Browse Items (109 total)
- Tags: Animal
The ability of an HSV strain to initiate zosteriform spread correlates with its neuroinvasive disease potential.
Tags: 2002, Animal, Animals, Archives of virology, Disease Models, Docherty J J, Ganglia, Goel N, Herpes Simplex/*physiopathology/virology, Herpesvirus 1, Human/*pathogenicity, Inbred BALB C, Mao H, Mice, Rong Q, Rosenthal K S, Skin Diseases/*physiopathology/virology, Spinal/*virology, Time Factors, Virulence, Zimmerman D
A modification of the epidermal scarification model of herpes simplex virus infection to achieve a reproducible and uniform progression of disease.
Tags: *Herpesvirus 1, 2002, Animal, Animals, Disease Models, Disease Progression, Docherty John J, Female, Fu Ming Ming, Goel Neena, Herpes Simplex/pathology/physiopathology/*transmission, Human, Humans, Inbred BALB C, Journal of virological methods, Mice, Reproducibility of Results, Rosenthal Kenneth S, Skin/virology, Zimmerman Daniel H
The Physiologic Impact of Unilateral Recurrent Laryngeal Nerve (RLN) Lesion on Infant Oropharyngeal and Esophageal Performance.
Tags: 2015, Animal, Animals, Aspiration, Ballester Ashley, Biological, Deglutition, Deglutition – Physiology, Deglutition disorders, Deglutition Disorders – Etiology, Deglutition Disorders – Physiopathology, Deglutition Disorders/*etiology/physiopathology, Deglutition/*physiology, Department of Anatomy & Neurobiology, Disease Models, Dysphagia, Esophagus, Esophagus – Physiopathology, Esophagus/*physiopathology, Fraley Luke, German Rebecca Z, Gould François D H, Gross Andrew, Human, Infant, Lammers Andrew R, Laryngeal Nerves – Injuries, Laryngeal Nerves – Physiopathology, Models, NEOMED College of Medicine, Ohlemacher Jocelyn, Oropharynx – Physiopathology, Oropharynx/*physiopathology, Recurrent laryngeal nerve, Recurrent Laryngeal Nerve Injuries/*complications/physiopathology, Recurrent Laryngeal Nerve/*physiopathology, Swine
Postnatal developmental changes in the medial nucleus of the trapezoid body in a mouse model of auditory pathology.
Tags: *Disease Models, 2014, AHL, Animal, Animals, Auditory brainstem responses, Auditory Pathways/*growth & development/*pathology, Auditory system, DBA/2, Grimsley Calum A, Hearing Loss/*pathology, Inbred CBA, Inbred DBA, Mice, MNTB, Neuroscience letters, Newborn, Olivary Nucleus/*growth & development/*pathology, Organ Culture Techniques, Sivaramakrishnan Shobhana
LVC Timing in Infant Pig Swallowing and the Effect of Safe Swallowing.
Tags: *Animal model, *Aspiration, *Deglutition, *Deglutition disorders, *Dysphagia, *Infant, *Laryngeal vestibule closure, *Recurrent laryngeal nerve, 2018, Animal, Animal Population Groups, Animals, Aspiration – Etiology, Aspiration/*etiology, Biological, Deglutition – Physiology, Deglutition Disorders – Etiology, Deglutition Disorders/*etiology, Deglutition/*physiology, Department of Anatomy & Neurobiology, Disease Models, Dysphagia, German Rebecca, Gould Francois, Gross Andrew, Humans, Laryngeal Nerve Injuries/*complications, Laryngeal Nerves – Injuries, Larynx, Models, NEOMED College of Medicine, Newborn, Ohlemacher Jocelyn, Oropharynx, Pneumonia, Questionnaires, Swine
Impaired coronary metabolic dilation in the metabolic syndrome is linked to mitochondrial dysfunction and mitochondrial DNA damage.
Tags: 2016, Animal, Animals, Basic research in cardiology, Chen Chwen-Lih, Chen Yeong-Renn, Chilian William M, Coronary Circulation, Coronary microcirculation, Coronary Vessels/metabolism/*physiopathology, Department of Integrative Medical Sciences, Diabetes, Disease Models, DNA, DNA Damage/physiology, DNA Fragmentation, Dobson James G Jr, Fenton Richard, Guarini Giacinta, Hardwick James P, Kang Patrick T, Kiyooka Takahiko, Kolz Christopher L, Marzilli Mario, Metabolic Syndrome/metabolism/*physiopathology, Mitochondria, Mitochondria/*metabolism, Mitochondrial/*metabolism, NEOMED College of Medicine, Obesity, Ohanyan Vahagn, Oxidative Stress/physiology, Pung Yuh Fen, Rats, Reactive Oxygen Species/metabolism, Shokolenko Inna, Vasodilation/physiology, Wilson Glenn L, Yin Liya, Zucker
Reduced AMPK activation and increased HCAR activation drive anti-inflammatory response and neuroprotection in glaucoma.
