Browse Items (117 total)
- Tags: Cells
Glycoprotein Nonmelanoma Clone B Regulates the Crosstalk between Macrophages and Mesenchymal Stem Cells toward Wound Repair.
Tags: 2018, Administration, Alboslemy Talib, Animal, Animals, Cell Communication/*physiology, Cell Differentiation, Cells, Cultured, Cutaneous, Diabetes Mellitus, Disease Models, Eye Proteins/administration & dosage/genetics/*physiology, Humans, Inbred C57BL, Kim Min-Ho, Macrophages/*physiology, Male, Membrane Glycoproteins/administration & dosage/genetics/*physiology, Mesenchymal Stem Cells/*physiology, Mice, Recombinant Proteins/administration & dosage/genetics/metabolism, Safadi Fayez, Skin/*injuries/metabolism, The Journal of investigative dermatology, Type 2/complications/pathology, Wound Healing/*physiology, Yu Bing
Hepatic hepatocyte nuclear factor 4alpha is essential for maintaining triglyceride and cholesterol homeostasis.
Tags: 2011, Adenoviridae/genetics, Animal, Animals, Arteriosclerosis, thrombosis, and vascular biology, Cells, Cholesterol, Cholesterol/*metabolism, Cultured, Department of Integrative Medical Sciences, Edwards Peter A, Fatty Liver/metabolism/physiopathology, Ge Xuemei, HDL/metabolism, Hepatocyte Nuclear Factor 4/drug effects/genetics/*physiology, Hepatocytes/cytology/*metabolism, Homeostasis/genetics/*physiology, Inbred C57BL, Lipid Metabolism/genetics/physiology, Ma Huiyan, Mice, Models, NEOMED College of Medicine, RNA, Small Interfering/genetics/pharmacology, Triglycerides/*metabolism, VLDL/metabolism, Yin Liya, Zhang Yanqiao
Hepatocyte growth factor signaling pathway inhibits cholesterol 7alpha-hydroxylase and bile acid synthesis in human hepatocytes.
Tags: 2007, Bile Acids and Salts/*biosynthesis, Cells, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*biosynthesis, Cultured, Department of Integrative Medical Sciences, Ellis Ewa, Hepatocyte Growth Factor/*metabolism, Hepatocytes/*metabolism, Hepatology (Baltimore, Md.), Humans, NEOMED College of Medicine, Signal Transduction, Song Kwang-Hoon, Strom Stephen
Histochemical analyses of tissue-engineered human menisci.
Tags: *Tissue Scaffolds, 2009, Animals, Cell Differentiation/physiology, Cell Proliferation, Cell Shape/physiology, Cells, Chondrocytes/*cytology/*metabolism/transplantation, Chondrogenesis/physiology, Collagen/metabolism, Connective tissue research, Cultured, Doherty Alison, Fibrocartilage/cytology/metabolism/transplantation, Graft Survival/physiology, Heterologous/methods, Histocytochemistry, Humans, Jacquet Robin, Landis William J, Leeson Mark C, Lowder Elizabeth, Male, Menisci, Mice, Middle Aged, Nude, Phenotype, Polyglycolic Acid/pharmacology/therapeutic use, Schoenfeld Andrew J, Tibial/*cytology/*metabolism/transplantation, Tissue Engineering/*methods, Transplantation
Histone deacetylase inhibitor vorinostat (SAHA, MK0683) perturb miR-9-MCPIP1 axis to block IL-1beta-induced IL-6 expression in human OA chondrocytes.
Tags: *IL-6, *MCPIP1, *miRNA, *OSTEOARTHRITIS, *Vorinostat, 2017, Adult, Aged, CCAAT-Enhancer-Binding Proteins/genetics/metabolism, Cells, Chondrocytes/*metabolism/pathology, Connective tissue research, Cultured, Department of Anatomy & Neurobiology, Female, Gene Expression Regulation/*drug effects, Genetic, Haqqi Tariq M, Humans, Hydroxamic Acids/*pharmacology, Interleukin-1beta/genetics/*metabolism, Interleukin-6/genetics/*metabolism, Makki Mohammad S, Male, MicroRNAs/genetics/*metabolism, Middle Aged, NEOMED College of Medicine, Osteoarthritis/drug therapy/genetics/*metabolism/pathology, Promoter Regions, Ribonucleases/*biosynthesis/genetics, Transcription Factors/*biosynthesis/genetics, Vorinostat
Hyperglycemia enhances function and differentiation of adult rat cardiac fibroblasts.
