Browse Items (40 total)
- Tags: Blotting
Obesity-associated decrease in growth hormone-releasing hormone gene expression: a mechanism for reduced growth hormone mRNA levels in genetically obese Zucker rats.
Tags: *Gene Expression, 1993, Ahmad I, Animals, Blotting, Downs T R, Finkelstein J A, Frohman L A, Growth Hormone-Releasing Hormone/*genetics, Growth Hormone/blood/*genetics/metabolism, Male, Messenger/*metabolism, Neuroendocrinology, Northern, Obesity/*metabolism, Pituitary Gland/metabolism, Rats, RNA, Zucker
Developmental changes in levels of growth hormone mRNA in Zucker rats.
Tags: 1990, Aging/*metabolism, Ahmad I, Animals, Blotting, Carrillo A J, Finkelstein J A, Glyceraldehyde-3-Phosphate Dehydrogenases/genetics, Growth Hormone/blood/*genetics, Immunoblotting, Journal of cellular biochemistry, Male, Messenger/*metabolism, Northern, Obesity/*genetics, Prolactin/genetics, Rats, RNA, Steggles A W, Zucker
In situ hybridization study of obesity-associated alteration in growth hormone mRNA levels.
Tags: *Gene Expression Regulation, 1992, Ahmad I, Animals, Autoradiography, Blotting, Finkelstein J A, Genetic, Growth Hormone/*genetics/metabolism, International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, Male, Messenger/*analysis, Northern, Nucleic Acid Hybridization, Obesity/*etiology/physiopathology, Pituitary Gland/*chemistry/metabolism, Rats, RNA, Steggles A W, Transcription, Zucker
MicroRNA-602 and microRNA-608 regulate sonic hedgehog expression via target sites in the coding region in human chondrocytes.
Tags: 2015, Academic Medical Centers, Aged, Akhtar Nahid, Analysis of Variance, Animal, Animals, Anterior Cruciate Ligament/surgery, Arthritis & rheumatology (Hoboken, N.J.), Blotting, Cells, Chondrocytes – Physiology, Chondrocytes/drug effects/*metabolism/pathology, Cultured, Department of Anatomy & Neurobiology, Disease Models, Female, Funding Source, Gene Expression Regulation/genetics/*physiology, Haqqi Tariq M, Hedgehog Proteins/genetics/*metabolism, HEK293 Cells, Human, Humans, Immunohistochemistry, In Vitro Techniques, Interleukin-1beta/pharmacology, Knee/etiology/*metabolism/pathology, Makki Mohammad S, Male, Matrix Metalloproteinase 13/metabolism, MicroRNAs/genetics/*metabolism, Middle Age, Middle Aged, NEOMED College of Medicine, Ohio, Open Reading Frames/genetics/*physiology, Osteoarthritis, Osteoarthritis – Epidemiology, Osteoarthritis – Physiopathology, Polymerase Chain Reaction, Rabbits, Signal Transduction/genetics/physiology, T-Tests, Transfection, Up-Regulation/drug effects/genetics/physiology, Western
Fetal lung epithelial ion channels relocate in the cell membrane during late gestation.
Tags: 2011, Anatomical record (Hoboken, N.J. : 2007), Animals, Beard LaMonta L, Blotting, Caveolin 1/*metabolism, Cell Membrane/*metabolism, Cl transport, Cystic Fibrosis Transmembrane Conductance Regulator/*metabolism, distal lung fluid absorption, Epithelial Sodium Channels/*metabolism, Epithelium/embryology/*metabolism, Female, fetal lung development, Fetus/*metabolism, Folkesson Hans G, Gestational Age, Guinea Pigs, Hu Yang, IL-1beta, Immunoprecipitation, Interleukin-1beta/metabolism, Ion Channels/metabolism, Li Tianbo, Lung/embryology/*metabolism, Na transport, Western
Pomegranate Bioactive Constituents Suppress Cell Proliferation and Induce Apoptosis in an Experimental Model of Hepatocellular Carcinoma: Role of Wnt/β-Catenin Signaling Pathway.
Tags: 2013, Animal Studies, Apoptosis, Bhatia Deepak, Bishayee Anupam, Blotting, Carcinoma, Darvesh Altaf S, Department of Pharmaceutical Sciences, Evidence-based Complementary & Alternative Medicine (eCAM), Experimental Studies, Gene Expression, Hepatocellular, Immunohistochemistry, In Vivo Studies, Mandal Animesh, NEOMED College of Pharmacy, One-Way Analysis of Variance, Pomegranate, Post Hoc Analysis, Protocols, Rats, Samtani Karishma A, STRUCTURAL equation modeling, Thoppil Roslin J, Western
Pomegranate-mediated chemoprevention of experimental hepatocarcinogenesis involves Nrf2-regulated antioxidant mechanisms.