Tags: 2018, AMP-activated protein kinase, AMP-Activated Protein Kinases/*metabolism, Animal, Animals, Biological, Calcium Binding Proteins – Metabolism, Calcium-Binding Proteins/metabolism, Cells – Drug Effects, Cells – Pathology, Department of Pharmaceutical Sciences, Diet, Disease Models, Eye Proteins/genetics, Female, G-Protein-Coupled – Metabolism, G-Protein-Coupled/*metabolism, Glaucoma, Glaucoma – Complications, Glaucoma – Pathology, Glaucoma/*complications/pathology, Harun-Or-Rashid Mohammad, Impact of Events Scale, Inbred DBA, Inflammation – Etiology, Inflammation – Prevention and Control, Inflammation hydroxycarboxylic acid receptor, Inflammation/*etiology/*prevention & control, Inman Denise M, Journal of neuroinflammation, Ketogenic diet, Ketogenic/methods, Male, Membrane Glycoproteins, Membrane Glycoproteins/genetics, Mice, Microfilament Proteins – Metabolism, Microfilament Proteins/metabolism, Microglia/drug effects/pathology, Models, Mutation, Mutation/genetics, NEOMED College of Pharmacy, Neuroprotection/drug effects/*physiology, NLR Family, Optic Nerve – Pathology, Optic Nerve/pathology, Phosphotransferases – Metabolism, Proteins, Pyrin Domain-Containing 3 Protein/genetics/metabolism, Receptors, Retina – Drug Effects, Retina – Pathology, Retinal Ganglion Cells/drug effects/*pathology, Transgenic
Qualitative skeletal correlates of wing shape in extant birds (Aves: Neoaves).
Tags: *Flight, 2015, Animal, Animal/*anatomy & histology/physiology, Animals, Biological Evolution, Birds/*anatomy & histology/classification/*physiology, BMC evolutionary biology, Bone and Bones/anatomy & histology, Department of Anatomy & Neurobiology, Feathers, Fossils, Hieronymus Tobin L, NEOMED College of Medicine, Phylogeny, Wings
Increased transperitoneal bacterial translocation in laparoscopic surgery.
Tags: *Bacterial Translocation, *Laparoscopy, 2003, Animal, Animals, Artificial/*adverse effects/methods, Carbon Dioxide/administration & dosage, Escherichia coli Infections/*microbiology, Escherichia coli/isolation & purification/physiology, Gases, Haller N, Helium/administration & dosage, Horattas M C, Insufflation/adverse effects, Male, Models, Peritonitis/*microbiology, Pneumoperitoneum, Pressure, Rats, Ricchiuti D, Sprague-Dawley, Surgical endoscopy
Acute exercise attenuates phenylephrine-induced contraction of rabbit isolated aortic rings.
Tags: *Physical Conditioning, 1992, Adrenergic, alpha/physiology, Animal, Animals, Aorta/physiology, DiCarlo S E, Dose-Response Relationship, Drug, Howard M G, In Vitro Techniques, Medicine and science in sports and exercise, Muscle, Muscle Contraction/*drug effects, Phenylephrine/*pharmacology, Rabbits, Receptors, Smooth, Stallone J N, Vascular/*drug effects/physiology
Alignment of inducible vascular progenitor cells on a micro-bundle scaffold improves cardiac repair following myocardial infarction.
Tags: *Cardiovascular regeneration, *Ischemic heart diseases, *Micro-bundle scaffold, *Myocardial infarction, *Neovascularization, *Stem cells, *Tissue Scaffolds, *Vascular progenitor cells, 2017, Animal, Animals, Basic research in cardiology, Cell Differentiation, Cell Proliferation, Cell Survival, Cells, Chilian William M, Coculture Techniques, Cultured, Cumpston Devan, Department of Integrative Medical Sciences, Disease Models, Dong Feng, Endothelial Progenitor Cells/metabolism/*transplantation, Enrick Molly, Fibroblast Growth Factor 2/metabolism, Hakobyan Tatev, Jamaiyar Anurag, Janota Danielle, Kolz Christopher L, Lactic Acid/*chemistry, Muscle, Myocardial Infarction/metabolism/pathology/physiopathology/*surgery, Myocardium/metabolism/*pathology, Myocytes, NEOMED College of Medicine, Newby Bi-Min Zhang, Ohanyan Vahagn, Paracrine Communication, Phenotype, Physiologic, Polyglycolic Acid/*chemistry, Polylactic Acid-Polyglycolic Acid Copolymer, Rats, Signal Transduction, Smooth, Smooth Muscle/metabolism/*transplantation, Song Hokyung, Sprague-Dawley, Stevanov Kelly, Time Factors, Tissue Engineering/*methods, Vascular Endothelial Growth Factor A/metabolism, Vascular/metabolism/*transplantation, Ventricular Remodeling, Wan Weiguo, Yin Liya
Impairment of pH gradient and membrane potential mediates redox dysfunction in the mitochondria of the post-ischemic heart.