Tags: *Cell Differentiation, 2014, Adapala Ravi K, Animals, Blood Glucose/metabolism, Bryant Jennifer E, Canadian journal of physiology and pharmacology, cardiac fibroblast, Cell Movement, Cell Proliferation, Cells, Collagen, Collagen/metabolism, collagene, concentration elevee de glucose, Cultured, Department of Integrative Medical Sciences, diabete, Diabetes, fibroblaste cardiaque, Fibroblasts/*metabolism/pathology, Fibrosis, high glucose, Hyperglycemia/*metabolism/pathology, Luther Daniel J, Male, Meszaros J Gary, migration, Myocardium/*metabolism/pathology, myofibroblast, myofibroblastes, NEOMED College of Medicine, Petersen Kyle A, proliferation, Rats, Shamhart Patricia E, Signal Transduction, Sprague-Dawley, Thodeti Charles K
Immune response to nonspecific and altered tissue antigens in soft tissue allografts.
Tags: 1996, Anti-Infective Agents, Articular/immunology/physiology/*transplantation, Biomechanical Phenomena, Bone Transplantation/*immunology, Cells, Clinical orthopaedics and related research, Cultured, Ethanol/pharmacology, Fibroblasts/drug effects, Homologous, Humans, Hydrogen Peroxide/pharmacology, Ligaments, Local/pharmacology, Pinkowski J L, Povidone-Iodine/pharmacology, Rodrigo J J, Sharkey N A, Therapeutic Irrigation, Tissue Preservation, Transplantation, Vasseur P B
Impact Of Parturition On Chemokine Homing Factor Expression In The Vaginal Distention Model Of Stress Urinary Incontinence
Tags: 2013, animal-model, Butler R S, Cells, Cytokines, Damaser M S, deficiency, Delivery, Female, Hijaz A, Journal Article or Conference Abstract Publication, Journal of Urology, Kuang M, Lenis A T, Obstetric, Penn M S, Pregnancy, Rackley R, Rats, simulated childbirth injuries, urethra, urogenital organs, Urology & Nephrology, vagina, Women, Woo L L, Wood H M, wounds and injuries
Induction of vascular progenitor cells from endothelial cells stimulates coronary collateral growth.
Tags: *Collateral Circulation, *Coronary Circulation, 2012, Animal, Animals, Bailey Erin, Biomarkers/metabolism, Cell Differentiation, Cell Lineage, Cells, Chilian William M, Circulation research, Coronary Occlusion/genetics/metabolism/pathology/physiopathology/*surgery, Coronary Vessels/metabolism/pathology/*physiopathology, Cultured, Delucia Angelo, Department of Integrative Medical Sciences, Developmental, Disease Models, Endothelial Cells/metabolism/pathology/*transplantation, Enrick Molly, Epigenesis, Gene Expression Profiling, Gene Expression Regulation, Genetic, Guarini Giacinta, Induced Pluripotent Stem Cells/metabolism/*transplantation, Kolz Christopher L, Mice, Muscle, Myocytes, NEOMED College of Medicine, Neovascularization, Ohanyan Vahagn, Physiologic, Pung Yuh Fen, Rats, Regenerative Medicine/methods, Regional Blood Flow, Reverse Transcriptase Polymerase Chain Reaction, SCID, Smooth, Smooth Muscle/metabolism/pathology/*transplantation, Sprague-Dawley, Stevanov Kelly, Teratoma/metabolism/pathology, Time Factors, Transcription Factors/genetics/metabolism, Transduction, Vascular/metabolism/pathology/*physiopathology, Yin Liya
Inhibition of cardiac fibroblast proliferation and myofibroblast differentiation by resveratrol.