Tags: *Phytotherapy, 2011, Alkylating Agents/toxicity, Animals, Antioxidants/*therapeutic use, Bhatia Deepak, Bishayee Anupam, Blotting, Carcinogenesis, Carcinoma, Darvesh Altaf S, Department of Pharmaceutical Sciences, Diethylnitrosamine/toxicity, Experimental/chemically induced/*drug therapy/metabolism, GA-Binding Protein Transcription Factor/*metabolism, gamma-Glutamyltransferase/metabolism, Hepatocellular/chemically induced/*drug therapy/metabolism, Immunoenzyme Techniques, Lansky Ephraim P, Lipid Peroxidation/drug effects, Liver Neoplasms, Male, NEOMED College of Pharmacy, Nevo Eviatar, Oxidative Stress, Plant Extracts/*therapeutic use, Punicaceae/*chemistry, Rats, Sprague-Dawley, Thoppil Roslin J, Western
Markers associated with testosterone enhancement of methamphetamine-induced striatal dopaminergic neurotoxicity.
Tags: 2012, Animals, Biomarkers/metabolism, Blotting, Body Temperature/drug effects, Body Weight/drug effects, Buletko A Blake, Corpus Striatum/*drug effects/metabolism, Darvesh Altaf S, Department of Pharmaceutical Sciences, Dluzen Dean E, Dopamine Plasma Membrane Transport Proteins/metabolism, Dopamine/*metabolism, Drug Synergism, Geldenhuys Werner J, HSP70 Heat-Shock Proteins/metabolism, Inbred Strains, Male, McDermott Janet L, Methamphetamine/*toxicity, Mice, NEOMED College of Pharmacy, Neurotoxicity Syndromes/*etiology/metabolism, Neurotoxicology and teratology, Oxidative Stress/drug effects, Testosterone Propionate/*pharmacology, Vesicular Monoamine Transport Proteins/metabolism, Western
The Detrimental Role Played by Lipocalin-2 in Alcoholic Fatty Liver in Mice.
Tags: 2016, Alcoholic/*metabolism, Animal, Animals, Blotting, Cai Yan, Department of Pharmaceutical Sciences, Disease Models, Fatty Liver, Gao Bin, Hu Xudong, Humans, Inbred C57BL, Jogasuria Alvin, Kim Chunki, Knockout, Lee Kwangwon, Lipocalin-2/*metabolism, Mice, NEOMED College of Pharmacy, Polymerase Chain Reaction, The American journal of pathology, Wang Jiayou, Western, Wu Jiashin, Xu Ming-Jiang, Yin Huquan, You Min
Identification of a new P450 subfamily, CYP4F1, expressed in rat hepatic tumors.
Tags: 1993, 2-Acetylaminofluorene, Aflatoxin B1, Amino Acid, Amino Acid Sequence, Animals, Antisense Elements (Genetics), Archives of biochemistry and biophysics, Base Sequence, Blotting, Chen L, Clofibrate, Cytochrome P-450 Enzyme System/analysis/*genetics, Department of Integrative Medical Sciences, Hardwick J P, Humans, Liver Neoplasms/chemically induced/*enzymology/genetics, Male, Microsomes/enzymology, Molecular Sequence Data, Multigene Family, NEOMED College of Medicine, Northern, Rats, Sequence Homology, Western
Genomic cloning, sequencing, and analysis of the hamster cholesterol 7 alpha-hydroxylase gene (CYP7).
Tags: 1993, Amino Acid, Amino Acid Sequence, Animals, Archives of biochemistry and biophysics, Base Sequence, Blotting, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics, Cloning, Crestani M, Cricetinae, Department of Integrative Medical Sciences, DNA/genetics/isolation & purification, Galli G, Genomic Library, Humans, Liver/enzymology, Mesocricetus/*genetics, Messenger/biosynthesis/metabolism, Molecular, Molecular Sequence Data, NEOMED College of Medicine, Northern, Poly A/biosynthesis/metabolism, Rats, Restriction Mapping, RNA, Sequence Homology, Southern
The isolation and characterization of the bovine cytochrome b5 gene, and a transcribed pseudogene.
