatomy & histology/metabolism/physiology, Horseradish Peroxidase/*pharmacokinetics, Injections, Male, Mesencephalon/anatomy & histology/physiology, Neural Pathways/anatomy & histology/physiology, Pons/anatomy & histology/physiology, Prosencephalon/anatomy & histology/physiology, Rats, Sprague-Dawley, Stuesse S L, Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate, Wheat Germ Agglutinins/*pharmacokinetics, Zeng D
Redox-dependent mechanisms in coronary collateral growth: the "redox window" hypothesis.
Tags: 2009, Angiotensin II/physiology, Animals, Antioxidants & redox signaling, Belmadani Souad, Carrao Ana Catarina Ribeiro, Chilian William M, Coronary Vessels/*growth & development/metabolism, Department of Integrative Medical Sciences, Humans, NEOMED College of Medicine, Ohanyan Vahagn, Oxidation-Reduction, Pung Yuh Fen, Reactive Oxygen Species/metabolism, Rocic Petra, Yun June
Surprising absence of heparin in the intestinal mucosa of baby pigs.
Tags: *Antibiotics, *heparin, *intestine, *microbiome, *pig, 2017, Animals, Anticoagulants/*metabolism, Chen Yin, Chondroitin Sulfates/metabolism, Department of Anatomy & Neurobiology, German Rebecca, Glycobiology, Gould Francois, Heparin/biosynthesis/isolation & purification/*metabolism, Heparitin Sulfate/metabolism, Intestinal Mucosa/*metabolism, Linhardt Robert J, Mast Cells/metabolism, Mikael Paiyz, NEOMED College of Medicine, Newborn/*metabolism, Ohlemacher Jocelyn, Stalcup Apryll M, Swine, Yu Yanlei, Zhang Fuming, Zhang Hong
Salvianolic Acid B Alleviates Heart Failure by Inactivating ERK1/2/GATA4 Signaling Pathway after Pressure Overload in Mice.
Tags: 2016, Animal, Animals, Aorta, Benzofurans/chemistry/*pharmacology, Blood Pressure/drug effects, Brain/blood, Cardiac/cytology/drug effects/metabolism, Cell Line, Chen Renshan, Chinese Herbal/chemistry/pharmacology, Disease Models, Drugs, GATA4 Transcription Factor/metabolism, Gu Weiwang, Heart Failure/metabolism/*pathology, Heart Ventricles/diagnostic imaging, Inbred C57BL, Male, Mice, Mitogen-Activated Protein Kinase 1/metabolism, Mitogen-Activated Protein Kinase 3/metabolism, Myocardium/metabolism/pathology, Myocytes, Natriuretic Peptide, Phosphorylation/drug effects, PloS one, Proto-Oncogene Proteins c-akt/metabolism, Qi Jianyong, Rats, Signal Transduction/*drug effects, Tan Yafang, Thoracic/surgery, Wu Jiashin, Yu Juan, Zhang Minzhou
Macrophage-Associated Osteoactivin/GPNMB Mediates Mesenchymal Stem Cell Survival, Proliferation, and Migration Via a CD44-Dependent Mechanism.
Tags: *CD44, *M2 MACROPHAGES, *MSC, *OA/GPNMB, 2016, Animals, Cell Movement/*physiology, Cell Proliferation/*physiology, Cell Survival/physiology, Department of Anatomy & Neurobiology, Eye Proteins/genetics/*metabolism, Hyaluronan Receptors/genetics/*metabolism, Journal of cellular biochemistry, Kim Min-Ho, Knockout, Macrophages/cytology/*metabolism, Malcuit Christopher, MAP Kinase Signaling System/physiology, Membrane Glycoproteins/genetics/*metabolism, Mesenchymal Stem Cells/cytology/*metabolism, Mice, NEOMED College of Medicine, Safadi Fayez F, Sondag Gregory R, Yu Bing
Glycoprotein Nonmelanoma Clone B Regulates the Crosstalk between Macrophages and Mesenchymal Stem Cells toward Wound Repair.