Tags: *Energy Metabolism, *Membrane potential, *Mitochondria, *Myocardial ischemia and reperfusion, *Oxidative Stress, *pH gradient, *Redox dysfunction, 2017, Aconitate Hydratase/metabolism, Animal, Animals, Basic research in cardiology, Cell Line, Chen Chwen-Lih, Chen Yeong-Renn, Chilian William M, Department of Family & Community Medicine, Department of Integrative Medical Sciences, Disease Models, Electron Transport Chain Complex Proteins/metabolism, Heart/*metabolism/pathology, Hydrogen Peroxide/metabolism, Hydrogen-Ion Concentration, Ionophores/pharmacology, Kang Patrick T, Lin Paul, Male, Mitochondria, Mitochondrial, Myocardial Infarction/*metabolism/pathology, Myocardium/*metabolism/pathology, NEOMED College of Medicine, Oxidation-Reduction, Potassium/metabolism, Rats, Sprague-Dawley, Superoxides/metabolism
Effects of growth hormone transgene expression on vertebrae in a mouse model of osteogenesis imperfecta.
Tags: 2005, Animal, Animals, Beamer Wesley G, Biomechanical Phenomena, Bone Density, Chase Jeff, Department of Family & Community Medicine, Disease Models, Female, Gene Expression, Genetic Therapy/*methods, Havey Robert M, Heterozygote, Human Growth Hormone/*genetics, Humans, Inbred C57BL, King Donna, Male, McEwen Heather A, Mice, NEOMED College of Medicine, Osteogenesis Imperfecta/pathology/physiopathology/*therapy, Patwardhan Avinash G, Sartori Mark, Spine, Spine/pathology/*physiology, Tail, Transgenic, Voronov Leonard
Growth hormone injections improve bone quality in a mouse model of osteogenesis imperfecta.
Tags: 2005, Animal, Animals, Askew Michael J, Biomechanical Phenomena, Body Weight/drug effects, Bone and Bones/drug effects, Bone/prevention & control, Collagen Type I, Collagen/genetics, Densitometry, Department of Family & Community Medicine, Disease Models, Femur/drug effects/pathology, Fractures, Growth Hormone/*therapeutic use, Heterozygote, Humans, Inbred C57BL, Jarjoura David, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, King Donna, Lumbar Vertebrae/drug effects, McEwen Heather A, Mice, Mutation, NEOMED College of Medicine, Osteoblasts/*drug effects/metabolism, Osteogenesis Imperfecta/*drug therapy, Phenotype, Time Factors, Transgenic
Effects of vascular endothelial growth factor on wound closure rates in the genetically diabetic mouse model.
Tags: 2003, Administration, Angiogenesis Inducing Agents/*administration & dosage, Animal, Animals, Bulgrin Jeffery, College of Graduate Studies, Department of Pharmaceutical Sciences, Diabetes Mellitus/*physiopathology, Endothelial Growth Factors/*administration & dosage, Gruber Brian S, Intercellular Signaling Peptides and Proteins/*administration & dosage, Kirchner Loren M, Knoll Andrew K, Lymphokines/*administration & dosage, Meerbaum Sharon O, Mice, Models, NEOMED College of Graduate Studies, NEOMED College of Pharmacy, Schmidt Steven P, Taylor R A J, Topical, Vascular Endothelial Growth Factor A, Vascular Endothelial Growth Factors, Wound Healing/*drug effects, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
Altered Neuroinflammation and Behavior after Traumatic Brain Injury in a Mouse Model of Alzheimer's Disease.