Tags: *Pseudogenes, 1993, Amino Acid Sequence, Animals, Base Sequence, Blotting, Cattle/*genetics, Cristiano R J, Cytochromes b5/*genetics, DNA/genetics/isolation & purification, Exons, Gene Expression, Genetic, Genomic Library, Genomics, Giordano S J, Humans, Introns, Messenger/biosynthesis/metabolism, Molecular Sequence Data, Nucleic Acid, Nucleic Acid Conformation, Oligodeoxyribonucleotides, Rabbits, Restriction Mapping, Reticulocytes/metabolism, RNA, RNA Precursors/chemistry/metabolism, Sequence Homology, Southern, Steggles A W, Transcription
Resveratrol inhibition of varicella-zoster virus replication in vitro.
Tags: 2006, Antiviral Agents/*pharmacology, Antiviral research, Bailey Erin, Blotting, Booth Tristan, Cell Line, Docherty John J, Dose-Response Relationship, Drug, Faith Seth A, Fibroblasts/virology, Herpesvirus 3, Human/*drug effects/physiology, Humans, Immediate-Early Proteins/biosynthesis, Messenger/biosynthesis, Resveratrol, Reverse Transcriptase Polymerase Chain Reaction, RNA, Stilbenes/*pharmacology, Sweet Thomas J, Trans-Activators/biosynthesis, Viral Envelope Proteins/biosynthesis, Viral Plaque Assay, Viral/biosynthesis, Virus Attachment/drug effects, Virus Inactivation/drug effects, Virus Replication/*drug effects, Western
Differential expression of the mRNAs for the soluble and membrane-bound forms of rabbit cytochrome b5.
Tags: 1993, Agar Gel, Amino Acid Sequence, Animals, Base Sequence, Biochimica et biophysica acta, Blotting, Cell Membrane/metabolism, Cytochromes b5/*genetics, Cytosol/metabolism, DNA/genetics/isolation & purification, Electrophoresis, Exons, Giordano S J, Leukocytes/metabolism, Liver/*metabolism, Messenger/genetics/isolation & purification/*metabolism, Molecular Sequence Data, Oligodeoxyribonucleotides, Polymerase Chain Reaction/methods, Rabbits, Reticulocytes/metabolism, RNA, Southern, Steggles A W
The human cytochrome b5 gene and two of its pseudogenes are located on chromosomes 18q23, 14q31-32.1 and 20p11.2, respectively.
Tags: *Chromosomes, 1993, Animals, Bhatt M, Blotting, Cell Line, Chromosome Mapping, Cricetinae, Cytochromes b5/*genetics, DNA/analysis, Genetic/genetics, Giordano S J, Human, Human genetics, Humans, Hybrid Cells, In Situ Hybridization, Molecular Sequence Data, Overhauser J, Pair 14, Pair 18, Pair 20, Polymerase Chain Reaction, Pseudogenes/*genetics, Southern, Steggles A W, Translocation, Ward D C, Yoo M
Something completely different?
Tags: 1996, Animals, Blotting, Brain/*enzymology, Chen L, Cloning, Complementary, Cytochrome P-450 Enzyme System/*genetics/isolation & purification, Department of Integrative Medical Sciences, DNA, Hardwick J P, Human & experimental toxicology, Kidney/enzymology, Liver/enzymology, Molecular, NEOMED College of Medicine, Northern, Rats
Primary cilia regulates the directional migration and barrier integrity of endothelial cells through the modulation of hsp27 dependent actin cytoskeletal organization.
Tags: *Cell Movement, 2012, AbouAlaiwi Wissam A, Actin Cytoskeleton/*metabolism, Adapala Ravi K, Animals, Blotting, Bursley Chris, Capillary Permeability/*physiology, Cell Adhesion, Cilia/metabolism, Department of Integrative Medical Sciences, Endothelial Cells/cytology/*metabolism, Fluorescent Antibody Technique, Focal Adhesions/metabolism, Geldenhuys Werner J, HSP27 Heat-Shock Proteins/*metabolism, Jones Thomas J, Journal of cellular physiology, Mice, Nauli Surya M, NEOMED College of Medicine, Polycystic Kidney Diseases/physiopathology, Signal Transduction/physiology, Thodeti Charles K, Transgenic, Western
Activation of metabotropic glutamate receptor 1 dimers requires glutamate binding in both subunits.