Tags: 2018, Administration, Alboslemy Talib, Animal, Animals, Cell Communication/*physiology, Cell Differentiation, Cells, Cultured, Cutaneous, Diabetes Mellitus, Disease Models, Eye Proteins/administration & dosage/genetics/*physiology, Humans, Inbred C57BL, Kim Min-Ho, Macrophages/*physiology, Male, Membrane Glycoproteins/administration & dosage/genetics/*physiology, Mesenchymal Stem Cells/*physiology, Mice, Recombinant Proteins/administration & dosage/genetics/metabolism, Safadi Fayez, Skin/*injuries/metabolism, The Journal of investigative dermatology, Type 2/complications/pathology, Wound Healing/*physiology, Yu Bing
Synthesis and Biological Evaluation of Pentacycloundecylamines and Triquinylamines as Voltage-Gated Calcium Channel Blockers.
Tags: 2016, Alicyclic/chemical synthesis/*chemistry/pharmacology, Amines/chemical synthesis/*chemistry/pharmacology, Animals, Apoptosis/drug effects, Archiv der Pharmazie, Calcium Channel Blockers/chemical synthesis/*chemistry/pharmacology, Calcium Channels, Calcium/*metabolism, Cell Survival/drug effects, Domingo Olwen C, Geldenhuys Werner J, Hydrocarbons, Hydrogen Peroxide/pharmacology, L-Lactate Dehydrogenase/metabolism, L-type calcium channel (LTCC) blockers, L-Type/*metabolism, Malan Sarel F, Multifunctional drugs, Neurodegeneration, PC12 Cells, Pentacycloundecylamine, Quinones/chemical synthesis/*chemistry/pharmacology, Rats, Structure-Activity Relationship, Triquinylamine, Van der Schyf Cornelis J, Young Lois-May
The stabilizing function of the tail during arboreal quadrupedalism.
Effects of support diameter and compliance on common marmoset (Callithrix jacchus) gait kinematics.
Tags: *Balance, *Branch stiffness, *Fine branch niche, *locomotion, *Stability, 2016, Animals, Biomechanical Phenomena, Callithrix/*physiology, Chadwell Brad A, Compliance, Computer-Assisted, Department of Anatomy & Neurobiology, Forelimb/physiology, Gait/*physiology, Hindlimb/physiology, Image Processing, Male, NEOMED College of Medicine, Stricklen Bethany M, The Journal of experimental biology, Video Recording, Young Jesse W
Developments in development: What have we learned from primate locomotor ontogeny?
Tags: *allometry, *gait mechanics, *life history, *locomotor independence, *ontogeny, 2018, American journal of physical anthropology, Animals, Anthropology, Biomechanical Phenomena/*physiology, Bone and Bones/physiology, Department of Anatomy & Neurobiology, Female, Gait/*physiology, Hand Strength/physiology, Humans, Locomotion/*physiology, Male, NEOMED College of Medicine, Phylogeny, Physical, Primates/*physiology, Shapiro Liza J, Young Jesse W
Tail function during arboreal quadrupedalism in squirrel monkeys (Saimiri boliviensis) and tamarins (Saguinus oedipus).
Tags: 2015, Animals, Chadwell Brad A, Department of Anatomy & Neurobiology, Extremities/anatomy & histology/*physiology, Fellmann Connie D, Gait, Journal of experimental zoology. Part A, Ecological genetics and physiology, Motor Activity/*physiology, NEOMED College of Medicine, Postural Balance, Russo Gabrielle A, Saguinus/*physiology, Saimiri/*physiology, Tail/*physiology, Thatikunta Meena A, Young Jesse W
Grasping primate development: Ontogeny of intrinsic hand and foot proportions in capuchin monkeys (Cebus albifrons and Sapajus apella).