Tags: 2016, Alzheimer Disease/etiology/*metabolism/pathology, Alzheimer's disease, Amyloid beta-Peptides/*metabolism, Animal, Animal/physiology, Animals, Behavior, Bemiller Shane M, Bhaskar Kiran, Blotting, Brain Injuries, Brain/*metabolism/pathology, Crish Samuel, Department of Pharmaceutical Sciences, Disease Models, Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Humans, Immunohistochemistry, Inbred C57BL, Inflammation/*metabolism/pathology, Journal of neurotrauma, Kokiko-Cochran Olga N, Lamb Bruce T, Lee Sungho, Lee Yu-Shang, macrophage, Mice, NEOMED College of Pharmacy, Neuroinflammation, Ransohoff Lena, Ransohoff Richard M, Saber Maha, Sikora Matt, Teknipp Ryan, Transgenic, Traumatic brain injury, Traumatic/complications/*metabolism/*pathology, Veenstra Mike, Western, Wilson Gina, Xu Guixiang
Weighted Lin-Wang tests for crossing hazards.
Tags: *Survival Analysis, 2014, Algorithms, Animal, Animals, Computational and mathematical methods in medicine, Computer Simulation, Data Interpretation, Disease Models, Humans, Jia Zhenyu, Kaplan-Meier Estimate, Koziol James A, Leukemia/drug therapy, Mice, Models, Reproducibility of Results, Statistical
Innate and adaptive host response during the initial phase of herpes simplex virus encephalitis in the neonatal mouse.
Tags: *Immunity, 2006, Active, Animal, Animals, B-Lymphocytes/immunology, Brain/pathology/*virology, Cell Line, Disease Models, Docherty John J, Encephalitis, Fu Ming Ming, Herpes Simplex/*immunology, Innate, Journal of neurovirology, Kumaraswamy Guttalu K, Mice, Microglia/pathology/virology, Newborn, Simplexvirus/*isolation & purification/physiology, T-Lymphocytes/immunology, Virus Replication
Renal Calcium Oxalate Deposits Induce a Pro-Atherosclerotic and Pro-Osteoporotic Response in Mice.
Tags: *CARDIOVASCULAR DISEASE, *Gene Expression Regulation, *KIDNEY STONES, *METABOLIC BONE DISEASE, *MURINE MODEL, 2017, Animal, Animals, Atherosclerosis/*metabolism/pathology, Barr-Beare Evan, Calcium Oxalate/*metabolism, Disease Models, Journal of cellular biochemistry, Kidney/*metabolism/pathology, Kusumi Kirsten, Mice, Osteoporosis/*metabolism/pathology, Safedi Fayez, Saxena Vijay, Schwaderer Andrew, Urinary Calculi/*metabolism/pathology
Adrenal epinephrine increases alveolar liquid clearance in a canine model of neurogenic pulmonary edema.
Tags: 1998, Adrenal Glands/*metabolism, Adrenalectomy, Adrenergic beta-Agonists/blood/*pharmacology/therapeutic use, Adrenergic beta-Antagonists/therapeutic use, American journal of respiratory and critical care medicine, Amiloride/therapeutic use, Animal, Animals, Awender N E, Blood, Blood Pressure, Brain Diseases/chemically induced/*complications, Central Nervous System Agents/adverse effects, Cisterna Magna, Disease Models, Diuretics/therapeutic use, Dogs, Epinephrine/blood/*physiology/therapeutic use, Extravascular Lung Water/chemistry/*metabolism, Female, Hypertension, Injections, Lane S M, Maender K C, Male, Maron M B, Propanolamines/therapeutic use, Proteins/analysis, Pulmonary Alveoli/*metabolism, Pulmonary Artery, Pulmonary Edema/etiology/*metabolism/prevention & control, Pulmonary/prevention & control, Sodium Channel Blockers, Veratrine/adverse effects
A Western diet induced NAFLD in LDLR(-/)(-) mice is associated with reduced hepatic glutathione synthesis.
Tags: *Flux, *Glutathione, *Heavy water, *Mass spectrometer, *NAFLD, *NASH, *Oxidative Stress, *Western Diet, 2016, Animal, Animals, Antioxidants/metabolism, Department of Pharmaceutical Sciences, Diet, Disease Models, Free radical biology & medicine, Glutathione/blood/*metabolism, Humans, Kasumov Takhar, LDL/blood/*genetics/metabolism, Lee Kwangwon, Li Ling, Liver/*metabolism/pathology, Lopez Rocio, McCullough Arthur, Mice, NEOMED College of Pharmacy, Non-alcoholic Fatty Liver Disease/blood/*genetics/pathology, Oxidative Stress/genetics, Previs Stephen F, Receptors, Western/adverse effects, Willard Belinda, Zhang Guo-Fang
Regulation of cholesterol and bile acid homeostasis by the cholesterol 7alpha-hydroxylase/steroid response element-binding protein 2/microRNA-33a axis in mice.