Tags: 2005, Blotting, Calcium Channels/drug effects/metabolism, Department of Integrative Medical Sciences, DNA/biosynthesis/genetics, Dose-Response Relationship, Drug, Fluorescent Antibody Technique, Genes, Glutamic Acid/*metabolism, Humans, Kammermeier Paul J, Membrane Potentials/drug effects, Metabotropic Glutamate/genetics/*metabolism, myc/genetics, NEOMED College of Medicine, Patch-Clamp Techniques, Plasmids/genetics, Receptors, Signal Transduction/drug effects, Superior Cervical Ganglion/cytology/drug effects/metabolism, Sympathetic Nervous System/cytology/drug effects/metabolism, The Journal of pharmacology and experimental therapeutics, Western, Yun June
Altered Neuroinflammation and Behavior after Traumatic Brain Injury in a Mouse Model of Alzheimer's Disease.
Tags: 2016, Alzheimer Disease/etiology/*metabolism/pathology, Alzheimer's disease, Amyloid beta-Peptides/*metabolism, Animal, Animal/physiology, Animals, Behavior, Bemiller Shane M, Bhaskar Kiran, Blotting, Brain Injuries, Brain/*metabolism/pathology, Crish Samuel, Department of Pharmaceutical Sciences, Disease Models, Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Humans, Immunohistochemistry, Inbred C57BL, Inflammation/*metabolism/pathology, Journal of neurotrauma, Kokiko-Cochran Olga N, Lamb Bruce T, Lee Sungho, Lee Yu-Shang, macrophage, Mice, NEOMED College of Pharmacy, Neuroinflammation, Ransohoff Lena, Ransohoff Richard M, Saber Maha, Sikora Matt, Teknipp Ryan, Transgenic, Traumatic brain injury, Traumatic/complications/*metabolism/*pathology, Veenstra Mike, Western, Wilson Gina, Xu Guixiang
Rifampicin induction of CYP3A4 requires pregnane X receptor cross talk with hepatocyte nuclear factor 4alpha and coactivators, and suppression of small heterodimer partner gene expression.
Tags: 2006, Antibiotics, Antitubercular/*pharmacology, Blotting, Cell Line, Chiang John Y L, Chromatin/metabolism, Cytochrome P-450 CYP3A, Cytochrome P-450 Enzyme System/*biosynthesis, Cytoplasmic and Nuclear/*biosynthesis/*drug effects/genetics, Department of Integrative Medical Sciences, Drug metabolism and disposition: the biological fate of chemicals, Electrophoretic Mobility Shift Assay, Enzyme Induction/drug effects, Glutathione Transferase/metabolism, Hepatocyte Nuclear Factor 4/genetics/*metabolism, Hepatocytes/drug effects/metabolism, Humans, Immunoprecipitation, Li Tiangang, Messenger/biosynthesis, NEOMED College of Medicine, Plasmids/genetics, Pregnane X Receptor, Receptor Cross-Talk/drug effects, Receptors, Reverse Transcriptase Polymerase Chain Reaction, Rifampin/*pharmacology, RNA, Steroid/*drug effects/genetics, Transfection, Tumor, Western
The expression of a catalytically active cholesterol 7 alpha-hydroxylase cytochrome P450 in Escherichia coli.
Tags: 1991, Amino Acid Sequence, Base Sequence, Blotting, Catalysis, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics, Cholesterol/metabolism, Chromatography, Codon, Department of Integrative Medical Sciences, DNA/genetics, Electrophoresis, Escherichia coli/*enzymology, Gene Expression, Li Y C, Liquid, Liver/enzymology, Microsomes, Molecular Sequence Data, NEOMED College of Medicine, Plasmids, Polyacrylamide Gel, Polymerase Chain Reaction, Substrate Specificity, The Journal of biological chemistry, Western
Chemopreventive doses of resveratrol do not produce cardiotoxicity in a rodent model of hepatocellular carcinoma.
Tags: *Chemoprevention, 2011, Analysis of Variance, Animal, Animal Studies, Animal/drug effects, Animals, Antioxidants, Behavior, Bishayee Anupam, Blotting, Booth Tristan D, Carcinoma, Cardiotoxicity, Cardiotoxins/*toxicity, Chemoprevention, Data Analysis Software, Department of Integrative Medical Sciences, Descriptive Statistics, Disease Models, Doppler, Dose-Response Relationship, Drug, Echocardiography, Feeding Behavior/drug effects, Female, Fisher's Exact Test, Funding Source, Heart – Drug Effects, Heart/drug effects/physiopathology, Hepatocellular – Prevention and Control, Hepatocellular/*drug therapy/pathology/physiopathology, Hepatocytes/drug effects/pathology, Hodnichak Cheryl M, Humans, Investigational new drugs, Liver Neoplasms/*drug therapy/pathology/physiopathology, Liver/drug effects/pathology/physiopathology, Luther Daniel J, Meszaros J Gary, NEOMED College of Medicine, Ohanyan Vahagn, Polyphenols – Therapeutic Use, Rats, Resveratrol, Shamhart Patricia E, Sisakian Hamayak, Sprague-Dawley, Stilbenes/*therapeutic use, Systole/drug effects, Western
Histone Deacetylase Inhibitor Vorinostat (SAHA) Suppresses IL-1beta-Induced Matrix Metallopeptidase-13 Expression by Inhibiting IL-6 in Osteoarthritis Chondrocyte.