Tags: *growth, *life history, *phalangeal index, *scaling, 2016, American journal of physical anthropology, Animals, Anthropology, Cebus/*anatomy & histology/physiology, Department of Anatomy & Neurobiology, Female, Finger Phalanges/*anatomy & histology/diagnostic imaging/physiology, Foot/*anatomy & histology/diagnostic imaging/physiology, Hand Strength/*physiology, Hand/*anatomy & histology/diagnostic imaging/physiology, Heard-Booth Amber N, Linear Models, NEOMED College of Medicine, Physical, Pregnancy, Toe Phalanges/*anatomy & histology/diagnostic imaging/physiology, Young Jesse W
Ontogeny of long bone geometry in capuchin monkeys (Cebus albifrons and Cebus apella): implications for locomotor development and life history.
Tags: 2010, Adaptation, Animals, Biological/*physiology, Biology letters, Biomechanical Phenomena, Body Size, Bone Development/*physiology, Cebus/anatomy & histology/*growth & development/physiology, Department of Anatomy & Neurobiology, Femur/diagnostic imaging/*growth & development, Fernandez David, Fleagle John G, Humerus/diagnostic imaging/*growth & development, Locomotion/*physiology, NEOMED College of Medicine, Radiography, Regression Analysis, Species Specificity, Young Jesse W
Limb bone morphology, bone strength, and cursoriality in lagomorphs.
Tags: *Arm Bones/anatomy & histology/physiology, *Lagomorpha/anatomy & histology/physiology, *Leg Bones/anatomy & histology/physiology, *Tensile Strength, 2014, Animals, Bone Density/physiology, Danczak Robert, Department of Anatomy & Neurobiology, Fellmann Connie D, Journal of anatomy, Mechanical, mechanical advantage, mineralization, NEOMED College of Medicine, Pliability, polar section modulus, robusticity, Running/*physiology, Russo Gabrielle A, safety factor, Stress, Tomography, X-Ray Computed, Young Jesse W
Ontogeny of limb force distribution in squirrel monkeys (Saimiri boliviensis): insights into the mechanical bases of primate hind limb dominance.
Tags: *locomotion, 2012, Age Factors, Animals, Biological, Biomechanical Phenomena, Department of Anatomy & Neurobiology, Female, Journal of human evolution, Leg/anatomy & histology/*growth & development/*physiology, Models, NEOMED College of Medicine, Saimiri/anatomy & histology/*growth & development/*physiology, Videotape Recording, Weight-Bearing, Young Jesse W
Gait selection and the ontogeny of quadrupedal walking in squirrel monkeys (Saimiri boliviensis).
Tags: 2012, American journal of physical anthropology, Animals, Biomechanical Phenomena/physiology, Body Size, Cross-Sectional Studies, Department of Anatomy & Neurobiology, Female, Gait/*physiology, Logistic Models, NEOMED College of Medicine, Saimiri/*physiology, Walking/*physiology, Young Jesse W
Signal Transduction Mechanisms of Alcoholic Fatty Liver Disease: Emer ging Role of Lipin-1.
Tags: 2017, alcoholic fatty liver disease, Alcoholic/*metabolism/pathology, AMP-Activated Protein Kinases/metabolism, Animals, Current molecular pharmacology, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Ethanol/chemistry/*metabolism, Fatty Liver, Humans, Inflammation, Inflammation/metabolism, Jogasuria Alvin, Lee Kwangwon, Lee Yoon-Kwang, Lipid Metabolism, Lipin-1, Liver/metabolism, NEOMED College of Graduate Studies, NEOMED College of Medicine, NEOMED College of Pharmacy, Phosphatidate Phosphatase/*metabolism, Sadana Prabodh, Signal Transduction, Sirtuin 1/metabolism, transcriptional regulators, Wu Jiashin, You Min, Zhang Yanqiao
Induction of vascular progenitor cells from endothelial cells stimulates coronary collateral growth.