Tags: 2013, Acetyl Coenzyme A/metabolism, Animal, Animals, Bile Acids and Salts/*metabolism, Boehme Shannon, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/genetics/*metabolism, Cholesterol/*metabolism, Department of Integrative Medical Sciences, Francl Jessica M, Hepatology (Baltimore, Md.), Homeostasis/*physiology, Knockout, Li Tiangang, Lipid Metabolism/physiology, Liver/metabolism, Male, Messenger/metabolism, Mice, MicroRNAs/*metabolism, Models, NEOMED College of Medicine, RNA, Signal Transduction/*physiology, Sterol Regulatory Element Binding Protein 2/*metabolism, Transgenic
Modulating ryanodine receptors with dantrolene attenuates neuronopathic phenotype in Gaucher disease mice.
Tags: 2016, Animal, Animals, Blackwood Rachel, Calcium Signaling/genetics, Dantrolene/*administration & dosage, Dasgupta Nupur, Department of Pharmaceutical Sciences, Disease Models, Fleming Sheila, Gaucher Disease/*drug therapy/genetics/physiopathology, Grabowski Gregory A, Human molecular genetics, Humans, Inskeep Venette, Li Ronghua, Liou Benjamin, Marshall John, Mice, Mitochondria/*drug effects/genetics/pathology, NEOMED College of Pharmacy, Neurons/drug effects/pathology, Neuroprotective Agents/administration & dosage, Peng Yanyan, Quinn Brian, Ryanodine Receptor Calcium Release Channel/*genetics/metabolism, Setchell Kenneth D R, Sun Ying, Zhang Wujuan
Effect of estrogen upon methamphetamine-induced neurotoxicity within the impaired nigrostriatal dopaminergic system.
Tags: 2006, 3, 4-Dihydroxyphenylacetic Acid/metabolism, Adrenergic Uptake Inhibitors/antagonists & inhibitors/toxicity, Animal, Animals, Corpus Striatum/*drug effects/metabolism/physiopathology, Disease Models, Dluzen Dean E, Dopamine/metabolism, Estrogens/metabolism/*pharmacology/therapeutic use, Female, Liu Bin, Male, Methamphetamine/*antagonists & inhibitors/toxicity, Mice, Nerve Degeneration/chemically induced/*drug therapy/prevention & control, Neural Pathways/drug effects/metabolism/physiopathology, Neuroprotective Agents/metabolism/*pharmacology/therapeutic use, Neurotoxins/antagonists & inhibitors/toxicity, Orchiectomy, Ovariectomy, Parkinsonian Disorders/*drug therapy/physiopathology/prevention & control, Substantia Nigra/*drug effects/metabolism/physiopathology, Synapse (New York, N.Y.)
Oestrogen and nigrostriatal dopaminergic neurodegeneration: animal models and clinical reports of Parkinson's disease.
Tags: 2007, Animal, Animals, Basal Ganglia/drug effects/*metabolism/pathology, Clinical and experimental pharmacology & physiology, Disease Models, Dluzen Dean E, Dopamine/*metabolism, Estrogens/*metabolism/pharmacology/therapeutic use, Humans, Liu Bin, Nerve Degeneration/drug therapy/*metabolism/pathology, Neurons/metabolism/pathology, Neuroprotective Agents/*metabolism/pharmacology/therapeutic use, Parkinson Disease/drug therapy/*metabolism/pathology, Parkinsonian Disorders/drug therapy/*metabolism/pathology, Substantia Nigra/drug effects/*metabolism/pathology
Suppression of acute proinflammatory cytokine and chemokine upregulation by post-injury administration of a novel small molecule improves long-term neurologic outcome in a mouse model of traumatic brain injury.
Tags: 2008, Animal, Animals, Brain Injuries/blood/epidemiology/genetics/*physiopathology, Cerebral Cortex/physiopathology, Chemokine CCL2/genetics/physiology, Chemokines/*genetics, Cytokines/*antagonists & inhibitors, Disease Models, Hippocampus/physiopathology, Inflammation/genetics/*physiopathology, Interleukin-1beta/genetics/physiology, Interleukin-6/genetics/physiology, Journal of neuroinflammation, Lloyd Eric, Male, Mice, Somera-Molina Kathleen, Tumor Necrosis Factor-alpha/genetics/physiology, United States/epidemiology, Up-Regulation, Van Eldik Linda J, Wainwright Mark S, Watterson D Martin
Prepulse inhibition of the acoustic startle reflex vs. auditory brainstem response for hearing assessment.