Tags: 2016, Aged, Articular/drug effects/metabolism, Blotting, Cartilage, Chondrocytes/drug effects, Collagen Type II/drug effects/metabolism, Department of Anatomy & Neurobiology, Down-Regulation/drug effects, Female, Gene Expression Regulation/*drug effects, Haqqi Tariq M, Histone Deacetylase Inhibitors/*pharmacology, Humans, Hydroxamic Acids/*pharmacology, Interleukin-1beta/*antagonists & inhibitors/genetics/metabolism, Knee Joint/metabolism, Makki Mohammad Shahidul, Male, Matrix Metalloproteinase 13/*drug effects/metabolism, Middle Aged, NEOMED College of Medicine, Osteoarthritis/*drug therapy, Proteoglycans/metabolism, The American journal of pathology, Tumor Necrosis Factor-alpha/drug effects/metabolism, Vorinostat, Western
Synthesis of radioactive single-stranded DNA probes using asymmetrical PCR and oligonucleotide random priming.
Tags: *DNA, *Oligonucleotides, *Phosphorus Radioisotopes, 1999, Animals, BioTechniques, Blotting, Cercopithecus aethiops, Deoxyribonuclease EcoRI, DNA, DNA Probes/*chemical synthesis, Genetic, Herpesvirus 1, Human/genetics, Isotope Labeling, Mao H, Messenger/analysis, Northern, Nucleic Acid Denaturation, Polymerase Chain Reaction/*methods, RNA, Rosenthal K S, Single-Stranded, Templates, Vero Cells, Viral/analysis
The presence of extracellular matrix alters the chondrocyte response to endoplasmic reticulum stress.
Tags: *Stress, 2011, Animals, Apoptosis/drug effects, Articular/cytology, Blotting, Cartilage, Cattle, Cells, Chondrocytes/cytology/drug effects/*metabolism, Cultured, Department of Anatomy & Neurobiology, DNA-Binding Proteins/genetics/metabolism, Dose-Response Relationship, Drug, Endoplasmic Reticulum/*metabolism, Extracellular Matrix/*metabolism, Glucose/pharmacology, Heat-Shock Proteins/genetics/metabolism, Horton Walter E Jr, Journal of cellular biochemistry, McBurney Denise L, NEOMED College of Medicine, Nugent Ashleigh E, Physiological, Proto-Oncogene Proteins c-bcl-2/genetics/metabolism, Reverse Transcriptase Polymerase Chain Reaction, Thapsigargin/pharmacology, Time Factors, Transcription Factors/genetics/metabolism, Tunicamycin/pharmacology, Western
Estrogen receptor-alpha and neural circuits to the spinal cord during pregnancy.
Tags: 2002, Afferent/*metabolism, Animal/*physiology, Animals, Autonomic/anatomy & histology/metabolism, Blotting, Department of Anatomy & Neurobiology, Estrogen Receptor alpha, Estrogen/*biosynthesis, Estrogens/*physiology, Female, Ganglia, Hafemeister J, Immunohistochemistry, Journal of neuroscience research, NEOMED College of Medicine, Neurons, Papka R E, Parturition/physiology, Pregnancy, Proto-Oncogene Proteins c-fos/*biosynthesis, Puder B A, Rats, Receptors, Sensory/anatomy & histology/metabolism, Spinal Cord/anatomy & histology/metabolism, Sprague-Dawley, Storey-Workley M, Time Factors, Usip S, Uterus/innervation, Western
P2X receptors in the rat uterine cervix, lumbosacral dorsal root ganglia, and spinal cord during pregnancy.
Tags: 2005, Animals, Blotting, Cell and tissue research, Cervix Uteri/*metabolism, Estrogen Receptor alpha/metabolism, Female, Frozen Sections, Ganglia, Hafemeister Jen, Immunohistochemistry, Lumbosacral Region, Papka Raymond E, Pregnancy, Purinergic P2/*metabolism, Purinergic P2X, Rats, Receptors, Spinal Cord/cytology/*metabolism, Spinal/cytology/*metabolism, Sprague-Dawley, Storey-Workley Megan, Western
Activation and circuitry of uterine-cervix-related neurons in the lumbosacral dorsal root ganglia and spinal cord at parturition.