Tags: *Collateral Circulation, *Coronary Circulation, 2012, Animal, Animals, Bailey Erin, Biomarkers/metabolism, Cell Differentiation, Cell Lineage, Cells, Chilian William M, Circulation research, Coronary Occlusion/genetics/metabolism/pathology/physiopathology/*surgery, Coronary Vessels/metabolism/pathology/*physiopathology, Cultured, Delucia Angelo, Department of Integrative Medical Sciences, Developmental, Disease Models, Endothelial Cells/metabolism/pathology/*transplantation, Enrick Molly, Epigenesis, Gene Expression Profiling, Gene Expression Regulation, Genetic, Guarini Giacinta, Induced Pluripotent Stem Cells/metabolism/*transplantation, Kolz Christopher L, Mice, Muscle, Myocytes, NEOMED College of Medicine, Neovascularization, Ohanyan Vahagn, Physiologic, Pung Yuh Fen, Rats, Regenerative Medicine/methods, Regional Blood Flow, Reverse Transcriptase Polymerase Chain Reaction, SCID, Smooth, Smooth Muscle/metabolism/pathology/*transplantation, Sprague-Dawley, Stevanov Kelly, Teratoma/metabolism/pathology, Time Factors, Transcription Factors/genetics/metabolism, Transduction, Vascular/metabolism/pathology/*physiopathology, Yin Liya
Hepatic hepatocyte nuclear factor 4alpha is essential for maintaining triglyceride and cholesterol homeostasis.
Tags: 2011, Adenoviridae/genetics, Animal, Animals, Arteriosclerosis, thrombosis, and vascular biology, Cells, Cholesterol, Cholesterol/*metabolism, Cultured, Department of Integrative Medical Sciences, Edwards Peter A, Fatty Liver/metabolism/physiopathology, Ge Xuemei, HDL/metabolism, Hepatocyte Nuclear Factor 4/drug effects/genetics/*physiology, Hepatocytes/cytology/*metabolism, Homeostasis/genetics/*physiology, Inbred C57BL, Lipid Metabolism/genetics/physiology, Ma Huiyan, Mice, Models, NEOMED College of Medicine, RNA, Small Interfering/genetics/pharmacology, Triglycerides/*metabolism, VLDL/metabolism, Yin Liya, Zhang Yanqiao
miR-217 regulates ethanol-induced hepatic inflammation by disrupting sirtuin
Tags: 2015, Alcoholic/genetics/*metabolism, Animals, Chromatin Immunoprecipitation, Davidson Nicholas O, Department of Pharmaceutical Sciences, Enzyme-Linked Immunosorbent Assay, Ethanol/toxicity, Fatty Liver/metabolism, Hepatitis, Immunoblotting, Inbred C57BL, Inflammation/genetics/*metabolism, Jogasuria Alvin, Kupffer Cells/metabolism, Liang Xiaomei, Lipopolysaccharides/toxicity, Male, Mice, MicroRNAs/*metabolism, NEOMED College of Pharmacy, Nuclear Proteins/*metabolism, Phosphatidate Phosphatase/*metabolism, Real-Time Polymerase Chain Reaction, Signal Transduction/*physiology, Sirtuin 1/*metabolism, The American journal of pathology, Transfection, Yin Huquan, You Min
Stimulation of distal airspace fluid clearance in guinea pigs involves bumetanide-sensitive ion transport.
Tags: *Ion Transport, 2004, Absorption, Adrenergic, Adrenergic beta-Antagonists/pharmacology, American journal of obstetrics and gynecology, Animals, beta/physiology, Body Fluids/*metabolism, Bumetanide/*pharmacology, Diuretics/*pharmacology, Epinephrine/blood, Epithelium, Fetus/metabolism, Folkesson Hans G, Gestational Age, Guinea Pigs, Lung/*embryology/metabolism, Newborn, Norlin Andreas, Propranolol/pharmacology, Receptors, Ye Xin
IL-1beta stimulates alveolar fluid absorption in fetal guinea pig lungs via the hypothalamus-pituitary-adrenal gland axis.
Tags: 2004, Acharya Reshma, Adrenocorticotropic Hormone/blood, American journal of physiology. Lung cellular and molecular physiology, Animals, Epinephrine/blood, Epithelial Sodium Channels, Extravascular Lung Water/*metabolism, Female, Folkesson Hans G, Guinea Pigs, Hamilton Sarah E, Herbert Jonathan B, Hydrocortisone/blood, Hypothalamo-Hypophyseal System/*physiology, Interleukin-1/blood/*pharmacology, Norepinephrine/blood, Pituitary-Adrenal System/*physiology, Pregnancy, Pulmonary Alveoli/*drug effects/embryology/*metabolism, Sodium Channels/metabolism, Sodium-Potassium-Exchanging ATPase/metabolism, Ye Xin
Circuitry underlying spectrotemporal integration in the auditory midbrain.