Tags: 2005, 70-kDa/metabolism, American journal of physiology. Heart and circulatory physiology, Angiotensin II/pharmacology, Animals, Antioxidants/*pharmacology, Bomser Joshua A, Cell Differentiation/drug effects, Cell Division/drug effects, Cells, Cultured, Department of Integrative Medical Sciences, Drug Interactions, Epidermal Growth Factor/pharmacology, Fibroblasts/*cytology/*drug effects, Male, Meszaros J Gary, Mitogen-Activated Protein Kinase 1/metabolism, Mitogen-Activated Protein Kinase 3/metabolism, Myocardium/*cytology, Naugle Jennifer E, NEOMED College of Medicine, Olson Erik R, Protein-Serine-Threonine Kinases/metabolism, Proto-Oncogene Proteins c-akt, Proto-Oncogene Proteins/metabolism, Rats, Resveratrol, Ribosomal Protein S6 Kinases, Signal Transduction/drug effects, Sprague-Dawley, Stilbenes/*pharmacology, Vasoconstrictor Agents/pharmacology, Zhang Xiaojin
Inhibition of dopamine and choline acetyltransferase concentrations in rat CNS neurons by rat alpha 1- and alpha 2-macroglobulins.
Tags: 1998, alpha-Macroglobulins/administration & dosage/*pharmacology, Animals, Cells, Choline O-Acetyltransferase/*antagonists & inhibitors, Corpus Striatum/drug effects/*enzymology/metabolism, Cultured, Dluzen D E, Dopamine Antagonists/*pharmacology, Dopamine/analysis/*metabolism, Enzyme Activation/drug effects, Hu Y Q, Injections, Intraventricular, Journal of neuroscience research, Koo P H, Liebl D J, Male, Neurons/drug effects/*enzymology/metabolism, Rats, Serotonin/pharmacology, Sprague-Dawley, Stereotaxic Techniques
Inhibition of nerve growth factor-stimulated neurite outgrowth by methylamine-modified alpha 2-macroglobulin.
Tags: 1992, alpha-Macroglobulins/metabolism/*pharmacology, Animals, Cells, Chick Embryo, Cultured, Drug Interactions, Female, Ganglia, Humans, Journal of neuroscience research, Koo P H, Liebl D J, Male, Methylamines/*pharmacology, Mice, Nerve Growth Factors/antagonists & inhibitors/metabolism/*pharmacology, Neurites/drug effects/*physiology/ultrastructure, Neurons/cytology/physiology, Placenta, Pregnancy, Spinal/physiology, Submandibular Gland
Interaction of nerve growth factor with murine alpha-macroglobulin.
Interleukin IL-12 blocks a specific subset of the transcriptional profile responsive to UVB in epidermal keratinocytes.
Tags: *Keratinocytes/metabolism/radiation effects, *Ultraviolet Rays, 2006, Blumenberg Miroslav, Cell Culture Techniques, Cells, Cultured, Epidermal Cells, Gene Expression Regulation/drug effects, Genetic/*radiation effects, Humans, Interleukin-12/*genetics/*metabolism/pharmacology, Molecular immunology, Molenda Matthew, Mukkamala Lakshmi, Transcription
Interleukin-1beta induced Stress Granules Sequester COX-2 mRNA and Regulates its Stability and Translation in Human OA Chondrocytes.
Tags: *Protein Biosynthesis, 2016, Ansari Mohammad Y, Cells, Chondrocytes/drug effects/metabolism/pathology, Cultured, Cyclooxygenase 2/*genetics, Department of Anatomy & Neurobiology, Dinoprostone/genetics, Fluorescence, Gene Expression Regulation, Haqqi Tariq M, Humans, Immunoprecipitation, In Situ Hybridization, Interleukin-1beta/administration & dosage/*genetics, Messenger/genetics, NEOMED College of Medicine, Nitric Oxide/metabolism, Osteoarthritis/drug therapy/*genetics/pathology, RNA, Scientific reports
J-LEAPS vaccines initiate murine Th1 responses by activating dendritic cells.