Tags: *Audiometric functions, *Hearing loss, *Mouse, *Permanent threshold shift, *Sound exposure, *Temporary threshold shift, 2016, Acoustic Stimulation/*methods, Alghamdi F, Animal, Animals, Audiometry, Auditory, Auditory Threshold/*physiology, Brain Stem/*physiology, Department of Anatomy & Neurobiology, Evoked Potentials, Galazyuk A V, Hearing, Hearing research, Inbred CBA, Longenecker R J, Male, Mice, Models, NEOMED College of Medicine, Noise, Prepulse Inhibition/*physiology, Pure-Tone/*methods, Reflex, Rosen M J, Startle/*physiology
Chemopreventive doses of resveratrol do not produce cardiotoxicity in a rodent model of hepatocellular carcinoma.
Tags: *Chemoprevention, 2011, Analysis of Variance, Animal, Animal Studies, Animal/drug effects, Animals, Antioxidants, Behavior, Bishayee Anupam, Blotting, Booth Tristan D, Carcinoma, Cardiotoxicity, Cardiotoxins/*toxicity, Chemoprevention, Data Analysis Software, Department of Integrative Medical Sciences, Descriptive Statistics, Disease Models, Doppler, Dose-Response Relationship, Drug, Echocardiography, Feeding Behavior/drug effects, Female, Fisher's Exact Test, Funding Source, Heart – Drug Effects, Heart/drug effects/physiopathology, Hepatocellular – Prevention and Control, Hepatocellular/*drug therapy/pathology/physiopathology, Hepatocytes/drug effects/pathology, Hodnichak Cheryl M, Humans, Investigational new drugs, Liver Neoplasms/*drug therapy/pathology/physiopathology, Liver/drug effects/pathology/physiopathology, Luther Daniel J, Meszaros J Gary, NEOMED College of Medicine, Ohanyan Vahagn, Polyphenols – Therapeutic Use, Rats, Resveratrol, Shamhart Patricia E, Sisakian Hamayak, Sprague-Dawley, Stilbenes/*therapeutic use, Systole/drug effects, Western
Injury models to study cardiac remodeling in the mouse: myocardial infarction and ischemia-reperfusion.
Tags: *Ventricular Remodeling, 2013, Animal, Animals, Cardiovascular Surgical Procedures, Coronary Vessels/surgery, Department of Integrative Medical Sciences, Disease Models, Ligation, Luther Daniel J, Meszaros J Gary, Methods in molecular biology (Clifton, N.J.), Mice, Myocardial Infarction/*etiology/*pathology, Myocardial Reperfusion Injury/*etiology/*pathology, NEOMED College of Medicine, Perfusion/methods, Thodeti Charles K, Wound Healing
Absence of type VI collagen paradoxically improves cardiac function, structure, and remodeling after myocardial infarction.
Tags: 2012, Adapala Ravi K, Animal, Animals, Apoptosis/physiology, Bonaldo Paolo, Cardiac/pathology/physiology, Chilian William M, Circulation research, Collagen Type VI/*genetics/*metabolism, Department of Integrative Medical Sciences, Disease Models, Echocardiography, Extracellular Matrix/metabolism/pathology, Fibrosis/genetics/pathology/physiopathology, Hodnichak Cheryl, Knockout, Luther Daniel J, Male, Meszaros J Gary, Mice, Myocardial Infarction/diagnostic imaging/*genetics/*physiopathology, Myocytes, NEOMED College of Medicine, Shamhart Patricia E, Thodeti Charles K, Ventricular Remodeling/*physiology, Weihrauch Dorothee
Pulmonary vasoconstriction in a canine model of neurogenic pulmonary edema.
Tags: 1990, Animal, Animals, Catecholamines/physiology, Disease Models, Dogs, Female, Hypertension, In Vitro Techniques, Journal of applied physiology (Bethesda, Md. : 1985), Male, Maron M B, Perfusion, Pulmonary Circulation/drug effects/*physiology, Pulmonary Edema/chemically induced/*physiopathology, Pulmonary/chemically induced/physiopathology, Splenectomy, Sympathetic Nervous System/drug effects/physiopathology, Vasoconstriction/drug effects/*physiology, Veratrine
Early upregulation of myocardial CXCR4 expression is critical for dimethyloxalylglycine-induced cardiac improvement in acute myocardial infarction.