Tags: 2011, Acoustic Stimulation/*methods, Animals, Auditory Pathways/*physiology, Chiroptera, College of Anatomy & Neurobiology, Department of Anatomy & Neurobiology, Female, Male, Mesencephalon/*physiology, NEOMED College of Medicine, Nerve Net/*physiology, Schofield Brett R, The Journal of neuroscience : the official journal of the Society for Neuroscience, Time Factors, Wenstrup Jeffrey J, Yavuzoglu Asuman
Substrates of auditory frequency integration in a nucleus of the lateral lemniscus.
Tags: 2010, Acoustic Stimulation, Action Potentials, Animals, Auditory Pathways/*physiology, Brain Stem/anatomy & histology/*physiology, Chiroptera/*physiology, College of Anatomy & Neurobiology, Department of Anatomy & Neurobiology, Glycine/physiology, NEOMED College of Medicine, Neuroscience, Schofield B R, Wenstrup J J, Yavuzoglu A
On the mechanism of bile acid inhibition of rat sterol 12alpha-hydroxylase gene (CYP8B1) transcription: roles of alpha-fetoprotein transcription factor and hepatocyte nuclear factor 4alpha.
Tags: *DNA-Binding Proteins, 2002, alpha-Fetoproteins/genetics/*physiology, Animals, Base Sequence, Bile Acids and Salts/*pharmacology, Biochimica et biophysica acta, Cattle, Chiang John Y L, Cytochrome P-450 Enzyme System/*genetics, Department of Integrative Medical Sciences, DNA, Eggertsen Gosta, Enzymologic/*drug effects/physiology, Gene Expression Regulation, Genetic, Genetic/*drug effects, Hepatocyte Nuclear Factor 4, Messenger/genetics, NEOMED College of Medicine, Phosphoproteins/genetics/*physiology, Promoter Regions, Rats, RNA, Sprague-Dawley, Steroid 12-alpha-Hydroxylase, Steroid Hydroxylases/*genetics, Transcription, Transcription Factors/genetics/*physiology, Yang Yizeng, Zhang Ming
A novel role for Bcl-2 associated-athanogene-1 (Bag-1) in regulation of the endoplasmic reticulum stress response in mammalian chondrocytes.
Tags: *Gene Expression Regulation, 2007, Animals, Apoptosis, Biological, Carlson Sara G, Cell Proliferation, Chondrocytes/*metabolism/pathology, Collagen Type II/metabolism, Department of Anatomy & Neurobiology, DNA-Binding Proteins/*metabolism/physiology, Endoplasmic Reticulum/metabolism, Horton Walter E Jr, Journal of cellular biochemistry, McBurney Denise, Models, NEOMED College of Medicine, Phenotype, Rats, RNA Interference, Subcellular Fractions/metabolism, Tang Shou-Ching, Time Factors, Transcription Factors/*metabolism/physiology, Transfection, Yang Ling
Multiple signals induce endoplasmic reticulum stress in both primary and immortalized chondrocytes resulting in loss of differentiation, impaired cell growth, and apoptosis.
Tags: 2005, Animals, Annexin A5/metabolism, Anti-Bacterial Agents/metabolism, Apoptosis/*physiology, Biomarkers, Carlson Sara G, Caspase 12, Caspases/metabolism, CCAAT-Enhancer-Binding Proteins/metabolism, Cell Differentiation/*physiology, Cells, Chondrocytes/cytology/*physiology, Collagen Type II/metabolism, Cultured, Department of Anatomy & Neurobiology, DNA Fragmentation, Endoplasmic Reticulum/*metabolism, Extracellular Matrix/metabolism, Gene Expression Regulation, Glucose/metabolism, Horton Walter E Jr, McBurney Denise, NEOMED College of Medicine, Proliferating Cell Nuclear Antigen/metabolism, Rats, Signal Transduction/*physiology, Thapsigargin/metabolism, The Journal of biological chemistry, Transcription Factor CHOP, Transcription Factors/metabolism, Tunicamycin/metabolism, Yang Ling
The acute effects of methylenedioxymethamphetamine on dopamine release in the awake-behaving rat.