Tags: *Antigen Presentation, 2010, Adoptive Transfer, Animals, Bailey E, Cells, Cohen P A, Cultured, Dendritic Cells/*immunology, Epitopes, Female, gag Gene Products, Herpes Simplex/immunology/prevention & control, Herpesvirus 1, Human Immunodeficiency Virus/immunology, Human/immunology, Inbred A, Inbred C57BL, Interferon-gamma/immunology, Interleukin-12/immunology, Koski G K, Mice, Moore F B-G, Paustian C C, Rosenthal K S, T-Lymphocyte/immunology, Taylor P R, Th1 Cells/*immunology, Vaccine, Viral Envelope Proteins/immunology, Viral Vaccines/*immunology, Zimmerman D H
Leptin augments recruitment of IRF-1 and CREB to thrombospondin-1 gene promoter in vascular smooth muscle cells in vitro.
Tags: *cAMP response element-binding protein, *interferon regulatory factor-1, *leptin, *thrombospondin-1, *Transcription, *vascular smooth muscle cells, 2016, American journal of physiology. Cell physiology, Binding Sites/genetics, Cells, Chromatin Immunoprecipitation/methods, Cultured, Cyclic AMP Response Element-Binding Protein/*metabolism, Department of Integrative Medical Sciences, Ganguly Rituparna, Gene Expression Regulation/genetics, Genetic/genetics, Humans, Interferon Regulatory Factor-1/*metabolism, Leptin/*metabolism, Muscle, Mutagenesis, Myocytes, NEOMED College of Medicine, Promoter Regions, Raman Priya, Response Elements/genetics, Sahu Soumyadip, Site-Directed/methods, Smooth, Smooth Muscle/*metabolism, Thrombospondin 1/*genetics/*metabolism, Transcription, Transcriptional Activation/genetics, Transfection/methods, Up-Regulation/genetics, Vascular/*metabolism
LPS-TLR4 Pathway Mediates Ductular Cell Expansion in Alcoholic Hepatitis.
Tags: 2016, Affo Silvia, Alcoholic/*immunology, Altamirano Jose, Animals, Arroyo Vicente, Bataller Ramon, Caballeria Juan, Cell Proliferation, Cells, Chen Jiegen, Collagen/genetics/metabolism, Common/*pathology, Crews Fulton, Cultured, Department of Pharmaceutical Sciences, Dumitru Raluca, Female, Gene Expression Profiling, Gene Expression Regulation, Gines Pere, Hepatic Duct, Hepatitis, Hepatocytes/*metabolism/pathology, Humans, Inbred BALB C, Keratins, Knockout, Lipopolysaccharides/metabolism, Lozano Juan Jose, Male, Matsushita Hiroshi, Mice, Middle Aged, Morales-Ibanez Oriol, NEOMED College of Pharmacy, Odena Gemma, Rautou Pierre-Emmanuel, Rodrigo-Torres Daniel, Sancho-Bru Pau, Scientific reports, Seki Ekihiro, Signal Transduction, Toll-Like Receptor 4/genetics/*metabolism, Type I/genetics/*metabolism, Valla Dominique, You Min, Zou Jian
Lyotropic chromonic liquid crystals for biological sensing applications
Tags: 2005, biosensor, Cells, Chemistry, chromonics, Crystallography, Doane K J, Ishikawa T, Journal Article, Lavrentovich O D, ligand-receptor binding, liquid crystal, Materials Science, Molecular Crystals and Liquid Crystals, Niehaus G D, Schneider T, Shiyanovskii S V, Smalyukh I I, Woolverton C J
Mechanism of vitamin D receptor inhibition of cholesterol 7alpha-hydroxylase gene transcription in human hepatocytes.
Tags: 2009, Base Sequence, Calcitriol/drug effects/genetics/*physiology, Cell Line, Cells, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*genetics, Cultured, Department of Integrative Medical Sciences, DNA Primers, Drug metabolism and disposition: the biological fate of chemicals, Electrophoretic Mobility Shift Assay, Gene Knockdown Techniques, Genetic/*physiology, Han Shuxin, Hepatocytes/*drug effects/enzymology, Humans, Immunoprecipitation, Lithocholic Acid/pharmacology, Messenger/genetics, NEOMED College of Medicine, Polymerase Chain Reaction, Receptors, RNA, Small Interfering, Transcription, Tumor, Two-Hybrid System Techniques
Mechanisms of Chinese Medicine Xinmailong's protection against heart failure in pressure-overloaded mice and cultured cardiomyocytes.