Tags: 2005, Analysis of Variance, Animals, Blotting, Cell Count/methods, Cervix Uteri/*cytology, Cyclic AMP Response Element-Binding Protein/metabolism, Estrogen Receptor alpha/metabolism, Female, Ganglia, Gene Expression Regulation/physiology, Immunohistochemistry/methods, Journal of neuroscience research, Lumbosacral Region, Models, Nerve Net/cytology/*physiology, Neurological, Neurons/classification/*physiology, Oncogene Proteins v-fos/metabolism, Papka R E, Parturition/*physiology, Pregnancy, Puder B A, Rats, Spinal Cord/*cytology, Spinal/*cytology, Sprague-Dawley, Stilbamidines/metabolism, Time Factors, Western/methods
Apocynum Tablet Protects against Cardiac Hypertrophy via Inhibiting AKT and ERK1/2 Phosphorylation after Pressure Overload.
Tags: 2014, Animal Studies, Aorta – Physiopathology, Blotting, Descriptive Statistics, Echocardiography, Evidence-based Complementary & Alternative Medicine (eCAM), Funding Source, Gene Expression Profiling, Gong Kaizheng, Guo Liheng, Heart Diseases – Prevention and Control, Hypertrophy – Prevention and Control, In Vivo Studies, Liu Qin, Mice, One-Way Analysis of Variance, Phosphorylation – Drug Effects, Plant Extracts – Therapeutic Use, Post Hoc Analysis, Protein Kinases – Antagonists and Inhibitors, Qi Jianyong, Signal Transduction, Staining and Labeling, T-Tests, Vasoconstriction, Wang Lei, Western, Wu Jiashin, Yu Juan, Zhang Minzhou, Zhou Miao
Salvianolate reduces murine myocardial ischemia and reperfusion injury via ERK1/2 signaling pathways in vivo.
Tags: *MAP Kinase Signaling System/drug effects, 2017, Animal Studies, Animals, Blotting, Cardiotonic Agents/pharmacology/therapeutic use, Chinese journal of integrative medicine, Chinese medicine, Descriptive Statistics, extracellular signal-regulated kinase 1/2, Flavonoids/pharmacology, Guo Liheng, Heart Ventricle, Heart Ventricles/drug effects/pathology, Huang Dong-Hui, Huang Hai-Ding, Huang Xin, In Vivo Studies, Inbred C57BL, ischemia and reperfusion injury, Left, Male, Mice, Mitogen-Activated Protein Kinase 1/*metabolism, Mitogen-Activated Protein Kinase 3/*metabolism, Molecular Structure, Myocardial Ischemia – Drug Therapy, Myocardial Reperfusion Injury – Drug Therapy, Myocardial Reperfusion Injury/*drug therapy/enzymology/pathology, Organ Size/drug effects, P-Value, Phosphorylation, Phosphorylation/drug effects, Plant Extracts – Administration and Dosage, Plant Extracts/chemistry/pharmacology/*therapeutic use, protein kinase B, Protein Kinase Inhibitors – Administration and Dosage, Protein Kinase Inhibitors/pharmacology, Protein Kinases – Analysis, Protein Kinases – Drug Effects, Qi Jianyong, salvianolate, Signal Transduction, Staining and Labeling, Wang Lei, Western, Wu Jiashin, Yu Juan, Zhang Minzhou, Zhou Miao
A class of genes in the HER2 regulon that is poised for transcription in breast cancer cell lines and expressed in human breast tumors.
Tags: *Gene Expression Profiling, *Gene Expression Regulation, 2015, Blotting, Breast Neoplasms/genetics/pathology, Cell Line, Char Jessica E, Chen Xin, ErbB-2/*genetics/metabolism, Franke Anna-Clara, Gene Regulatory Networks, Homeodomain Proteins/genetics/metabolism, Humans, Jia Zhenyu, Jones Frank E, McClelland Michael, MCF-7 Cells, Men Bozhao, Mercola Dan, Nanog Homeobox Protein, Neoplastic, Neoplastic Stem Cells/metabolism, Octamer Transcription Factor-3/genetics/metabolism, Oncotarget, Rahmatpanah Farah B, Receptor, Regulon/*genetics, Reverse Transcriptase Polymerase Chain Reaction, RNA Polymerase II/metabolism, SOXB1 Transcription Factors/genetics/metabolism, Tumor, Tumor Microenvironment/genetics, Western
Impact of type 1 diabetes on cardiac fibroblast activation: enhanced cell cycle progression and reduced myofibroblast content in diabetic myocardium.