Tags: 2016, alpha Subunit/metabolism, American journal of physiology. Heart and circulatory physiology, Amino Acids, Animal, Animals, Apoptosis/drug effects, Cardiotonic Agents/*pharmacology, Cell Hypoxia, Cell Line, Chilian William M, CXCR4/deficiency/genetics/*metabolism, Department of Integrative Medical Sciences, Dicarboxylic/*pharmacology, Disease Models, Dong Feng, Enzyme Inhibitors/pharmacology, Forudi Farhad, hypoxia, Hypoxia-Inducible Factor 1, Hypoxia-Inducible Factor-Proline Dioxygenases/antagonists & inhibitors/metabolism, Inbred C57BL, Kiedrowski Matthew, Knockout, Left/*drug effects, Mayorga Mari, Mice, myocardial infarction, Myocardial Infarction/*drug therapy/genetics/metabolism/pathology/physiopathology, Myocardium/*metabolism/pathology, NEOMED College of Medicine, Penn Marc S, Rats, Receptors, Recovery of Function, Shamhart Patricia, Signal Transduction/drug effects, stem cells, Stem Cells/drug effects/metabolism, Stroke Volume/drug effects, Time Factors, Up-Regulation, Ventricular Function, Weber Kristal
Isolation of canine coronary sinus musculature from the atria by radiofrequency catheter ablation prevents induction of atrial fibrillation.
Tags: *Catheter Ablation, 2014, Acetylcholine, Action Potentials, Animal, Animal Studies, Animals, Artificial, Atrial fibrillation, Atrial Fibrillation – Etiology, Atrial Fibrillation – Physiopathology, Atrial Fibrillation – Prevention and Control, Atrial Fibrillation/etiology/physiopathology/*prevention & control, Biological, Body Surface Potential Mapping, Cardiac Pacing, Catheter Ablation, Circulation. Arrhythmia and electrophysiology, coronary sinus, Coronary Sinus/physiopathology/*surgery, Coronary Vessels – Physiopathology, Coronary Vessels – Surgery, Disease Models, Dogs, Heart Atria/physiopathology/surgery, Heart Atrium – Physiopathology, Heart Atrium – Surgery, Male, Models, Morita Hiroshi, Morita Shiho T, optical Vm mapping, Time Factors, Wu Jiashin, Zipes Douglas P
Responses in the inferior colliculus of the guinea pig to concurrent harmonic series and the effect of inactivation of descending controls.
Tags: *Acoustic Stimulation, 2010, Action Potentials/physiology, Animal, Animals, Auditory Cortex/*physiology, Auditory Pathways/*physiology, Female, Guinea Pigs, Inferior Colliculi/*physiology, Journal of neurophysiology, Male, Models, Nakamoto Kyle T, Palmer Alan R, Pitch Perception/physiology, Shackleton Trevor M
Injury-induced gp130 cytokine signaling in peripheral ganglia is reduced in diabetes mellitus.
Tags: *Axon regeneration, *Axotomy, *Diabetes, *Neuropathy, *Peripheral nervous system, 2017, Animal, Animals, Antibiotics, Antineoplastic/toxicity, Blood Glucose/drug effects, Body Weight/drug effects, Crish Samuel D, Cytokine Receptor gp130/genetics/*metabolism, Cytokines/metabolism, DeFrancesco Alicia, Department of Pharmaceutical Sciences, Diabetes Mellitus, Disease Models, Experimental neurology, Experimental/chemically induced/complications/*pathology, Fasting/blood, Filous Angela R, Gene Expression Regulation/*physiology, Hyperalgesia/etiology, Hyperglycemia/etiology, Inbred C57BL, Lindborg Jane A, Male, Malhotra Nisha A, Mice, NEOMED College of Pharmacy, Nerve Degeneration/*etiology/pathology, Nerve Tissue Proteins/metabolism, Niemi Jon P, Pain Measurement, Signal Transduction/drug effects/*physiology, Streptozocin/toxicity, Superior Cervical Ganglion/drug effects/*metabolism, Sweating/drug effects, Wilson Gina N, Zhou Bowen, Zigmond Richard E
Endothelin-mediated in vivo pressor responses following TRPV1 activation.