Tags: 2017, Animal, Animals, Cardiac/cytology/*drug effects/metabolism, Cell Nucleus/metabolism, Cell Survival/drug effects, Cells, Chen Renshan, Chen Yanfen, Chinese Herbal/*administration & dosage/pharmacology, Constriction, Cultured, Disease Models, Drugs, Echocardiography, GABA Plasma Membrane Transport Proteins/*metabolism, Gene Expression Regulation/drug effects, Glycogen Synthase Kinase 3 beta/metabolism, Gu Weiwang, Heart Failure/etiology/metabolism/physiopathology/*prevention & control, Humans, Liu Qin, Lu Jun, MAP Kinase Signaling System/drug effects, Mice, Myocytes, Pathologic, Phosphorylation, Proto-Oncogene Proteins c-akt/metabolism, Qi Jianyong, Rats, Scientific reports, Tan Yafang, Wu Jiashin, Xu Wen, Yu Juan, Zhang Minzhou
Mechanosensitive transient receptor potential vanilloid 4 regulates Dermatophagoides farinae-induced airway remodeling via 2 distinct pathways modulating matrix synthesis and degradation.
Tags: *Airway Remodeling, *fibronectin, *myofibroblasts, *PAI-1, *PI3K, *TGF-beta1, 2017, Adult, Al-Azzam Nosayba, Animals, Asthma/etiology/genetics/*metabolism/pathology, Cells, Cultured, Department of Integrative Medical Sciences, Dermatophagoides farinae/immunology, Duah Ernest, Extracellular Matrix/*metabolism/pathology, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Fibroblasts/metabolism, Fibronectins/*metabolism, Gombedza Farai, Hexter Madison, Humans, Inbred C57BL, Kondeti Vinay, Koppes Stephanie, Male, Mice, NEOMED College of Medicine, Paruchuri Sailaja, Patil Prachi, Phillips Daniel, Phosphatidylinositol 3-Kinases/metabolism, Plasminogen Activator Inhibitor 1/metabolism, Thodeti Charles K, Transforming Growth Factor beta/metabolism, TRPV Cation Channels/genetics/*metabolism
Methods and insights from the characterization of osteoprogenitor cells of bats (Mammalia: Chiroptera).
Tags: 2016, Animals, Ball H C, Bone Marrow Cells/cytology, Cell Differentiation/genetics, Cell Proliferation, Cells, Cellular Reprogramming, Chiroptera, Cooper L N, Core Binding Factor Alpha 1 Subunit/genetics/metabolism, Cultured, Department of Anatomy & Neurobiology, Inbred C57BL, Mbimba T, Mice, Moussa F M, NEOMED College of Medicine, Orman R, Osteoblasts/cytology/*metabolism, Osteocalcin/genetics/metabolism, Osteogenesis/*genetics, Real-Time Polymerase Chain Reaction, Safadi F F, Stem cell research, Stem Cells/*cytology/metabolism, Transcription Factors/genetics/metabolism
Microglial Function and Regulation during Development, Homeostasis and Alzheimer's Disease
Tags: 2021, Alzheimer’s disease, Alzheimer’, Casali BT, Cells, Department of Pharmaceutical Sciences, Inflammation, journalArticle, May 2021 List, Microglia, NEOMED College of Pharmacy, NEOMED College of Pharmacy Postdoc, NEOMED Postdoc Publications, Neurodegenerative Diseases, Neuroinflammation, Reed-Geaghan EG, s disease, TREM2
MicroRNA-602 and microRNA-608 regulate sonic hedgehog expression via target sites in the coding region in human chondrocytes.
Tags: 2015, Academic Medical Centers, Aged, Akhtar Nahid, Analysis of Variance, Animal, Animals, Anterior Cruciate Ligament/surgery, Arthritis & rheumatology (Hoboken, N.J.), Blotting, Cells, Chondrocytes – Physiology, Chondrocytes/drug effects/*metabolism/pathology, Cultured, Department of Anatomy & Neurobiology, Disease Models, Female, Funding Source, Gene Expression Regulation/genetics/*physiology, Haqqi Tariq M, Hedgehog Proteins/genetics/*metabolism, HEK293 Cells, Human, Humans, Immunohistochemistry, In Vitro Techniques, Interleukin-1beta/pharmacology, Knee/etiology/*metabolism/pathology, Makki Mohammad S, Male, Matrix Metalloproteinase 13/metabolism, MicroRNAs/genetics/*metabolism, Middle Age, Middle Aged, NEOMED College of Medicine, Ohio, Open Reading Frames/genetics/*physiology, Osteoarthritis, Osteoarthritis – Epidemiology, Osteoarthritis – Physiopathology, Polymerase Chain Reaction, Rabbits, Signal Transduction/genetics/physiology, T-Tests, Transfection, Up-Regulation/drug effects/genetics/physiology, Western
MicroRNA-9 promotion of interleukin-6 expression by inhibiting monocyte chemoattractant protein-induced protein 1 expression in interleukin-1beta-stimulated human chondrocytes.