Tags: 2009, American journal of physiology. Endocrinology and metabolism, Animals, Blood Glucose/metabolism, Blotting, Body Weight/physiology, Cell Cycle Proteins/biosynthesis, Cell Cycle/*physiology, Cell Differentiation/physiology, Cell Proliferation, Cell Separation, Department of Integrative Medical Sciences, Diabetes Mellitus, Echocardiography, Experimental/pathology, Fibroblasts/*physiology, Hodson Ben R, Koshy John C, Luther Daniel J, Male, Meszaros J Gary, Microarray Analysis, Myocardium/cytology/*pathology, Myofibroblasts/*physiology, NEOMED College of Medicine, Ohanyan Vahagn, Phenotype, Rats, RNA/biosynthesis/isolation & purification, Shamhart Patricia E, Signal Transduction/physiology, Sprague-Dawley, Type 1/diagnostic imaging/*pathology, Western
Induction of ethanol dependence increases signal peptidase mRNA levels in rat brain.
Tags: *Membrane Proteins, *Serine Endopeptidases, 1994, Alcoholism/*enzymology, Amino Acid, Amino Acid Sequence, Animals, Base Sequence, Blotting, Brain/*enzymology, Complementary, DNA, Endopeptidases/*biosynthesis/chemistry/genetics, Ethanol/*pharmacology, Jacquet R, Male, Messenger/genetics/metabolism, Molecular and cellular biochemistry, Molecular Sequence Data, Northern, Nucleic Acid, Rats, RNA, Sequence Homology, Signs S A, Sprague-Dawley, Substance Withdrawal Syndrome/enzymology
Serotonergic involvement in the regulation of prolactin and vasoactive intestinal peptide mRNA expression in the rat anterior pituitary.
Tags: 1994, 5-Hydroxytryptophan/pharmacology, alpha-Methyltyrosine, Animals, Anterior/*chemistry/drug effects/metabolism, Blotting, Bromocriptine/pharmacology, Carrillo A J, Gene Expression Regulation/drug effects/physiology, Genetic, Haloperidol/pharmacology, Ketanserin/pharmacology, Liu B, Male, Messenger/*analysis/genetics, Methiothepin/pharmacology, Methoxydimethyltryptamines/pharmacology, Methyltyrosines/pharmacology, Molecular and cellular endocrinology, Northern, Pituitary Gland, Prolactin/analysis/*genetics/metabolism, Quipazine/pharmacology, Rats, RNA, Serotonin/*physiology, Signs S A, Sprague-Dawley, Time Factors, Transcription, Vasoactive Intestinal Peptide/analysis/*genetics/metabolism, Wolford J
Phosphatidylinositide 3-kinase regulates angiotensin II-induced cytosolic phospholipase A2 activity and growth in vascular smooth muscle cells.
Tags: 2002, Angiotensin II/*metabolism, Animals, Arachidonic Acid/metabolism, Arachidonic Acids/pharmacology, Archives of biochemistry and biophysics, Blotting, Cells, Chromones/pharmacology, Cultured, Enzyme Inhibitors/pharmacology, Flavonoids/pharmacology, Freeman Ernest J, Group IV Phospholipases A2, Male, Mitogen-Activated Protein Kinases/metabolism, Morpholines/pharmacology, Muscle, Phosphatidylinositol 3-Kinases/*physiology, Phospholipases A/*metabolism, Phospholipases A2, Phosphorylation, Rats, Silfani Tonous N, Smooth, Sprague-Dawley, Vascular/drug effects/*growth & development, Western
Ambient GABA-activated tonic inhibition sharpens auditory coincidence detection via a depolarizing shunting mechanism.
Tags: 2011, Animals, Auditory Pathways/*physiology, Blotting, Chick Embryo, Department of Anatomy & Neurobiology, Dinh Emilie Hoang, Electric Stimulation, GABA-A/*physiology, gamma-Aminobutyric Acid/*physiology, Inhibitory Postsynaptic Potentials, Lu Yong, Membrane Potentials/physiology, NEOMED College of Medicine, Neural Inhibition/*physiology, Neurons/*physiology, Patch-Clamp Techniques, Receptors, Shi Wei, Tang Zheng-Quan, The Journal of neuroscience : the official journal of the Society for Neuroscience, Western
Black currant anthocyanins abrogate oxidative stress through Nrf2- mediated antioxidant mechanisms in a rat model of hepatocellular carcinoma.