Tags: *Blood Pressure/drug effects, *Vasoconstriction/drug effects, 2011, Adrenergic alpha-Agonists/administration & dosage, American journal of physiology. Heart and circulatory physiology, Analysis of Variance, Animal, Animals, Azepines/administration & dosage, Biphenyl Compounds/administration & dosage, Bratz Ian N, Capsaicin/administration & dosage, Cells, Cultured, Damron Derek S, Department of Integrative Medical Sciences, Diabetes Mellitus, Diabetic Angiopathies/genetics/*metabolism/physiopathology, Dipeptides/administration & dosage, Disease Models, Dose-Response Relationship, Drug, Endothelial Cells/metabolism, Endothelin A Receptor Antagonists, Endothelin A/metabolism, Endothelin B Receptor Antagonists, Endothelin B/metabolism, Endothelin-1/*metabolism, Enzyme-Linked Immunosorbent Assay, Femoral Artery/drug effects/*metabolism/physiopathology, Guarini Giacinta, Haney Rebecca M, Inbred C57BL, Indoles/administration & dosage, Infusions, Intravenous, Knockout, Male, Meszaros J Gary, Mice, NEOMED College of Medicine, Ohanyan Vahagn A, Phenylephrine/administration & dosage, Raman Priya, Receptor, Talasila Phani K, Thodeti Charles K, TRPV Cation Channels/agonists/deficiency/genetics/*metabolism, Type 2/genetics/*metabolism/physiopathology, Vasoconstrictor Agents/administration & dosage
Intestine farnesoid X receptor agonist and the gut microbiota activate G-protein bile acid receptor-1 signaling to improve metabolism.
Tags: *Signal Transduction, 2018, Animal, Animals, Bile Acids and Salts/*metabolism, Boehme Shannon, Chiang John Y L, Cytoplasmic and Nuclear/*antagonists & inhibitors/pharmacology, Department of Integrative Medical Sciences, Disease Models, Ferrell Jessica M, G-Protein-Coupled/*metabolism, Gastrointestinal Microbiome/*drug effects, Glucagon-Like Peptide 1/metabolism, Gonzalez Frank J, GTP-Binding Proteins/*metabolism, Hepatology (Baltimore, Md.), Inbred C57BL, Krausz Kristopher W, Lipid Metabolism, Male, Mice, NEOMED College of Medicine, Nichols Robert G, Pathak Preeti, Patterson Andrew D, Random Allocation, Receptors, Sensitivity and Specificity, Xie Cen
Excitatory and facilitatory frequency response areas in the inferior colliculus of the mustached bat.
Tags: 2002, Acoustic Stimulation, Animal, Animals, Auditory, Auditory Perception/*physiology, Brain Stem, Chiroptera/*physiology, College of Anatomy & Neurobiology, Department of Anatomy & Neurobiology, Echolocation, Evoked Potentials, Hearing research, Inferior Colliculi/*physiology, NEOMED College of Medicine, Neurons/physiology, Portfors Christine V, Vocalization, Wenstrup Jeffrey J
The JCR:LA-cp rat: a novel rodent model of cystic medial necrosis.
Tags: *Rats, 2017, American journal of physiology. Heart and circulatory physiology, Animal, Animals, Aortic Aneurysm, Atherosclerosis/pathology, Bennett Martin R, Blood Glucose/metabolism, Blood Vessels/pathology, Body Weight, Chilian William M, Collagen/biosynthesis, Cysts/*genetics/pathology, Department of Integrative Medical Sciences, Disease Models, Figg Nichola, hypoxia, Inbred Strains, Kamarulzaman Mohd Hamzah, leptin, Lipids/blood, Male, Metabolic syndrome, Metabolic Syndrome/*genetics/pathology, Necrosis, NEOMED College of Medicine, Proteoglycans/biosynthesis, Pung Yuh Fen, Rats, rodent model, Thoracic/*genetics/pathology
Resolution of mitochondrial oxidative stress rescues coronary collateral growth in Zucker obese fatty rats.
Tags: 2012, Animal, Animals, Antioxidants/*pharmacology, Arteriosclerosis, thrombosis, and vascular biology, Chilian William M, Collateral Circulation/*drug effects/physiology, Coronary Vessels/drug effects/*growth & development, Department of Integrative Medical Sciences, Disease Models, Guarini Giacinta, Hafemeister Jennifer, Heart/*drug effects/physiology, Lipid Peroxidation/drug effects/physiology, Lipid Peroxides/metabolism, Male, Metabolic Syndrome/*metabolism/physiopathology, Mitochondria, Mitochondrial Proteins/metabolism, Murphy Michael P, NEOMED College of Medicine, Obesity/*metabolism/physiopathology, Ohanyan Vahagn, Organophosphorus Compounds/pharmacology, Oxidative Stress/*drug effects/physiology, Piperidines/pharmacology, Pung Yuh Fen, Rats, Reactive Oxygen Species/metabolism, Rocic Petra, Smith Robin A J, Ubiquinone/pharmacology, Yin Liya, Zucker