Tags: 2015, Academic Medical Centers, Aged, Arthritis & rheumatology (Hoboken, N.J.), Articular/drug effects/*metabolism, Cartilage, Cells, Chondrocytes – Physiology, Chondrocytes/drug effects/*metabolism, Cultured, Department of Anatomy & Neurobiology, Enzyme-Linked Immunosorbent Assay, Funding Source, Gene Knockdown Techniques, Haqqi Tariq M, Haseeb Abdul, Hip/*genetics/metabolism, Human, Humans, Immunoblotting – Utilization, Immunoprecipitation, Interleukin-1beta/pharmacology, Interleukin-6/*genetics/metabolism, Interleukins – Physiology, Makki Mohammad S, Messenger/drug effects/*metabolism, MicroRNAs/drug effects/*genetics/metabolism, Middle Aged, NEOMED College of Medicine, Ohio, Osteoarthritis, Osteoarthritis – Complications, Osteoarthritis – Physiopathology, Reverse Transcriptase Polymerase Chain Reaction, Ribonucleases/drug effects/*genetics/metabolism, RNA, T-Tests, Transcription Factors/drug effects/*genetics/metabolism
Mitochondrial oxidative stress corrupts coronary collateral growth by activating adenosine monophosphate activated kinase-alpha signaling.
Tags: 2013, AMP-Activated Protein Kinases/*metabolism, Animal, Animals, Arteriosclerosis, thrombosis, and vascular biology, Body Weight/physiology, Cells, Chen Chwen-Lih, Chen Yeong-Renn, Chilian William M, Collateral Circulation, Coronary Circulation, Coronary Vessels/cytology/*enzymology, Cultured, Department of Integrative Medical Sciences, Disease Models, Dyck Jason R B, Endothelial Cells/cytology/*enzymology, Enrick Molly, Hardwick James P, Humans, Inbred WKY, Ischemia/metabolism/pathology, Kolz Christopher, Mitochondria, Mitochondria/drug effects/*metabolism, Myocardium/enzymology/pathology, NEOMED College of Medicine, Oxidative Stress/*physiology, Pung Yuh Fen, Rats, reactive oxygen species, Rotenone/pharmacology, Sam Wai Johnn, Signal Transduction/*physiology, Stevanov Kelly, Thakker Prashanth, TOR Serine-Threonine Kinases/metabolism, Uncoupling Agents/pharmacology, Yin Liya
Monoamine-activated alpha 2-macroglobulin inhibits choline acetyltransferase of embryonic basal forebrain neurons and reversal of the inhibition by NGF and BDNF but not NT-3.
Tags: 1994, alpha-Macroglobulins/antagonists & inhibitors/*pharmacology, Animals, Biogenic Monoamines/*pharmacology, Brain-Derived Neurotrophic Factor, Cells, Choline O-Acetyltransferase/*antagonists & inhibitors, Cultured, Humans, Journal of neuroscience research, Koo P H, Liebl D J, Nerve Growth Factors/*pharmacology, Nerve Tissue Proteins/pharmacology, Neurons/drug effects/*metabolism, Neurotrophin 3, Prosencephalon/*cytology, Rats
MORPHOMETRIC ANALYSIS OF COATED VESICLES IN DEVELOPING RAT MUSCLE-SPINDLES
Multiple signals induce endoplasmic reticulum stress in both primary and immortalized chondrocytes resulting in loss of differentiation, impaired cell growth, and apoptosis.