Tags: 1988, 3, 4-Dihydroxyphenylacetic Acid/metabolism, 4-methylenedioxyamphetamine, 4-Methylenedioxyamphetamine/analogs & derivatives/*pharmacology, Amphetamines/*pharmacology, Animals, Brain/drug effects/metabolism, Caudate Nucleus/drug effects/metabolism, Consciousness, Dopamine/*metabolism, European journal of pharmacology, Inbred Strains, Male, N-Methyl-3, Nucleus Accumbens/drug effects/metabolism, Rats, Spanos L J, Yamamoto B K
A neurochemical heterogeneity of the rat striatum as measured by in vivo electrochemistry and microdialysis.
Tags: 1990, 3, 4-Dihydroxyphenylacetic Acid/metabolism, Amphetamines/*pharmacology, Animals, Brain research, Corpus Striatum/*metabolism, Dopamine D2, Dopamine/*metabolism, Dopamine/drug effects, Electrochemistry, Inbred Strains, Male, Pehek E A, Rats, Receptors, Sulpiride/*pharmacology, Yamamoto B K
Bcl-2 positively regulates Sox9-dependent chondrocyte gene expression by suppressing the MEK-ERK1/2 signaling pathway.
Tags: *Gene Expression Regulation, 2005, Adenoviridae/genetics, Animals, Apoptosis, beta-Galactosidase/metabolism, Blotting, Butadienes/pharmacology, Caspase Inhibitors, Cell Differentiation, Cell Line, Chondrocytes/*metabolism, Collagen Type II/metabolism, Department of Anatomy & Neurobiology, Down-Regulation, Enzyme Inhibitors/pharmacology, Fibroblasts/metabolism, Fluorescence, Genetic, High Mobility Group Proteins/*metabolism, Horton Walter E Jr, Lac Operon, Luciferases/metabolism, MAP Kinase Kinase Kinases/*metabolism, McBurney Denise, Messenger/metabolism, Microscopy, Mitogen-Activated Protein Kinase 1/*metabolism, Mitogen-Activated Protein Kinase 3/*metabolism, NEOMED College of Medicine, NF-kappa B/metabolism, Nitriles/pharmacology, Phenotype, Phosphorylation, Promoter Regions, Protein Kinase C-alpha, Protein Kinase C/antagonists & inhibitors, Proteoglycans/metabolism, Proto-Oncogene Proteins c-bcl-2/*metabolism, Rats, Reverse Transcriptase Polymerase Chain Reaction, RNA, Signal Transduction, Small Interfering/metabolism, SOX9 Transcription Factor, Sprague-Dawley, The Journal of biological chemistry, Time Factors, Transcription, Transcription Factors/*metabolism, Transfection, Western, Yagi Rieko
A metabolic stress-inducible miR-34a-HNF4alpha pathway regulates lipid and lipoprotein metabolism.
Tags: 2015, Animals, Apolipoproteins E/genetics, Atherosclerosis/genetics/metabolism, Department of Integrative Medical Sciences, Diabetes Mellitus, Experimental/genetics/metabolism, Hep G2 Cells, Hepatocyte Nuclear Factor 4/*genetics/metabolism, Humans, Knockout, LDL/genetics, Li Yuanyuan, Lipid Metabolism/*genetics, Lipoproteins/metabolism, Liver/metabolism, Mice, MicroRNAs/*genetics/metabolism, Middle Aged, Nature communications, NEOMED College of Medicine, Non-alcoholic Fatty Liver Disease/*genetics/metabolism, Physiological/*genetics, Receptors, Stress, Triglycerides/*metabolism, Xu Jiesi, Xu Yang, Yin Liya, Zalzala Munaf, Zhang Yanqiao