Tags: *Phytotherapy, 2012, Alkylating Agents/toxicity, Animals, Anthocyanins/*therapeutic use, Antioxidants/therapeutic use, Barnes Kendra F, Bhatia Deepak, Bishayee Anupam, Blotting, Carcinoma, Current cancer drug targets, Darvesh Altaf S, Department of Pharmaceutical Sciences, Diet, Diethylnitrosamine/toxicity, Experimental/chemically induced/metabolism/*prevention & control, Glutathione Transferase, Haznagy-Radnai Erzsebet, Hepatocellular/chemically induced/metabolism/*prevention & control, Hohmann Judit, Immunoenzyme Techniques, Lipid Peroxidation/drug effects, Liver Neoplasms, Male, Messenger/genetics, NEOMED College of Pharmacy, NF-E2-Related Factor 2/genetics/*metabolism, Nitric Oxide Synthase Type II/genetics/metabolism, Oxidative Stress/*drug effects, Rats, Real-Time Polymerase Chain Reaction, Reverse Transcriptase Polymerase Chain Reaction, Ribes/*chemistry, RNA, Signal Transduction, Sprague-Dawley, Thoppil Roslin J, Tyrosine/analogs & derivatives/metabolism, Western
The isolation and characterization of the soluble and membrane-bound porcine cytochrome b5 cDNAs.
Tags: 1997, Amino Acid Sequence, Animals, Base Sequence, Biochemical and biophysical research communications, Blotting, Complementary/blood/*chemistry/*isolation & purification, Cytochromes b5/blood/*chemistry/genetics/*isolation & purification, DNA, Male, Membrane Proteins/*chemistry/genetics/*isolation & purification, Molecular Sequence Data, Solubility, Southern, Steggles A W, Swine, Testis/enzymology, VanDerMark P K
Structure and functions of human oxysterol 7alpha-hydroxylase cDNAs and gene CYP7B1.
Tags: 1999, Animals, Base Sequence, Blotting, Cell Line, Chiang J Y, Chromosome Mapping, Cloning, Codon, Complementary/biosynthesis/*isolation & purification, Cytochrome P-450 Enzyme System/*genetics/metabolism, Cytochrome P450 Family 7, Department of Integrative Medical Sciences, DNA, Genetic, Genetic/genetics, Humans, Hydroxycholesterols/metabolism, Initiator, Javitt N B, Journal of lipid research, Luciferases/genetics, Martin K O, Mice, Molecular, Molecular Sequence Data, NEOMED College of Medicine, Northern, Nucleic Acid, Promoter Regions, Regulatory Sequences, Steroid Hydroxylases/*genetics/metabolism, Transcription, Transfection, Wu Z
Bcl-2 positively regulates Sox9-dependent chondrocyte gene expression by suppressing the MEK-ERK1/2 signaling pathway.
Tags: *Gene Expression Regulation, 2005, Adenoviridae/genetics, Animals, Apoptosis, beta-Galactosidase/metabolism, Blotting, Butadienes/pharmacology, Caspase Inhibitors, Cell Differentiation, Cell Line, Chondrocytes/*metabolism, Collagen Type II/metabolism, Department of Anatomy & Neurobiology, Down-Regulation, Enzyme Inhibitors/pharmacology, Fibroblasts/metabolism, Fluorescence, Genetic, High Mobility Group Proteins/*metabolism, Horton Walter E Jr, Lac Operon, Luciferases/metabolism, MAP Kinase Kinase Kinases/*metabolism, McBurney Denise, Messenger/metabolism, Microscopy, Mitogen-Activated Protein Kinase 1/*metabolism, Mitogen-Activated Protein Kinase 3/*metabolism, NEOMED College of Medicine, NF-kappa B/metabolism, Nitriles/pharmacology, Phenotype, Phosphorylation, Promoter Regions, Protein Kinase C-alpha, Protein Kinase C/antagonists & inhibitors, Proteoglycans/metabolism, Proto-Oncogene Proteins c-bcl-2/*metabolism, Rats, Reverse Transcriptase Polymerase Chain Reaction, RNA, Signal Transduction, Small Interfering/metabolism, SOX9 Transcription Factor, Sprague-Dawley, The Journal of biological chemistry, Time Factors, Transcription, Transcription Factors/*metabolism, Transfection, Western, Yagi Rieko