Tags: 2005, Animals, Annexin A5/metabolism, Anti-Bacterial Agents/metabolism, Apoptosis/*physiology, Biomarkers, Carlson Sara G, Caspase 12, Caspases/metabolism, CCAAT-Enhancer-Binding Proteins/metabolism, Cell Differentiation/*physiology, Cells, Chondrocytes/cytology/*physiology, Collagen Type II/metabolism, Cultured, Department of Anatomy & Neurobiology, DNA Fragmentation, Endoplasmic Reticulum/*metabolism, Extracellular Matrix/metabolism, Gene Expression Regulation, Glucose/metabolism, Horton Walter E Jr, McBurney Denise, NEOMED College of Medicine, Proliferating Cell Nuclear Antigen/metabolism, Rats, Signal Transduction/*physiology, Thapsigargin/metabolism, The Journal of biological chemistry, Transcription Factor CHOP, Transcription Factors/metabolism, Tunicamycin/metabolism, Yang Ling
Myocardial CXCR4 expression is required for mesenchymal stem cell mediated repair following acute myocardial infarction.
Tags: 2012, Agarwal U, Animal Studies, Apoptosis – Physiology, Cardiovascular System Physiology, Cell Movement – Physiology, Cell Physiology, Cell Surface, Cell Surface – Metabolism, Cells, Circulation, Coronary Circulation – Physiology, Cytokines – Metabolism, Department of Integrative Medical Sciences, Dong F, Finan A, Gene Expression – Physiology, Harvey J, Mice, myocardial infarction, Myocardial Infarction – Pathology, Myocardial Infarction – Therapy, Myocardium, NEOMED College of Medicine, Penn M S, Proteins, Receptors, Stem Cells – Metabolism, Stem Cells – Transplantation, Weber K
Neonatal activation of the nuclear receptor CAR results in epigenetic memory and permanent change of drug metabolism in mouse liver
Tags: 2012, bilirubin, Cells, Chen W D, clearance, coactivator, constitutive androstane receptor, developmental plasticity, Disease, Dong B N, Fu X H, Gastroenterology & Hepatology, Hepatology, Huang W D, human health, induction, Journal Article or Conference Abstract Publication, Mice, Moore D D, Shiah S, Wang Y D, x-receptor
Neutrophil elastase downmodulates native G-CSFR expression and granulocyte-macrophage colony formation
Tags: 2010, Ai J, Avalos B R, bone-marrow, Cells, Copelan A, cyclic neutropenia, Druhan L J, Immunology, Journal Article, Journal of Inflammation-London, Kindwall-Keller T L, leukocyte elastase, Loveland M, Massullo P R, mobilization, myeloid-leukemia, Piper M G, progenitor, quantum proteolysis, severe congenital neutropenia, signal-transduction, stem cell, stimulating-factor-receptor
Nrf2/ARE pathway attenuates oxidative and apoptotic response in human osteoarthritis chondrocytes by activating ERK1/2/ELK1-P70S6K-P90RSK signaling axis.
Tags: *Apoptosis, *ERK1/2, *Nrf2, *OSTEOARTHRITIS, *Redox, 2018, 70-kDa/metabolism, 90-kDa/metabolism, Ahmad Imran, Carboxylic Ester Hydrolases/metabolism, Caspases/metabolism, Cells, Chondrocytes/*physiology, Cultured, ets-Domain Protein Elk-1/metabolism, Free radical biology & medicine, Haqqi Tariq M, Humans, Interleukin-1beta/immunology, Khan Nazir M, MAP Kinase Signaling System, NF-E2-Related Factor 2/genetics/*metabolism, Osteoarthritis/*metabolism, Oxidative Stress, Ribosomal Protein S6 Kinases, Up-Regulation
Optimal reactive oxygen species concentration and p38 MAP kinase are required for coronary collateral growth.
Tags: *Collateral Circulation/drug effects, *Coronary Circulation/drug effects, *MAP Kinase Signaling System/drug effects, 2007, Acetophenones/pharmacology, American journal of physiology. Heart and circulatory physiology, Animal, Animals, Blood Flow Velocity, Cells, Chilian William M, Coronary Vessels/surgery, Cultured, Department of Integrative Medical Sciences, Disease Models, Ditiocarb/pharmacology, Endothelial Cells/drug effects/enzymology/*metabolism, Enzyme Inhibitors/pharmacology, Humans, Imidazoles/pharmacology, Inbred WKY, Kolz Christopher, Ligation, Male, Myocardial Reperfusion Injury/enzymology/metabolism/*physiopathology, NADPH Oxidases/antagonists & inhibitors/metabolism, NEOMED College of Medicine, Neovascularization, Onium Compounds/pharmacology, Oxygenases/antagonists & inhibitors/metabolism, p38 Mitogen-Activated Protein Kinases/antagonists & inhibitors/*metabolism, Physiologic, Potter Barry, Pyridines/pharmacology, Rats, Reactive Oxygen Species/*metabolism, Reed Ryan, Rocic Petra, Superoxide Dismutase/antagonists & inhibitors/metabolism, Vascular Endothelial Growth Factor A/metabolism
Orphan nuclear receptor oestrogen-related receptor gamma (ERRgamma) plays a key role in hepatic cannabinoid receptor type 1-mediated induction of CYP7A1 gene expression.
Tags: 2015, Animals, bile acid, Bile Acids and Salts/metabolism, Cannabinoid, cannabinoid receptors, CB1/agonists/genetics/*metabolism, Cells, Chiang John Y L, Choi Hueng-Sik, Cholesterol 7-alpha-Hydroxylase/*biosynthesis/genetics, cholesterol 7alpha-hydroxylase (CYP7A1), Cultured, Cytoplasmic and Nuclear/metabolism, Department of Integrative Medical Sciences, Drug Inverse Agonism, Estrogen/genetics/*metabolism, Ethanol/pharmacology, Gene Expression, Genetic, Glycerides/pharmacology, GSK5182, HEK293 Cells, Hepatocytes/metabolism, Humans, Inbred C57BL, Jeong Won-Il, Kim Don-Kyu, Kim Seong Heon, Knockout, Lee Chul-Ho, Lee In-Kyu, Lee Ji-Min, Liver/*metabolism, Mice, NEOMED College of Medicine, oestrogen-related receptor gamma (ERRgamma), orphan nuclear receptor, Park Seung Bum, Promoter Regions, Rats, Receptor, Receptors, small heterodimer partner (SHP), Sprague-Dawley, The Biochemical journal, Transcription, Zhang Yaochen
Osteoactivin inhibition of osteoclastogenesis is mediated through CD44-ERK signaling.
Tags: *MAP Kinase Signaling System, *Signal Transduction, 2016, Abdelmagid Samir M, Animals, Cell Differentiation, Cells, Cultured, Department of Anatomy & Neurobiology, Experimental & molecular medicine, Eye Proteins/*metabolism, Geldenhuys Werner J, Hyaluronan Receptors/*metabolism, Inbred C57BL, Jaber Fatima A, Male, Mbimba Thomas S, Membrane Glycoproteins/*metabolism, Mice, Moussa Fouad M, NEOMED College of Medicine, Novak Kimberly, Osteoclasts/*cytology/metabolism, RANK Ligand/metabolism, Recombinant Proteins/metabolism, Safadi Fayez F, Sondag Gregory R, Yu Bing
Osteoblasts Subjected To Spaceflight And Simulated Space Shuttle Launch Conditions
Tags: 2003, acceleration, bone cells, bone-formation, Cell Biology, Cells, Developmental Biology, differentiation, Flight, gene-expression, growing rats, In Vitro Cellular & Developmental Biology-Animal, in-vitro, Journal Article or Conference Abstract Publication, Kacena M A, Landis W J, messenger-rna expression, microgravity, Todd P, vibration, Weightlessness
PARAVERTEBRALMASSES IN BLUE-TAILED MONITOR, VARANUS DORIANUS, INDICATIVE OF SOFT-TISSUE INFECTION WITH ASSOCIATED OSTEOMYELITIS
Tags: 2014, Bone, Bone disease, Cells, classification, deformans pagets-disease, Journal Article, Journal of Zoo and Wildlife Medicine, lizard, mass, of-rheumatology criteria, Osteoarthritis, Osteomyelitis, Paget's disease, Rothschild B M, Spondyloarthropathy, Varanus dorianus, Vertebrae, Veterinary Sciences, virus